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The map label for this gene is chaA [C]

Identifier: 154247421

GI number: 154247421

Start: 3889842

End: 3891002

Strand: Direct

Name: chaA [C]

Synonym: Xaut_3493

Alternate gene names: 154247421

Gene position: 3889842-3891002 (Clockwise)

Preceding gene: 154247420

Following gene: 154247422

Centisome position: 73.27

GC content: 66.67

Gene sequence:

>1161_bases
TTGCGACGCCAGGGCGGATGTGGGACAGCGGAAGGCGAACCCAGCGGCGAGGAGCACAGCGTGAAGGCAAGCGGGCCGAC
GGCGCTCAATTACGTCCTGCCGGGAATGGGCCTCGCGCTCGCGCTGCTGCTGAAGGTCTGGCCGGATCTGGCGCCGGGCG
CCGAGGGCGTGGTGCCGGGCTTCGCCGCGATCCTGGCCATCGCGCTGTTGTGCGGTTCGGCAGTCTCGTCGGTCGCCCAT
GCGGACGTGGTGGCCCGCCGCCTCGGCCAGCCCTACGGCGTGCTGCTGCTTACCATGTCGGTCACCATCATCGAGGTCTC
GGTGATGGCCTCGATGATGCTCCACGGCGAGAACAACCCGACCCTGGCGCGGGAATCGGTGTTTTCCGTGCTGATGATCG
TCAATACCGGCATCGTCGGCCTGTGCCTGCTGCTGGGCAGCCTCAGGCACCGGGAACAGACCATCCAGCAGCAGGGCGTC
TCCGGCTACCTCTCGGTGATGATCGCGCTGGGGGTGATGCTGCTGGTCCTGCCGGCCGAGACCCACGAGGGCGAGACCGG
CACCTTCTCCCCGCGCCAGCTCATCTTCATGAGCTTCGTCGCGGTCTCGCTCTATGGCGCCTTCCTCTACATGCAGACGG
TGCGCTACCGCGAGCACTTCGAGAACCAGCCGGAGGGACACAGCGAGGCGCCGCCCACGCCGAGCGCATTTGCGCTGGGC
CTGGTCATGCTGCTCGTGAGCCTTGCCGCGGTGGTCGCCTTGTCGAAGCACGTGGCGGCGGCCTTCGAGGACTTCCTCGG
CAATTTCGCGCTGGCCGATCCCGACGCGGTGACCGGCGCCCTCATCGCGCTGCTGATCCTGCTGCCGGAAGGCATCGCCG
CGGTGCGGGCGGCCTCCCGCAACCATCTCCAGCATTCGTTGAACATCGCGCTGGGCTCGGCGCTGGCCACGGTGGCGCTC
ACCATTCCGGCCATGGCCTTCATCTCGGTGATGATCGGTCATTCCATGGTCCTCGGCCTCGACACCGAGGACCGCACCAT
GCTGCTGGTCACCTTCGTGCTGTCCATCCTGTCGTTCGGGACAGGGCGGACCAACGCGCTGAACGGCGTTGTGCATCTCA
TCGTCTTCTGCGTCTATGTGATGCTGCTGTTCATGCCGTAA

Upstream 100 bases:

>100_bases
GGGCGACGCTGGCCTCGGTCTACCTGTGTCTCCTCGCCGAGCGCAAGGCGACCGGACGGCCGGTCGCGCTCTGAGGGGCG
CGGCGGGGCCGGGGTGACCC

Downstream 100 bases:

>100_bases
GGCGGGGTGGCGACCGGTGGACAGGCGGCGGGCCAGATGGCATGTTCCGCCCGATTTTTGAACGAGGCGCGGGCCGTGAA
GAACTTCCTGCTTTATATCT

Product: sodium/calcium exchanger membrane region

Products: Na (I) [Periplasm]; Ca (II) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRRQGGCGTAEGEPSGEEHSVKASGPTALNYVLPGMGLALALLLKVWPDLAPGAEGVVPGFAAILAIALLCGSAVSSVAH
ADVVARRLGQPYGVLLLTMSVTIIEVSVMASMMLHGENNPTLARESVFSVLMIVNTGIVGLCLLLGSLRHREQTIQQQGV
SGYLSVMIALGVMLLVLPAETHEGETGTFSPRQLIFMSFVAVSLYGAFLYMQTVRYREHFENQPEGHSEAPPTPSAFALG
LVMLLVSLAAVVALSKHVAAAFEDFLGNFALADPDAVTGALIALLILLPEGIAAVRAASRNHLQHSLNIALGSALATVAL
TIPAMAFISVMIGHSMVLGLDTEDRTMLLVTFVLSILSFGTGRTNALNGVVHLIVFCVYVMLLFMP

Sequences:

>Translated_386_residues
MRRQGGCGTAEGEPSGEEHSVKASGPTALNYVLPGMGLALALLLKVWPDLAPGAEGVVPGFAAILAIALLCGSAVSSVAH
ADVVARRLGQPYGVLLLTMSVTIIEVSVMASMMLHGENNPTLARESVFSVLMIVNTGIVGLCLLLGSLRHREQTIQQQGV
SGYLSVMIALGVMLLVLPAETHEGETGTFSPRQLIFMSFVAVSLYGAFLYMQTVRYREHFENQPEGHSEAPPTPSAFALG
LVMLLVSLAAVVALSKHVAAAFEDFLGNFALADPDAVTGALIALLILLPEGIAAVRAASRNHLQHSLNIALGSALATVAL
TIPAMAFISVMIGHSMVLGLDTEDRTMLLVTFVLSILSFGTGRTNALNGVVHLIVFCVYVMLLFMP
>Mature_386_residues
MRRQGGCGTAEGEPSGEEHSVKASGPTALNYVLPGMGLALALLLKVWPDLAPGAEGVVPGFAAILAIALLCGSAVSSVAH
ADVVARRLGQPYGVLLLTMSVTIIEVSVMASMMLHGENNPTLARESVFSVLMIVNTGIVGLCLLLGSLRHREQTIQQQGV
SGYLSVMIALGVMLLVLPAETHEGETGTFSPRQLIFMSFVAVSLYGAFLYMQTVRYREHFENQPEGHSEAPPTPSAFALG
LVMLLVSLAAVVALSKHVAAAFEDFLGNFALADPDAVTGALIALLILLPEGIAAVRAASRNHLQHSLNIALGSALATVAL
TIPAMAFISVMIGHSMVLGLDTEDRTMLLVTFVLSILSFGTGRTNALNGVVHLIVFCVYVMLLFMP

Specific function: Possible cation transporter [H]

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1787468, Length=341, Percent_Identity=36.6568914956012, Blast_Score=207, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 40627; Mature: 40627

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRQGGCGTAEGEPSGEEHSVKASGPTALNYVLPGMGLALALLLKVWPDLAPGAEGVVPG
CCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHH
FAAILAIALLCGSAVSSVAHADVVARRLGQPYGVLLLTMSVTIIEVSVMASMMLHGENNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TLARESVFSVLMIVNTGIVGLCLLLGSLRHREQTIQQQGVSGYLSVMIALGVMLLVLPAE
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCC
THEGETGTFSPRQLIFMSFVAVSLYGAFLYMQTVRYREHFENQPEGHSEAPPTPSAFALG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LVMLLVSLAAVVALSKHVAAAFEDFLGNFALADPDAVTGALIALLILLPEGIAAVRAASR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
NHLQHSLNIALGSALATVALTIPAMAFISVMIGHSMVLGLDTEDRTMLLVTFVLSILSFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCHHHHHHHHHHHHHCC
TGRTNALNGVVHLIVFCVYVMLLFMP
CCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRQGGCGTAEGEPSGEEHSVKASGPTALNYVLPGMGLALALLLKVWPDLAPGAEGVVPG
CCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHH
FAAILAIALLCGSAVSSVAHADVVARRLGQPYGVLLLTMSVTIIEVSVMASMMLHGENNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TLARESVFSVLMIVNTGIVGLCLLLGSLRHREQTIQQQGVSGYLSVMIALGVMLLVLPAE
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCC
THEGETGTFSPRQLIFMSFVAVSLYGAFLYMQTVRYREHFENQPEGHSEAPPTPSAFALG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LVMLLVSLAAVVALSKHVAAAFEDFLGNFALADPDAVTGALIALLILLPEGIAAVRAASR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
NHLQHSLNIALGSALATVALTIPAMAFISVMIGHSMVLGLDTEDRTMLLVTFVLSILSFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCHHHHHHHHHHHHHCC
TGRTNALNGVVHLIVFCVYVMLLFMP
CCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm]; Ca (II) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + Proton [Periplasm] = Proton [Cytoplasm] + Na (I) [Periplasm] Ca (II) [Cytoplasm] + Proton [Periplasm] = Ca (II) [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]