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The map label for this gene is aspB [H]

Identifier: 154686484

GI number: 154686484

Start: 2153010

End: 2154191

Strand: Reverse

Name: aspB [H]

Synonym: RBAM_020520

Alternate gene names: 154686484

Gene position: 2154191-2153010 (Counterclockwise)

Preceding gene: 154686485

Following gene: 154686483

Centisome position: 54.97

GC content: 49.58

Gene sequence:

>1182_bases
TTGAAATTGGCAAAAAGAGTATCCGCATTAACACCGTCTGCAACACTTGCAATTACTGCAAAAGCGAAAGAGCTGAAAGC
AGAAGGCCATGATGTCATCGGCCTCGGAGCAGGAGAACCGGATTTTAATACGCCTCAGCACATTATAGATGCCGCGGTGC
GTTCCATGAATGAAGGCCATACGAAATATACGCCTTCAGGCGGTCTGCCGGCGCTGAAAGACAGTATCGCAAAAAAATTC
AAAAACGACCAGGGGATTGAATATAAGCCGTCAGAAATCATTGTCTGCACCGGAGCGAAACACGCTCTGTATACATTATT
TCAGGTTATTCTCGATGAAGGGGACGAAGTGATTATACCGACTCCTTACTGGGTCAGCTACCCTGAGCAGGTGAAACTGG
CAGGGGGGCGTCCCGTCTATGCAGAAGGGCTGGAATCCAATCAGTTTAAAATTTCACCGGAGCAGCTGAAGCAGGCTATC
ACGGAGAAAACAAAAGCGCTCATTATCAATTCACCGAGCAACCCGACAGGTGTTATGTATACGAAAGAAGAGCTTGCGGA
ACTCGGAAAAGTGTGTCTGGAGCATGGCATTCTGATCGTTTCTGACGAGATTTATGAGAAGCTTACATACGGAGGAAAAA
AACACGTCTCAATCGCACAGCTTTCAGGTGAATTGAAAGAGCAGACGATCATCATTAACGGCGTGTCGAAATCTCACAGC
ATGACGGGCTGGAGGATCGGCTATGCGGCGGGTTCGGAGACGATTATTAAAGCGATGACGAGCCTTGCGAGCCACAGCAC
ATCAAATCCGACGTCCATCGCTCAATACGGCGCTATTGCGGCCTATAACGGGCCGGCTGAGCCGCTGGAAGAGATGAGAC
AGGCATTTGAGCACAGACTGAACACCATTTACGCTCAGCTCAGTGAGATTCCCGGATTCACCTGTGTCAAGCCTGAAGGG
GCGTTTTACTTGTTCCCTAACGCCAAAGCGGCCGCAGAAAACTGTGGATTCAAAGATGTCGATGAATACGTCAAGGCGCT
TCTGGAAGAAGAAAAAGTCGCCGTCGTGCCGGGCTCGGGTTTCGGTTCACCGGACAACGTCCGCTTATCTTACGCAACGT
CACTCGATCTTTTAGAAGAAGCGGTCGAAAGAATCCGCCGCTTCACGGAAAAACACAGCTGA

Upstream 100 bases:

>100_bases
ATCAACAAAAGCGGGCAGTATAGCTTTAGCTATGTGGACTTTACAAGCGGCAAGATTCTCAAAAACATCACACCGTGAGA
CGTATTAGGGGGAGTTCAAG

Downstream 100 bases:

>100_bases
TTCTGAAAAAGCGGCTTTTAAAGCCGCTTTTCACTTGCATTGACCCCGTTAGAGTAGAACGGGTATAATAAAGTGATGAA
AAAAGAGATTCAGGCAGATT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKLAKRVSALTPSATLAITAKAKELKAEGHDVIGLGAGEPDFNTPQHIIDAAVRSMNEGHTKYTPSGGLPALKDSIAKKF
KNDQGIEYKPSEIIVCTGAKHALYTLFQVILDEGDEVIIPTPYWVSYPEQVKLAGGRPVYAEGLESNQFKISPEQLKQAI
TEKTKALIINSPSNPTGVMYTKEELAELGKVCLEHGILIVSDEIYEKLTYGGKKHVSIAQLSGELKEQTIIINGVSKSHS
MTGWRIGYAAGSETIIKAMTSLASHSTSNPTSIAQYGAIAAYNGPAEPLEEMRQAFEHRLNTIYAQLSEIPGFTCVKPEG
AFYLFPNAKAAAENCGFKDVDEYVKALLEEEKVAVVPGSGFGSPDNVRLSYATSLDLLEEAVERIRRFTEKHS

Sequences:

>Translated_393_residues
MKLAKRVSALTPSATLAITAKAKELKAEGHDVIGLGAGEPDFNTPQHIIDAAVRSMNEGHTKYTPSGGLPALKDSIAKKF
KNDQGIEYKPSEIIVCTGAKHALYTLFQVILDEGDEVIIPTPYWVSYPEQVKLAGGRPVYAEGLESNQFKISPEQLKQAI
TEKTKALIINSPSNPTGVMYTKEELAELGKVCLEHGILIVSDEIYEKLTYGGKKHVSIAQLSGELKEQTIIINGVSKSHS
MTGWRIGYAAGSETIIKAMTSLASHSTSNPTSIAQYGAIAAYNGPAEPLEEMRQAFEHRLNTIYAQLSEIPGFTCVKPEG
AFYLFPNAKAAAENCGFKDVDEYVKALLEEEKVAVVPGSGFGSPDNVRLSYATSLDLLEEAVERIRRFTEKHS
>Mature_393_residues
MKLAKRVSALTPSATLAITAKAKELKAEGHDVIGLGAGEPDFNTPQHIIDAAVRSMNEGHTKYTPSGGLPALKDSIAKKF
KNDQGIEYKPSEIIVCTGAKHALYTLFQVILDEGDEVIIPTPYWVSYPEQVKLAGGRPVYAEGLESNQFKISPEQLKQAI
TEKTKALIINSPSNPTGVMYTKEELAELGKVCLEHGILIVSDEIYEKLTYGGKKHVSIAQLSGELKEQTIIINGVSKSHS
MTGWRIGYAAGSETIIKAMTSLASHSTSNPTSIAQYGAIAAYNGPAEPLEEMRQAFEHRLNTIYAQLSEIPGFTCVKPEG
AFYLFPNAKAAAENCGFKDVDEYVKALLEEEKVAVVPGSGFGSPDNVRLSYATSLDLLEEAVERIRRFTEKHS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=399, Percent_Identity=28.3208020050125, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI169881279, Length=399, Percent_Identity=28.3208020050125, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI56713254, Length=426, Percent_Identity=27.4647887323944, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI56713256, Length=425, Percent_Identity=27.0588235294118, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI169881281, Length=396, Percent_Identity=24.7474747474747, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI4507369, Length=385, Percent_Identity=25.7142857142857, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI4885351, Length=344, Percent_Identity=24.1279069767442, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI19263340, Length=367, Percent_Identity=23.9782016348774, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI215599424, Length=367, Percent_Identity=23.9782016348774, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI187936925, Length=225, Percent_Identity=27.5555555555556, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI14211921, Length=225, Percent_Identity=27.5555555555556, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1788627, Length=384, Percent_Identity=29.1666666666667, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1788722, Length=395, Percent_Identity=29.873417721519, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786816, Length=376, Percent_Identity=28.1914893617021, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787909, Length=368, Percent_Identity=23.0978260869565, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI48994949, Length=315, Percent_Identity=25.3968253968254, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=426, Percent_Identity=30.5164319248826, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71994472, Length=426, Percent_Identity=30.5164319248826, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17567369, Length=396, Percent_Identity=29.040404040404, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17567663, Length=375, Percent_Identity=27.2, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71981209, Length=369, Percent_Identity=23.3062330623306, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=393, Percent_Identity=28.7531806615776, Blast_Score=159, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6320317, Length=340, Percent_Identity=26.1764705882353, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323118, Length=375, Percent_Identity=26.4, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573069, Length=418, Percent_Identity=26.7942583732057, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24646114, Length=418, Percent_Identity=26.7942583732057, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28573067, Length=418, Percent_Identity=26.7942583732057, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28573065, Length=418, Percent_Identity=26.7942583732057, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=25.78125, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24641770, Length=391, Percent_Identity=24.5524296675192, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641760, Length=391, Percent_Identity=24.5524296675192, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641768, Length=391, Percent_Identity=24.5524296675192, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641766, Length=391, Percent_Identity=24.5524296675192, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641764, Length=391, Percent_Identity=24.5524296675192, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45551451, Length=391, Percent_Identity=24.5524296675192, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42706; Mature: 42706

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAKRVSALTPSATLAITAKAKELKAEGHDVIGLGAGEPDFNTPQHIIDAAVRSMNEGH
CCHHHHHHHCCCCCEEEEEECHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
TKYTPSGGLPALKDSIAKKFKNDQGIEYKPSEIIVCTGAKHALYTLFQVILDEGDEVIIP
CEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEC
TPYWVSYPEQVKLAGGRPVYAEGLESNQFKISPEQLKQAITEKTKALIINSPSNPTGVMY
CCCCCCCCCCEEECCCCEEEECCCCCCCEEECHHHHHHHHHHCCEEEEEECCCCCCEEEE
TKEELAELGKVCLEHGILIVSDEIYEKLTYGGKKHVSIAQLSGELKEQTIIINGVSKSHS
EHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCEEHHHHHCCCCCCEEEEECCCCCCC
MTGWRIGYAAGSETIIKAMTSLASHSTSNPTSIAQYGAIAAYNGPAEPLEEMRQAFEHRL
CCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHCCEEECCCCHHHHHHHHHHHHHHH
NTIYAQLSEIPGFTCVKPEGAFYLFPNAKAAAENCGFKDVDEYVKALLEEEKVAVVPGSG
HHHHHHHHHCCCCEEECCCCCEEECCCCHHHHHCCCCCCHHHHHHHHHCCCCEEEECCCC
FGSPDNVRLSYATSLDLLEEAVERIRRFTEKHS
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLAKRVSALTPSATLAITAKAKELKAEGHDVIGLGAGEPDFNTPQHIIDAAVRSMNEGH
CCHHHHHHHCCCCCEEEEEECHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
TKYTPSGGLPALKDSIAKKFKNDQGIEYKPSEIIVCTGAKHALYTLFQVILDEGDEVIIP
CEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEC
TPYWVSYPEQVKLAGGRPVYAEGLESNQFKISPEQLKQAITEKTKALIINSPSNPTGVMY
CCCCCCCCCCEEECCCCEEEECCCCCCCEEECHHHHHHHHHHCCEEEEEECCCCCCEEEE
TKEELAELGKVCLEHGILIVSDEIYEKLTYGGKKHVSIAQLSGELKEQTIIINGVSKSHS
EHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCEEHHHHHCCCCCCEEEEECCCCCCC
MTGWRIGYAAGSETIIKAMTSLASHSTSNPTSIAQYGAIAAYNGPAEPLEEMRQAFEHRL
CCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHCCEEECCCCHHHHHHHHHHHHHHH
NTIYAQLSEIPGFTCVKPEGAFYLFPNAKAAAENCGFKDVDEYVKALLEEEKVAVVPGSG
HHHHHHHHHCCCCEEECCCCCEEECCCCHHHHHCCCCCCHHHHHHHHHCCCCEEEECCCC
FGSPDNVRLSYATSLDLLEEAVERIRRFTEKHS
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]