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The map label for this gene is qor [H]

Identifier: 154247997

GI number: 154247997

Start: 4510261

End: 4511232

Strand: Reverse

Name: qor [H]

Synonym: Xaut_4076

Alternate gene names: 154247997

Gene position: 4511232-4510261 (Counterclockwise)

Preceding gene: 154247998

Following gene: 154247996

Centisome position: 84.97

GC content: 72.43

Gene sequence:

>972_bases
ATGCGCGGCTGGCGCGTCCATGAGATCACCGAAGACGGCGCCATGGTGTTCGGCGACTGCCCCGATCCGCGCCCGGCCCA
CGACGGCTGCGTGGTGAAGGTGGCGGCGGCGGGGGTCAACTTCCTCGACACGCTGATGATCCGCGGCCGCTACCAGGTGA
AGCCGCCTTTGCCCTTCACGCCCGGCATCGAGGTGGCCGGCACGGTGGTGGAGGCCGGGCCTAACAGCCCGTTCCGCCCC
GGCGACCGCCTGTGCGCGCTGATGGACCACGGCGGCTTCGCCGAGCATGCGGCGGTGCCGGCGCTGGGCGCGCAGAAGCT
GCCCGACGATTTCCCCCTGCGCGAGGCCGTGGCCCTGCCGGTGATCTATCCCACCGCCCACCTCGCCCTGCGCCACCGCG
CCGGCCTGAAGGCGGGGGAGACCGTGCTGGTGCATGCGGGCGCCGGCGGTGTCGGCTCCGCCGCGATCCAGCTGGCACGG
CACTGGGGGGCGCGGGTGATCGCCACTGCCGGCGGGCCGCAGAAGACCGCTTTGTGTCACGAGCTCGGCGCCGACGAGAC
CATTGATTATGCCGCCGAACCCCTGGTGGAGCGGGTGAAGGAGATCACCCACGGCCGGGGCGTGGATGTCATCGTCGATC
CGGTGGGCGGCAAGGTGGCGGTGGACAGCCTCAGGTGCCTCGCCTGGGGCGGGCGGCTCGTCATCGTCGGCTTTGCCGGC
GGGGCGGTGGCGGACCTGCCCTCCAACCGGCTGCTGCTGAAGAACGCCGCCGCCATGGGCGTCTATTGGGGCGCCTACCG
CCAGCATCATCCCGAGCTGGTAAGCGCCATGTTCGACGAATTGTTCGCCCTGCGCCGGAGCGGGGCCATCGCCCCGCTCA
TCCGCGATGTCTTCCCGCTGGCGCAGGCGCCGGCGGCGCTGGAGGCGCTGGCGGGCCGGCGCACCGTGGGCAAGGTGGTG
CTGGAGCCGTGA

Upstream 100 bases:

>100_bases
CGCGACGAGCTTAAAAAAGCCAAGGCCCGGCGCGGCAGCACCGCCGCCTATCTCGTCACCCCCAGCGCCCATCAGGCGTG
ATCGCAGAAAGGCATCCCCC

Downstream 100 bases:

>100_bases
GCGGGGCACGCCCCTCGCATAAAGTGATTTGAACGCCAGCGGACGGGTCCCGCGAAGCGGCCGCAAGTGCCGCGCCGGGC
CTGCCGGGAGGAAGCCATGA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MRGWRVHEITEDGAMVFGDCPDPRPAHDGCVVKVAAAGVNFLDTLMIRGRYQVKPPLPFTPGIEVAGTVVEAGPNSPFRP
GDRLCALMDHGGFAEHAAVPALGAQKLPDDFPLREAVALPVIYPTAHLALRHRAGLKAGETVLVHAGAGGVGSAAIQLAR
HWGARVIATAGGPQKTALCHELGADETIDYAAEPLVERVKEITHGRGVDVIVDPVGGKVAVDSLRCLAWGGRLVIVGFAG
GAVADLPSNRLLLKNAAAMGVYWGAYRQHHPELVSAMFDELFALRRSGAIAPLIRDVFPLAQAPAALEALAGRRTVGKVV
LEP

Sequences:

>Translated_323_residues
MRGWRVHEITEDGAMVFGDCPDPRPAHDGCVVKVAAAGVNFLDTLMIRGRYQVKPPLPFTPGIEVAGTVVEAGPNSPFRP
GDRLCALMDHGGFAEHAAVPALGAQKLPDDFPLREAVALPVIYPTAHLALRHRAGLKAGETVLVHAGAGGVGSAAIQLAR
HWGARVIATAGGPQKTALCHELGADETIDYAAEPLVERVKEITHGRGVDVIVDPVGGKVAVDSLRCLAWGGRLVIVGFAG
GAVADLPSNRLLLKNAAAMGVYWGAYRQHHPELVSAMFDELFALRRSGAIAPLIRDVFPLAQAPAALEALAGRRTVGKVV
LEP
>Mature_323_residues
MRGWRVHEITEDGAMVFGDCPDPRPAHDGCVVKVAAAGVNFLDTLMIRGRYQVKPPLPFTPGIEVAGTVVEAGPNSPFRP
GDRLCALMDHGGFAEHAAVPALGAQKLPDDFPLREAVALPVIYPTAHLALRHRAGLKAGETVLVHAGAGGVGSAAIQLAR
HWGARVIATAGGPQKTALCHELGADETIDYAAEPLVERVKEITHGRGVDVIVDPVGGKVAVDSLRCLAWGGRLVIVGFAG
GAVADLPSNRLLLKNAAAMGVYWGAYRQHHPELVSAMFDELFALRRSGAIAPLIRDVFPLAQAPAALEALAGRRTVGKVV
LEP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=31.5950920245399, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=31.5950920245399, Blast_Score=151, Evalue=6e-37,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=35.048231511254, Blast_Score=147, Evalue=9e-36,
Organism=Homo sapiens, GI22538446, Length=311, Percent_Identity=30.5466237942122, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI22538444, Length=311, Percent_Identity=30.5466237942122, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI194239676, Length=203, Percent_Identity=36.9458128078818, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI28557745, Length=274, Percent_Identity=34.3065693430657, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI24308257, Length=322, Percent_Identity=26.3975155279503, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI41872631, Length=321, Percent_Identity=29.595015576324, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI47519420, Length=326, Percent_Identity=27.6073619631902, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI67078404, Length=288, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI197927207, Length=196, Percent_Identity=28.0612244897959, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI67078406, Length=288, Percent_Identity=29.5138888888889, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI226059159, Length=153, Percent_Identity=32.0261437908497, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI226059133, Length=153, Percent_Identity=32.0261437908497, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI226056130, Length=153, Percent_Identity=32.0261437908497, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1790485, Length=306, Percent_Identity=35.2941176470588, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1790045, Length=337, Percent_Identity=24.9258160237389, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789651, Length=243, Percent_Identity=28.3950617283951, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=293, Percent_Identity=29.6928327645051, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17536829, Length=280, Percent_Identity=28.9285714285714, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI212642053, Length=310, Percent_Identity=27.4193548387097, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17556000, Length=300, Percent_Identity=26.3333333333333, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71987554, Length=381, Percent_Identity=25.7217847769029, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=30.5555555555556, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6323961, Length=284, Percent_Identity=27.8169014084507, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=340, Percent_Identity=26.1764705882353, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=279, Percent_Identity=27.2401433691756, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=288, Percent_Identity=26.7361111111111, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920632, Length=308, Percent_Identity=27.5974025974026, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI221330659, Length=308, Percent_Identity=27.5974025974026, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24581345, Length=300, Percent_Identity=28, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45550423, Length=289, Percent_Identity=27.681660899654, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33973; Mature: 33973

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGWRVHEITEDGAMVFGDCPDPRPAHDGCVVKVAAAGVNFLDTLMIRGRYQVKPPLPFT
CCCCEEEEECCCCCEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCEEECCCCCCC
PGIEVAGTVVEAGPNSPFRPGDRLCALMDHGGFAEHAAVPALGAQKLPDDFPLREAVALP
CCCCEEEEEEECCCCCCCCCHHHEEEEECCCCCHHHHCCCCCCHHCCCCCCCCHHHHCCC
VIYPTAHLALRHRAGLKAGETVLVHAGAGGVGSAAIQLARHWGARVIATAGGPQKTALCH
EEECHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHH
ELGADETIDYAAEPLVERVKEITHGRGVDVIVDPVGGKVAVDSLRCLAWGGRLVIVGFAG
HCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHEEEEEECCEEEEEEECC
GAVADLPSNRLLLKNAAAMGVYWGAYRQHHPELVSAMFDELFALRRSGAIAPLIRDVFPL
CEEECCCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AQAPAALEALAGRRTVGKVVLEP
HCCCHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure
MRGWRVHEITEDGAMVFGDCPDPRPAHDGCVVKVAAAGVNFLDTLMIRGRYQVKPPLPFT
CCCCEEEEECCCCCEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCEEECCCCCCC
PGIEVAGTVVEAGPNSPFRPGDRLCALMDHGGFAEHAAVPALGAQKLPDDFPLREAVALP
CCCCEEEEEEECCCCCCCCCHHHEEEEECCCCCHHHHCCCCCCHHCCCCCCCCHHHHCCC
VIYPTAHLALRHRAGLKAGETVLVHAGAGGVGSAAIQLARHWGARVIATAGGPQKTALCH
EEECHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHH
ELGADETIDYAAEPLVERVKEITHGRGVDVIVDPVGGKVAVDSLRCLAWGGRLVIVGFAG
HCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHEEEEEECCEEEEEEECC
GAVADLPSNRLLLKNAAAMGVYWGAYRQHHPELVSAMFDELFALRRSGAIAPLIRDVFPL
CEEECCCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AQAPAALEALAGRRTVGKVVLEP
HCCCHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]