Click here to switch to the map view.

The map label for this gene is lipB [H]

Identifier: 154248003

GI number: 154248003

Start: 4519402

End: 4520190

Strand: Reverse

Name: lipB [H]

Synonym: Xaut_4082

Alternate gene names: 154248003

Gene position: 4520190-4519402 (Counterclockwise)

Preceding gene: 154248004

Following gene: 154248000

Centisome position: 85.14

GC content: 70.34

Gene sequence:

>789_bases
ATGGCACGTTTGGGGGGACTGGACCCCACGGCGCGATGGATTAAACCATCTCCCATGATTGCCTCCGCCCCCCGCGCCAG
CCTAGAAACCCAGTTCCAGCCCACCGACCCCGAAGCCCCGCCGGTGGACTGGACCGTCAGCGATGGTCTCGTCCCCTACC
CCGAAGCGCTCGCCGCCATGGAGGCGCGCGTCGCCGCCATCGCCGAGGGCACGGCCCGCGAATGCGTCTGGCTGCTGGAA
CACCCGGCGCTCTACACCTCTGGCACCAGCGCCCGCCCCGAGGATCTCGTGGATGCGCGCTTTCCCGTCTACGAGACCGG
GCGCGGCGGTCAGTTCACCTATCACGGCCCCGGCCAGCGTGTGGCCTATGTGATGCTCGACCTGAAGCGCCGCTCGCCGG
ACGTACGCCGCTATGTGAGCGCGCTGGAGGCGTGGATCATCGGCACCCTGTCGGCGTTCAACGTGACCGGCGAGCGGCGG
GAGGATCGGGTCGGCGTCTGGGTGCGGCGGCGCGGCGGCGGCGAGGACAAGGTCGCCGCCATCGGCATCCGGGTGCGACG
CTGGGTGACCTTCCACGGCATCTCGCTGAACGTGGAGCCGGACCTGTCCCATTTCGGCGGCATCGTGCCCTGCGGCGTGC
GCGAGCACGGAGTGACGAGCCTCGCCGATCTCGGCCTGCCGGTGACCATGGGCGAGGTCGATTCGGTGCTGCGCGTGGCG
TTCGAGACCGTGTTCGGCCCGACCATTCCGGCAGCGGCGCCAACCGCCGGAGAGGCGGGCGAAGGCTGA

Upstream 100 bases:

>100_bases
CCGAAGCCCGTTGCGACGCGGGCGGGACTGCAAGATCAAGCAATGCCTCTCAGCGCCTCCGGCACTCTAGTATCCGTTCG
GCCAGCCTGGCCAAGGCCCA

Downstream 100 bases:

>100_bases
TAGCAATGGGCTTGACGTGTGGGCCAAGGGTCAGGCCCGTGCGGTGTTTGACCTCGATCCGCCCGCCACCTGTCGATGAC
AAACGCCGGCGGCATAAGGC

Product: lipoate-protein ligase B

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MARLGGLDPTARWIKPSPMIASAPRASLETQFQPTDPEAPPVDWTVSDGLVPYPEALAAMEARVAAIAEGTARECVWLLE
HPALYTSGTSARPEDLVDARFPVYETGRGGQFTYHGPGQRVAYVMLDLKRRSPDVRRYVSALEAWIIGTLSAFNVTGERR
EDRVGVWVRRRGGGEDKVAAIGIRVRRWVTFHGISLNVEPDLSHFGGIVPCGVREHGVTSLADLGLPVTMGEVDSVLRVA
FETVFGPTIPAAAPTAGEAGEG

Sequences:

>Translated_262_residues
MARLGGLDPTARWIKPSPMIASAPRASLETQFQPTDPEAPPVDWTVSDGLVPYPEALAAMEARVAAIAEGTARECVWLLE
HPALYTSGTSARPEDLVDARFPVYETGRGGQFTYHGPGQRVAYVMLDLKRRSPDVRRYVSALEAWIIGTLSAFNVTGERR
EDRVGVWVRRRGGGEDKVAAIGIRVRRWVTFHGISLNVEPDLSHFGGIVPCGVREHGVTSLADLGLPVTMGEVDSVLRVA
FETVFGPTIPAAAPTAGEAGEG
>Mature_261_residues
ARLGGLDPTARWIKPSPMIASAPRASLETQFQPTDPEAPPVDWTVSDGLVPYPEALAAMEARVAAIAEGTARECVWLLEH
PALYTSGTSARPEDLVDARFPVYETGRGGQFTYHGPGQRVAYVMLDLKRRSPDVRRYVSALEAWIIGTLSAFNVTGERRE
DRVGVWVRRRGGGEDKVAAIGIRVRRWVTFHGISLNVEPDLSHFGGIVPCGVREHGVTSLADLGLPVTMGEVDSVLRVAF
ETVFGPTIPAAAPTAGEAGEG

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Homo sapiens, GI221554520, Length=182, Percent_Identity=38.4615384615385, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI87081767, Length=165, Percent_Identity=42.4242424242424, Blast_Score=129, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323268, Length=143, Percent_Identity=37.7622377622378, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355483, Length=198, Percent_Identity=36.3636363636364, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 28241; Mature: 28110

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLGGLDPTARWIKPSPMIASAPRASLETQFQPTDPEAPPVDWTVSDGLVPYPEALAAM
CCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHH
EARVAAIAEGTARECVWLLEHPALYTSGTSARPEDLVDARFPVYETGRGGQFTYHGPGQR
HHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCHHHHHCCCCEEECCCCCEEEEECCCCE
VAYVMLDLKRRSPDVRRYVSALEAWIIGTLSAFNVTGERREDRVGVWVRRRGGGEDKVAA
EEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEE
IGIRVRRWVTFHGISLNVEPDLSHFGGIVPCGVREHGVTSLADLGLPVTMGEVDSVLRVA
EEEEEEEEEEEECEEEEECCCHHHHCCEEECCCCCCCCHHHHHCCCCEEHHHHHHHHHHH
FETVFGPTIPAAAPTAGEAGEG
HHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARLGGLDPTARWIKPSPMIASAPRASLETQFQPTDPEAPPVDWTVSDGLVPYPEALAAM
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHH
EARVAAIAEGTARECVWLLEHPALYTSGTSARPEDLVDARFPVYETGRGGQFTYHGPGQR
HHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCHHHHHCCCCEEECCCCCEEEEECCCCE
VAYVMLDLKRRSPDVRRYVSALEAWIIGTLSAFNVTGERREDRVGVWVRRRGGGEDKVAA
EEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEE
IGIRVRRWVTFHGISLNVEPDLSHFGGIVPCGVREHGVTSLADLGLPVTMGEVDSVLRVA
EEEEEEEEEEEECEEEEECCCHHHHCCEEECCCCCCCCHHHHHCCCCEEHHHHHHHHHHH
FETVFGPTIPAAAPTAGEAGEG
HHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA