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The map label for this gene is asnC

Identifier: 154686483

GI number: 154686483

Start: 2151583

End: 2152875

Strand: Reverse

Name: asnC

Synonym: RBAM_020510

Alternate gene names: 154686483

Gene position: 2152875-2151583 (Counterclockwise)

Preceding gene: 154686484

Following gene: 154686482

Centisome position: 54.94

GC content: 46.17

Gene sequence:

>1293_bases
TTGAAAACAACAATCAACCAAGTGTATAAACACACAGGCGAGGAAGTAATGATTGGAGCTTGGGTCGCTAATAAACGCTC
AAGCGGTAAAATCGCATTTTTACAGCTGAGAGACGGTACCGGCTTCATTCAGGGAGTTGTCGTCAAAGCTGAAGTAGAAG
AAGACATCTTCCAAATCGCGAAATCAGTGACGCAGGAAACGTCACTTTATGTAAAAGGAATTGTGAAAGAGGACGAGCGT
TCACCGCTTGGCTATGAGCTTGCTGTTACATCCATTGAAGTCATTCACGAAGCGACTGATTATCCGATTACGCCTAAAGA
GCACGGTACGGAATTCTTAATGGATCACAGACATTTATGGCTCCGTTCGAAACGCCAGCACGCAATTATGAAAATCCGCA
ACGAAATCATCCGTGCGACTTATGAATTTTTCAACAAAGAAGGCTTCGTGAAAGTTGATCCGCCGATTTTGACGGGAAGC
GCTCCGGAAGGCACGACTGAGCTGTTCGCGACGAAATATTTTGATGAAGACGCCTTCTTGTCTCAAAGCGGCCAGCTGTA
TATGGAAGCAGCTGCAATGGCGCTCGGAAAAGTATTCTCTTTCGGACCGACGTTCAGAGCGGAAAAATCGAAAACGAAAC
GCCATCTCATCGAATTCTGGATGATTGAGCCTGAAATGGCATTTGTTGAATTTGAAGAAAACCTTGAAGTTCAGGAGAAT
TATGTTGCATACATCGTACAAAGTGTGCTGGAACATTGTAAGATCGAGCTGAACACATTAGGGAGAGACACATCGAAGCT
TGAGCAAATCAAAGCGCCATTCCCGCGCATTACGTACGATAAAGCGATCGAATTCCTGAAAGAAAAAGGCTTTGACGATA
TTGAGTGGGGAGATGACTTCGGTGCGCCGCATGAAACAGCGATCGCAGAAAGCTATGACAAACCGGTGTTTATCACTCAT
TACCCGACGTCATTAAAACCGTTTTATATGCAGCCTGCCAAAGATCGTGACGATGTCGTGTTATGTGCCGACTTAATCGC
TCCGGAAGGCTACGGGGAAATCATCGGCGGTTCAGAACGCGTTCATGATATGGATTTATTGGAAGAAAGATTAAAAGAAC
ACGGTCTGGATTCAGATGCTTACAAATGGTATGCTGAACTCAGACAATACGGTTCTGTTCCGCACTCCGGCTTCGGCCTC
GGACTTGAGCGGACAGTGGCTTGGATCAGCGGAGCGCCTCACGTGCGTGAAACAATTCCGTTCCCGAGACTTCTGAACCG
TCTGTATCCGTAA

Upstream 100 bases:

>100_bases
TTGCATTGACCCCGTTAGAGTAGAACGGGTATAATAAAGTGATGAAAAAAGAGATTCAGGCAGATTCCTGAATGTCTTTC
TTGTTCTGGAGGGAAAGAGT

Downstream 100 bases:

>100_bases
TAGTTTTAAAAAACGAAGTCTCCTGCAAGGGAGACTTTTTCTAAGTAAAGGGGAAAGCTCCCGGAGATAACCTTTTACAG
TAAGAGGTGTAAGGATGAAA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKTTINQVYKHTGEEVMIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEEDIFQIAKSVTQETSLYVKGIVKEDER
SPLGYELAVTSIEVIHEATDYPITPKEHGTEFLMDHRHLWLRSKRQHAIMKIRNEIIRATYEFFNKEGFVKVDPPILTGS
APEGTTELFATKYFDEDAFLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLEVQEN
YVAYIVQSVLEHCKIELNTLGRDTSKLEQIKAPFPRITYDKAIEFLKEKGFDDIEWGDDFGAPHETAIAESYDKPVFITH
YPTSLKPFYMQPAKDRDDVVLCADLIAPEGYGEIIGGSERVHDMDLLEERLKEHGLDSDAYKWYAELRQYGSVPHSGFGL
GLERTVAWISGAPHVRETIPFPRLLNRLYP

Sequences:

>Translated_430_residues
MKTTINQVYKHTGEEVMIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEEDIFQIAKSVTQETSLYVKGIVKEDER
SPLGYELAVTSIEVIHEATDYPITPKEHGTEFLMDHRHLWLRSKRQHAIMKIRNEIIRATYEFFNKEGFVKVDPPILTGS
APEGTTELFATKYFDEDAFLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLEVQEN
YVAYIVQSVLEHCKIELNTLGRDTSKLEQIKAPFPRITYDKAIEFLKEKGFDDIEWGDDFGAPHETAIAESYDKPVFITH
YPTSLKPFYMQPAKDRDDVVLCADLIAPEGYGEIIGGSERVHDMDLLEERLKEHGLDSDAYKWYAELRQYGSVPHSGFGL
GLERTVAWISGAPHVRETIPFPRLLNRLYP
>Mature_430_residues
MKTTINQVYKHTGEEVMIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEEDIFQIAKSVTQETSLYVKGIVKEDER
SPLGYELAVTSIEVIHEATDYPITPKEHGTEFLMDHRHLWLRSKRQHAIMKIRNEIIRATYEFFNKEGFVKVDPPILTGS
APEGTTELFATKYFDEDAFLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLEVQEN
YVAYIVQSVLEHCKIELNTLGRDTSKLEQIKAPFPRITYDKAIEFLKEKGFDDIEWGDDFGAPHETAIAESYDKPVFITH
YPTSLKPFYMQPAKDRDDVVLCADLIAPEGYGEIIGGSERVHDMDLLEERLKEHGLDSDAYKWYAELRQYGSVPHSGFGL
GLERTVAWISGAPHVRETIPFPRLLNRLYP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=439, Percent_Identity=35.3075170842825, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI4758762, Length=445, Percent_Identity=32.8089887640449, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI45439306, Length=452, Percent_Identity=31.1946902654867, Blast_Score=181, Evalue=9e-46,
Organism=Homo sapiens, GI40789249, Length=236, Percent_Identity=27.1186440677966, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1787161, Length=447, Percent_Identity=36.9127516778523, Blast_Score=277, Evalue=8e-76,
Organism=Escherichia coli, GI1790571, Length=468, Percent_Identity=23.5042735042735, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789256, Length=457, Percent_Identity=23.6323851203501, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788173, Length=246, Percent_Identity=26.0162601626016, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71984122, Length=444, Percent_Identity=35.1351351351351, Blast_Score=261, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI17556372, Length=422, Percent_Identity=32.2274881516588, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17551876, Length=455, Percent_Identity=27.9120879120879, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32566633, Length=288, Percent_Identity=25.3472222222222, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994340, Length=461, Percent_Identity=22.1258134490239, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17535925, Length=403, Percent_Identity=22.5806451612903, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17535927, Length=388, Percent_Identity=22.680412371134, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321807, Length=443, Percent_Identity=35.665914221219, Blast_Score=271, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6319872, Length=467, Percent_Identity=32.1199143468951, Blast_Score=229, Evalue=9e-61,
Organism=Saccharomyces cerevisiae, GI6323011, Length=461, Percent_Identity=30.3687635574837, Blast_Score=166, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6325153, Length=257, Percent_Identity=26.0700389105058, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19921528, Length=433, Percent_Identity=34.4110854503464, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI19922416, Length=453, Percent_Identity=30.9050772626932, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI17136276, Length=449, Percent_Identity=28.5077951002227, Blast_Score=165, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24640851, Length=463, Percent_Identity=23.3261339092873, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640849, Length=463, Percent_Identity=23.3261339092873, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_BACA2 (A7Z5Y7)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001421644.1
- ProteinModelPortal:   A7Z5Y7
- SMR:   A7Z5Y7
- STRING:   A7Z5Y7
- EnsemblBacteria:   EBBACT00000005725
- GeneID:   5462020
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_020510
- eggNOG:   COG0017
- GeneTree:   EBGT00050000000858
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- BioCyc:   BAMY326423:RBAM_020510-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 49108; Mature: 49108

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTINQVYKHTGEEVMIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEEDIFQIA
CCCHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEEEEHHHHHHHHHH
KSVTQETSLYVKGIVKEDERSPLGYELAVTSIEVIHEATDYPITPKEHGTEFLMDHRHLW
HHHHHHHHHHHEEEECCCCCCCCCEEHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHH
LRSKRQHAIMKIRNEIIRATYEFFNKEGFVKVDPPILTGSAPEGTTELFATKYFDEDAFL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCHHHHHHHHCCCHHHH
SQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLEVQEN
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCEEEEEECCCCCHHHH
YVAYIVQSVLEHCKIELNTLGRDTSKLEQIKAPFPRITYDKAIEFLKEKGFDDIEWGDDF
HHHHHHHHHHHHCEEEHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
GAPHETAIAESYDKPVFITHYPTSLKPFYMQPAKDRDDVVLCADLIAPEGYGEIIGGSER
CCCCHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCCH
VHDMDLLEERLKEHGLDSDAYKWYAELRQYGSVPHSGFGLGLERTVAWISGAPHVRETIP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHCCC
FPRLLNRLYP
HHHHHHHHCC
>Mature Secondary Structure
MKTTINQVYKHTGEEVMIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEEDIFQIA
CCCHHHHHHHCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEEEEHHHHHHHHHH
KSVTQETSLYVKGIVKEDERSPLGYELAVTSIEVIHEATDYPITPKEHGTEFLMDHRHLW
HHHHHHHHHHHEEEECCCCCCCCCEEHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHH
LRSKRQHAIMKIRNEIIRATYEFFNKEGFVKVDPPILTGSAPEGTTELFATKYFDEDAFL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCHHHHHHHHCCCHHHH
SQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLEVQEN
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCEEEEEECCCCCHHHH
YVAYIVQSVLEHCKIELNTLGRDTSKLEQIKAPFPRITYDKAIEFLKEKGFDDIEWGDDF
HHHHHHHHHHHHCEEEHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
GAPHETAIAESYDKPVFITHYPTSLKPFYMQPAKDRDDVVLCADLIAPEGYGEIIGGSER
CCCCHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCCH
VHDMDLLEERLKEHGLDSDAYKWYAELRQYGSVPHSGFGLGLERTVAWISGAPHVRETIP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHCCC
FPRLLNRLYP
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA