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The map label for this gene is pleC [H]

Identifier: 154247250

GI number: 154247250

Start: 3695616

End: 3696452

Strand: Reverse

Name: pleC [H]

Synonym: Xaut_3322

Alternate gene names: 154247250

Gene position: 3696452-3695616 (Counterclockwise)

Preceding gene: 154247257

Following gene: 154247247

Centisome position: 69.63

GC content: 72.76

Gene sequence:

>837_bases
GTGGCCGGCGGCGCGGCGGCACTGATCGCCGCGAGCCTCCTCGTCCTGCGGTCCCAGCGGCTGGAAGCGGCCCTGCGCGC
GGCCGAGGCGAGGGCCGATGCGGCCGAGGCGGCAGCGCGTCAGGCAACGGAGGAAAACCTCGCCAAATCGAGGTTCCTCG
CCGAAATGAGTCATGAGCTGCGCACCCCGCTGAACACGGTGATGGGCTTTTCCGAGATGATGGCGGACGAGGTGCTGGGT
CCCCATCGGGTGCCGGCCTATGGCACCTACGCGCGCGACATCCACGCCTCCGGCCAGCATCTTCTCGCGCTCGCCGACGA
CCTGCTCGACCTTGCCCGCATCGAGAGCGGCCACCGTACCCTCATGGAAACTCCGGTGCGGCTCGATGCCCTGGCGGAGG
ACTGCGTCGCCATGATGCGACCGCTGGCCTCCGGCGCCCGCGTGACCCTGACCGCCGAGGTGGCGGGCACGCCGCGCCTG
TGGGGGGACGAGCGGGCGCTGCGCCAGATCGCCCTCAACCTCCTGGCCAATGCGGTGAAATTCACGCCGCACCACGGCTC
GGTGCATCTGCTGGCCGGCATCGGTGCGGACGGCGTGCCGTTCCTCGCCGTGGAGGATACCGGGCCGGGCATCGCCGAGC
GCGAGCTGCCGCTGGGGGCGGCCCATCCCCGGGAAAGCCGTGTCGACCTCGCCACCGGACGCGGCGCCGGGCTGGGACTT
GCCATCGTGCGCGGCCTCGCCGGCCTGCACGGCGGCGCATTGGCGCTGGAGCGGCGGCCTGGCGGCGGCACGCGGGCCGA
AGTGACGTTTCCTCCCGCGCGCGCCCTGCACTCCTGA

Upstream 100 bases:

>100_bases
CCGCCCTGCCCGCAGCCTCGCAGGCCCATGGCTGGTGGCCGGTCTCGGCAGCTTCGGTCTGGCGCTGGCCGGCGGGGCCC
TGGCTGGAAGCCCCGGAGCC

Downstream 100 bases:

>100_bases
GCTTTCAGCCTTCGGACACCCCGGCCTCGGCGAAGGTGGCCATGCCACGATGGCAGGCCACCGCCGCCTTCACCACGCCG
ATGGCCAGCGCCGCGCCTGA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MAGGAAALIAASLLVLRSQRLEAALRAAEARADAAEAAARQATEENLAKSRFLAEMSHELRTPLNTVMGFSEMMADEVLG
PHRVPAYGTYARDIHASGQHLLALADDLLDLARIESGHRTLMETPVRLDALAEDCVAMMRPLASGARVTLTAEVAGTPRL
WGDERALRQIALNLLANAVKFTPHHGSVHLLAGIGADGVPFLAVEDTGPGIAERELPLGAAHPRESRVDLATGRGAGLGL
AIVRGLAGLHGGALALERRPGGGTRAEVTFPPARALHS

Sequences:

>Translated_278_residues
MAGGAAALIAASLLVLRSQRLEAALRAAEARADAAEAAARQATEENLAKSRFLAEMSHELRTPLNTVMGFSEMMADEVLG
PHRVPAYGTYARDIHASGQHLLALADDLLDLARIESGHRTLMETPVRLDALAEDCVAMMRPLASGARVTLTAEVAGTPRL
WGDERALRQIALNLLANAVKFTPHHGSVHLLAGIGADGVPFLAVEDTGPGIAERELPLGAAHPRESRVDLATGRGAGLGL
AIVRGLAGLHGGALALERRPGGGTRAEVTFPPARALHS
>Mature_277_residues
AGGAAALIAASLLVLRSQRLEAALRAAEARADAAEAAARQATEENLAKSRFLAEMSHELRTPLNTVMGFSEMMADEVLGP
HRVPAYGTYARDIHASGQHLLALADDLLDLARIESGHRTLMETPVRLDALAEDCVAMMRPLASGARVTLTAEVAGTPRLW
GDERALRQIALNLLANAVKFTPHHGSVHLLAGIGADGVPFLAVEDTGPGIAERELPLGAAHPRESRVDLATGRGAGLGLA
IVRGLAGLHGGALALERRPGGGTRAEVTFPPARALHS

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=32.8, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789149, Length=253, Percent_Identity=32.0158102766798, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=34.1880341880342, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081816, Length=252, Percent_Identity=32.9365079365079, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=30.4526748971193, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=31.0756972111554, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=30.8823529411765, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=30.1255230125523, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=26.431718061674, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=208, Percent_Identity=23.0769230769231, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=23.5772357723577, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=225, Percent_Identity=32, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=27.027027027027, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790861, Length=225, Percent_Identity=29.7777777777778, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=26.2931034482759, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 29081; Mature: 28950

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGGAAALIAASLLVLRSQRLEAALRAAEARADAAEAAARQATEENLAKSRFLAEMSHEL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPLNTVMGFSEMMADEVLGPHRVPAYGTYARDIHASGQHLLALADDLLDLARIESGHRT
HCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHH
LMETPVRLDALAEDCVAMMRPLASGARVTLTAEVAGTPRLWGDERALRQIALNLLANAVK
HHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
FTPHHGSVHLLAGIGADGVPFLAVEDTGPGIAERELPLGAAHPRESRVDLATGRGAGLGL
CCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHH
AIVRGLAGLHGGALALERRPGGGTRAEVTFPPARALHS
HHHHHHHCCCCCEEEEEECCCCCCEEEEECCCHHHHCC
>Mature Secondary Structure 
AGGAAALIAASLLVLRSQRLEAALRAAEARADAAEAAARQATEENLAKSRFLAEMSHEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPLNTVMGFSEMMADEVLGPHRVPAYGTYARDIHASGQHLLALADDLLDLARIESGHRT
HCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHH
LMETPVRLDALAEDCVAMMRPLASGARVTLTAEVAGTPRLWGDERALRQIALNLLANAVK
HHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
FTPHHGSVHLLAGIGADGVPFLAVEDTGPGIAERELPLGAAHPRESRVDLATGRGAGLGL
CCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHH
AIVRGLAGLHGGALALERRPGGGTRAEVTFPPARALHS
HHHHHHHCCCCCEEEEEECCCCCCEEEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]