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The map label for this gene is ycnB [H]

Identifier: 154684878

GI number: 154684878

Start: 407240

End: 408664

Strand: Reverse

Name: ycnB [H]

Synonym: RBAM_004090

Alternate gene names: 154684878

Gene position: 408664-407240 (Counterclockwise)

Preceding gene: 154684879

Following gene: 154684873

Centisome position: 10.43

GC content: 52.84

Gene sequence:

>1425_bases
TTGAATAAGAGTATTGAAACTGCACCATACAACCGCTCTGTCATTGTCGGGATTCTTTTGGCGGGAGCGTTCGTCGCCAT
TTTGAACCAGACACTGCTTATCACGGCGCTGCCGCACATTATGAATGACTTCAATATAGACGCCAACAAAGCACAATGGC
TGACAACATCGTTTATGCTGACGAACGGGATTTTGATTCCGATTACCGCATTTTTAATAGAGAAATTCACGAGCCGCACC
CTCTTGATTTCCGCCATGAGTATTTTCACGGCGGGCACCATTGTCGGCGCATTCGCCCCGAATTTTCCGGTATTGTTAAC
GGCCCGGATTATCCAGGCAGCCGGCGCCGGAATTATGCTGCCTCTCATGCAGACGGTATTTCTCACGATTTTCCCGATGG
AAAAGCGCGGCCGCGCCATGGGTATGGTCGGCTTGGTTATTTCGTTCGCGCCGGCGATCGGCCCGACGCTTTCCGGATGG
GCGGTCGAAGCATTCTCTTGGCGGTCTTTGTTTTATATTATCTTCCCGATCGCAGTCATCGATTTGCTTTTAGCGATTAT
TCTGATGAAAAACGTCACGACATTACGAGAAACACAGATTGATATTTTATCCGTGATCTTATCGACCCTCGGATTCGGCG
GCCTGCTTTACGGCTTCTCAAGCGCCGGTTCATCAGGGTGGACCAGTGCTGAAGTGCTGACTTCGCTGCTTGTCGGAGCG
GTCGCGCTGATTTTCTTTATCGCAAGACAGATGAAGCTCAAAAAACCGATGCTGGAATTCCGCGTGTTTTCTTTCGGGAT
TTTCAGCCTGACCACCCTGCTCGGAACGCTTGTTTTCGCGCTGCTGATCGGAACGGAAACCATTCTCCCGCTTTACACGC
AAAAAGTCCGGGGCGTATCCGCGTTTGATACCGGATTAATGCTTTTGCCGGGCGCGATTGTGATGGGGATGATGTCTCCG
TTTATCGGCCGGGTGTTTGACAAAATCGGCGGAAAGGGCCTTGCGATGACCGGATTCTTCATCATCCTGCTCACGTCCCT
GCCGTTTATGAATCTGACGGACTCGACGTCTCTCATTTGGATTGTCGTCGTTTATACCGCGCGGCTTTTGGGAACAGCCA
TGATTATGATGCCGGTGACGACAGCGGGTATCAACGCCCTGCCGCGCCACTTAATTCCGCACGGCACAGCCATGAACAAT
ACCGTCCGCCAAGTCGGCGGTTCTATCGGTACGGCGCTGCTAGTTTCCGTGATGAGCAGCCAGGCCGCGCACGCAAATGC
GACAACTCCGGCAAACGCCGCCCTGCACGGCATGAATGCGGCATTTGTCGTAGCCGCCTGCATCGCGCTGGCCGGCTTCC
TCCTATCTTTTATATTGAAGAAAAAACCGCGTCAGCCCGAGCAGCAGCAGGCCGTTACGCGGTAA

Upstream 100 bases:

>100_bases
TAAAAGCGCTCATCGGTTATTTGGAGCAGGCCGGACCGCTGCACCAGCCGCTTGCAGCCGTTAAAACATTGCTCAAACTA
TAAAGAAAGAAGGAATCAGC

Downstream 100 bases:

>100_bases
ACCAAAAAGAACCCGATCACGTATGTGACCGGGTTCTTTTTTTACTTCTCGATTCCGTCTTTTACTTCTTTCACCATTTG
CGCCATGGATTCCAGGCCGC

Product: YcnB

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MNKSIETAPYNRSVIVGILLAGAFVAILNQTLLITALPHIMNDFNIDANKAQWLTTSFMLTNGILIPITAFLIEKFTSRT
LLISAMSIFTAGTIVGAFAPNFPVLLTARIIQAAGAGIMLPLMQTVFLTIFPMEKRGRAMGMVGLVISFAPAIGPTLSGW
AVEAFSWRSLFYIIFPIAVIDLLLAIILMKNVTTLRETQIDILSVILSTLGFGGLLYGFSSAGSSGWTSAEVLTSLLVGA
VALIFFIARQMKLKKPMLEFRVFSFGIFSLTTLLGTLVFALLIGTETILPLYTQKVRGVSAFDTGLMLLPGAIVMGMMSP
FIGRVFDKIGGKGLAMTGFFIILLTSLPFMNLTDSTSLIWIVVVYTARLLGTAMIMMPVTTAGINALPRHLIPHGTAMNN
TVRQVGGSIGTALLVSVMSSQAAHANATTPANAALHGMNAAFVVAACIALAGFLLSFILKKKPRQPEQQQAVTR

Sequences:

>Translated_474_residues
MNKSIETAPYNRSVIVGILLAGAFVAILNQTLLITALPHIMNDFNIDANKAQWLTTSFMLTNGILIPITAFLIEKFTSRT
LLISAMSIFTAGTIVGAFAPNFPVLLTARIIQAAGAGIMLPLMQTVFLTIFPMEKRGRAMGMVGLVISFAPAIGPTLSGW
AVEAFSWRSLFYIIFPIAVIDLLLAIILMKNVTTLRETQIDILSVILSTLGFGGLLYGFSSAGSSGWTSAEVLTSLLVGA
VALIFFIARQMKLKKPMLEFRVFSFGIFSLTTLLGTLVFALLIGTETILPLYTQKVRGVSAFDTGLMLLPGAIVMGMMSP
FIGRVFDKIGGKGLAMTGFFIILLTSLPFMNLTDSTSLIWIVVVYTARLLGTAMIMMPVTTAGINALPRHLIPHGTAMNN
TVRQVGGSIGTALLVSVMSSQAAHANATTPANAALHGMNAAFVVAACIALAGFLLSFILKKKPRQPEQQQAVTR
>Mature_474_residues
MNKSIETAPYNRSVIVGILLAGAFVAILNQTLLITALPHIMNDFNIDANKAQWLTTSFMLTNGILIPITAFLIEKFTSRT
LLISAMSIFTAGTIVGAFAPNFPVLLTARIIQAAGAGIMLPLMQTVFLTIFPMEKRGRAMGMVGLVISFAPAIGPTLSGW
AVEAFSWRSLFYIIFPIAVIDLLLAIILMKNVTTLRETQIDILSVILSTLGFGGLLYGFSSAGSSGWTSAEVLTSLLVGA
VALIFFIARQMKLKKPMLEFRVFSFGIFSLTTLLGTLVFALLIGTETILPLYTQKVRGVSAFDTGLMLLPGAIVMGMMSP
FIGRVFDKIGGKGLAMTGFFIILLTSLPFMNLTDSTSLIWIVVVYTARLLGTAMIMMPVTTAGINALPRHLIPHGTAMNN
TVRQVGGSIGTALLVSVMSSQAAHANATTPANAALHGMNAAFVVAACIALAGFLLSFILKKKPRQPEQQQAVTR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=431, Percent_Identity=26.2180974477958, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789042, Length=415, Percent_Identity=26.0240963855422, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI87081983, Length=407, Percent_Identity=27.7641277641278, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790195, Length=351, Percent_Identity=28.2051282051282, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788392, Length=464, Percent_Identity=25, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323735, Length=303, Percent_Identity=26.0726072607261, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6325455, Length=283, Percent_Identity=23.321554770318, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50718; Mature: 50718

Theoretical pI: Translated: 10.85; Mature: 10.85

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSIETAPYNRSVIVGILLAGAFVAILNQTLLITALPHIMNDFNIDANKAQWLTTSFML
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
TNGILIPITAFLIEKFTSRTLLISAMSIFTAGTIVGAFAPNFPVLLTARIIQAAGAGIML
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHH
PLMQTVFLTIFPMEKRGRAMGMVGLVISFAPAIGPTLSGWAVEAFSWRSLFYIIFPIAVI
HHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLLLAIILMKNVTTLRETQIDILSVILSTLGFGGLLYGFSSAGSSGWTSAEVLTSLLVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VALIFFIARQMKLKKPMLEFRVFSFGIFSLTTLLGTLVFALLIGTETILPLYTQKVRGVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
AFDTGLMLLPGAIVMGMMSPFIGRVFDKIGGKGLAMTGFFIILLTSLPFMNLTDSTSLIW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
IVVVYTARLLGTAMIMMPVTTAGINALPRHLIPHGTAMNNTVRQVGGSIGTALLVSVMSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QAAHANATTPANAALHGMNAAFVVAACIALAGFLLSFILKKKPRQPEQQQAVTR
HHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC
>Mature Secondary Structure
MNKSIETAPYNRSVIVGILLAGAFVAILNQTLLITALPHIMNDFNIDANKAQWLTTSFML
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
TNGILIPITAFLIEKFTSRTLLISAMSIFTAGTIVGAFAPNFPVLLTARIIQAAGAGIML
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHH
PLMQTVFLTIFPMEKRGRAMGMVGLVISFAPAIGPTLSGWAVEAFSWRSLFYIIFPIAVI
HHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLLLAIILMKNVTTLRETQIDILSVILSTLGFGGLLYGFSSAGSSGWTSAEVLTSLLVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VALIFFIARQMKLKKPMLEFRVFSFGIFSLTTLLGTLVFALLIGTETILPLYTQKVRGVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
AFDTGLMLLPGAIVMGMMSPFIGRVFDKIGGKGLAMTGFFIILLTSLPFMNLTDSTSLIW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHH
IVVVYTARLLGTAMIMMPVTTAGINALPRHLIPHGTAMNNTVRQVGGSIGTALLVSVMSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QAAHANATTPANAALHGMNAAFVVAACIALAGFLLSFILKKKPRQPEQQQAVTR
HHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]