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The map label for this gene is hxuC [H]

Identifier: 154248111

GI number: 154248111

Start: 4635826

End: 4638030

Strand: Reverse

Name: hxuC [H]

Synonym: Xaut_4191

Alternate gene names: 154248111

Gene position: 4638030-4635826 (Counterclockwise)

Preceding gene: 154248115

Following gene: 154248110

Centisome position: 87.36

GC content: 65.12

Gene sequence:

>2205_bases
ATGGCGCTCAGGCCGCAGACAGCGGGCGTTTGTATGTGGTCCAGCAGGCTTCTGCGTTCAGGCGTTGCCACCTGCGCGCT
GCTCGCCGGCATGGAGGGCGCGGCGTTCGCCCAGAGCGCGACACCCGCGACGGCTCAGGCCGAGACAGAGGGCGAGATGT
CCCTCGACACCATCACGGTGGCTGCCAGCCTCACGCCGGAGCGCACCATCGACGCCCTCGCCGCCATCAGCGTGGTGCGC
CCGGAAGACCTTGAGCAGCTCATGCCGTCGCGCACGCAGGACGTGTTCTTCGGCATGCCCGGCACCACGGTGATCCAGAA
CGGCAACTCGCCCCAGGCCTCCATCAACATCCGCGGCATGCAGGACTACGGGCGCGTGGCGGTGTTCGTGGACGGGGCGC
GGCAGAACTTCACGCAGCTCGGCCATGGCACCGGCGCCGGCTCCTTCTTCCTGGAGCCGGGCCTGCTCGCCGACGTGGAC
GTGGTGCGCGGCCCGGTCTCCAACATCTATGGCTCGGGCGCCATCGGCGGCGTGGTCACCATGCGCACCAAGGATGCCGA
CGACATCATCAAGAAGGGCCAGACCTGGGGCGTGGAATCCCTCGAAGAGTTCGGCTCCAACGGCCCCATGGGCTTTGGCT
CCCTGTTCGCCGCAGCGCGTGTGGGCCAGAACGTGGACCTGTTCCTCGGCGGCACCTATCGCACCCAGAGCGACTACAAG
GACGGCAACGGCGACGTGGTGCCCGGCACCGGCTACGACACCTGGACCGGCATCGCCAAGGCCACCTTCCGCCCGGCGGA
CTTTCACGAAGTGAAGTTCACCGGCCTCAACTACAATGCCGATTACACCACCTACAATGCGGCGCTGGTGAACGGTGCCA
TTCCTTCCACCGCCACCCAGTACGGCTCCACCGTGCTGAACCAGACCGCCACCGCGAGCTGGAACTACACCAATCCCAAT
GACAACGTGTTCGACTGGCGCAGCACCCTCTACTGGAACCGGGTGAAGCAGGACCAGATCAAGGTGGCCGGAACCGCAAG
CTCGGTGACGGGCGCCGTTGGCAATCCGCGCTATTTCACCATCGACACCGTGGGCTTCGACGCCAACAACACGTCGCGCT
TCGTCTGGAACGACATCCGCAACGCCATCACCATCGGCGGCGACTATTTCCACGACGACGTGAACAACGTGGACAATTAC
GGCTTCGGCGACGGCTACAACCCGTCGGGCGAGCGCGGCGTGGGCGGGGCCTTCGTGCAGTGGAAGGCCAATTATTCCAG
CTGGCTGGAAGCGCAGGCGGCGGTGCGCTACGACACCTACAGCCTCAACGGCGACGGCGTCTCCACTGATGGCCAGCGCT
TCTCGCCGAAGTTCACGCTGGGCATCACGCCCTGGAACTGGCTGACCTTCTACGGCACCTATGCGGAAGGCTACCGCGCC
CCGGCCGTGACCGAGACACTGGTGAACGGCGCGCACCCGCCGAACATCCCCCTCGTCTTCTGCCCGGACGGCAGCTATGG
CGTGTTCTGCTTCGTGCCCAATCCTTATCTCCAGCCGGAGGTGGGCAAGAACAAGGAGCTCGGCCTCAACGTCCGTTTCG
ACGATATCTTCGTGAACGGCGACAAGTTCCGTGCCAAGGCCAACATCTACCGCAACGACGTGGACGACTACATCGAGCTG
GTCGGCTATCAGATGACGCGCTACGGCACCTATGCCAACTACCAGTACCAGAACATCGCTCAGGCCCGCCTCCAGGGCTT
CGAGCTCGAAAGCAACTACGACGCGGGGGCGTGGTTCGCCGGCTTCAACGTGACCGTCTCAGACGGCGAGAACACAGAAA
CCGGCGGGCCGCTGTCCAACACCATGCCCAACAACGTGGCCGGCACGCTCGGCGCCCGCTTCCTCGACAAGAAGCTCACC
GTGTCTGTGCGCTGGCAGTGGGTGGCCGCCGTGACCGAGGCCGACATGCCGGCCGACGCGCCCTACGAGCCGACCCCGAG
CTTTAACCTCGTGAACGCCTATGTGGGCTACCAGCCCAGCGAGAACGTGCTCGCCTCGCTCTCCGTTGAGAACCTGCTCA
ACGAGCAGTACACTCAATACCAACAGTTCCTGCCCAGCGCCGGCCTCACCGTGAAGGGCGGGCTGCGCATCCGGTTCGGG
GCAGACACCATCGCCGCGGCGACCCCGTCTCCCCTCTACAAGTAG

Upstream 100 bases:

>100_bases
CGGTAGCTCAGGAGGGACAGGCGGGGATGCCCGCAGCGCGCCACGTCCGGAATGCGGACGGTAGCCAGCCCGATCACGCA
CCGATTCCGGAGAGACGATC

Downstream 100 bases:

>100_bases
CCACGCCGGTCCGGCGCAGCCATTCACCCCGTCACTTTTTGACACGTCGGAGTATGAGAAATGTTCATTGCCACCAACAG
GTTCAAGGTGAAGCACGGCT

Product: TonB-dependent heme/hemoglobin receptor family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 734; Mature: 733

Protein sequence:

>734_residues
MALRPQTAGVCMWSSRLLRSGVATCALLAGMEGAAFAQSATPATAQAETEGEMSLDTITVAASLTPERTIDALAAISVVR
PEDLEQLMPSRTQDVFFGMPGTTVIQNGNSPQASINIRGMQDYGRVAVFVDGARQNFTQLGHGTGAGSFFLEPGLLADVD
VVRGPVSNIYGSGAIGGVVTMRTKDADDIIKKGQTWGVESLEEFGSNGPMGFGSLFAAARVGQNVDLFLGGTYRTQSDYK
DGNGDVVPGTGYDTWTGIAKATFRPADFHEVKFTGLNYNADYTTYNAALVNGAIPSTATQYGSTVLNQTATASWNYTNPN
DNVFDWRSTLYWNRVKQDQIKVAGTASSVTGAVGNPRYFTIDTVGFDANNTSRFVWNDIRNAITIGGDYFHDDVNNVDNY
GFGDGYNPSGERGVGGAFVQWKANYSSWLEAQAAVRYDTYSLNGDGVSTDGQRFSPKFTLGITPWNWLTFYGTYAEGYRA
PAVTETLVNGAHPPNIPLVFCPDGSYGVFCFVPNPYLQPEVGKNKELGLNVRFDDIFVNGDKFRAKANIYRNDVDDYIEL
VGYQMTRYGTYANYQYQNIAQARLQGFELESNYDAGAWFAGFNVTVSDGENTETGGPLSNTMPNNVAGTLGARFLDKKLT
VSVRWQWVAAVTEADMPADAPYEPTPSFNLVNAYVGYQPSENVLASLSVENLLNEQYTQYQQFLPSAGLTVKGGLRIRFG
ADTIAAATPSPLYK

Sequences:

>Translated_734_residues
MALRPQTAGVCMWSSRLLRSGVATCALLAGMEGAAFAQSATPATAQAETEGEMSLDTITVAASLTPERTIDALAAISVVR
PEDLEQLMPSRTQDVFFGMPGTTVIQNGNSPQASINIRGMQDYGRVAVFVDGARQNFTQLGHGTGAGSFFLEPGLLADVD
VVRGPVSNIYGSGAIGGVVTMRTKDADDIIKKGQTWGVESLEEFGSNGPMGFGSLFAAARVGQNVDLFLGGTYRTQSDYK
DGNGDVVPGTGYDTWTGIAKATFRPADFHEVKFTGLNYNADYTTYNAALVNGAIPSTATQYGSTVLNQTATASWNYTNPN
DNVFDWRSTLYWNRVKQDQIKVAGTASSVTGAVGNPRYFTIDTVGFDANNTSRFVWNDIRNAITIGGDYFHDDVNNVDNY
GFGDGYNPSGERGVGGAFVQWKANYSSWLEAQAAVRYDTYSLNGDGVSTDGQRFSPKFTLGITPWNWLTFYGTYAEGYRA
PAVTETLVNGAHPPNIPLVFCPDGSYGVFCFVPNPYLQPEVGKNKELGLNVRFDDIFVNGDKFRAKANIYRNDVDDYIEL
VGYQMTRYGTYANYQYQNIAQARLQGFELESNYDAGAWFAGFNVTVSDGENTETGGPLSNTMPNNVAGTLGARFLDKKLT
VSVRWQWVAAVTEADMPADAPYEPTPSFNLVNAYVGYQPSENVLASLSVENLLNEQYTQYQQFLPSAGLTVKGGLRIRFG
ADTIAAATPSPLYK
>Mature_733_residues
ALRPQTAGVCMWSSRLLRSGVATCALLAGMEGAAFAQSATPATAQAETEGEMSLDTITVAASLTPERTIDALAAISVVRP
EDLEQLMPSRTQDVFFGMPGTTVIQNGNSPQASINIRGMQDYGRVAVFVDGARQNFTQLGHGTGAGSFFLEPGLLADVDV
VRGPVSNIYGSGAIGGVVTMRTKDADDIIKKGQTWGVESLEEFGSNGPMGFGSLFAAARVGQNVDLFLGGTYRTQSDYKD
GNGDVVPGTGYDTWTGIAKATFRPADFHEVKFTGLNYNADYTTYNAALVNGAIPSTATQYGSTVLNQTATASWNYTNPND
NVFDWRSTLYWNRVKQDQIKVAGTASSVTGAVGNPRYFTIDTVGFDANNTSRFVWNDIRNAITIGGDYFHDDVNNVDNYG
FGDGYNPSGERGVGGAFVQWKANYSSWLEAQAAVRYDTYSLNGDGVSTDGQRFSPKFTLGITPWNWLTFYGTYAEGYRAP
AVTETLVNGAHPPNIPLVFCPDGSYGVFCFVPNPYLQPEVGKNKELGLNVRFDDIFVNGDKFRAKANIYRNDVDDYIELV
GYQMTRYGTYANYQYQNIAQARLQGFELESNYDAGAWFAGFNVTVSDGENTETGGPLSNTMPNNVAGTLGARFLDKKLTV
SVRWQWVAAVTEADMPADAPYEPTPSFNLVNAYVGYQPSENVLASLSVENLLNEQYTQYQQFLPSAGLTVKGGLRIRFGA
DTIAAATPSPLYK

Specific function: Required for utilization of free heme at low concentrations [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=175, Percent_Identity=31.4285714285714, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788478, Length=142, Percent_Identity=33.8028169014084, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR011276
- InterPro:   IPR010949
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79532; Mature: 79401

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRPQTAGVCMWSSRLLRSGVATCALLAGMEGAAFAQSATPATAQAETEGEMSLDTITV
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCEEEEEEE
AASLTPERTIDALAAISVVRPEDLEQLMPSRTQDVFFGMPGTTVIQNGNSPQASINIRGM
EEECCCHHHHHHHHHHEECCCHHHHHHCCCCCCEEEEECCCCEEEECCCCCCEEEEEEEE
QDYGRVAVFVDGARQNFTQLGHGTGAGSFFLEPGLLADVDVVRGPVSNIYGSGAIGGVVT
CCCCCEEEEEECCHHHHHHHCCCCCCCCEEECCCCEECHHHHHCCHHHHCCCCCCCCEEE
MRTKDADDIIKKGQTWGVESLEEFGSNGPMGFGSLFAAARVGQNVDLFLGGTYRTQSDYK
EECCCHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCEEECCCCCC
DGNGDVVPGTGYDTWTGIAKATFRPADFHEVKFTGLNYNADYTTYNAALVNGAIPSTATQ
CCCCCEECCCCCCHHHCHHHHCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCHHHH
YGSTVLNQTATASWNYTNPNDNVFDWRSTLYWNRVKQDQIKVAGTASSVTGAVGNPRYFT
HHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEE
IDTVGFDANNTSRFVWNDIRNAITIGGDYFHDDVNNVDNYGFGDGYNPSGERGVGGAFVQ
EEEEEECCCCCCCCHHHHCCCEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
WKANYSSWLEAQAAVRYDTYSLNGDGVSTDGQRFSPKFTLGITPWNWLTFYGTYAEGYRA
EECCHHHHHHHHEEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEEEEHHCCCCC
PAVTETLVNGAHPPNIPLVFCPDGSYGVFCFVPNPYLQPEVGKNKELGLNVRFDDIFVNG
CHHHHHHHCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECC
DKFRAKANIYRNDVDDYIELVGYQMTRYGTYANYQYQNIAQARLQGFELESNYDAGAWFA
CCEEEEEHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEECCCCCCCEEEE
GFNVTVSDGENTETGGPLSNTMPNNVAGTLGARFLDKKLTVSVRWQWVAAVTEADMPADA
EEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEEEEEEEEECCCCCCCC
PYEPTPSFNLVNAYVGYQPSENVLASLSVENLLNEQYTQYQQFLPSAGLTVKGGLRIRFG
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEC
ADTIAAATPSPLYK
CCEEECCCCCCCCC
>Mature Secondary Structure 
ALRPQTAGVCMWSSRLLRSGVATCALLAGMEGAAFAQSATPATAQAETEGEMSLDTITV
CCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCEEEEEEE
AASLTPERTIDALAAISVVRPEDLEQLMPSRTQDVFFGMPGTTVIQNGNSPQASINIRGM
EEECCCHHHHHHHHHHEECCCHHHHHHCCCCCCEEEEECCCCEEEECCCCCCEEEEEEEE
QDYGRVAVFVDGARQNFTQLGHGTGAGSFFLEPGLLADVDVVRGPVSNIYGSGAIGGVVT
CCCCCEEEEEECCHHHHHHHCCCCCCCCEEECCCCEECHHHHHCCHHHHCCCCCCCCEEE
MRTKDADDIIKKGQTWGVESLEEFGSNGPMGFGSLFAAARVGQNVDLFLGGTYRTQSDYK
EECCCHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCEEECCCCCC
DGNGDVVPGTGYDTWTGIAKATFRPADFHEVKFTGLNYNADYTTYNAALVNGAIPSTATQ
CCCCCEECCCCCCHHHCHHHHCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCHHHH
YGSTVLNQTATASWNYTNPNDNVFDWRSTLYWNRVKQDQIKVAGTASSVTGAVGNPRYFT
HHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEE
IDTVGFDANNTSRFVWNDIRNAITIGGDYFHDDVNNVDNYGFGDGYNPSGERGVGGAFVQ
EEEEEECCCCCCCCHHHHCCCEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
WKANYSSWLEAQAAVRYDTYSLNGDGVSTDGQRFSPKFTLGITPWNWLTFYGTYAEGYRA
EECCHHHHHHHHEEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEEEEHHCCCCC
PAVTETLVNGAHPPNIPLVFCPDGSYGVFCFVPNPYLQPEVGKNKELGLNVRFDDIFVNG
CHHHHHHHCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECC
DKFRAKANIYRNDVDDYIELVGYQMTRYGTYANYQYQNIAQARLQGFELESNYDAGAWFA
CCEEEEEHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEECCCCCCCEEEE
GFNVTVSDGENTETGGPLSNTMPNNVAGTLGARFLDKKLTVSVRWQWVAAVTEADMPADA
EEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEEEEEEEEECCCCCCCC
PYEPTPSFNLVNAYVGYQPSENVLASLSVENLLNEQYTQYQQFLPSAGLTVKGGLRIRFG
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEC
ADTIAAATPSPLYK
CCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751272 [H]