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The map label for this gene is trpD

Identifier: 154248296

GI number: 154248296

Start: 4851579

End: 4852613

Strand: Reverse

Name: trpD

Synonym: Xaut_4376

Alternate gene names: 154248296

Gene position: 4852613-4851579 (Counterclockwise)

Preceding gene: 154248297

Following gene: 154248295

Centisome position: 91.4

GC content: 69.18

Gene sequence:

>1035_bases
ATGAACGAGTTCAAACCCCTCCTCGGCAAGGTGGCCACCGGCGCGAGCCTCACCCGCGACGAGGCCGCCTACGTGTTCGA
CAAGATGATGTCGGGCGAGGCCACCCCCTCTCAGATGGGCGCGCTGCTCATGGGCCTGCGTGTGCGCGGCGAGACGGTGG
AGGAGATCGCCGGCGCGGTCTCCGTCATGCGGTCCAAGATGCTCTCCGTCGAGGCCCCCAGTGAAGCGGTGGACGTGGTG
GGTACCGGCGGCGATGCCTCCGGCTCCTACAACATCTCCACCTGCGCCTCCTTCATCGTGGCGGGGGCCGGCGTGCCGGT
GGCCAAGCACGGCAACCGGGCGCTGTCCTCCAAGTCGGGGGCGGCGGACGTGCTGGCGGCGCTGGGCGTGCGCATCGACC
TTGACCCGGCCGGCATCTCCCGCTGCATCGCGGAGGCCGGCATCGGCTTCATGTTCGCGCCCTCCCACCATCCGGCCATG
AAGCATGTGGGACCGACGCGGGTGGAGATGGGCACGCGCACCATCTTCAACCTCTTGGGGCCGCTCTCCAATCCGGCCGG
CGTCACCCGGCAGATGGTGGGCGTGTTCGCCAAGTCCTGGATCGTGCCGCTGGCAGAGGTGCTGCGGACGCTCGGGTCGC
AAAAGGCCTTCGTGGTGCACGGGTCCGACGGGCTGGACGAGATTACCATCTCCGGCGGCACCGACATCGCCGTGCTGGAC
GAGGGCCGCATCCACACCTTCACCATCATGCCGGAGGACGTGGGCCTCAAGCGCCATCCGGCCGAGGACCTGAAGGGCGG
CGACGCCGTGCATAATGCCAAGGCGCTTCGGACCGTGCTGGACGGAGCCGAGGGCGCCTATCGCGACGTGTCCCTGTTCA
ATGCCGCCGCTGCCCTGGTGGTGGCCGGCCGGGCCAAGGACCTGAAAGAGGGGGTCGAGATGGCACGGGTCAGCCTTGAC
ACCGGCTCCGCCCGCGCGCGGCTGGAGCACCTCGTGGCCGTATCTGAGAAACTGGCGCCGGAGGCGGCCCAATGA

Upstream 100 bases:

>100_bases
CGGAGAATGGCCACGCGCTGATCCGCAATTTCCTCGAAATCGCGGCCGCCTTCAATGCGCAGAAGGCCAAGGGCTGAGCA
CGAGAGGCTGAGGACGAGAC

Downstream 100 bases:

>100_bases
CCGATATTTTGAAGAAGATTGAAGCCTACAAGCGCGACGAGATTGCCGTCGCCAAGCATGCCCGTCCGCTGGGAGAGATC
GAGGCGGCGGCCCGTGCTGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNEFKPLLGKVATGASLTRDEAAYVFDKMMSGEATPSQMGALLMGLRVRGETVEEIAGAVSVMRSKMLSVEAPSEAVDVV
GTGGDASGSYNISTCASFIVAGAGVPVAKHGNRALSSKSGAADVLAALGVRIDLDPAGISRCIAEAGIGFMFAPSHHPAM
KHVGPTRVEMGTRTIFNLLGPLSNPAGVTRQMVGVFAKSWIVPLAEVLRTLGSQKAFVVHGSDGLDEITISGGTDIAVLD
EGRIHTFTIMPEDVGLKRHPAEDLKGGDAVHNAKALRTVLDGAEGAYRDVSLFNAAAALVVAGRAKDLKEGVEMARVSLD
TGSARARLEHLVAVSEKLAPEAAQ

Sequences:

>Translated_344_residues
MNEFKPLLGKVATGASLTRDEAAYVFDKMMSGEATPSQMGALLMGLRVRGETVEEIAGAVSVMRSKMLSVEAPSEAVDVV
GTGGDASGSYNISTCASFIVAGAGVPVAKHGNRALSSKSGAADVLAALGVRIDLDPAGISRCIAEAGIGFMFAPSHHPAM
KHVGPTRVEMGTRTIFNLLGPLSNPAGVTRQMVGVFAKSWIVPLAEVLRTLGSQKAFVVHGSDGLDEITISGGTDIAVLD
EGRIHTFTIMPEDVGLKRHPAEDLKGGDAVHNAKALRTVLDGAEGAYRDVSLFNAAAALVVAGRAKDLKEGVEMARVSLD
TGSARARLEHLVAVSEKLAPEAAQ
>Mature_344_residues
MNEFKPLLGKVATGASLTRDEAAYVFDKMMSGEATPSQMGALLMGLRVRGETVEEIAGAVSVMRSKMLSVEAPSEAVDVV
GTGGDASGSYNISTCASFIVAGAGVPVAKHGNRALSSKSGAADVLAALGVRIDLDPAGISRCIAEAGIGFMFAPSHHPAM
KHVGPTRVEMGTRTIFNLLGPLSNPAGVTRQMVGVFAKSWIVPLAEVLRTLGSQKAFVVHGSDGLDEITISGGTDIAVLD
EGRIHTFTIMPEDVGLKRHPAEDLKGGDAVHNAKALRTVLDGAEGAYRDVSLFNAAAALVVAGRAKDLKEGVEMARVSLD
TGSARARLEHLVAVSEKLAPEAAQ

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=333, Percent_Identity=37.5375375375375, Blast_Score=216, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320561, Length=326, Percent_Identity=29.7546012269939, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_XANP2 (A7INK3)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001419254.1
- ProteinModelPortal:   A7INK3
- SMR:   A7INK3
- STRING:   A7INK3
- GeneID:   5422939
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_4376
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   ATPSQMG
- ProtClustDB:   PRK00188
- BioCyc:   XAUT78245:XAUT_4376-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35651; Mature: 35651

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFKPLLGKVATGASLTRDEAAYVFDKMMSGEATPSQMGALLMGLRVRGETVEEIAGAV
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
SVMRSKMLSVEAPSEAVDVVGTGGDASGSYNISTCASFIVAGAGVPVAKHGNRALSSKSG
HHHHHHHHCCCCCCHHEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCC
AADVLAALGVRIDLDPAGISRCIAEAGIGFMFAPSHHPAMKHVGPTRVEMGTRTIFNLLG
HHHHHHHHCCEEECCHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCHHHHHHHHHHHHHC
PLSNPAGVTRQMVGVFAKSWIVPLAEVLRTLGSQKAFVVHGSDGLDEITISGGTDIAVLD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEEE
EGRIHTFTIMPEDVGLKRHPAEDLKGGDAVHNAKALRTVLDGAEGAYRDVSLFNAAAALV
CCCEEEEEECCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VAGRAKDLKEGVEMARVSLDTGSARARLEHLVAVSEKLAPEAAQ
HHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNEFKPLLGKVATGASLTRDEAAYVFDKMMSGEATPSQMGALLMGLRVRGETVEEIAGAV
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
SVMRSKMLSVEAPSEAVDVVGTGGDASGSYNISTCASFIVAGAGVPVAKHGNRALSSKSG
HHHHHHHHCCCCCCHHEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHCCCCC
AADVLAALGVRIDLDPAGISRCIAEAGIGFMFAPSHHPAMKHVGPTRVEMGTRTIFNLLG
HHHHHHHHCCEEECCHHHHHHHHHHHCCCEEECCCCCCHHHCCCCCHHHHHHHHHHHHHC
PLSNPAGVTRQMVGVFAKSWIVPLAEVLRTLGSQKAFVVHGSDGLDEITISGGTDIAVLD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEEE
EGRIHTFTIMPEDVGLKRHPAEDLKGGDAVHNAKALRTVLDGAEGAYRDVSLFNAAAALV
CCCEEEEEECCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VAGRAKDLKEGVEMARVSLDTGSARARLEHLVAVSEKLAPEAAQ
HHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA