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The map label for this gene is yhdP [H]

Identifier: 154685412

GI number: 154685412

Start: 957519

End: 958853

Strand: Reverse

Name: yhdP [H]

Synonym: RBAM_009780

Alternate gene names: 154685412

Gene position: 958853-957519 (Counterclockwise)

Preceding gene: 154685413

Following gene: 154685410

Centisome position: 24.47

GC content: 44.57

Gene sequence:

>1335_bases
TTGGACATTGTGAATTTGATTTTAGTCGCGGTTTTAATCGCGCTGACGGCATTTTTCGTAGCATCTGAGTTTGCGATAAT
CAGAATCAGAGGCTCACGGGTTGACCAGCTTATAGCAGAAGGAAATAAAGCCGCAATCGGTGTCAAAAAAGTGACCACGC
ATTTAGATGAGTATTTATCGGCGTGCCAGCTCGGCATAACATTGACTTCCATCGGTCTTGGTGTCTTAGGCGAATCAACG
ATTGAACGCTTGCTTCATCCGCTTTTCACAAAGATAAACGTACCAAGCTCATTATCGCATATTATTTCATTTATTCTCGC
CTATGCGATCATTACATTCTTACACGTGGTCGTGGGAGAGTTGGCGCCGAAAACAGTCGCCATCCAGAAAGCGGAAGCCG
TTTCAATGCTGTTTTCGAAACCGCTCATTTGGTTTTACCGCATCATGTTCCCGTTTATCTGGCTTCTGAACAACTCCGCC
CGTCTTTTAACGAAGACGTTCGGTCTGGAGACGGTGTCTGAAAATGAGCTTGCCCACTCTGAAGAAGAGCTGCGCATCAT
TTTATCGGAAAGCTATAAAAGCGGTGAAATCAACCAGTCTGAATTTAAATACGTGAACAAAATCTTTGAATTTGACGACA
GACTTGCAAAAGAAATCATGATTCCGCGTACGGAAATCGTCAGTCTGCCGCATGATATCAAAATTTCTGAAATGATGGAC
ATCATTCAGATTGAAAAATATACCCGGTACCCTGTCGAAGAGGGTGACAAAGATAATATTATCGGCGTTATTAACATTAA
AGAAGTGCTGACCGCCTGCATCAGCGGCGAAGTATCAGTCGACTCGCCGATTACCGATTTTGTCAATCCGATCATCCATG
TGATTGAGTCGGCACCGATTCACGATCTGCTTGTAAAAATGCAGAAGGAACGGGTTCATATGGCGATTCTGTCGGATGAA
TACGGCGGAACCGCGGGGCTTGTCACCGTTGAAGACATTATTGAAGAAATCGTCGGGGAAATCCGTGATGAATTTGATAT
CGATGAAATCAACGAAATCCGCAAACTCGGCGACGGCCATTACATGCTTGACGGCAAGGTCCTGATTGATCAAGTGAACG
AACTCCTCGGCATCCATTTAGAAAATGACGAGGTCGACACCATTGGCGGCTGGTTCCTTACCCAGAAATACGACGTCGAA
CAATACGACTCGATTATCGAAGAAGGCTGTGAATTTATCATTAATGAAATTGACGGCCACCACGTCGCATATATCGAAGT
GAAAAAACTGGCGTTTGATGAACTGCTGGAAACCGCCGAACAAAAAGAAGCATAA

Upstream 100 bases:

>100_bases
CTTGCAGTGCTTCAATCATTTATGCTGCTGTTAAGTTAAACCATTATCTTACTAACAGGAGGTGTTACCTTCATCTTCCC
AAAAGGAGTGAAGGTTCTAA

Downstream 100 bases:

>100_bases
CAAAAAAGCTTGCGCGTCTGATACAGACGGCAAGCTTTTTTTCATTTACAGTTGTTCAAGTTTTTTCTCAAGCTCTTTAA
TTCTGGCATTCAGCTCTTCT

Product: TlyC family hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MDIVNLILVAVLIALTAFFVASEFAIIRIRGSRVDQLIAEGNKAAIGVKKVTTHLDEYLSACQLGITLTSIGLGVLGEST
IERLLHPLFTKINVPSSLSHIISFILAYAIITFLHVVVGELAPKTVAIQKAEAVSMLFSKPLIWFYRIMFPFIWLLNNSA
RLLTKTFGLETVSENELAHSEEELRIILSESYKSGEINQSEFKYVNKIFEFDDRLAKEIMIPRTEIVSLPHDIKISEMMD
IIQIEKYTRYPVEEGDKDNIIGVINIKEVLTACISGEVSVDSPITDFVNPIIHVIESAPIHDLLVKMQKERVHMAILSDE
YGGTAGLVTVEDIIEEIVGEIRDEFDIDEINEIRKLGDGHYMLDGKVLIDQVNELLGIHLENDEVDTIGGWFLTQKYDVE
QYDSIIEEGCEFIINEIDGHHVAYIEVKKLAFDELLETAEQKEA

Sequences:

>Translated_444_residues
MDIVNLILVAVLIALTAFFVASEFAIIRIRGSRVDQLIAEGNKAAIGVKKVTTHLDEYLSACQLGITLTSIGLGVLGEST
IERLLHPLFTKINVPSSLSHIISFILAYAIITFLHVVVGELAPKTVAIQKAEAVSMLFSKPLIWFYRIMFPFIWLLNNSA
RLLTKTFGLETVSENELAHSEEELRIILSESYKSGEINQSEFKYVNKIFEFDDRLAKEIMIPRTEIVSLPHDIKISEMMD
IIQIEKYTRYPVEEGDKDNIIGVINIKEVLTACISGEVSVDSPITDFVNPIIHVIESAPIHDLLVKMQKERVHMAILSDE
YGGTAGLVTVEDIIEEIVGEIRDEFDIDEINEIRKLGDGHYMLDGKVLIDQVNELLGIHLENDEVDTIGGWFLTQKYDVE
QYDSIIEEGCEFIINEIDGHHVAYIEVKKLAFDELLETAEQKEA
>Mature_444_residues
MDIVNLILVAVLIALTAFFVASEFAIIRIRGSRVDQLIAEGNKAAIGVKKVTTHLDEYLSACQLGITLTSIGLGVLGEST
IERLLHPLFTKINVPSSLSHIISFILAYAIITFLHVVVGELAPKTVAIQKAEAVSMLFSKPLIWFYRIMFPFIWLLNNSA
RLLTKTFGLETVSENELAHSEEELRIILSESYKSGEINQSEFKYVNKIFEFDDRLAKEIMIPRTEIVSLPHDIKISEMMD
IIQIEKYTRYPVEEGDKDNIIGVINIKEVLTACISGEVSVDSPITDFVNPIIHVIESAPIHDLLVKMQKERVHMAILSDE
YGGTAGLVTVEDIIEEIVGEIRDEFDIDEINEIRKLGDGHYMLDGKVLIDQVNELLGIHLENDEVDTIGGWFLTQKYDVE
QYDSIIEEGCEFIINEIDGHHVAYIEVKKLAFDELLETAEQKEA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=403, Percent_Identity=48.8833746898263, Blast_Score=408, Evalue=1e-114,
Organism=Escherichia coli, GI1790664, Length=448, Percent_Identity=22.3214285714286, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI145693175, Length=402, Percent_Identity=25.8706467661692, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786879, Length=277, Percent_Identity=28.5198555956679, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788119, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082033, Length=250, Percent_Identity=23.2, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17539402, Length=264, Percent_Identity=26.1363636363636, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49975; Mature: 49975

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIVNLILVAVLIALTAFFVASEFAIIRIRGSRVDQLIAEGNKAAIGVKKVTTHLDEYLS
CCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHCCCCCEEHHHHHHHHHHHHHH
ACQLGITLTSIGLGVLGESTIERLLHPLFTKINVPSSLSHIISFILAYAIITFLHVVVGE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTVAIQKAEAVSMLFSKPLIWFYRIMFPFIWLLNNSARLLTKTFGLETVSENELAHS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHCC
EEELRIILSESYKSGEINQSEFKYVNKIFEFDDRLAKEIMIPRTEIVSLPHDIKISEMMD
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHH
IIQIEKYTRYPVEEGDKDNIIGVINIKEVLTACISGEVSVDSPITDFVNPIIHVIESAPI
HHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCH
HDLLVKMQKERVHMAILSDEYGGTAGLVTVEDIIEEIVGEIRDEFDIDEINEIRKLGDGH
HHHHHHHHHHHHHEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
YMLDGKVLIDQVNELLGIHLENDEVDTIGGWFLTQKYDVEQYDSIIEEGCEFIINEIDGH
EEECCHHHHHHHHHHHCEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCC
HVAYIEVKKLAFDELLETAEQKEA
EEEEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIVNLILVAVLIALTAFFVASEFAIIRIRGSRVDQLIAEGNKAAIGVKKVTTHLDEYLS
CCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHCCCCCEEHHHHHHHHHHHHHH
ACQLGITLTSIGLGVLGESTIERLLHPLFTKINVPSSLSHIISFILAYAIITFLHVVVGE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTVAIQKAEAVSMLFSKPLIWFYRIMFPFIWLLNNSARLLTKTFGLETVSENELAHS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHCC
EEELRIILSESYKSGEINQSEFKYVNKIFEFDDRLAKEIMIPRTEIVSLPHDIKISEMMD
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHH
IIQIEKYTRYPVEEGDKDNIIGVINIKEVLTACISGEVSVDSPITDFVNPIIHVIESAPI
HHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCH
HDLLVKMQKERVHMAILSDEYGGTAGLVTVEDIIEEIVGEIRDEFDIDEINEIRKLGDGH
HHHHHHHHHHHHHEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
YMLDGKVLIDQVNELLGIHLENDEVDTIGGWFLTQKYDVEQYDSIIEEGCEFIINEIDGH
EEECCHHHHHHHHHHHCEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCC
HVAYIEVKKLAFDELLETAEQKEA
EEEEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]