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The map label for this gene is aapQ [H]

Identifier: 154248467

GI number: 154248467

Start: 5024907

End: 5026202

Strand: Direct

Name: aapQ [H]

Synonym: Xaut_4547

Alternate gene names: 154248467

Gene position: 5024907-5026202 (Clockwise)

Preceding gene: 154248466

Following gene: 154248468

Centisome position: 94.65

GC content: 67.13

Gene sequence:

>1296_bases
ATGTCGGATGTTCGCCTTTCGGGGCCACCGGCGGCGTCGCGCCGTCGCTGGTCATGGACGGATCCCAAGCTGCGCTCCTC
GGTGATCCAGATCGTCCTGGCTCTCATCATGGTGTGGCTGGTCTGGTCCTTCTATGCCAATGCGCAGGCCAACCTCTCCC
GCCTCGGCATCGCCTCCGGCTTCGGCTTCCTCGACAATCGCGCCGGCTTCGCCATCAGCCAGACGCTCATCCCCTACAAT
GAATCCATGAGCTACGGCCGCGCCTTCGTGGTGGGCCTGCTCAACACCCTGCTGGTGGCCTTCCTCGGCGTGGTCCTCGC
CACCCTCATCGGCTTCGTGATGGGCGTCGCGCGCCTCTCGAAGAACGTGGTGATCAAGGCGCTGGCCTCCGCCTACGTGG
AAATCACCCGCAACCTGCCGCCCCTGTTCCAGATCATGTTCTGGTATCTGGCGGTGCTCTCTACCCTGCCCGGCCCGCGG
CAGAGCTGGGGCTTCGGCCTCCAGCCCCTGTTCGGCGCCATCGGCTCCGGGCTCTCGGCCATCGGGCTGGGTTTCCTCGG
TACGCCCATATCGAACTTCGCGGCGGGCCTGGCGGCGCCTTCCGTGTTCGTGAACAATCGCGGCCTCGTGCTGCCGCGTC
CCGTGTTCGAGGAGGGCTCCATGGCCATCCTCTACGCCCTGATCGCGGCGGTGGTGGCGAGCTTTGTGCTCGCCCGCTGG
GCCAAGAAGCGGCGCGAGGCCACGGGCAAGCCGTTCCCGGCGTTCTGGGCGGGGCTCGCCCTCCTCATCGCCCTGCCGCT
CGCGGCCTCCTTTGCGGCGGGCAACCCCGTCACCATCGAAACCCCGGAGCTGCGCGGCTTCAACTTCGCCGGCGGGCTGA
AGGTCATCCCCGAATTCGTCGCGCTGCTGCTGGCGCTCGCCATCTACACCGGCGGCTTCATCGCCGAGATCGTCCGCTCG
GGCATTCTCGCCGTCTCCAAGGGCCAGAGCGAGGCGGCGCATTCCCTCGGCCTGAGGAACGGGCCGACGCTGCGCCTCGT
CATCATCCCGCAGGCCATGCGGGTGATCGTGCCGCCGCTCACCAGCCAGTATCTCAACCTCACCAAGAACTCGTCCCTGG
GCGTGGCGGTGGGCTATCCGGACCTGTTCGCCGTCTTCGCCGGCACCACGCTGAACCAGACCGGCCAGGCCATCGAAATC
ATCGCGGTGACCATGGCGGTCTACCTCACCATCTCGATCCTCACGTCGGCGATCATGGGCTGGTACAACAAGCGCGTCGC
GCTGGTGGAGCGGTGA

Upstream 100 bases:

>100_bases
GCTCAGCCTGCACACTTAAGCTGACGGTGGCGGACGCCCGGGGCGGCGCCCGCCACCACCAAAGATAAAGGGCTCAAAAG
CCCACACTTTCGGGGGTACC

Downstream 100 bases:

>100_bases
GATGAGCGACACCACCGTGCCCCTCTCCGCCCCCCGGGTCTCCCCCGCGCAGGCCTATGTGTCGACAACCCTGCGCGAGC
AGGAGCCGGCCCCCGTCGCC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSDVRLSGPPAASRRRWSWTDPKLRSSVIQIVLALIMVWLVWSFYANAQANLSRLGIASGFGFLDNRAGFAISQTLIPYN
ESMSYGRAFVVGLLNTLLVAFLGVVLATLIGFVMGVARLSKNVVIKALASAYVEITRNLPPLFQIMFWYLAVLSTLPGPR
QSWGFGLQPLFGAIGSGLSAIGLGFLGTPISNFAAGLAAPSVFVNNRGLVLPRPVFEEGSMAILYALIAAVVASFVLARW
AKKRREATGKPFPAFWAGLALLIALPLAASFAAGNPVTIETPELRGFNFAGGLKVIPEFVALLLALAIYTGGFIAEIVRS
GILAVSKGQSEAAHSLGLRNGPTLRLVIIPQAMRVIVPPLTSQYLNLTKNSSLGVAVGYPDLFAVFAGTTLNQTGQAIEI
IAVTMAVYLTISILTSAIMGWYNKRVALVER

Sequences:

>Translated_431_residues
MSDVRLSGPPAASRRRWSWTDPKLRSSVIQIVLALIMVWLVWSFYANAQANLSRLGIASGFGFLDNRAGFAISQTLIPYN
ESMSYGRAFVVGLLNTLLVAFLGVVLATLIGFVMGVARLSKNVVIKALASAYVEITRNLPPLFQIMFWYLAVLSTLPGPR
QSWGFGLQPLFGAIGSGLSAIGLGFLGTPISNFAAGLAAPSVFVNNRGLVLPRPVFEEGSMAILYALIAAVVASFVLARW
AKKRREATGKPFPAFWAGLALLIALPLAASFAAGNPVTIETPELRGFNFAGGLKVIPEFVALLLALAIYTGGFIAEIVRS
GILAVSKGQSEAAHSLGLRNGPTLRLVIIPQAMRVIVPPLTSQYLNLTKNSSLGVAVGYPDLFAVFAGTTLNQTGQAIEI
IAVTMAVYLTISILTSAIMGWYNKRVALVER
>Mature_430_residues
SDVRLSGPPAASRRRWSWTDPKLRSSVIQIVLALIMVWLVWSFYANAQANLSRLGIASGFGFLDNRAGFAISQTLIPYNE
SMSYGRAFVVGLLNTLLVAFLGVVLATLIGFVMGVARLSKNVVIKALASAYVEITRNLPPLFQIMFWYLAVLSTLPGPRQ
SWGFGLQPLFGAIGSGLSAIGLGFLGTPISNFAAGLAAPSVFVNNRGLVLPRPVFEEGSMAILYALIAAVVASFVLARWA
KKRREATGKPFPAFWAGLALLIALPLAASFAAGNPVTIETPELRGFNFAGGLKVIPEFVALLLALAIYTGGFIAEIVRSG
ILAVSKGQSEAAHSLGLRNGPTLRLVIIPQAMRVIVPPLTSQYLNLTKNSSLGVAVGYPDLFAVFAGTTLNQTGQAIEII
AVTMAVYLTISILTSAIMGWYNKRVALVER

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=414, Percent_Identity=49.0338164251208, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1786874, Length=148, Percent_Identity=33.7837837837838, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786873, Length=130, Percent_Identity=31.5384615384615, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787030, Length=138, Percent_Identity=32.6086956521739, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788226, Length=129, Percent_Identity=29.4573643410853, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082239, Length=97, Percent_Identity=36.0824742268041, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 46016; Mature: 45885

Theoretical pI: Translated: 10.94; Mature: 10.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVRLSGPPAASRRRWSWTDPKLRSSVIQIVLALIMVWLVWSFYANAQANLSRLGIASG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
FGFLDNRAGFAISQTLIPYNESMSYGRAFVVGLLNTLLVAFLGVVLATLIGFVMGVARLS
CCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNVVIKALASAYVEITRNLPPLFQIMFWYLAVLSTLPGPRQSWGFGLQPLFGAIGSGLSA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHH
IGLGFLGTPISNFAAGLAAPSVFVNNRGLVLPRPVFEEGSMAILYALIAAVVASFVLARW
HHHHHHCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AKKRREATGKPFPAFWAGLALLIALPLAASFAAGNPVTIETPELRGFNFAGGLKVIPEFV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHH
ALLLALAIYTGGFIAEIVRSGILAVSKGQSEAAHSLGLRNGPTLRLVIIPQAMRVIVPPL
HHHHHHHHHCCHHHHHHHHCCCEEEECCCHHHHHHCCCCCCCEEEEEEECCHHHHHCCCH
TSQYLNLTKNSSLGVAVGYPDLFAVFAGTTLNQTGQAIEIIAVTMAVYLTISILTSAIMG
HHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WYNKRVALVER
HHCCCEEEECC
>Mature Secondary Structure 
SDVRLSGPPAASRRRWSWTDPKLRSSVIQIVLALIMVWLVWSFYANAQANLSRLGIASG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
FGFLDNRAGFAISQTLIPYNESMSYGRAFVVGLLNTLLVAFLGVVLATLIGFVMGVARLS
CCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNVVIKALASAYVEITRNLPPLFQIMFWYLAVLSTLPGPRQSWGFGLQPLFGAIGSGLSA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHH
IGLGFLGTPISNFAAGLAAPSVFVNNRGLVLPRPVFEEGSMAILYALIAAVVASFVLARW
HHHHHHCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AKKRREATGKPFPAFWAGLALLIALPLAASFAAGNPVTIETPELRGFNFAGGLKVIPEFV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHH
ALLLALAIYTGGFIAEIVRSGILAVSKGQSEAAHSLGLRNGPTLRLVIIPQAMRVIVPPL
HHHHHHHHHCCHHHHHHHHCCCEEEECCCHHHHHHCCCCCCCEEEEEEECCHHHHHCCCH
TSQYLNLTKNSSLGVAVGYPDLFAVFAGTTLNQTGQAIEIIAVTMAVYLTISILTSAIMG
HHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WYNKRVALVER
HHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]