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The map label for this gene is katA [H]

Identifier: 154685344

GI number: 154685344

Start: 889388

End: 890833

Strand: Reverse

Name: katA [H]

Synonym: RBAM_009090

Alternate gene names: 154685344

Gene position: 890833-889388 (Counterclockwise)

Preceding gene: 154685351

Following gene: 154685342

Centisome position: 22.73

GC content: 49.86

Gene sequence:

>1446_bases
ATGAGTTCAAATAAATTGACAACCAGCTGGGGCGCTCCTGTCGGAGATAACCAAAACTCAATGACGGCCGGCGATCGCGG
TCCTGCTTTAATACAAGACGTCCATCTGCTTGAGAAATTGGCGCACTTTAACAGAGAACGCGTTCCCGAGCGTGTCGTTC
ACGCAAAAGGCGCGGGCGCACACGGTTATTTTGAAGTCACAAATGACGTTACAAAATATACGAAAGCCGCATTTCTGTCA
GAAGTCGGTAAACGCACGCCGCTCTTCATCCGTTTCTCAACCGTTGCGGGCGAACTGGGCTCTAGTGACACAGTGCGCGA
CCCGCGCGGATTTGCCGTTAAGTTTTATACAGAAGAAGGAAACTACGACATCGTCGGAAACAATACACCCGTGTTCTTCA
TCCGCGATGCCATCAAGTTCCCTGACTTTATCCATACACAAAAAAGAGATCCGAGAACACATCTGAAAAACCCGACGGCC
GTTTGGGATTTCTGGTCTCTGTCACCGGAATCCCTGCACCAGGTCACCATTCTGATGTCAGACCGGGGCATTCCGGCGAC
TCTTCGCCATATGCACGGATTCGGAAGCCATACATTTAAATGGACAAATGATAAAGGCGAAGGCGTCTGGATCAAATATC
ACTTTAAAACAGAGCAAGGCGTGAAAAACCTTGATGTTAATACAGCCGCAAAAATCGCGGGCGAAAATCCCGATTACCAT
ACGGAAGATTTGTTCAACGCGATTGAAAACGGCGATTTCCCCGCATGGAAATTATATGTTCAAATCATGCCGTTAGAAGA
CGCAAACACATATCGCTTTGATCCGTTTGACGTCACAAAAGTATGGTCTCAAAAAGATTATCCGCTGATCGAAGTCGGCC
GCATGGTTCTGAACCGCAATCCGGAAAATTACTTTGCGGAAGTAGAACAGGCGACGTTCTCTCCCGGCACATTAGTCCCC
GGCGTCGACGTCTCACCTGACAAAATGCTTCAAGGCCGGTTGTTCGCATACCATGACGCGCATCGCTACCGTGTCGGCGC
GAACCATCAGGCGCTGCCGATCAACCGTTCCCGCAATGAAGTGAAAAACTATCAGCGTGACGGACAAATGCGTTTTGATG
ATAACGGCGGCCGCTCCGTCTATTACGAGCCTAACAGCTTCGGCGGCCCGAAAGAGTCACCTGAAGATAAACAGGCGGCA
TATCCTGTATCAGGTTTCGCTGACAGTGTAAGCTATAATCATCATGATCATTACACACAAGCCGGCGACCTGTACCGCCT
GATGAGCGAAGAAGAGCGCGCGCGCCTTGTCGCCAATATCGTCAGTGCGATGAAACCTGTGGAAAAAGAAGAAATTAAGC
TGCGCCAGATCGGCCACTTCTACAAAGCTGATCCTGAATACGGCAGACGCGTTGCCGAAGGACTCGGACTGCCATCACCA
AAATAA

Upstream 100 bases:

>100_bases
TTCGATAATAAAAATAATTATTTTATAATCATTATAAAATAACATTGACTTTTTAATGATAGGTGATATTATGTTTTTAT
AAATCTAAAGAGGTGATCAC

Downstream 100 bases:

>100_bases
CATCAAAAAACCTGCCGGTCTGCCCGGCAGGTTTTTCCTGTTTATTATCAATAAAACCGTTTTTTTCTCAATTACCGGAT
GAGAAGCTTTAAACTCCTTT

Product: KatA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSSNKLTTSWGAPVGDNQNSMTAGDRGPALIQDVHLLEKLAHFNRERVPERVVHAKGAGAHGYFEVTNDVTKYTKAAFLS
EVGKRTPLFIRFSTVAGELGSSDTVRDPRGFAVKFYTEEGNYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPRTHLKNPTA
VWDFWSLSPESLHQVTILMSDRGIPATLRHMHGFGSHTFKWTNDKGEGVWIKYHFKTEQGVKNLDVNTAAKIAGENPDYH
TEDLFNAIENGDFPAWKLYVQIMPLEDANTYRFDPFDVTKVWSQKDYPLIEVGRMVLNRNPENYFAEVEQATFSPGTLVP
GVDVSPDKMLQGRLFAYHDAHRYRVGANHQALPINRSRNEVKNYQRDGQMRFDDNGGRSVYYEPNSFGGPKESPEDKQAA
YPVSGFADSVSYNHHDHYTQAGDLYRLMSEEERARLVANIVSAMKPVEKEEIKLRQIGHFYKADPEYGRRVAEGLGLPSP
K

Sequences:

>Translated_481_residues
MSSNKLTTSWGAPVGDNQNSMTAGDRGPALIQDVHLLEKLAHFNRERVPERVVHAKGAGAHGYFEVTNDVTKYTKAAFLS
EVGKRTPLFIRFSTVAGELGSSDTVRDPRGFAVKFYTEEGNYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPRTHLKNPTA
VWDFWSLSPESLHQVTILMSDRGIPATLRHMHGFGSHTFKWTNDKGEGVWIKYHFKTEQGVKNLDVNTAAKIAGENPDYH
TEDLFNAIENGDFPAWKLYVQIMPLEDANTYRFDPFDVTKVWSQKDYPLIEVGRMVLNRNPENYFAEVEQATFSPGTLVP
GVDVSPDKMLQGRLFAYHDAHRYRVGANHQALPINRSRNEVKNYQRDGQMRFDDNGGRSVYYEPNSFGGPKESPEDKQAA
YPVSGFADSVSYNHHDHYTQAGDLYRLMSEEERARLVANIVSAMKPVEKEEIKLRQIGHFYKADPEYGRRVAEGLGLPSP
K
>Mature_480_residues
SSNKLTTSWGAPVGDNQNSMTAGDRGPALIQDVHLLEKLAHFNRERVPERVVHAKGAGAHGYFEVTNDVTKYTKAAFLSE
VGKRTPLFIRFSTVAGELGSSDTVRDPRGFAVKFYTEEGNYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPRTHLKNPTAV
WDFWSLSPESLHQVTILMSDRGIPATLRHMHGFGSHTFKWTNDKGEGVWIKYHFKTEQGVKNLDVNTAAKIAGENPDYHT
EDLFNAIENGDFPAWKLYVQIMPLEDANTYRFDPFDVTKVWSQKDYPLIEVGRMVLNRNPENYFAEVEQATFSPGTLVPG
VDVSPDKMLQGRLFAYHDAHRYRVGANHQALPINRSRNEVKNYQRDGQMRFDDNGGRSVYYEPNSFGGPKESPEDKQAAY
PVSGFADSVSYNHHDHYTQAGDLYRLMSEEERARLVANIVSAMKPVEKEEIKLRQIGHFYKADPEYGRRVAEGLGLPSPK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=475, Percent_Identity=56.2105263157895, Blast_Score=560, Evalue=1e-159,
Organism=Escherichia coli, GI48994891, Length=398, Percent_Identity=49.748743718593, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71998444, Length=468, Percent_Identity=54.9145299145299, Blast_Score=536, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI25147792, Length=472, Percent_Identity=53.8135593220339, Blast_Score=526, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI25151141, Length=472, Percent_Identity=53.6016949152542, Blast_Score=525, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6320462, Length=385, Percent_Identity=52.4675324675325, Blast_Score=414, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6321525, Length=507, Percent_Identity=39.0532544378698, Blast_Score=362, Evalue=1e-101,
Organism=Drosophila melanogaster, GI17981717, Length=484, Percent_Identity=53.7190082644628, Blast_Score=536, Evalue=1e-153,
Organism=Drosophila melanogaster, GI19920968, Length=476, Percent_Identity=47.6890756302521, Blast_Score=479, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54537; Mature: 54406

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNKLTTSWGAPVGDNQNSMTAGDRGPALIQDVHLLEKLAHFNRERVPERVVHAKGAGA
CCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCC
HGYFEVTNDVTKYTKAAFLSEVGKRTPLFIRFSTVAGELGSSDTVRDPRGFAVKFYTEEG
CCEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCCCCCCCCCCCEEEEEEECC
NYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPRTHLKNPTAVWDFWSLSPESLHQVTILMS
CEEEECCCCCEEEEECCCCCCHHHHCCCCCCHHHCCCCCEEEEECCCCHHHHEEEEEEEE
DRGIPATLRHMHGFGSHTFKWTNDKGEGVWIKYHFKTEQGVKNLDVNTAAKIAGENPDYH
CCCCCHHHHHHHCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCHHHHCCCCCCCCC
TEDLFNAIENGDFPAWKLYVQIMPLEDANTYRFDPFDVTKVWSQKDYPLIEVGRMVLNRN
HHHHHHHHHCCCCCEEEEEEEEEECCCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHCCC
PENYFAEVEQATFSPGTLVPGVDVSPDKMLQGRLFAYHDAHRYRVGANHQALPINRSRNE
CHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCHHH
VKNYQRDGQMRFDDNGGRSVYYEPNSFGGPKESPEDKQAAYPVSGFADSVSYNHHDHYTQ
HHHHHHCCCEEEECCCCCEEEECCCCCCCCCCCCCCHHCCCCCCCCHHCCCCCCCCCCCC
AGDLYRLMSEEERARLVANIVSAMKPVEKEEIKLRQIGHFYKADPEYGRRVAEGLGLPSP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
K
C
>Mature Secondary Structure 
SSNKLTTSWGAPVGDNQNSMTAGDRGPALIQDVHLLEKLAHFNRERVPERVVHAKGAGA
CCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCC
HGYFEVTNDVTKYTKAAFLSEVGKRTPLFIRFSTVAGELGSSDTVRDPRGFAVKFYTEEG
CCEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCCCCCCCCCCCCCEEEEEEECC
NYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPRTHLKNPTAVWDFWSLSPESLHQVTILMS
CEEEECCCCCEEEEECCCCCCHHHHCCCCCCHHHCCCCCEEEEECCCCHHHHEEEEEEEE
DRGIPATLRHMHGFGSHTFKWTNDKGEGVWIKYHFKTEQGVKNLDVNTAAKIAGENPDYH
CCCCCHHHHHHHCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCHHHHCCCCCCCCC
TEDLFNAIENGDFPAWKLYVQIMPLEDANTYRFDPFDVTKVWSQKDYPLIEVGRMVLNRN
HHHHHHHHHCCCCCEEEEEEEEEECCCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHCCC
PENYFAEVEQATFSPGTLVPGVDVSPDKMLQGRLFAYHDAHRYRVGANHQALPINRSRNE
CHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCHHH
VKNYQRDGQMRFDDNGGRSVYYEPNSFGGPKESPEDKQAAYPVSGFADSVSYNHHDHYTQ
HHHHHHCCCEEEECCCCCEEEECCCCCCCCCCCCCCHHCCCCCCCCHHCCCCCCCCCCCC
AGDLYRLMSEEERARLVANIVSAMKPVEKEEIKLRQIGHFYKADPEYGRRVAEGLGLPSP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1756979; 9202460; 9384377; 8180695; 10658653 [H]