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The map label for this gene is yedX [C]

Identifier: 154247219

GI number: 154247219

Start: 3654219

End: 3654572

Strand: Reverse

Name: yedX [C]

Synonym: Xaut_3291

Alternate gene names: 154247219

Gene position: 3654572-3654219 (Counterclockwise)

Preceding gene: 154247221

Following gene: 154247218

Centisome position: 68.84

GC content: 66.95

Gene sequence:

>354_bases
ATGGGGCGCCTGTCCACGCATGTACTCGATACCGTCGCCGGTGGTCCGGCGGCCAATGTGGCGGTTGAACTTTACCGTTT
GGCGCCAGATGGCACGCGCACGCTCCTGACCGAGCGCCGGACCAATGCGGACGGGCGCACCGACACGCCTTTGCTGGCGG
GCGATGAGTTCAAGGCCGGCACCTACGAGCTTCAGTTCCACATCGGCGCGCATTTCCGCGCCACCGGCGCGCCAGCCTCC
GATCCGCCCTTCCTCGATGTGGTGCCCCTGCGCTTCTCGCTGGCGGAGGACGGGCACTATCATGTGCCGCTGCTGTGCTC
CCCGTGGAGCTACTCCACCTATCGGGGCTCCTGA

Upstream 100 bases:

>100_bases
AATCGGAAGATCTTCCAATATTTTTGGGAAATGAATCGTCGGCGACCGGGTTATGCTGCCATGCAGCGGAGCTTTTGCCC
GCAAGGCTTGCGAGGGAAAA

Downstream 100 bases:

>100_bases
GCGATGAGCGTGCCCAACGATCCCATCACCGGCCGCCCCTACCCGCGCGACCTGATCGGCTACGGACGCAATCCGCCCCA
TGCGCGCTGGCCGGGAGAGG

Product: hydroxyisourate hydrolase

Products: NA

Alternate protein names: HIU hydrolase; HIUHase [H]

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MGRLSTHVLDTVAGGPAANVAVELYRLAPDGTRTLLTERRTNADGRTDTPLLAGDEFKAGTYELQFHIGAHFRATGAPAS
DPPFLDVVPLRFSLAEDGHYHVPLLCSPWSYSTYRGS

Sequences:

>Translated_117_residues
MGRLSTHVLDTVAGGPAANVAVELYRLAPDGTRTLLTERRTNADGRTDTPLLAGDEFKAGTYELQFHIGAHFRATGAPAS
DPPFLDVVPLRFSLAEDGHYHVPLLCSPWSYSTYRGS
>Mature_116_residues
GRLSTHVLDTVAGGPAANVAVELYRLAPDGTRTLLTERRTNADGRTDTPLLAGDEFKAGTYELQFHIGAHFRATGAPASD
PPFLDVVPLRFSLAEDGHYHVPLLCSPWSYSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=115, Percent_Identity=37.3913043478261, Blast_Score=67, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24652571, Length=115, Percent_Identity=39.1304347826087, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 12671; Mature: 12540

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00768 TRANSTHYRETIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLSTHVLDTVAGGPAANVAVELYRLAPDGTRTLLTERRTNADGRTDTPLLAGDEFKAG
CCCCHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEECCCCCCC
TYELQFHIGAHFRATGAPASDPPFLDVVPLRFSLAEDGHYHVPLLCSPWSYSTYRGS
EEEEEEEECCEEEECCCCCCCCCEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
GRLSTHVLDTVAGGPAANVAVELYRLAPDGTRTLLTERRTNADGRTDTPLLAGDEFKAG
CCCHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEECCCCCCC
TYELQFHIGAHFRATGAPASDPPFLDVVPLRFSLAEDGHYHVPLLCSPWSYSTYRGS
EEEEEEEECCEEEECCCCCCCCCEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]