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The map label for this gene is yfnC [H]

Identifier: 154685212

GI number: 154685212

Start: 743808

End: 745037

Strand: Reverse

Name: yfnC [H]

Synonym: RBAM_007570

Alternate gene names: 154685212

Gene position: 745037-743808 (Counterclockwise)

Preceding gene: 154685213

Following gene: 154685193

Centisome position: 19.01

GC content: 51.87

Gene sequence:

>1230_bases
TTGGCAATTGCCGCCCCGCTTAAAGAAAAACCTGTCCATCGTCCCGAGACAACCATGTATTCTATTTTGTTCATTATCGG
GATTTGTCATCTGCTGAACGATTCACTGCAAGCGGTGATTCCGGCGATGTTTCCGATATTGGAACGTTCCATGAATCTTA
CATTTACGCAGCTCGGAATTATCGCCTTTACGCTGAATATGGTGTCTTCCGTGATGCAGCCCGTCATCGGCTGGTATACG
GATAAACGCCCGATGCCGTATGCCTTGCCGCTCGGACTCACCGCAAGCATGCTCGGCATTTTAGGTCTGGCGTTCGCCCC
GTCTTTTCTGACGATTTTATGCTGTGTCTTTTTTATCGGCCTTGGCTCCGCCGTCTTTCATCCTGAAGGATCGCGTGTCG
CCTACATGGCCGCCGGCGAAAAGCGCGGGTTGGCGCAATCGATTTACCAAGTCGGAGGGAATACCGGCCAGGCGATGGCG
CCCTTGATTACCGCGCTGATTCTCGTTCCGCTCGGTCAATTCGGCTCTGTCTGGTTTACGCTAGTCGCCGCAATCGCTGT
TCTGTTTCTCATTTATATCGCCAAATGGTATAAAGGCCGCCTTATTCATTTGCGCGCCGTAAGTAAAAAATCACCGGCCT
CCGCTGTGCAGACCGTGATTACAAAACCGATTATTCTCGCCCTTATCATGATTATCTTCTTAATTTTCGCGCGCTCCTGG
TATGTGAGCGCGATCGGCAACTTTTATACGTTCTATGCGATGAATGCCTATCATGTCAGCATTCAGCAGGCACAGAGCTA
CATCTTCGTCTTTTTATTTTTCGGAGCTGTCGGAACGTTTCTCGGCGGGCCGCTTGCAGACCGTTTCGGAAAGCGGAACG
TCATCATCGTTTCGATGATAGCATCGGCTCCATTGACAATTTTCCTTCCGTTTGCGGGGCCTGTCATCGCCTATGGCGTA
CTGGCGCTGATCGGTGTTGTTCTGATGTCCAGCTTCTCCGTGACGGTTGTCTACGCGCAGGAGCTTGTTCCAGGCAAAAT
CGGAACGATGTCAGGGCTTACGGTCGGGCTCGCCTTCGGAATGGGCGCGATCGGAGCCGTTGCGCTCGGAGCTCTTATTG
ATTCAGCGGGATTGACGCCGACTATGACTGCCGTCGCCTTTCTGCCCGTTTTAGGTCTGCTCGCCTTTGTCCTGCCGAGC
GACAAAACATTAAAAGAATGGCATTCATAA

Upstream 100 bases:

>100_bases
TCTGTTTGAGAAAGAAGAGCCTTTTTTGCACTTGATCATTCATTCACCTTATGAATAATATGGTGTATGCTTCGTTTACA
TAAAAAGGAGGAGAATCACT

Downstream 100 bases:

>100_bases
AAATAATCCCTGCCTTTTCGGCAGGGATTTTATGTTTCAACCGTATAAAAATGAGTGTCAGGAACCGCATATTTCGGAAT
AAACCCGTCTCTGAAATCAG

Product: YfnC

Products: fosmidomycin [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MAIAAPLKEKPVHRPETTMYSILFIIGICHLLNDSLQAVIPAMFPILERSMNLTFTQLGIIAFTLNMVSSVMQPVIGWYT
DKRPMPYALPLGLTASMLGILGLAFAPSFLTILCCVFFIGLGSAVFHPEGSRVAYMAAGEKRGLAQSIYQVGGNTGQAMA
PLITALILVPLGQFGSVWFTLVAAIAVLFLIYIAKWYKGRLIHLRAVSKKSPASAVQTVITKPIILALIMIIFLIFARSW
YVSAIGNFYTFYAMNAYHVSIQQAQSYIFVFLFFGAVGTFLGGPLADRFGKRNVIIVSMIASAPLTIFLPFAGPVIAYGV
LALIGVVLMSSFSVTVVYAQELVPGKIGTMSGLTVGLAFGMGAIGAVALGALIDSAGLTPTMTAVAFLPVLGLLAFVLPS
DKTLKEWHS

Sequences:

>Translated_409_residues
MAIAAPLKEKPVHRPETTMYSILFIIGICHLLNDSLQAVIPAMFPILERSMNLTFTQLGIIAFTLNMVSSVMQPVIGWYT
DKRPMPYALPLGLTASMLGILGLAFAPSFLTILCCVFFIGLGSAVFHPEGSRVAYMAAGEKRGLAQSIYQVGGNTGQAMA
PLITALILVPLGQFGSVWFTLVAAIAVLFLIYIAKWYKGRLIHLRAVSKKSPASAVQTVITKPIILALIMIIFLIFARSW
YVSAIGNFYTFYAMNAYHVSIQQAQSYIFVFLFFGAVGTFLGGPLADRFGKRNVIIVSMIASAPLTIFLPFAGPVIAYGV
LALIGVVLMSSFSVTVVYAQELVPGKIGTMSGLTVGLAFGMGAIGAVALGALIDSAGLTPTMTAVAFLPVLGLLAFVLPS
DKTLKEWHS
>Mature_408_residues
AIAAPLKEKPVHRPETTMYSILFIIGICHLLNDSLQAVIPAMFPILERSMNLTFTQLGIIAFTLNMVSSVMQPVIGWYTD
KRPMPYALPLGLTASMLGILGLAFAPSFLTILCCVFFIGLGSAVFHPEGSRVAYMAAGEKRGLAQSIYQVGGNTGQAMAP
LITALILVPLGQFGSVWFTLVAAIAVLFLIYIAKWYKGRLIHLRAVSKKSPASAVQTVITKPIILALIMIIFLIFARSWY
VSAIGNFYTFYAMNAYHVSIQQAQSYIFVFLFFGAVGTFLGGPLADRFGKRNVIIVSMIASAPLTIFLPFAGPVIAYGVL
ALIGVVLMSSFSVTVVYAQELVPGKIGTMSGLTVGLAFGMGAIGAVALGALIDSAGLTPTMTAVAFLPVLGLLAFVLPSD
KTLKEWHS

Specific function: Confers The Resistance Against Fosmidomycin. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786686, Length=386, Percent_Identity=43.7823834196891, Blast_Score=299, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43791; Mature: 43660

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIAAPLKEKPVHRPETTMYSILFIIGICHLLNDSLQAVIPAMFPILERSMNLTFTQLGI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IAFTLNMVSSVMQPVIGWYTDKRPMPYALPLGLTASMLGILGLAFAPSFLTILCCVFFIG
HHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSAVFHPEGSRVAYMAAGEKRGLAQSIYQVGGNTGQAMAPLITALILVPLGQFGSVWFT
CCCCEECCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LVAAIAVLFLIYIAKWYKGRLIHLRAVSKKSPASAVQTVITKPIILALIMIIFLIFARSW
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVSAIGNFYTFYAMNAYHVSIQQAQSYIFVFLFFGAVGTFLGGPLADRFGKRNVIIVSMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEE
ASAPLTIFLPFAGPVIAYGVLALIGVVLMSSFSVTVVYAQELVPGKIGTMSGLTVGLAFG
HHCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHH
MGAIGAVALGALIDSAGLTPTMTAVAFLPVLGLLAFVLPSDKTLKEWHS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure 
AIAAPLKEKPVHRPETTMYSILFIIGICHLLNDSLQAVIPAMFPILERSMNLTFTQLGI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IAFTLNMVSSVMQPVIGWYTDKRPMPYALPLGLTASMLGILGLAFAPSFLTILCCVFFIG
HHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSAVFHPEGSRVAYMAAGEKRGLAQSIYQVGGNTGQAMAPLITALILVPLGQFGSVWFT
CCCCEECCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LVAAIAVLFLIYIAKWYKGRLIHLRAVSKKSPASAVQTVITKPIILALIMIIFLIFARSW
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVSAIGNFYTFYAMNAYHVSIQQAQSYIFVFLFFGAVGTFLGGPLADRFGKRNVIIVSMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEE
ASAPLTIFLPFAGPVIAYGVLALIGVVLMSSFSVTVVYAQELVPGKIGTMSGLTVGLAFG
HHCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHH
MGAIGAVALGALIDSAGLTPTMTAVAFLPVLGLLAFVLPSDKTLKEWHS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: fosmidomycin [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: fosmidomycin [Cytoplasm] + Proton [Periplasm] = fosmidomycin [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]