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The map label for this gene is aatC [H]

Identifier: 154247450

GI number: 154247450

Start: 3926731

End: 3927951

Strand: Reverse

Name: aatC [H]

Synonym: Xaut_3522

Alternate gene names: 154247450

Gene position: 3927951-3926731 (Counterclockwise)

Preceding gene: 154247455

Following gene: 154247449

Centisome position: 73.99

GC content: 67.49

Gene sequence:

>1221_bases
ATGACGACCGACTTCCACCGCATTCGCCGGCTGCCGCCCTACGTGTTCGAGCAAGTGAACCGCGTGAAGGCCGCCGCCCG
TAATGCCGGGGCGGATATCGTCGACCTCGGCATGGGCAATCCGGATCTCGATGCGCCCGCGCATGTGATTGAGAAGCTCA
AGGAAACCATCGGCAAGCCGCGGACGGACCGCTATTCCGCGTCCAAGGGCATCCCCGGCCTGCGCCGCGCCCAGGCGGCC
TACTATGAGCGGCGATTCGGCGTGAAGCTGGATCCCGACAAGCACGTGGTGGCCACCCTCGGCTCGAAGGAAGGCTTCGC
CAACATGGCGCAGGCCATCACCGCGCCGGGCGACGTGATCCTGACCCCCAACCCGTCCTATCCCATCCACGCCTTCGGCT
TCCTGATGGCCGGCGGCGTGATCCGGTCGGTGCCGGTGGAGCCGGGGCCGGAGTTCTTCCACGCCATGGAACGGGCGGTG
CAGCACTCCATCCCCAAGCCCATCGCGGTGGTGCTGTGCTATCCGTCCAACCCCACGGCCTGCGTGGCGGACCTGGAGTT
CTACAAGGACGTGGTGGCCTTCGCGAAGAAGAACGACCTCATTGTCCTTTCCGACCTCGCCTATGCCGAGCTGTATTTCG
ACGACACCCCGCCGCCCTCGGTGCTGCAGGTGCCGGGCGCCATGGACGTGACGGTGGAATTCACCTCCATGTCCAAGACC
TATTCCATGGCCGGCTGGCGCATGGGCTTCGCGGTGGGCAACGAGCGCCTCATCGCCGCTTTGTCGCGGGTGAAGTCCTA
CCTTGATTACGGCGCCTACACCCCGATCCAGGTGGCGGCGACGGCGGCGCTCAACGGCCCGCAGGAATGCATCGCCGAGA
TGCGCGAGACCTACAAGAAGCGCCGAGACGCGCTGGTGGAGAGCTTCGGCCGCGCCGGCTTCCCGGTGCCCTCGCCCCGC
GCCTCCATGTTCGCCTGGGCGCCGATCCCCGAGCCGTTCCGTGCCATGGGCTCGGTAGAGTTCGCCAAGCTGCTCATCGA
GAAGGCGGACGTGGCGGTGGCGCCCGGCGTCGGCTTCGGCGAGCACGGGGACGACTTCGTCCGCATCGCCGTGGTGGAGA
ACGAGCAGCGCATCCGCCAGGCGGCGCGCAACATCCGCCGCTTCTTCGAGCAGGCGGGCACGACCCTCCACAATGTGGTG
CCCCTCAGCGCCGCGCGCTGA

Upstream 100 bases:

>100_bases
TCCCATCGCATTCATGGCTTTTCCATTCACACAACAGTGGTACAAAGCCCGACTGCCGCGCCGGGAGAATGAGCAACAGC
GCGGCCTCTGGAGCCCTGAG

Downstream 100 bases:

>100_bases
GGCCAAAGCCGGTGAGCAAGACTCACCGGTCTTAGGTCCAGCCCGCGCGGCGCTTGAGCGACCCCCTCTCGGCACCGGTC
GCAGACCGGGGCCGTCGGGA

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTTDFHRIRRLPPYVFEQVNRVKAAARNAGADIVDLGMGNPDLDAPAHVIEKLKETIGKPRTDRYSASKGIPGLRRAQAA
YYERRFGVKLDPDKHVVATLGSKEGFANMAQAITAPGDVILTPNPSYPIHAFGFLMAGGVIRSVPVEPGPEFFHAMERAV
QHSIPKPIAVVLCYPSNPTACVADLEFYKDVVAFAKKNDLIVLSDLAYAELYFDDTPPPSVLQVPGAMDVTVEFTSMSKT
YSMAGWRMGFAVGNERLIAALSRVKSYLDYGAYTPIQVAATAALNGPQECIAEMRETYKKRRDALVESFGRAGFPVPSPR
ASMFAWAPIPEPFRAMGSVEFAKLLIEKADVAVAPGVGFGEHGDDFVRIAVVENEQRIRQAARNIRRFFEQAGTTLHNVV
PLSAAR

Sequences:

>Translated_406_residues
MTTDFHRIRRLPPYVFEQVNRVKAAARNAGADIVDLGMGNPDLDAPAHVIEKLKETIGKPRTDRYSASKGIPGLRRAQAA
YYERRFGVKLDPDKHVVATLGSKEGFANMAQAITAPGDVILTPNPSYPIHAFGFLMAGGVIRSVPVEPGPEFFHAMERAV
QHSIPKPIAVVLCYPSNPTACVADLEFYKDVVAFAKKNDLIVLSDLAYAELYFDDTPPPSVLQVPGAMDVTVEFTSMSKT
YSMAGWRMGFAVGNERLIAALSRVKSYLDYGAYTPIQVAATAALNGPQECIAEMRETYKKRRDALVESFGRAGFPVPSPR
ASMFAWAPIPEPFRAMGSVEFAKLLIEKADVAVAPGVGFGEHGDDFVRIAVVENEQRIRQAARNIRRFFEQAGTTLHNVV
PLSAAR
>Mature_405_residues
TTDFHRIRRLPPYVFEQVNRVKAAARNAGADIVDLGMGNPDLDAPAHVIEKLKETIGKPRTDRYSASKGIPGLRRAQAAY
YERRFGVKLDPDKHVVATLGSKEGFANMAQAITAPGDVILTPNPSYPIHAFGFLMAGGVIRSVPVEPGPEFFHAMERAVQ
HSIPKPIAVVLCYPSNPTACVADLEFYKDVVAFAKKNDLIVLSDLAYAELYFDDTPPPSVLQVPGAMDVTVEFTSMSKTY
SMAGWRMGFAVGNERLIAALSRVKSYLDYGAYTPIQVAATAALNGPQECIAEMRETYKKRRDALVESFGRAGFPVPSPRA
SMFAWAPIPEPFRAMGSVEFAKLLIEKADVAVAPGVGFGEHGDDFVRIAVVENEQRIRQAARNIRRFFEQAGTTLHNVVP
LSAAR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=404, Percent_Identity=23.5148514851485, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI169881279, Length=404, Percent_Identity=23.5148514851485, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI56713256, Length=422, Percent_Identity=22.2748815165877, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI56713254, Length=422, Percent_Identity=22.2748815165877, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI169881281, Length=287, Percent_Identity=22.6480836236934, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI215599424, Length=384, Percent_Identity=21.3541666666667, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI19263340, Length=384, Percent_Identity=21.3541666666667, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788722, Length=389, Percent_Identity=52.6992287917738, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1786816, Length=359, Percent_Identity=25.3481894150418, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1788627, Length=384, Percent_Identity=25, Blast_Score=101, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=399, Percent_Identity=24.3107769423559, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=397, Percent_Identity=23.9294710327456, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=397, Percent_Identity=23.9294710327456, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=21.5384615384615, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=24.1645244215938, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=24.1645244215938, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=24.1645244215938, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=24.1645244215938, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44444; Mature: 44313

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDFHRIRRLPPYVFEQVNRVKAAARNAGADIVDLGMGNPDLDAPAHVIEKLKETIGKP
CCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
RTDRYSASKGIPGLRRAQAAYYERRFGVKLDPDKHVVATLGSKEGFANMAQAITAPGDVI
CCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCEEEECCCCCHHHHHHHHHCCCCCEE
LTPNPSYPIHAFGFLMAGGVIRSVPVEPGPEFFHAMERAVQHSIPKPIAVVLCYPSNPTA
ECCCCCCCHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCE
CVADLEFYKDVVAFAKKNDLIVLSDLAYAELYFDDTPPPSVLQVPGAMDVTVEFTSMSKT
EHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCEEECCCCEEEEEEEECCCHH
YSMAGWRMGFAVGNERLIAALSRVKSYLDYGAYTPIQVAATAALNGPQECIAEMRETYKK
HHHCCCEEHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
RRDALVESFGRAGFPVPSPRASMFAWAPIPEPFRAMGSVEFAKLLIEKADVAVAPGVGFG
HHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHCCHHHHHHHHHHCCEEECCCCCCC
EHGDDFVRIAVVENEQRIRQAARNIRRFFEQAGTTLHNVVPLSAAR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure 
TTDFHRIRRLPPYVFEQVNRVKAAARNAGADIVDLGMGNPDLDAPAHVIEKLKETIGKP
CCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
RTDRYSASKGIPGLRRAQAAYYERRFGVKLDPDKHVVATLGSKEGFANMAQAITAPGDVI
CCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCEEEECCCCCHHHHHHHHHCCCCCEE
LTPNPSYPIHAFGFLMAGGVIRSVPVEPGPEFFHAMERAVQHSIPKPIAVVLCYPSNPTA
ECCCCCCCHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCE
CVADLEFYKDVVAFAKKNDLIVLSDLAYAELYFDDTPPPSVLQVPGAMDVTVEFTSMSKT
EHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCEEECCCCEEEEEEEECCCHH
YSMAGWRMGFAVGNERLIAALSRVKSYLDYGAYTPIQVAATAALNGPQECIAEMRETYKK
HHHCCCEEHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
RRDALVESFGRAGFPVPSPRASMFAWAPIPEPFRAMGSVEFAKLLIEKADVAVAPGVGFG
HHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHCCHHHHHHHHHHCCEEECCCCCCC
EHGDDFVRIAVVENEQRIRQAARNIRRFFEQAGTTLHNVVPLSAAR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]