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The map label for this gene is deoD [H]

Identifier: 154686374

GI number: 154686374

Start: 2060651

End: 2061349

Strand: Reverse

Name: deoD [H]

Synonym: RBAM_019420

Alternate gene names: 154686374

Gene position: 2061349-2060651 (Counterclockwise)

Preceding gene: 154686376

Following gene: 154686373

Centisome position: 52.6

GC content: 44.64

Gene sequence:

>699_bases
ATGAGTGTACATATAAACGCAGAAAAAGGCCAAATTGCGGATACAGTGCTTTTGCCGGGAGATCCGCTCCGAGCGAAATT
TATTGCGGAAACTTATCTTGAAAATGTGGAATGCTATAATGAAGTCAGAGGAATGTACGGATTTACGGGTACATATAACG
GCAAAAAAGTATCAGTCCAAGGCACCGGCATGGGTGTTCCGTCTATCTCTATTTATGTGAATGAACTGATTCAAAGCTAT
GATGTTCAAAACTTAATCAGAGTCGGCTCATGCGGAGCCATCCGTAATGACGTGAAGGTGCGTGACGTGATTTTGGCTAT
GACGTCTTCAACTGATTCACAGATGAACCGTGTCGCCTTCGGCAGTGTAGATTATGCTCCTTGCGCAGACTTCGAACTGC
TTAATAAAGCGTACCAGGAAGCGCAAAAAAACAATCTTCCCGTAGCGGTCGGAAGCGTATTCACTGCCGATCAGTTTTAC
AATGAAGACTCCCAAATCGAAAAGCTTGCCAGATACGGCGTTCTCGGCGTAGAGATGGAAACGACTGCTTTATATACGCT
TGCCGCTAAATACGGCAAAAAAGCGCTGTCTATCCTGACTGTAAGCGATCACGTATTAACGGGAGAAGAAACAACGGCAG
AAGAGCGTCAAACGACTTTTCATGATATGATTAAACTGGCGCTGCATACTGTATCGTAA

Upstream 100 bases:

>100_bases
CATATTCTGCCCAAGATCGCCCCAGTCATGCTGATGATTGTCTCTTACCGTTATTCAGTGTACAATGGGTGGGAGTTTGA
ATAGGCAGGAGGAAAAGGAA

Downstream 100 bases:

>100_bases
ACTTGAGATGAGGGTTATGCTGATTAAAGCAGCCCTCTTCTTTATGCATCGCCCTGATTCAAAAAAAGAAAGGTAAGTGT
AAAATGAAGAAATCCACTAA

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP; Purine nucleoside phosphorylase II; PU-NPase II [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSVHINAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRGMYGFTGTYNGKKVSVQGTGMGVPSISIYVNELIQSY
DVQNLIRVGSCGAIRNDVKVRDVILAMTSSTDSQMNRVAFGSVDYAPCADFELLNKAYQEAQKNNLPVAVGSVFTADQFY
NEDSQIEKLARYGVLGVEMETTALYTLAAKYGKKALSILTVSDHVLTGEETTAEERQTTFHDMIKLALHTVS

Sequences:

>Translated_232_residues
MSVHINAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRGMYGFTGTYNGKKVSVQGTGMGVPSISIYVNELIQSY
DVQNLIRVGSCGAIRNDVKVRDVILAMTSSTDSQMNRVAFGSVDYAPCADFELLNKAYQEAQKNNLPVAVGSVFTADQFY
NEDSQIEKLARYGVLGVEMETTALYTLAAKYGKKALSILTVSDHVLTGEETTAEERQTTFHDMIKLALHTVS
>Mature_231_residues
SVHINAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRGMYGFTGTYNGKKVSVQGTGMGVPSISIYVNELIQSYD
VQNLIRVGSCGAIRNDVKVRDVILAMTSSTDSQMNRVAFGSVDYAPCADFELLNKAYQEAQKNNLPVAVGSVFTADQFYN
EDSQIEKLARYGVLGVEMETTALYTLAAKYGKKALSILTVSDHVLTGEETTAEERQTTFHDMIKLALHTVS

Specific function: Cleavage of adenosine and its derivatives [H]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=229, Percent_Identity=55.0218340611354, Blast_Score=270, Evalue=9e-74,
Organism=Escherichia coli, GI1790265, Length=200, Percent_Identity=29.5, Blast_Score=77, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25459; Mature: 25328

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHINAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRGMYGFTGTYNGKKVSVQ
CEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
GTGMGVPSISIYVNELIQSYDVQNLIRVGSCGAIRNDVKVRDVILAMTSSTDSQMNRVAF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEHEEEEEECCCCHHHHHEEE
GSVDYAPCADFELLNKAYQEAQKNNLPVAVGSVFTADQFYNEDSQIEKLARYGVLGVEME
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCEEHHHHHCCCHHHHHHHHHHCEEEEEEH
TTALYTLAAKYGKKALSILTVSDHVLTGEETTAEERQTTFHDMIKLALHTVS
HHHHHHHHHHHCCCEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVHINAEKGQIADTVLLPGDPLRAKFIAETYLENVECYNEVRGMYGFTGTYNGKKVSVQ
EEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
GTGMGVPSISIYVNELIQSYDVQNLIRVGSCGAIRNDVKVRDVILAMTSSTDSQMNRVAF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEHEEEEEECCCCHHHHHEEE
GSVDYAPCADFELLNKAYQEAQKNNLPVAVGSVFTADQFYNEDSQIEKLARYGVLGVEME
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCEEHHHHHCCCHHHHHHHHHHCEEEEEEH
TTALYTLAAKYGKKALSILTVSDHVLTGEETTAEERQTTFHDMIKLALHTVS
HHHHHHHHHHHCCCEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]