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The map label for this gene is purQ [H]

Identifier: 154248012

GI number: 154248012

Start: 4530295

End: 4530993

Strand: Reverse

Name: purQ [H]

Synonym: Xaut_4091

Alternate gene names: 154248012

Gene position: 4530993-4530295 (Counterclockwise)

Preceding gene: 154248013

Following gene: 154248011

Centisome position: 85.35

GC content: 67.95

Gene sequence:

>699_bases
ATGAAACCAGCCGTCATCCTCTTCCCCGGCTCCAACCGTGAGCAGGACGCCGTGCGCGCGCTGCGCCTCGTCGCGGGCGC
GAAGCCGCAGGTGGTCTGGCACGCCGAGCATGAGCTGCCTCCCGGCACCGACCTCGTCGTGCTGCCCGGCGGCTTCTCCT
ATGGCGATTATCTGAGGTGCGGCGCCATCGCGGCCCGCGCCAACATCATGGAGGCCGTGCGCGCCCATGCGGCCCGCGGC
GGTCTGGTGCTCGGCATCTGCAACGGCTTCCAGATCCTGTGCGAGGCCGGCCTCTTGCCCGGCGTACTGGTGCGCAACGC
CCGCCTGCGCTTCGTCTGCCGCGAGGTGCTGCTGCGGGTGGAGCGGGCTGATACCGCCTTCACCAAGGCCTATCGCAAGA
GCGACCTCATCCGCATTCCCGTCGCCCATGGCGAGGGCAACTACACGGCGGACGAGACCACCATCGCCCGGCTGGAGCAC
GACGGGCGCATCGCCTTCCGCTACGCCCGCCGCGACGGCCAGATCGACCAGACCGATGGTCCCAACGGTGCCATCAACGG
CATCGCCGGCATCTATTCCGAGAAGTTCAACGTGCTTGGAATGATGCCGCATCCCGAAAATTACATCGAACCGGAAATCG
GCCCCACCGACGGCCGCGGCCTGTTCGAAAGCCTCGCCGGAGCCCTGAAGGCGGCGTGA

Upstream 100 bases:

>100_bases
ATGTGCTAGCATTTCGAATGCCGCATCGCCTGATCGAACGCCGGCTCGCCCTTGCCTGTGCCTTTGGCCGGTGCCACTGG
CCTGCGCCCATTGAGAGATC

Downstream 100 bases:

>100_bases
CCACGCCCCTCAATTCGGATCGAACCGCTGTGAATTCCATTCCCAACACGTCCCGCATCACCCCGGAGCTGGTGGCCGAG
CATGGCCTGAAGCCCGAGGA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKPAVILFPGSNREQDAVRALRLVAGAKPQVVWHAEHELPPGTDLVVLPGGFSYGDYLRCGAIAARANIMEAVRAHAARG
GLVLGICNGFQILCEAGLLPGVLVRNARLRFVCREVLLRVERADTAFTKAYRKSDLIRIPVAHGEGNYTADETTIARLEH
DGRIAFRYARRDGQIDQTDGPNGAINGIAGIYSEKFNVLGMMPHPENYIEPEIGPTDGRGLFESLAGALKAA

Sequences:

>Translated_232_residues
MKPAVILFPGSNREQDAVRALRLVAGAKPQVVWHAEHELPPGTDLVVLPGGFSYGDYLRCGAIAARANIMEAVRAHAARG
GLVLGICNGFQILCEAGLLPGVLVRNARLRFVCREVLLRVERADTAFTKAYRKSDLIRIPVAHGEGNYTADETTIARLEH
DGRIAFRYARRDGQIDQTDGPNGAINGIAGIYSEKFNVLGMMPHPENYIEPEIGPTDGRGLFESLAGALKAA
>Mature_232_residues
MKPAVILFPGSNREQDAVRALRLVAGAKPQVVWHAEHELPPGTDLVVLPGGFSYGDYLRCGAIAARANIMEAVRAHAARG
GLVLGICNGFQILCEAGLLPGVLVRNARLRFVCREVLLRVERADTAFTKAYRKSDLIRIPVAHGEGNYTADETTIARLEH
DGRIAFRYARRDGQIDQTDGPNGAINGIAGIYSEKFNVLGMMPHPENYIEPEIGPTDGRGLFESLAGALKAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=195, Percent_Identity=34.8717948717949, Blast_Score=82, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321498, Length=201, Percent_Identity=31.8407960199005, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24582111, Length=182, Percent_Identity=32.4175824175824, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24582109, Length=182, Percent_Identity=32.4175824175824, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17137292, Length=182, Percent_Identity=32.4175824175824, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25099; Mature: 25099

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAVILFPGSNREQDAVRALRLVAGAKPQVVWHAEHELPPGTDLVVLPGGFSYGDYLRC
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHH
GAIAARANIMEAVRAHAARGGLVLGICNGFQILCEAGLLPGVLVRNARLRFVCREVLLRV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHH
ERADTAFTKAYRKSDLIRIPVAHGEGNYTADETTIARLEHDGRIAFRYARRDGQIDQTDG
HHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCC
PNGAINGIAGIYSEKFNVLGMMPHPENYIEPEIGPTDGRGLFESLAGALKAA
CCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPAVILFPGSNREQDAVRALRLVAGAKPQVVWHAEHELPPGTDLVVLPGGFSYGDYLRC
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCCCCCHHHH
GAIAARANIMEAVRAHAARGGLVLGICNGFQILCEAGLLPGVLVRNARLRFVCREVLLRV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHH
ERADTAFTKAYRKSDLIRIPVAHGEGNYTADETTIARLEHDGRIAFRYARRDGQIDQTDG
HHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCC
PNGAINGIAGIYSEKFNVLGMMPHPENYIEPEIGPTDGRGLFESLAGALKAA
CCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]