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The map label for this gene is iorA [H]

Identifier: 154248130

GI number: 154248130

Start: 4663001

End: 4663474

Strand: Reverse

Name: iorA [H]

Synonym: Xaut_4210

Alternate gene names: 154248130

Gene position: 4663474-4663001 (Counterclockwise)

Preceding gene: 154248143

Following gene: 154248129

Centisome position: 87.84

GC content: 69.62

Gene sequence:

>474_bases
ATGTCCGAGCCGGTTCAACTTCAGGTGAATGGCACAGCGCACCGCTTCGCGCTGCCCCGCTCCACGCCCCTCATCTATGT
GCTGCGCAACGACCTTGGCCTCAACGGCCCCAAGTTCGGCTGCGGGCTCGGGGAGTGCGGTGCCTGCACCGTGCTCATGG
ACGGGGTCGCCGCCCGCTCCTGCGTCACCACATTGGGCACGGCGGAAGGTCGCGCCATCACCACGCTGGAGGGGCTCGGC
ACCCCTGAGGCGCCCCACCCGGTGCAGGCCGCCTTCATCGCCGAGCAGGCGGCGCAATGTGGCTACTGCCTGAATGGCAT
GATCATGACCACCGTCGCCTTCCTCGCCCGCACCCCCGCCCCCACGGAGGACGAGGCCCGCGCCGCCCTGCGCTACAATC
TGTGTCGCTGCGGGACCCATGTGGAGATCCTGCGCGCGGTGATGCGCGCCGCCCACGGGGAGGCATCCGAATGA

Upstream 100 bases:

>100_bases
CGCGCTTGACGCCAGATCATTCGTATAGAAACAATCCAGGGAAGCGGGAGGCGTGCCGCTTCGCCTACACTGGCACGTCC
GATGACGGACCGAAACGAAG

Downstream 100 bases:

>100_bases
GCGAGCCGCGCCCCGACAAGGATCAGATCCTCGCTGCCACCGGCAATCTTTGCGTGCTGCGCCCGGCACAGTCGGTGGCC
GGCCTCCAGCGCAGCGCAAT

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSEPVQLQVNGTAHRFALPRSTPLIYVLRNDLGLNGPKFGCGLGECGACTVLMDGVAARSCVTTLGTAEGRAITTLEGLG
TPEAPHPVQAAFIAEQAAQCGYCLNGMIMTTVAFLARTPAPTEDEARAALRYNLCRCGTHVEILRAVMRAAHGEASE

Sequences:

>Translated_157_residues
MSEPVQLQVNGTAHRFALPRSTPLIYVLRNDLGLNGPKFGCGLGECGACTVLMDGVAARSCVTTLGTAEGRAITTLEGLG
TPEAPHPVQAAFIAEQAAQCGYCLNGMIMTTVAFLARTPAPTEDEARAALRYNLCRCGTHVEILRAVMRAAHGEASE
>Mature_156_residues
SEPVQLQVNGTAHRFALPRSTPLIYVLRNDLGLNGPKFGCGLGECGACTVLMDGVAARSCVTTLGTAEGRAITTLEGLGT
PEAPHPVQAAFIAEQAAQCGYCLNGMIMTTVAFLARTPAPTEDEARAALRYNLCRCGTHVEILRAVMRAAHGEASE

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=150, Percent_Identity=37.3333333333333, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI71773480, Length=90, Percent_Identity=37.7777777777778, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786480, Length=163, Percent_Identity=41.1042944785276, Blast_Score=123, Evalue=5e-30,
Organism=Escherichia coli, GI1789232, Length=146, Percent_Identity=41.7808219178082, Blast_Score=95, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17539860, Length=134, Percent_Identity=38.8059701492537, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=134, Percent_Identity=37.3134328358209, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17540638, Length=147, Percent_Identity=36.0544217687075, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17737937, Length=132, Percent_Identity=35.6060606060606, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647193, Length=161, Percent_Identity=32.9192546583851, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24647199, Length=136, Percent_Identity=33.0882352941176, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=31.4814814814815, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=31.4814814814815, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16502; Mature: 16371

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPVQLQVNGTAHRFALPRSTPLIYVLRNDLGLNGPKFGCGLGECGACTVLMDGVAARS
CCCCEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CVTTLGTAEGRAITTLEGLGTPEAPHPVQAAFIAEQAAQCGYCLNGMIMTTVAFLARTPA
HHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCC
PTEDEARAALRYNLCRCGTHVEILRAVMRAAHGEASE
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SEPVQLQVNGTAHRFALPRSTPLIYVLRNDLGLNGPKFGCGLGECGACTVLMDGVAARS
CCCEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CVTTLGTAEGRAITTLEGLGTPEAPHPVQAAFIAEQAAQCGYCLNGMIMTTVAFLARTPA
HHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCC
PTEDEARAALRYNLCRCGTHVEILRAVMRAAHGEASE
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]