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The map label for this gene is divL [H]

Identifier: 154247224

GI number: 154247224

Start: 3660205

End: 3662718

Strand: Direct

Name: divL [H]

Synonym: Xaut_3296

Alternate gene names: 154247224

Gene position: 3660205-3662718 (Clockwise)

Preceding gene: 154247223

Following gene: 154247225

Centisome position: 68.94

GC content: 72.2

Gene sequence:

>2514_bases
ATGGCGGACCGCATCCGGACCGGCGTTCCGCGCCAAAGGCGCGGGCGTGAGCAGGGCAGCGCTCACCGGGCGGTGGGGCT
GCGCCGGTTCTCCTTGCCGTCATGCTCGGTCCGTCCTGTCTGCGCCGGTCTCGCTGCGGTCTTCCTTTCTTCCACGCTGT
TCGTAAGCCCGGCTGCCGCCGGTTGGGATGCGGCCGCGACCGCGGCCGGCGCCCTTTGGCCGGTGGCGGGGCTTGCGGCT
GCCGCCATCGCCGGCCTTGCCGCCATGCGCAGCCATCGCGTGGCGAAGGACCTGCGCGGCCGCATTGAAGCCGCCGAACG
CGCCGCCGCGGATGCCGCCGCCTCCGCCGCCCGCGCCCGCGCCGAGGCCCAGGCCTGCCGTGTCCTCCTGTCCGATGGCG
CTCCGGCCTTCCTGCTGTGGACGGGGCGGGAGGCGCCGGCCGACCTGTTCGGCCGCACCCCTGAGACGCTAAAGGCCGAG
CTGGGGCCCGCCTCATCCGCCTTCGAAACCGCGCTCGCCCGTCTGAAGGCGGAGGATGGCGCCTTCTCCCAGACACTGGA
CACGCCCAGGGGGCCGCTGCGGCTCGACGGCAGGAGCCGGGCGGGCGCCGGCATCCTGCTGCTGGCCCCGCTCAGCAGCG
AAACGTCCGGGCATGAGGCTGGCCCGATGGCGTCCGGCCTTGCGGCCTTGCTCGATGCGGCGCCCGCCCCGGCGTGGCTG
CGCGGGGCGGATGGCGCGCTGTCTTATGTGAACCCCGCCTTCGTGGTGGCGGTGGGCGCCGCCTCGGCGGAGGAGGCCCG
CGCGCAGGGCCTCGACCTCCTTGACGGCAAGACGCGCGCTGCCGCCGCCAGCGCGGAAGGCGCGGACGGTCATTTCCGCC
AGCGGGTGAAGGCCGTCACCAAGGGCCAGCGGCGGCAGATGGAGGTGGTGGAGGTGGCCGGCATCTTCGGCACCGCCGGC
ATCGCCATCGATGTGACGTCGGAGGAAGACGCGCGGGCGGAGATGAAGCAGGCGGTGGTCGCCCATCGCCGCACCCTCGA
CCAATTGACCACGGCGGTGGCCATCTTCGGCGCCGACGAGCGCCTCGTGTTCCACAATGCCGCCTATGAGCGGCTGTTCG
ACCTCTCCCCCGCCTTTCTCGACCAGCACCCACCGGAAGGCGAGATCCTGGAAGACCTGCGCACCCGCCGCAAGGTGCCG
GAGCAGGCCGACTTCCGCGGCTGGCGCGCCCAGCTGCGCGAGGCCTACCGGGCCATCGAGCCGGTGAACGACTGGTGGCA
CCTGCCCGGCGGGCAGATGCTGCGGGTGGTGGTGACGCCCAATGCGGAAGGCGGCGTCACCTATCTGTTCGACGACCTCT
CCGAGCATATGGCGCTGGAGAGCCGCTACAACACGCTCATCCGCATCCAGGGCGAGACGCTGGACGGGCTGGCGGAAGCC
GTCGCCGTGTTCGGCTCGGACGGGCGGCTCAATCTTTACAACCACGCGTTCCTCGGCCTGTGGTCGCTCGAGGCTCGCGC
TTTGGGCGAGCGACCGCACGTGGATGCGGTGGCCGCCCTGTGCCGGCCGCTGCATGGCGAGACCTCGGCCTTCGCCCGCA
TCCGCCACGCGGTGACCACCATCGGCCCGCGCGAGGCGGTGACTTTGCGCATCGAGCGCCCGGACGGCCGGGTTCTGGAC
GGCGCCACCCAGCCGCTGCCGGACGGCGGCACCATGGTCACCTTCCGCGATGTCACCGACAGCGTGAAGGTGGAGCGGGC
GCTGATCGAGCGCGCCGAGGCGCTGGAGGCGGCGGACAAGCTGAAGAATGCCTTCGTCGGCCACGTCTCCTACCATTTGC
GCACGCCCCTCAACACGCTCCTGGGCTATGCCGACATGCTGCGGGATGGCCTAGCCGGCCCGCTCAATACCCGCCAGCAG
GATTATCTGGAGCACATGCGCCAGTCCTCCGACCAGCTGCGCGCGCTGATCGACGACATCCTCGACCTCGCCTCCATCGA
TGCCGGGGCCATGGAGCTGGACCTGTCCGACGTGGACGTGGGCGAGACCGTGCTCGGCGTCGCCGAGGCGGTGCGCGATC
CGGTGGCGGAGGCGGGGCTGAACCTTGCCGTCAGCGTCGGCCCGGATGCGGGCCATTTCGTCGCCGACGGGCGGCGGGTG
CGGCAGATCCTGTTCAACCTCCTGTCCAACGCCATCGCCGTCTCGCCCGCCGGCGGCACGGTGAGCCTCGGCGCGGTGCG
GCGCGACGGGGCGCTGGTCTTCACCGTGCGCGACGAGGGGCCGGGCGTGCCCGCCGAGGTGGCCGATACCCTGTTCGAGC
GCTTCGAGAGCCGCAGCGCCGGCCCGCGCCATCGCGGGGTGGGGCTGGGCCTTGCCATCGTGCGCTCCTTCATGACCCTC
CATGGCGGCTCCGTCACCGTGGCGCCGGCCGGGCGCGGGCCGGACGCCAAAGGTACCCTCGCCACCTGTATCTTCCCCTT
GTCCGGCGAAGGCCGGAGAGAGGCCGCCGAATGA

Upstream 100 bases:

>100_bases
TCAACGTCCGCTGCCCGTTCGGTAGACTGACGCGAGTGATTCGCGGGGGCGCCGGAGGAAGCTGCGGCGCCCGTCGGGCA
GGGGAAGGACACCGGGGCGA

Downstream 100 bases:

>100_bases
GCCTCGTGATCGAACGCCTTGCCGGCCAGCCCGTCGCCTGCCGTGTCGTGCTCCAGGATCTCGCGGCGACAGCCCGCCTC
GCCGGCTGGCTCTCCACCTG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 837; Mature: 836

Protein sequence:

>837_residues
MADRIRTGVPRQRRGREQGSAHRAVGLRRFSLPSCSVRPVCAGLAAVFLSSTLFVSPAAAGWDAAATAAGALWPVAGLAA
AAIAGLAAMRSHRVAKDLRGRIEAAERAAADAAASAARARAEAQACRVLLSDGAPAFLLWTGREAPADLFGRTPETLKAE
LGPASSAFETALARLKAEDGAFSQTLDTPRGPLRLDGRSRAGAGILLLAPLSSETSGHEAGPMASGLAALLDAAPAPAWL
RGADGALSYVNPAFVVAVGAASAEEARAQGLDLLDGKTRAAAASAEGADGHFRQRVKAVTKGQRRQMEVVEVAGIFGTAG
IAIDVTSEEDARAEMKQAVVAHRRTLDQLTTAVAIFGADERLVFHNAAYERLFDLSPAFLDQHPPEGEILEDLRTRRKVP
EQADFRGWRAQLREAYRAIEPVNDWWHLPGGQMLRVVVTPNAEGGVTYLFDDLSEHMALESRYNTLIRIQGETLDGLAEA
VAVFGSDGRLNLYNHAFLGLWSLEARALGERPHVDAVAALCRPLHGETSAFARIRHAVTTIGPREAVTLRIERPDGRVLD
GATQPLPDGGTMVTFRDVTDSVKVERALIERAEALEAADKLKNAFVGHVSYHLRTPLNTLLGYADMLRDGLAGPLNTRQQ
DYLEHMRQSSDQLRALIDDILDLASIDAGAMELDLSDVDVGETVLGVAEAVRDPVAEAGLNLAVSVGPDAGHFVADGRRV
RQILFNLLSNAIAVSPAGGTVSLGAVRRDGALVFTVRDEGPGVPAEVADTLFERFESRSAGPRHRGVGLGLAIVRSFMTL
HGGSVTVAPAGRGPDAKGTLATCIFPLSGEGRREAAE

Sequences:

>Translated_837_residues
MADRIRTGVPRQRRGREQGSAHRAVGLRRFSLPSCSVRPVCAGLAAVFLSSTLFVSPAAAGWDAAATAAGALWPVAGLAA
AAIAGLAAMRSHRVAKDLRGRIEAAERAAADAAASAARARAEAQACRVLLSDGAPAFLLWTGREAPADLFGRTPETLKAE
LGPASSAFETALARLKAEDGAFSQTLDTPRGPLRLDGRSRAGAGILLLAPLSSETSGHEAGPMASGLAALLDAAPAPAWL
RGADGALSYVNPAFVVAVGAASAEEARAQGLDLLDGKTRAAAASAEGADGHFRQRVKAVTKGQRRQMEVVEVAGIFGTAG
IAIDVTSEEDARAEMKQAVVAHRRTLDQLTTAVAIFGADERLVFHNAAYERLFDLSPAFLDQHPPEGEILEDLRTRRKVP
EQADFRGWRAQLREAYRAIEPVNDWWHLPGGQMLRVVVTPNAEGGVTYLFDDLSEHMALESRYNTLIRIQGETLDGLAEA
VAVFGSDGRLNLYNHAFLGLWSLEARALGERPHVDAVAALCRPLHGETSAFARIRHAVTTIGPREAVTLRIERPDGRVLD
GATQPLPDGGTMVTFRDVTDSVKVERALIERAEALEAADKLKNAFVGHVSYHLRTPLNTLLGYADMLRDGLAGPLNTRQQ
DYLEHMRQSSDQLRALIDDILDLASIDAGAMELDLSDVDVGETVLGVAEAVRDPVAEAGLNLAVSVGPDAGHFVADGRRV
RQILFNLLSNAIAVSPAGGTVSLGAVRRDGALVFTVRDEGPGVPAEVADTLFERFESRSAGPRHRGVGLGLAIVRSFMTL
HGGSVTVAPAGRGPDAKGTLATCIFPLSGEGRREAAE
>Mature_836_residues
ADRIRTGVPRQRRGREQGSAHRAVGLRRFSLPSCSVRPVCAGLAAVFLSSTLFVSPAAAGWDAAATAAGALWPVAGLAAA
AIAGLAAMRSHRVAKDLRGRIEAAERAAADAAASAARARAEAQACRVLLSDGAPAFLLWTGREAPADLFGRTPETLKAEL
GPASSAFETALARLKAEDGAFSQTLDTPRGPLRLDGRSRAGAGILLLAPLSSETSGHEAGPMASGLAALLDAAPAPAWLR
GADGALSYVNPAFVVAVGAASAEEARAQGLDLLDGKTRAAAASAEGADGHFRQRVKAVTKGQRRQMEVVEVAGIFGTAGI
AIDVTSEEDARAEMKQAVVAHRRTLDQLTTAVAIFGADERLVFHNAAYERLFDLSPAFLDQHPPEGEILEDLRTRRKVPE
QADFRGWRAQLREAYRAIEPVNDWWHLPGGQMLRVVVTPNAEGGVTYLFDDLSEHMALESRYNTLIRIQGETLDGLAEAV
AVFGSDGRLNLYNHAFLGLWSLEARALGERPHVDAVAALCRPLHGETSAFARIRHAVTTIGPREAVTLRIERPDGRVLDG
ATQPLPDGGTMVTFRDVTDSVKVERALIERAEALEAADKLKNAFVGHVSYHLRTPLNTLLGYADMLRDGLAGPLNTRQQD
YLEHMRQSSDQLRALIDDILDLASIDAGAMELDLSDVDVGETVLGVAEAVRDPVAEAGLNLAVSVGPDAGHFVADGRRVR
QILFNLLSNAIAVSPAGGTVSLGAVRRDGALVFTVRDEGPGVPAEVADTLFERFESRSAGPRHRGVGLGLAIVRSFMTLH
GGSVTVAPAGRGPDAKGTLATCIFPLSGEGRREAAE

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=287, Percent_Identity=30.3135888501742, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=32.7659574468085, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI48994928, Length=289, Percent_Identity=30.1038062283737, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=32.4324324324324, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1789149, Length=241, Percent_Identity=28.6307053941909, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=27.0916334661355, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790861, Length=274, Percent_Identity=28.4671532846715, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=279, Percent_Identity=27.5985663082437, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI87081816, Length=323, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790300, Length=275, Percent_Identity=27.6363636363636, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=25.3164556962025, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=258, Percent_Identity=25.968992248062, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788549, Length=265, Percent_Identity=23.7735849056604, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=279, Percent_Identity=28.3154121863799, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88590; Mature: 88459

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRIRTGVPRQRRGREQGSAHRAVGLRRFSLPSCSVRPVCAGLAAVFLSSTLFVSPAAA
CCCCCCCCCCHHHCCCCCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GWDAAATAAGALWPVAGLAAAAIAGLAAMRSHRVAKDLRGRIEAAERAAADAAASAARAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAQACRVLLSDGAPAFLLWTGREAPADLFGRTPETLKAELGPASSAFETALARLKAEDG
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHCCCC
AFSQTLDTPRGPLRLDGRSRAGAGILLLAPLSSETSGHEAGPMASGLAALLDAAPAPAWL
CHHHHCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCHHH
RGADGALSYVNPAFVVAVGAASAEEARAQGLDLLDGKTRAAAASAEGADGHFRQRVKAVT
CCCCCCHHHCCCEEEEEECCCCHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHH
KGQRRQMEVVEVAGIFGTAGIAIDVTSEEDARAEMKQAVVAHRRTLDQLTTAVAIFGADE
CCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
RLVFHNAAYERLFDLSPAFLDQHPPEGEILEDLRTRRKVPEQADFRGWRAQLREAYRAIE
EEEEHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
PVNDWWHLPGGQMLRVVVTPNAEGGVTYLFDDLSEHMALESRYNTLIRIQGETLDGLAEA
CCCHHEECCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHH
VAVFGSDGRLNLYNHAFLGLWSLEARALGERPHVDAVAALCRPLHGETSAFARIRHAVTT
HHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHC
IGPREAVTLRIERPDGRVLDGATQPLPDGGTMVTFRDVTDSVKVERALIERAEALEAADK
CCCCCEEEEEEECCCCCEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
LKNAFVGHVSYHLRTPLNTLLGYADMLRDGLAGPLNTRQQDYLEHMRQSSDQLRALIDDI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
LDLASIDAGAMELDLSDVDVGETVLGVAEAVRDPVAEAGLNLAVSVGPDAGHFVADGRRV
HHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCHHHHCCCEEEEEECCCCCCCHHCCHHH
RQILFNLLSNAIAVSPAGGTVSLGAVRRDGALVFTVRDEGPGVPAEVADTLFERFESRSA
HHHHHHHHHHHEEECCCCCEEEECEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCC
GPRHRGVGLGLAIVRSFMTLHGGSVTVAPAGRGPDAKGTLATCIFPLSGEGRREAAE
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ADRIRTGVPRQRRGREQGSAHRAVGLRRFSLPSCSVRPVCAGLAAVFLSSTLFVSPAAA
CCCCCCCCCHHHCCCCCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GWDAAATAAGALWPVAGLAAAAIAGLAAMRSHRVAKDLRGRIEAAERAAADAAASAARAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAQACRVLLSDGAPAFLLWTGREAPADLFGRTPETLKAELGPASSAFETALARLKAEDG
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHCCCC
AFSQTLDTPRGPLRLDGRSRAGAGILLLAPLSSETSGHEAGPMASGLAALLDAAPAPAWL
CHHHHCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCHHH
RGADGALSYVNPAFVVAVGAASAEEARAQGLDLLDGKTRAAAASAEGADGHFRQRVKAVT
CCCCCCHHHCCCEEEEEECCCCHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHH
KGQRRQMEVVEVAGIFGTAGIAIDVTSEEDARAEMKQAVVAHRRTLDQLTTAVAIFGADE
CCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
RLVFHNAAYERLFDLSPAFLDQHPPEGEILEDLRTRRKVPEQADFRGWRAQLREAYRAIE
EEEEHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
PVNDWWHLPGGQMLRVVVTPNAEGGVTYLFDDLSEHMALESRYNTLIRIQGETLDGLAEA
CCCHHEECCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHH
VAVFGSDGRLNLYNHAFLGLWSLEARALGERPHVDAVAALCRPLHGETSAFARIRHAVTT
HHHHCCCCCEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHC
IGPREAVTLRIERPDGRVLDGATQPLPDGGTMVTFRDVTDSVKVERALIERAEALEAADK
CCCCCEEEEEEECCCCCEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
LKNAFVGHVSYHLRTPLNTLLGYADMLRDGLAGPLNTRQQDYLEHMRQSSDQLRALIDDI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
LDLASIDAGAMELDLSDVDVGETVLGVAEAVRDPVAEAGLNLAVSVGPDAGHFVADGRRV
HHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCHHHHCCCEEEEEECCCCCCCHHCCHHH
RQILFNLLSNAIAVSPAGGTVSLGAVRRDGALVFTVRDEGPGVPAEVADTLFERFESRSA
HHHHHHHHHHHEEECCCCCEEEECEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCC
GPRHRGVGLGLAIVRSFMTLHGGSVTVAPAGRGPDAKGTLATCIFPLSGEGRREAAE
CCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]