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The map label for this gene is yodS [H]

Identifier: 154686388

GI number: 154686388

Start: 2069391

End: 2070080

Strand: Reverse

Name: yodS [H]

Synonym: RBAM_019560

Alternate gene names: 154686388

Gene position: 2070080-2069391 (Counterclockwise)

Preceding gene: 154686389

Following gene: 154686387

Centisome position: 52.83

GC content: 49.71

Gene sequence:

>690_bases
ATGTCTATTTTTCATAAAAAAATCGATATTCATGAAGCAATTGCCGATGTCAAGGACGAATCTGTCATCATGTTCGGCGG
TTTTGGGGGAGTGGGTTCACCTCCGTCATTAATAGAAGCGATTTTGGAAAGCGGCGTTAAAGAGCTGACCGTCATCTGCA
ATGATGCCGGATTTCCGGAAATCGGCATCGGCCCGCTTATCGTTCATAAACGGGTAAAAAGGCTGATCGCTTCCCATATC
GGCTCAAATCCTGTCGCGGGCAGACAAATGACTGACGGAGCGCTTGAGGTGGAATTTTCGCCGCAAGGGACGCTTGCTGA
ACGGATTCGCGCAGGCGGAGCGGGGCTAGGCGGTATTTTAACTGATATCGGCATTGATAACGCAACCGTTTGTGAAAACA
AAGAAACCGTAACGATTGACGGAAAGTCCTATTTAGTTGAAAAAGCGCTGACTGCTGATTTCGCTTTTGTGTCTGCACAT
ACTGCTGATGAATTCGGGAATCTGACGTTTGACAAAACGGCGCGCAACATGAACCCTCTGATGGCTGCGGCGGCCGAAAG
AACATTTGCTGAGGCAGCAGAGATTGTGCCTGCCGGCGAACTTGACAGCGAGCATATTGTAACGCCGGGCGTTTTCGTGG
AGGGTGTCGTGCAAAGTGAAGGAGTGAAGTGGAGATGGGCTTGGGAATAG

Upstream 100 bases:

>100_bases
GCCGTTCACGATCTCATATGCCGAGCTGGATGAGCTGTCAGATCTATTTTCCCAGGCCGCAGAAGAAGTTGAAAAAATGA
TGAAGAAGGATTGAGCTGAT

Downstream 100 bases:

>100_bases
CGGAAAGAGAGAGTATCGCGAGGCGGGCCGCCAGTGAAGTTACCTCAGGTATGATTGTCAACCTGGGGATCGGCATTCCT
TCTTTAGTGCCGAACTTTCT

Product: YodS

Products: Acetate; Butanoyl-CoA [C]

Alternate protein names: Probable CoA-transferase subunit alpha [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSIFHKKIDIHEAIADVKDESVIMFGGFGGVGSPPSLIEAILESGVKELTVICNDAGFPEIGIGPLIVHKRVKRLIASHI
GSNPVAGRQMTDGALEVEFSPQGTLAERIRAGGAGLGGILTDIGIDNATVCENKETVTIDGKSYLVEKALTADFAFVSAH
TADEFGNLTFDKTARNMNPLMAAAAERTFAEAAEIVPAGELDSEHIVTPGVFVEGVVQSEGVKWRWAWE

Sequences:

>Translated_229_residues
MSIFHKKIDIHEAIADVKDESVIMFGGFGGVGSPPSLIEAILESGVKELTVICNDAGFPEIGIGPLIVHKRVKRLIASHI
GSNPVAGRQMTDGALEVEFSPQGTLAERIRAGGAGLGGILTDIGIDNATVCENKETVTIDGKSYLVEKALTADFAFVSAH
TADEFGNLTFDKTARNMNPLMAAAAERTFAEAAEIVPAGELDSEHIVTPGVFVEGVVQSEGVKWRWAWE
>Mature_228_residues
SIFHKKIDIHEAIADVKDESVIMFGGFGGVGSPPSLIEAILESGVKELTVICNDAGFPEIGIGPLIVHKRVKRLIASHIG
SNPVAGRQMTDGALEVEFSPQGTLAERIRAGGAGLGGILTDIGIDNATVCENKETVTIDGKSYLVEKALTADFAFVSAHT
ADEFGNLTFDKTARNMNPLMAAAAERTFAEAAEIVPAGELDSEHIVTPGVFVEGVVQSEGVKWRWAWE

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=234, Percent_Identity=39.7435897435897, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI11545841, Length=234, Percent_Identity=36.3247863247863, Blast_Score=147, Evalue=5e-36,
Organism=Escherichia coli, GI1788551, Length=218, Percent_Identity=50.4587155963303, Blast_Score=224, Evalue=4e-60,
Organism=Escherichia coli, GI1787985, Length=233, Percent_Identity=26.6094420600858, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17531517, Length=231, Percent_Identity=35.4978354978355, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21358325, Length=242, Percent_Identity=40.495867768595, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24655794, Length=242, Percent_Identity=40.495867768595, Blast_Score=171, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: 2.8.3.8 [C]

Molecular weight: Translated: 24317; Mature: 24186

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFHKKIDIHEAIADVKDESVIMFGGFGGVGSPPSLIEAILESGVKELTVICNDAGFPE
CCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHEEEEEECCCCCCC
IGIGPLIVHKRVKRLIASHIGSNPVAGRQMTDGALEVEFSPQGTLAERIRAGGAGLGGIL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEECCCCHHHHHHHCCCCCCCHHH
TDIGIDNATVCENKETVTIDGKSYLVEKALTADFAFVSAHTADEFGNLTFDKTARNMNPL
HHCCCCCCEEECCCCEEEECCHHHHHHHHHHHHHHEEECCCHHHHCCCCHHHHHCCCCHH
MAAAAERTFAEAAEIVPAGELDSEHIVTPGVFVEGVVQSEGVKWRWAWE
HHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure 
SIFHKKIDIHEAIADVKDESVIMFGGFGGVGSPPSLIEAILESGVKELTVICNDAGFPE
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHEEEEEECCCCCCC
IGIGPLIVHKRVKRLIASHIGSNPVAGRQMTDGALEVEFSPQGTLAERIRAGGAGLGGIL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEECCCCHHHHHHHCCCCCCCHHH
TDIGIDNATVCENKETVTIDGKSYLVEKALTADFAFVSAHTADEFGNLTFDKTARNMNPL
HHCCCCCCEEECCCCEEEECCHHHHHHHHHHHHHHEEECCCHHHHCCCCHHHHHCCCCHH
MAAAAERTFAEAAEIVPAGELDSEHIVTPGVFVEGVVQSEGVKWRWAWE
HHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Butyrate [C]

Specific reaction: Acetyl-CoA + Butyrate (n-C4:0) --> Acetate + Butanoyl-CoA [C]

General reaction: Coenzyme A transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]