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The map label for this gene is yveA [H]

Identifier: 154685085

GI number: 154685085

Start: 598290

End: 599852

Strand: Reverse

Name: yveA [H]

Synonym: RBAM_006230

Alternate gene names: 154685085

Gene position: 599852-598290 (Counterclockwise)

Preceding gene: 154685086

Following gene: 154685084

Centisome position: 15.31

GC content: 47.86

Gene sequence:

>1563_bases
ATGTCTAAGCAAGGAAACTTCCAGAAAACTATGTCACTTTTTGATCTTATTTTAATCGGCATGGGAGCCATATTCGGTTC
GGCATGGCTGTTTGCCGTCAGTAACGTCGCCTCTAAAGCGGGTCCATCAGGCGTTTTTTCCTGGCTGATCGGCGGGGGAA
TCATCTTATTGATCGGCTTGGTTTATGCGGAACTGGGCGCCGCGCTGCCGCGGACCGGGGGAATTATCCGGTATCCCGTA
TATTCACACGGACACCTCGTCGGATATTTAATTTCCTTTGTCACCATTGTGGCATACACGAGCCTTATTTCTATAGAAGT
CACGGCAGTCCGCCAATACGTGGCGTATTGGTTTCCCGGTTTGACCGTAAAAGGCTCTGATTCTCCGACAATTGCCGGGT
GGATATTGCAATTTGCGCTGCTCTGCCTGTTCTTCCTCCTCAATTACTGGAGTGTCAAAACCTTTGCGAAAGCAAACTTC
ATTATTTCGATTTTTAAATATGTCGTACCGATTACGGTAATTGTGGTACTGATTTTTCATTTTCACCCGGGCAATATGAC
CGTTCACGGATTCGCGCCTTTTGGTTTCACCGGAATTCAGGCCGCGATTTCCACAGGCGGCGTCATGTTTGCATACCTTG
GGCTGCATCCGATTGTGGCTGTCGCGAGTGAAGTGCAGAATCCGAAGCGGAACATTCCGATCGCATTGATTGTCTGTATT
ATCGTTTCTACTATTATTTACACCGTGCTGCAGCTCACTTTTATCGGGGCGATCCCGGCGGATACCCTGAAGCACGGATG
GCCGGCTATCGGGACTGAATTCTCCCTTCCGTTCAAAGATATCGCCGTTTTGCTCGGTTTGGGGTGGCTGGCGACATTGG
TCATTTTAGATGCGATTTTATCACCGGGCGGTAACGGAAATATCTTTATGAATACGACTTCACGTCTCGTCTATGCCTGG
GCCAGAAACGGAACATTATTCAGCATTTTTTCTAAAGTCAATAAAGAAACCGGGACACCGCGTGCCTCCCTTTGGCTTTC
GTTCGGTCTGGCTGTTTTTTGGACGCTTCCGTTCCCTTCTTGGAACGCTCTTGTCAACGTATGCTCCGTCGCATTGATTC
TGTCTTATGCGATTGCGCCGATTTCTTCTGCGGCGCTGAGAGTCAACGCGAAGAATATTAACAGACCGTTTTATTTAAAA
GGGATGAGCATCATCGGGCCGCTGTCGTTTATTTTTACCTCTTATATAGTATATTGGTCCGGATGGCGCACCGTATCCTG
GCTTCTCGGTTCTCAAATTGTCATGTTTCTGATCTATCTCTGTTTCAGTAAATATGCTCCCAAAGATGATGTCAGCATAC
GGCAGCAGCTGAAATCAGCATGGTGGATCGTCGGCTTTTATGTCATGATGCTGATTTTCTCCTATCTCGGCTCGTTCGGC
CACGGATTGGGCATTATCAGCAATCCGCTTGACCTGATTCTGATCGCCATCGGTTCGCTCGGTATTTATTACTGGGCAAA
ATATACGGGTCTGCCGAAGGCTATGATCGACAGTGATAAATGA

Upstream 100 bases:

>100_bases
TTCGAAAGTTGTCCTAATTTTCCAGCCGGCCGGCTGGGTATGTTTGAATGATAATGGGAATTATGTAAAGAGAACAATGT
CTTTTCTAAGGAGGCAGCGA

Downstream 100 bases:

>100_bases
TGAATGCCGGAAAGAAGTATGGTCTTCTTTCCGGTATTTTTATTTTAAGGATGACAAAAAAGAGAACATGCGATAAAATG
AATGACAGTCATTCATAAAA

Product: YveA

Products: NA

Alternate protein names: L-aspartate transporter [H]

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MSKQGNFQKTMSLFDLILIGMGAIFGSAWLFAVSNVASKAGPSGVFSWLIGGGIILLIGLVYAELGAALPRTGGIIRYPV
YSHGHLVGYLISFVTIVAYTSLISIEVTAVRQYVAYWFPGLTVKGSDSPTIAGWILQFALLCLFFLLNYWSVKTFAKANF
IISIFKYVVPITVIVVLIFHFHPGNMTVHGFAPFGFTGIQAAISTGGVMFAYLGLHPIVAVASEVQNPKRNIPIALIVCI
IVSTIIYTVLQLTFIGAIPADTLKHGWPAIGTEFSLPFKDIAVLLGLGWLATLVILDAILSPGGNGNIFMNTTSRLVYAW
ARNGTLFSIFSKVNKETGTPRASLWLSFGLAVFWTLPFPSWNALVNVCSVALILSYAIAPISSAALRVNAKNINRPFYLK
GMSIIGPLSFIFTSYIVYWSGWRTVSWLLGSQIVMFLIYLCFSKYAPKDDVSIRQQLKSAWWIVGFYVMMLIFSYLGSFG
HGLGIISNPLDLILIAIGSLGIYYWAKYTGLPKAMIDSDK

Sequences:

>Translated_520_residues
MSKQGNFQKTMSLFDLILIGMGAIFGSAWLFAVSNVASKAGPSGVFSWLIGGGIILLIGLVYAELGAALPRTGGIIRYPV
YSHGHLVGYLISFVTIVAYTSLISIEVTAVRQYVAYWFPGLTVKGSDSPTIAGWILQFALLCLFFLLNYWSVKTFAKANF
IISIFKYVVPITVIVVLIFHFHPGNMTVHGFAPFGFTGIQAAISTGGVMFAYLGLHPIVAVASEVQNPKRNIPIALIVCI
IVSTIIYTVLQLTFIGAIPADTLKHGWPAIGTEFSLPFKDIAVLLGLGWLATLVILDAILSPGGNGNIFMNTTSRLVYAW
ARNGTLFSIFSKVNKETGTPRASLWLSFGLAVFWTLPFPSWNALVNVCSVALILSYAIAPISSAALRVNAKNINRPFYLK
GMSIIGPLSFIFTSYIVYWSGWRTVSWLLGSQIVMFLIYLCFSKYAPKDDVSIRQQLKSAWWIVGFYVMMLIFSYLGSFG
HGLGIISNPLDLILIAIGSLGIYYWAKYTGLPKAMIDSDK
>Mature_519_residues
SKQGNFQKTMSLFDLILIGMGAIFGSAWLFAVSNVASKAGPSGVFSWLIGGGIILLIGLVYAELGAALPRTGGIIRYPVY
SHGHLVGYLISFVTIVAYTSLISIEVTAVRQYVAYWFPGLTVKGSDSPTIAGWILQFALLCLFFLLNYWSVKTFAKANFI
ISIFKYVVPITVIVVLIFHFHPGNMTVHGFAPFGFTGIQAAISTGGVMFAYLGLHPIVAVASEVQNPKRNIPIALIVCII
VSTIIYTVLQLTFIGAIPADTLKHGWPAIGTEFSLPFKDIAVLLGLGWLATLVILDAILSPGGNGNIFMNTTSRLVYAWA
RNGTLFSIFSKVNKETGTPRASLWLSFGLAVFWTLPFPSWNALVNVCSVALILSYAIAPISSAALRVNAKNINRPFYLKG
MSIIGPLSFIFTSYIVYWSGWRTVSWLLGSQIVMFLIYLCFSKYAPKDDVSIRQQLKSAWWIVGFYVMMLIFSYLGSFGH
GLGIISNPLDLILIAIGSLGIYYWAKYTGLPKAMIDSDK

Specific function: Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=453, Percent_Identity=23.6203090507726, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI114326544, Length=436, Percent_Identity=23.8532110091743, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI114326550, Length=436, Percent_Identity=23.8532110091743, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI258614005, Length=430, Percent_Identity=23.2558139534884, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI258614003, Length=430, Percent_Identity=23.2558139534884, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI110347453, Length=403, Percent_Identity=24.8138957816377, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI187423910, Length=402, Percent_Identity=24.8756218905473, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI7657591, Length=402, Percent_Identity=24.8756218905473, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI258645169, Length=433, Percent_Identity=22.8637413394919, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI9790235, Length=319, Percent_Identity=26.6457680250784, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI181337167, Length=403, Percent_Identity=22.0843672456576, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI115648063, Length=361, Percent_Identity=24.3767313019391, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI115648022, Length=361, Percent_Identity=24.3767313019391, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI186910308, Length=351, Percent_Identity=25.0712250712251, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI186910306, Length=351, Percent_Identity=25.0712250712251, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI186910304, Length=351, Percent_Identity=25.0712250712251, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081708, Length=363, Percent_Identity=26.4462809917355, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788480, Length=362, Percent_Identity=27.0718232044199, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1790653, Length=346, Percent_Identity=23.121387283237, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786302, Length=388, Percent_Identity=25, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI2367353, Length=451, Percent_Identity=25.4988913525499, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082250, Length=365, Percent_Identity=25.7534246575342, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789017, Length=392, Percent_Identity=22.9591836734694, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI48994972, Length=364, Percent_Identity=26.0989010989011, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786789, Length=419, Percent_Identity=22.9116945107399, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786602, Length=358, Percent_Identity=25.1396648044693, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081915, Length=413, Percent_Identity=22.7602905569007, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=405, Percent_Identity=24.4444444444444, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17568033, Length=347, Percent_Identity=26.5129682997118, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17532491, Length=427, Percent_Identity=25.0585480093677, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17531343, Length=413, Percent_Identity=23.2445520581114, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71995388, Length=305, Percent_Identity=25.5737704918033, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71995382, Length=305, Percent_Identity=25.5737704918033, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17533459, Length=422, Percent_Identity=23.2227488151659, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71993915, Length=368, Percent_Identity=23.9130434782609, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982608, Length=311, Percent_Identity=26.6881028938907, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71982612, Length=311, Percent_Identity=26.6881028938907, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32566699, Length=315, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24667468, Length=395, Percent_Identity=26.3291139240506, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI221331183, Length=353, Percent_Identity=26.3456090651558, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17647653, Length=353, Percent_Identity=26.3456090651558, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24664379, Length=353, Percent_Identity=26.3456090651558, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24668806, Length=460, Percent_Identity=24.1304347826087, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21356285, Length=460, Percent_Identity=24.1304347826087, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24668802, Length=460, Percent_Identity=24.1304347826087, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221512776, Length=412, Percent_Identity=23.5436893203883, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24666159, Length=412, Percent_Identity=23.5436893203883, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357367, Length=349, Percent_Identity=24.9283667621776, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24651635, Length=397, Percent_Identity=23.1738035264484, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651633, Length=397, Percent_Identity=23.1738035264484, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641995, Length=351, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641993, Length=404, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550968, Length=349, Percent_Identity=25.7879656160458, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19921172, Length=349, Percent_Identity=25.7879656160458, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 56890; Mature: 56759

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
>Mature Secondary Structure 
SKQGNFQKTMSLFDLILIGMGAIFGSAWLFAVSNVASKAGPSGVFSWLIGGGIILLIGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH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CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183 [H]