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The map label for this gene is murQ

Identifier: 154684692

GI number: 154684692

Start: 195906

End: 196835

Strand: Reverse

Name: murQ

Synonym: RBAM_002180

Alternate gene names: 154684692

Gene position: 196835-195906 (Counterclockwise)

Preceding gene: 154684693

Following gene: 154684691

Centisome position: 5.02

GC content: 51.4

Gene sequence:

>930_bases
ATGACAGACCGGCTTAACATTCACAGATTGACCACAGAAACCAGAAATCCGCAGACCGCTTCAATCCATCAAGCAGACAC
GATGGAAATTCTCCGCATCATTAACCAAGAGGATTTCAAAGTGGCTGAAGCCGTTCAGCAGGTGCTGCCCGATATTCAGA
TTGCCGTTCAATTCGCCCATCAGTCCTTACGGCGAAACGGCAGGCTGATTTATGCGGGAGCGGGCACAAGCGGCAGACTC
GGTGTACTGGATGCGGTTGAATGCCCGCCTACATACAGCGTAAGTCCCGACACTGTCATCGGTCTGATGGCCGGAGGAGC
AGACGCCTTTTTGCAAGCGGCTGAAGGTATTGAAGACAGCGAGGAAACCGGCGCTCTCGATCTCAAAACGATCGGGCTTA
CCGCAGAAGACACCGTGATCGCCATCGCGGCAAGCGGGCGCACGCCGTATGCGGCCGGTGCGCTGAAATACGCAAAAACA
ATCGGCGCCAAAACTGTCGCGCTCACATGCAATAAACACTCATTGATCAGCACTTATGCCGATCACAGCATTGAAGTCGT
CGTCGGCCCCGAAGTGATTACAGGGTCAACACGAATGAAAGCGGCGACGGCACATAAAATGATTCTGAACATGATTTCCA
CGGCCGTGATGATCAAAAGCGGCAAAGTGTACGAAAATTTAATGGTGGACGTTCATGTGAGCAACGAAAAATTGAAAGAA
CGCGCAATCGGCATTATCCAAAGCATCACGGGCGTTCCGTACGACAAGGCAAAAGAAACGCTTGAGGCCGCAGGCAGCCA
TGTCAAAACGGCAATCGTCATGCTGAAGACGAATTCAGACGAAACACACGCGAAGGCACTGCTCAAAGAAGCGGAAGGCT
TCATTGACAAAGCCATTGAACAGCACGTTTCAAAAGAAAAAGAACGCTGA

Upstream 100 bases:

>100_bases
AAAGCGCTTGATTATTCATCTCATCCCTGCCGATTTTTCTTGAAACATCTATTCAGAAGCCCATATACTTCAAGTATTAA
CGACTTGGGAGGGTACAATC

Downstream 100 bases:

>100_bases
TCGTTCTTTGGTGAAAAATAATGTGCTTTTACGAGCCCGCGCCGTTTTCATGATCGGCGCAGGCGCTTTTAGGACGCGTT
TCAGGCACAGCTCCCCGGGA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTDRLNIHRLTTETRNPQTASIHQADTMEILRIINQEDFKVAEAVQQVLPDIQIAVQFAHQSLRRNGRLIYAGAGTSGRL
GVLDAVECPPTYSVSPDTVIGLMAGGADAFLQAAEGIEDSEETGALDLKTIGLTAEDTVIAIAASGRTPYAAGALKYAKT
IGAKTVALTCNKHSLISTYADHSIEVVVGPEVITGSTRMKAATAHKMILNMISTAVMIKSGKVYENLMVDVHVSNEKLKE
RAIGIIQSITGVPYDKAKETLEAAGSHVKTAIVMLKTNSDETHAKALLKEAEGFIDKAIEQHVSKEKER

Sequences:

>Translated_309_residues
MTDRLNIHRLTTETRNPQTASIHQADTMEILRIINQEDFKVAEAVQQVLPDIQIAVQFAHQSLRRNGRLIYAGAGTSGRL
GVLDAVECPPTYSVSPDTVIGLMAGGADAFLQAAEGIEDSEETGALDLKTIGLTAEDTVIAIAASGRTPYAAGALKYAKT
IGAKTVALTCNKHSLISTYADHSIEVVVGPEVITGSTRMKAATAHKMILNMISTAVMIKSGKVYENLMVDVHVSNEKLKE
RAIGIIQSITGVPYDKAKETLEAAGSHVKTAIVMLKTNSDETHAKALLKEAEGFIDKAIEQHVSKEKER
>Mature_308_residues
TDRLNIHRLTTETRNPQTASIHQADTMEILRIINQEDFKVAEAVQQVLPDIQIAVQFAHQSLRRNGRLIYAGAGTSGRLG
VLDAVECPPTYSVSPDTVIGLMAGGADAFLQAAEGIEDSEETGALDLKTIGLTAEDTVIAIAASGRTPYAAGALKYAKTI
GAKTVALTCNKHSLISTYADHSIEVVVGPEVITGSTRMKAATAHKMILNMISTAVMIKSGKVYENLMVDVHVSNEKLKER
AIGIIQSITGVPYDKAKETLEAAGSHVKTAIVMLKTNSDETHAKALLKEAEGFIDKAIEQHVSKEKER

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=298, Percent_Identity=50.6711409395973, Blast_Score=300, Evalue=6e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_BACA2 (A7Z0U6)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001419853.1
- ProteinModelPortal:   A7Z0U6
- SMR:   A7Z0U6
- STRING:   A7Z0U6
- EnsemblBacteria:   EBBACT00000005977
- GeneID:   5462442
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_002180
- eggNOG:   COG2103
- GeneTree:   EBGT00050000002902
- HOGENOM:   HBG703490
- OMA:   HLLTEQI
- ProtClustDB:   PRK05441
- BioCyc:   BAMY326423:RBAM_002180-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 33188; Mature: 33057

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 87-87 ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRLNIHRLTTETRNPQTASIHQADTMEILRIINQEDFKVAEAVQQVLPDIQIAVQFAH
CCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHH
QSLRRNGRLIYAGAGTSGRLGVLDAVECPPTYSVSPDTVIGLMAGGADAFLQAAEGIEDS
HHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCC
EETGALDLKTIGLTAEDTVIAIAASGRTPYAAGALKYAKTIGAKTVALTCNKHSLISTYA
CCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHC
DHSIEVVVGPEVITGSTRMKAATAHKMILNMISTAVMIKSGKVYENLMVDVHVSNEKLKE
CCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECHHHHHH
RAIGIIQSITGVPYDKAKETLEAAGSHVKTAIVMLKTNSDETHAKALLKEAEGFIDKAIE
HHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
QHVSKEKER
HHHHHHCCC
>Mature Secondary Structure 
TDRLNIHRLTTETRNPQTASIHQADTMEILRIINQEDFKVAEAVQQVLPDIQIAVQFAH
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHH
QSLRRNGRLIYAGAGTSGRLGVLDAVECPPTYSVSPDTVIGLMAGGADAFLQAAEGIEDS
HHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCC
EETGALDLKTIGLTAEDTVIAIAASGRTPYAAGALKYAKTIGAKTVALTCNKHSLISTYA
CCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHC
DHSIEVVVGPEVITGSTRMKAATAHKMILNMISTAVMIKSGKVYENLMVDVHVSNEKLKE
CCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECHHHHHH
RAIGIIQSITGVPYDKAKETLEAAGSHVKTAIVMLKTNSDETHAKALLKEAEGFIDKAIE
HHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
QHVSKEKER
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA