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The map label for this gene is acxB

Identifier: 154247438

GI number: 154247438

Start: 3908472

End: 3910802

Strand: Direct

Name: acxB

Synonym: Xaut_3510

Alternate gene names: 154247438

Gene position: 3908472-3910802 (Clockwise)

Preceding gene: 154247437

Following gene: 154247439

Centisome position: 73.62

GC content: 66.5

Gene sequence:

>2331_bases
ATGAACGTGACTGTTGACCAGAGCACCCTTGCGGGTGCGACGCGCGGCATCGTGCGCGGCGGCGAGACGCTGAAGGAGCA
TCGCGACCGCCTCATGGCCGCCACCAAGGCCACCGGCCGCTATGCCGGCCTGAAGACGCTGGAGCTGCGCGAGCGCGAGC
CCATCCTCTACAACAAGCTGTTCTCGCGCCTGCGGGCCGGCGTGGTGGATGCCCGCGAGACCGCCAAGAAGATCGCCGCC
TCCCCCATCGTGGAGCAGGAGGGCGAGCTGTGCTTCACCCTCTACAACGCGGCGGGCGACAGCCTTCTCACCTCCACCGG
CATCATCATCCATGTGGGAACCATGGGTGCCGCGATCAAATACATGATCGAGAACAATTGGGAGGCCAATCCCGGCGTCC
ACGACAAGGACATCTTCTGCAACAACGACAGCCTGATCGGAAACGTCCATCCGTGCGACATCCACACCATCGTGCCCATC
TTCTGGGAAGGTGAGCTGATCGGCTGGGTGGGCGGCGTCACCCACGTCATCGACACCGGCGCGGTGGGGCCGGGCTCCAT
GGCCACCGGGCAGGTGCAGCGCTTCGGCGACGGCTATTCCATCACCTGCCGCAAGGTGGGCGCCAACGACACCCTGTTCC
GCGACTGGCTGCACGAAAGCCAGCGCATGGTGCGCACCACCCGCTACTGGATGCTGGACGAGCGCACCCGCATCGCCGGC
TGCCACATGATCCGCAAGCTGGTGGAAGAGGTGGTCGCGGAAGAGGGCATCGAGGCCTACTGGAAGTTCGCCTACGAGGC
GGTGGAGCACGGCCGGCTCGGGCTCCAGGCCCGCATCAAGGCCATGACCATCCCCGGCACCTACCGGCAGGTGGGCTTCG
TGGATGTGCCCTACGCCCATGAGGACGTGCGGGTGCCCTCCGATTTCGCCAAGCTCGACACCATCATGCACGCCCCGTGC
GAGATGACGATCCGCCGGGACGGCACCTGGCGCCTCGACTTCGAGGGATCGAGCCGCTGGGGCTGGCACACCTACAACGC
CCACCAGGTGAGCTTCACCTCGGGCATCTGGGTGATGATGACCCAGACCCTCATCCCCTCCGAGATGATCAATGACGGCG
CCGCCTACGGCACCGAGTTCCGGCTGCCCAAGGGCACCTGGATGAACCCGGACGACCGCCGCGTCGCCTTCTCCTACAGC
TGGCACTTCCTGGTCTCGGCCTGGACGGCGCTGTGGCGGGGCCTGTCGCGCTCCTACTTCGGGCGCGGCTACCTGGAGGA
GGTCAACGCCGGCAACGCCAACACCTCCAACTGGCTGCAGGGCGGCGGCTTCAACCAGTATGACGAGATCCACGCCGTGA
ACTCGTTCGAGTGCGCCGCCAACGGCACCGGCGCCACCGCGGTGCAGGACGGCCTGTCCCACGCCGCCGCCATCTGGAAC
CCGGAAGGCGACATGGGTGACATGGAGATCTGGGAACTGGCCGAGCCGCTGGTCTATCTCGGCCGGCAGATCAAGGCGTC
GTCGGGCGGCTCCGGCAAGTATCGCGGCGGCTGCGGCTTCGAGAGCCTGCGCATGGTCTGGAACGCCAAGGACTGGACCA
TGTTCTTCATGGGCAACGGCCACATCTCCTCCGACTGGGGGCTGATGGGCGGTTATCCGGCGGCCTCCGGCTATCGCTTC
GCCGCCCACAAGACCAACCTGAAGGAACTGATCGCGTCCGGCGCGGAGATCCCGCTCGGCGGCGACACCGATCCGGAGAA
CCCGACCTGGGACGCCATGCTGCCCGACGCCCAGATCAAGCGCGACAAGCAGGCCATCACCACCGAGGAGATGTTCTCCG
ACTACGACCTCTACCTCAACTACATGCGCGGCGGCCCCGGCTTCGGTGATCCGCTCGACCGTGAGCCGCAGGCGGTGGCC
GACGACATCAATGGCGGCTACGTGCTGGAGCGCTTCGCCGGCGAGGTCTATGGCGTCGTGGTGCGGAAGGGCGCGGACGG
CCAGTATGGCGTGGACGAGGCCGGCACCGCCGCCGCCCGCGCGCAGATCCGCAAGGATCGCCTCGCCAAGTCAGTGCCGG
TCTCCGAATGGATGAAGGGCGAGCGCGAGAAGATCCTCGCCAAGGATGCGGGCACGCAGGTGCGGCAGATGTTTGCCGCC
TCCTTCAAGCTCGGCCCGCGCTTCGAGAAGGACTTCCGCACCTTCTGGAGCCTGCCCGACAGCTGGACCCTGCCGGAGGA
AGAAATCGGCGTGCCCACCTACGGCTCGCGCTATTCCATGGACATCTCCGAACTGCCCGACGTGCACACCGTGCAGTTCG
TGGAGGAATGA

Upstream 100 bases:

>100_bases
GCTCCCAGCCGCGAGGCGTGGATGGCCGGGACAAGCCCGGCCATGACGACGCGAAGAAGCACGCTCAATCCGAGTCAACG
AACTCAAAGGAAACGACCCC

Downstream 100 bases:

>100_bases
TCCCTCCACTGGGCGGCGGCGACAGCCGTCGCTGCCGCCCATTTTTTCCTTGGAAAACAAACATCAAGTGGAGGAAACAC
CATGGCCTATACCCGCTCGA

Product: hydantoinase B/oxoprolinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MNVTVDQSTLAGATRGIVRGGETLKEHRDRLMAATKATGRYAGLKTLELREREPILYNKLFSRLRAGVVDARETAKKIAA
SPIVEQEGELCFTLYNAAGDSLLTSTGIIIHVGTMGAAIKYMIENNWEANPGVHDKDIFCNNDSLIGNVHPCDIHTIVPI
FWEGELIGWVGGVTHVIDTGAVGPGSMATGQVQRFGDGYSITCRKVGANDTLFRDWLHESQRMVRTTRYWMLDERTRIAG
CHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRLGLQARIKAMTIPGTYRQVGFVDVPYAHEDVRVPSDFAKLDTIMHAPC
EMTIRRDGTWRLDFEGSSRWGWHTYNAHQVSFTSGIWVMMTQTLIPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYS
WHFLVSAWTALWRGLSRSYFGRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVQDGLSHAAAIWN
PEGDMGDMEIWELAEPLVYLGRQIKASSGGSGKYRGGCGFESLRMVWNAKDWTMFFMGNGHISSDWGLMGGYPAASGYRF
AAHKTNLKELIASGAEIPLGGDTDPENPTWDAMLPDAQIKRDKQAITTEEMFSDYDLYLNYMRGGPGFGDPLDREPQAVA
DDINGGYVLERFAGEVYGVVVRKGADGQYGVDEAGTAAARAQIRKDRLAKSVPVSEWMKGEREKILAKDAGTQVRQMFAA
SFKLGPRFEKDFRTFWSLPDSWTLPEEEIGVPTYGSRYSMDISELPDVHTVQFVEE

Sequences:

>Translated_776_residues
MNVTVDQSTLAGATRGIVRGGETLKEHRDRLMAATKATGRYAGLKTLELREREPILYNKLFSRLRAGVVDARETAKKIAA
SPIVEQEGELCFTLYNAAGDSLLTSTGIIIHVGTMGAAIKYMIENNWEANPGVHDKDIFCNNDSLIGNVHPCDIHTIVPI
FWEGELIGWVGGVTHVIDTGAVGPGSMATGQVQRFGDGYSITCRKVGANDTLFRDWLHESQRMVRTTRYWMLDERTRIAG
CHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRLGLQARIKAMTIPGTYRQVGFVDVPYAHEDVRVPSDFAKLDTIMHAPC
EMTIRRDGTWRLDFEGSSRWGWHTYNAHQVSFTSGIWVMMTQTLIPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYS
WHFLVSAWTALWRGLSRSYFGRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVQDGLSHAAAIWN
PEGDMGDMEIWELAEPLVYLGRQIKASSGGSGKYRGGCGFESLRMVWNAKDWTMFFMGNGHISSDWGLMGGYPAASGYRF
AAHKTNLKELIASGAEIPLGGDTDPENPTWDAMLPDAQIKRDKQAITTEEMFSDYDLYLNYMRGGPGFGDPLDREPQAVA
DDINGGYVLERFAGEVYGVVVRKGADGQYGVDEAGTAAARAQIRKDRLAKSVPVSEWMKGEREKILAKDAGTQVRQMFAA
SFKLGPRFEKDFRTFWSLPDSWTLPEEEIGVPTYGSRYSMDISELPDVHTVQFVEE
>Mature_776_residues
MNVTVDQSTLAGATRGIVRGGETLKEHRDRLMAATKATGRYAGLKTLELREREPILYNKLFSRLRAGVVDARETAKKIAA
SPIVEQEGELCFTLYNAAGDSLLTSTGIIIHVGTMGAAIKYMIENNWEANPGVHDKDIFCNNDSLIGNVHPCDIHTIVPI
FWEGELIGWVGGVTHVIDTGAVGPGSMATGQVQRFGDGYSITCRKVGANDTLFRDWLHESQRMVRTTRYWMLDERTRIAG
CHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRLGLQARIKAMTIPGTYRQVGFVDVPYAHEDVRVPSDFAKLDTIMHAPC
EMTIRRDGTWRLDFEGSSRWGWHTYNAHQVSFTSGIWVMMTQTLIPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYS
WHFLVSAWTALWRGLSRSYFGRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVQDGLSHAAAIWN
PEGDMGDMEIWELAEPLVYLGRQIKASSGGSGKYRGGCGFESLRMVWNAKDWTMFFMGNGHISSDWGLMGGYPAASGYRF
AAHKTNLKELIASGAEIPLGGDTDPENPTWDAMLPDAQIKRDKQAITTEEMFSDYDLYLNYMRGGPGFGDPLDREPQAVA
DDINGGYVLERFAGEVYGVVVRKGADGQYGVDEAGTAAARAQIRKDRLAKSVPVSEWMKGEREKILAKDAGTQVRQMFAA
SFKLGPRFEKDFRTFWSLPDSWTLPEEEIGVPTYGSRYSMDISELPDVHTVQFVEE

Specific function: Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACXB_XANP2 (Q8RM03)

Other databases:

- EMBL:   AF251789
- EMBL:   AY055852
- EMBL:   CP000781
- RefSeq:   YP_001418396.1
- STRING:   Q8RM03
- GeneID:   5424922
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_3510
- HOGENOM:   HBG334625
- OMA:   NPEGDMG
- ProtClustDB:   CLSK864234
- BioCyc:   MetaCyc:MONOMER-13282
- BioCyc:   XAUT78245:XAUT_3510-MONOMER
- InterPro:   IPR003692

Pfam domain/function: PF02538 Hydantoinase_B

EC number: =6.4.1.6

Molecular weight: Translated: 86343; Mature: 86343

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTVDQSTLAGATRGIVRGGETLKEHRDRLMAATKATGRYAGLKTLELREREPILYNKL
CCEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHH
FSRLRAGVVDARETAKKIAASPIVEQEGELCFTLYNAAGDSLLTSTGIIIHVGTMGAAIK
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEECCCEEEEECCCCCEEE
YMIENNWEANPGVHDKDIFCNNDSLIGNVHPCDIHTIVPIFWEGELIGWVGGVTHVIDTG
EEECCCCCCCCCCCCCCEEECCCCEECCCCCCCCEEEEEEEECCEEEEHHCCHHHHHHCC
AVGPGSMATGQVQRFGDGYSITCRKVGANDTLFRDWLHESQRMVRTTRYWMLDERTRIAG
CCCCCCCCCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
CHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRLGLQARIKAMTIPGTYRQVGFVDVPYAH
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHCCCEEECCCCC
EDVRVPSDFAKLDTIMHAPCEMTIRRDGTWRLDFEGSSRWGWHTYNAHQVSFTSGIWVMM
CCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCEEECCCEEEEECCCEEEEH
TQTLIPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYSWHFLVSAWTALWRGLSRSYF
HHHHCCHHHHCCCCCCCCEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHC
GRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVQDGLSHAAAIWN
CCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCCCCHHHHHHHHHHEEEEC
PEGDMGDMEIWELAEPLVYLGRQIKASSGGSGKYRGGCGFESLRMVWNAKDWTMFFMGNG
CCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHEECCCCEEEEEEECC
HISSDWGLMGGYPAASGYRFAAHKTNLKELIASGAEIPLGGDTDPENPTWDAMLPDAQIK
EECCCCCCCCCCCCCCCEEEEHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
RDKQAITTEEMFSDYDLYLNYMRGGPGFGDPLDREPQAVADDINGGYVLERFAGEVYGVV
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHCCEEEEE
VRKGADGQYGVDEAGTAAARAQIRKDRLAKSVPVSEWMKGEREKILAKDAGTQVRQMFAA
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHCCHHHHHHHHH
SFKLGPRFEKDFRTFWSLPDSWTLPEEEIGVPTYGSRYSMDISELPDVHTVQFVEE
HHCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEECCHHHCCCCEEEEEECC
>Mature Secondary Structure
MNVTVDQSTLAGATRGIVRGGETLKEHRDRLMAATKATGRYAGLKTLELREREPILYNKL
CCEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHH
FSRLRAGVVDARETAKKIAASPIVEQEGELCFTLYNAAGDSLLTSTGIIIHVGTMGAAIK
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEECCCEEEEECCCCCEEE
YMIENNWEANPGVHDKDIFCNNDSLIGNVHPCDIHTIVPIFWEGELIGWVGGVTHVIDTG
EEECCCCCCCCCCCCCCEEECCCCEECCCCCCCCEEEEEEEECCEEEEHHCCHHHHHHCC
AVGPGSMATGQVQRFGDGYSITCRKVGANDTLFRDWLHESQRMVRTTRYWMLDERTRIAG
CCCCCCCCCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
CHMIRKLVEEVVAEEGIEAYWKFAYEAVEHGRLGLQARIKAMTIPGTYRQVGFVDVPYAH
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHCCCEEECCCCC
EDVRVPSDFAKLDTIMHAPCEMTIRRDGTWRLDFEGSSRWGWHTYNAHQVSFTSGIWVMM
CCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCEEECCCEEEEECCCEEEEH
TQTLIPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYSWHFLVSAWTALWRGLSRSYF
HHHHCCHHHHCCCCCCCCEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHC
GRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTGATAVQDGLSHAAAIWN
CCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEECCCCCCCHHHHHHHHHHEEEEC
PEGDMGDMEIWELAEPLVYLGRQIKASSGGSGKYRGGCGFESLRMVWNAKDWTMFFMGNG
CCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHHHHHEECCCCEEEEEEECC
HISSDWGLMGGYPAASGYRFAAHKTNLKELIASGAEIPLGGDTDPENPTWDAMLPDAQIK
EECCCCCCCCCCCCCCCEEEEHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
RDKQAITTEEMFSDYDLYLNYMRGGPGFGDPLDREPQAVADDINGGYVLERFAGEVYGVV
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHCCEEEEE
VRKGADGQYGVDEAGTAAARAQIRKDRLAKSVPVSEWMKGEREKILAKDAGTQVRQMFAA
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHCCHHHHHHHHH
SFKLGPRFEKDFRTFWSLPDSWTLPEEEIGVPTYGSRYSMDISELPDVHTVQFVEE
HHCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEECCHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12003937