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The map label for this gene is nuoL [H]

Identifier: 154248541

GI number: 154248541

Start: 5108653

End: 5110578

Strand: Reverse

Name: nuoL [H]

Synonym: Xaut_4622

Alternate gene names: 154248541

Gene position: 5110578-5108653 (Counterclockwise)

Preceding gene: 154248542

Following gene: 154248540

Centisome position: 96.26

GC content: 63.19

Gene sequence:

>1926_bases
ATGTATCAGGCGATCGTCTTCTTCCCCCTTCTCGGCTTCCTCATCGCCGGTCTGTTCGGCCGTACCATGGGCGCGCGGGC
GAGCGAGGTGGTAACCACCTCCTTGCTCTTCATCGCCTGCTTCCTGGCCTGGATTGCGTTCTTCAGCGTCGGCTTCGGCG
ACCACGACACGCGCGTCCAGGTGATGCAGTGGATCCATGTGGGCGACCTCAAGGTCGACTGGGCGTTCCGGGTCGACACC
ATGACCGTGATCATGCTGATCGTGGTCACCACAGTGTCGTCTCTCGTGCACCTGTATTCCATCGGCTACATGCACGAGGA
CCCGAGCCGGCCGCGCTTCTTCGCCTATCTGTCGCTGTTCACCTTCGCCATGCTGATGCTGGTGACGGCGGACAACCTGC
TCCAGCTGTTCTTCGGCTGGGAGGGCGTGGGCCTTGCCTCCTACCTGCTCATCGGCTTCTGGTACGAGAAGCCCTCCGCC
AATGCGGCGGCCATGAAGGCCTTCGTGGTCAACCGTGTGGGTGACTTCGGCTTCATGCTGGGCATCTTCGCCATCTTCGT
GATGACCGGTTCCATCGCCTTCGAGCAGGTGTTCGCGGCGGCGCCGTCGTTGGCCGGCAAGACCATCCCCTTCCTCGGAC
ACCATTGGGATGCGCCCACGGTCATCGCCCTGCTGCTGTTCGTCGGCGCCATGGGCAAGTCGGCGCAGTTCCTGCTGCAC
ACCTGGCTGCCGGACGCCATGGAGGGCCCGACCCCGGTGTCCGCCCTCATCCACGCCGCCACCATGGTGACCGCCGGCGT
GTTCATGGTGGCGCGCATGTCGCCCATCTTCGAGCTGTCGCAGACCGCGCTCAACGTGGTGATGCTGATCGGTGCCACCA
CGGCCATGTTCGCGGCCACCGTGGCCCTGGTGCAGAACGACATCAAGAAGGTGATCGCCTATTCCACCTGTTCCCAGCTC
GGCTACATGTTCGTGGCCATGGGAGCCGGAGCCTATTCCATCGGCGTGTTCCACCTGGTGACGCACGCCTGCTTCAAGGC
GCTTCTGTTCCTCTGCGCCGGCTCGGTCATCAACGCGATGCACCATGAGCAGGACATGCGGCACATGGGCGGGCTCGCCA
AGAAGATCCCCTTCACCTACGTCATGATGCTGATCGGGACCCTGGCCATCACCGGCTTCCCCTTTCTTGCGGGCTACTAC
TCCAAGGACGCCATCATCGAGTCCGCGTGGGCCTCGCACAATTATTTCGCCCTCTACGGTTGGGTGATGACCGTGGCGGC
GGCGGCGCTGACCTCCTTCTATTCCTGGCGGCTGATCTTCCTCACCTTCCACGGCCACCCGCACGATCACCACCACTACG
AGGCGGCACATGAATCGCCGCGGGTGATGACCATTCCGCTCGGCGTGCTGGCGGTGGGATCGGTGATCGCGGGCTTCGCG
CTCTACAACGTGTTCGTGGGCGAGGGCGTGCACGACTTCTTCCGCCACTCCATCTTCATGGGTGCGGAAAACCACATCCT
TCACGAGATCCATGACATACCGCTGTGGGCGAAGTACCTACCGACGCTGATGATGGTGCTCGGCTTCTTGGTCGCCTACT
GGTTCTACGTGGTCGATCGCACGGTCCCGGTGGCGCTGGCCAAGTCGCAGGACGCGCTCTACCAGTTCCTGCTGAACAAG
TGGTACTTCGACGAGCTCTACGACCGCATCTTCGTAAAGCCGGCGCTGTGGATCGGCCGGCTGCTGTGGAAGCGCGGCGA
CGGCACCATCATTGACGGCTTCGGCCCCAACGGCGTGTCGGCGCGGGTGCTCGACGTCACGCGCGGGGTGGTGCGGCTCC
AGACCGGCTACCTCTACCACTACGCCTTCGTGATGCTCATCGGCGTCGCGGCTTTCATCACCTGGTTCATGTTCGCCGGA
GTGTGA

Upstream 100 bases:

>100_bases
GCGGCCGAGGCGGCCATCGGCCTCGCCATCCTCGTGGTGTTCTACCGCAACCGCGGTTCGATCGCCGTCGAGGACATCAA
CGCCATGAAGGGCTGAGGCC

Downstream 100 bases:

>100_bases
CGATGACCGACTGGCCCATCCTCTCCGTCGTAACCTTCCTGCCGCTGGTCGGCGCGCTCTTCATCCTGGTGGTGCGGGGC
GATGACGAGGTGACCGCACG

Product: proton-translocating NADH-quinone oxidoreductase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 641; Mature: 641

Protein sequence:

>641_residues
MYQAIVFFPLLGFLIAGLFGRTMGARASEVVTTSLLFIACFLAWIAFFSVGFGDHDTRVQVMQWIHVGDLKVDWAFRVDT
MTVIMLIVVTTVSSLVHLYSIGYMHEDPSRPRFFAYLSLFTFAMLMLVTADNLLQLFFGWEGVGLASYLLIGFWYEKPSA
NAAAMKAFVVNRVGDFGFMLGIFAIFVMTGSIAFEQVFAAAPSLAGKTIPFLGHHWDAPTVIALLLFVGAMGKSAQFLLH
TWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPIFELSQTALNVVMLIGATTAMFAATVALVQNDIKKVIAYSTCSQL
GYMFVAMGAGAYSIGVFHLVTHACFKALLFLCAGSVINAMHHEQDMRHMGGLAKKIPFTYVMMLIGTLAITGFPFLAGYY
SKDAIIESAWASHNYFALYGWVMTVAAAALTSFYSWRLIFLTFHGHPHDHHHYEAAHESPRVMTIPLGVLAVGSVIAGFA
LYNVFVGEGVHDFFRHSIFMGAENHILHEIHDIPLWAKYLPTLMMVLGFLVAYWFYVVDRTVPVALAKSQDALYQFLLNK
WYFDELYDRIFVKPALWIGRLLWKRGDGTIIDGFGPNGVSARVLDVTRGVVRLQTGYLYHYAFVMLIGVAAFITWFMFAG
V

Sequences:

>Translated_641_residues
MYQAIVFFPLLGFLIAGLFGRTMGARASEVVTTSLLFIACFLAWIAFFSVGFGDHDTRVQVMQWIHVGDLKVDWAFRVDT
MTVIMLIVVTTVSSLVHLYSIGYMHEDPSRPRFFAYLSLFTFAMLMLVTADNLLQLFFGWEGVGLASYLLIGFWYEKPSA
NAAAMKAFVVNRVGDFGFMLGIFAIFVMTGSIAFEQVFAAAPSLAGKTIPFLGHHWDAPTVIALLLFVGAMGKSAQFLLH
TWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPIFELSQTALNVVMLIGATTAMFAATVALVQNDIKKVIAYSTCSQL
GYMFVAMGAGAYSIGVFHLVTHACFKALLFLCAGSVINAMHHEQDMRHMGGLAKKIPFTYVMMLIGTLAITGFPFLAGYY
SKDAIIESAWASHNYFALYGWVMTVAAAALTSFYSWRLIFLTFHGHPHDHHHYEAAHESPRVMTIPLGVLAVGSVIAGFA
LYNVFVGEGVHDFFRHSIFMGAENHILHEIHDIPLWAKYLPTLMMVLGFLVAYWFYVVDRTVPVALAKSQDALYQFLLNK
WYFDELYDRIFVKPALWIGRLLWKRGDGTIIDGFGPNGVSARVLDVTRGVVRLQTGYLYHYAFVMLIGVAAFITWFMFAG
V
>Mature_641_residues
MYQAIVFFPLLGFLIAGLFGRTMGARASEVVTTSLLFIACFLAWIAFFSVGFGDHDTRVQVMQWIHVGDLKVDWAFRVDT
MTVIMLIVVTTVSSLVHLYSIGYMHEDPSRPRFFAYLSLFTFAMLMLVTADNLLQLFFGWEGVGLASYLLIGFWYEKPSA
NAAAMKAFVVNRVGDFGFMLGIFAIFVMTGSIAFEQVFAAAPSLAGKTIPFLGHHWDAPTVIALLLFVGAMGKSAQFLLH
TWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPIFELSQTALNVVMLIGATTAMFAATVALVQNDIKKVIAYSTCSQL
GYMFVAMGAGAYSIGVFHLVTHACFKALLFLCAGSVINAMHHEQDMRHMGGLAKKIPFTYVMMLIGTLAITGFPFLAGYY
SKDAIIESAWASHNYFALYGWVMTVAAAALTSFYSWRLIFLTFHGHPHDHHHYEAAHESPRVMTIPLGVLAVGSVIAGFA
LYNVFVGEGVHDFFRHSIFMGAENHILHEIHDIPLWAKYLPTLMMVLGFLVAYWFYVVDRTVPVALAKSQDALYQFLLNK
WYFDELYDRIFVKPALWIGRLLWKRGDGTIIDGFGPNGVSARVLDVTRGVVRLQTGYLYHYAFVMLIGVAAFITWFMFAG
V

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=432, Percent_Identity=41.8981481481481, Blast_Score=328, Evalue=7e-90,
Organism=Escherichia coli, GI1788614, Length=639, Percent_Identity=38.1846635367762, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1788829, Length=455, Percent_Identity=29.010989010989, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1788827, Length=435, Percent_Identity=28.9655172413793, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1788831, Length=355, Percent_Identity=28.169014084507, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI2367154, Length=215, Percent_Identity=30.6976744186047, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1788613, Length=280, Percent_Identity=27.1428571428571, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI145693160, Length=354, Percent_Identity=23.1638418079096, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 71177; Mature: 71177

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQAIVFFPLLGFLIAGLFGRTMGARASEVVTTSLLFIACFLAWIAFFSVGFGDHDTRVQ
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VMQWIHVGDLKVDWAFRVDTMTVIMLIVVTTVSSLVHLYSIGYMHEDPSRPRFFAYLSLF
HHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TFAMLMLVTADNLLQLFFGWEGVGLASYLLIGFWYEKPSANAAAMKAFVVNRVGDFGFML
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHH
GIFAIFVMTGSIAFEQVFAAAPSLAGKTIPFLGHHWDAPTVIALLLFVGAMGKSAQFLLH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
TWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPIFELSQTALNVVMLIGATTAMFAAT
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALVQNDIKKVIAYSTCSQLGYMFVAMGAGAYSIGVFHLVTHACFKALLFLCAGSVINAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HHEQDMRHMGGLAKKIPFTYVMMLIGTLAITGFPFLAGYYSKDAIIESAWASHNYFALYG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHH
WVMTVAAAALTSFYSWRLIFLTFHGHPHDHHHYEAAHESPRVMTIPLGVLAVGSVIAGFA
HHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCHHHCCCCCEEEECHHHHHHHHHHHHHH
LYNVFVGEGVHDFFRHSIFMGAENHILHEIHDIPLWAKYLPTLMMVLGFLVAYWFYVVDR
HHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
TVPVALAKSQDALYQFLLNKWYFDELYDRIFVKPALWIGRLLWKRGDGTIIDGFGPNGVS
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
ARVLDVTRGVVRLQTGYLYHYAFVMLIGVAAFITWFMFAGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYQAIVFFPLLGFLIAGLFGRTMGARASEVVTTSLLFIACFLAWIAFFSVGFGDHDTRVQ
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VMQWIHVGDLKVDWAFRVDTMTVIMLIVVTTVSSLVHLYSIGYMHEDPSRPRFFAYLSLF
HHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TFAMLMLVTADNLLQLFFGWEGVGLASYLLIGFWYEKPSANAAAMKAFVVNRVGDFGFML
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHH
GIFAIFVMTGSIAFEQVFAAAPSLAGKTIPFLGHHWDAPTVIALLLFVGAMGKSAQFLLH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
TWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPIFELSQTALNVVMLIGATTAMFAAT
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALVQNDIKKVIAYSTCSQLGYMFVAMGAGAYSIGVFHLVTHACFKALLFLCAGSVINAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HHEQDMRHMGGLAKKIPFTYVMMLIGTLAITGFPFLAGYYSKDAIIESAWASHNYFALYG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHH
WVMTVAAAALTSFYSWRLIFLTFHGHPHDHHHYEAAHESPRVMTIPLGVLAVGSVIAGFA
HHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCHHHCCCCCEEEECHHHHHHHHHHHHHH
LYNVFVGEGVHDFFRHSIFMGAENHILHEIHDIPLWAKYLPTLMMVLGFLVAYWFYVVDR
HHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
TVPVALAKSQDALYQFLLNKWYFDELYDRIFVKPALWIGRLLWKRGDGTIIDGFGPNGVS
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
ARVLDVTRGVVRLQTGYLYHYAFVMLIGVAAFITWFMFAGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]