Click here to switch to the map view.

The map label for this gene is cobJ [H]

Identifier: 154247210

GI number: 154247210

Start: 3642628

End: 3643476

Strand: Reverse

Name: cobJ [H]

Synonym: Xaut_3282

Alternate gene names: 154247210

Gene position: 3643476-3642628 (Counterclockwise)

Preceding gene: 154247211

Following gene: 154247208

Centisome position: 68.63

GC content: 74.09

Gene sequence:

>849_bases
ATGACTGGCGGCGACCGGCGCGGGCGCATCACCGTGGTGGGCCTCGGCCCCGGTGCGGCCCGGCAGATGACGCCTGAAGC
GGCGGCGGCGGTGGAAGCGGCGGACCTGGTCTTCGGCTATGCCCCCTACCTCGCCCGCCTGCCGGAGCGGCCCGGGCAGG
AGCGCCGGCCTTCAGACAATCGCGAGGAGATCGCCCGTGCCTCGGCCGCGCTGGATGCGGCCGTTGCCGGCGCGCGGGTC
GCCATGGTGTCGGGGGGCGATCCCGGCGTGTTCGCCATGGCCGCCGCTGTGTGCGAGGCCATCGAGCACGGGCCGGAGGC
GTGGCGCGCCCTCGATTTCGAGGTGGTGCCCGGCGTCACCGCCATGCTGGCGGTCGCGGCGCGCTGCGGGGCGCCGCTGG
GCCACGATTTCTGCGCCCTCTCGCTCTCCGACAATCTGAAGCCCTGGGCGCTGGTGGAAAAGCGCCTGCTGCTGGCGGCG
GAGGCCGGCTTCGTCATCGCCCTCTACAATCCCATCAGCCGGGCGCGGCCGTGGCAGCTGGGACGGGCCTTCGCGCTGCT
GCGCGAGCGCCTTGCGGGCAACGTGCCGGTGGTGTTCGGCCGCGCGGCGGGACGCGAGGACGAGCGCATCACCCTCGCCA
CCCTGGCCGAGGCCGACCCGGCGCAGGCTGACATGGCCACCTGCGTGATTATCGGCACCACCGACACCCGCATCGTGCCG
CGTCCCGGCCTGCCGCCTTTGGTCTACGCACCCCGCTCGGCGGACAGGCCCGCGCCACGAGCGGAAGGAGAGTCCGCGCC
GCGAGCGGGAGAAGAGCCCGTGTCTCCAGTGGAGGAATCCGCGCCGTGA

Upstream 100 bases:

>100_bases
GCACCATGGCCGATTGCGCCCTGGTTCCCTTGGCCGAACGGGCGGACGAGCGCGCGCCCTATTTCTCCATTGTGCTGGTG
CCCGGCTGGGAGCGCGCGGC

Downstream 100 bases:

>100_bases
GCGCCGAGCCGGTCGAGCAGCCATGCCTCGGCTTCCGCCGGCGTCTCCACCGCCGGGACGGCGGGAATGGCGGGCCGCGC
GATCAGCAGCACCTCGATGC

Product: precorrin-3B C17-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTGGDRRGRITVVGLGPGAARQMTPEAAAAVEAADLVFGYAPYLARLPERPGQERRPSDNREEIARASAALDAAVAGARV
AMVSGGDPGVFAMAAAVCEAIEHGPEAWRALDFEVVPGVTAMLAVAARCGAPLGHDFCALSLSDNLKPWALVEKRLLLAA
EAGFVIALYNPISRARPWQLGRAFALLRERLAGNVPVVFGRAAGREDERITLATLAEADPAQADMATCVIIGTTDTRIVP
RPGLPPLVYAPRSADRPAPRAEGESAPRAGEEPVSPVEESAP

Sequences:

>Translated_282_residues
MTGGDRRGRITVVGLGPGAARQMTPEAAAAVEAADLVFGYAPYLARLPERPGQERRPSDNREEIARASAALDAAVAGARV
AMVSGGDPGVFAMAAAVCEAIEHGPEAWRALDFEVVPGVTAMLAVAARCGAPLGHDFCALSLSDNLKPWALVEKRLLLAA
EAGFVIALYNPISRARPWQLGRAFALLRERLAGNVPVVFGRAAGREDERITLATLAEADPAQADMATCVIIGTTDTRIVP
RPGLPPLVYAPRSADRPAPRAEGESAPRAGEEPVSPVEESAP
>Mature_281_residues
TGGDRRGRITVVGLGPGAARQMTPEAAAAVEAADLVFGYAPYLARLPERPGQERRPSDNREEIARASAALDAAVAGARVA
MVSGGDPGVFAMAAAVCEAIEHGPEAWRALDFEVVPGVTAMLAVAARCGAPLGHDFCALSLSDNLKPWALVEKRLLLAAE
AGFVIALYNPISRARPWQLGRAFALLRERLAGNVPVVFGRAAGREDERITLATLAEADPAQADMATCVIIGTTDTRIVPR
PGLPPLVYAPRSADRPAPRAEGESAPRAGEEPVSPVEESAP

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 29497; Mature: 29366

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGDRRGRITVVGLGPGAARQMTPEAAAAVEAADLVFGYAPYLARLPERPGQERRPSDN
CCCCCCCCEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
REEIARASAALDAAVAGARVAMVSGGDPGVFAMAAAVCEAIEHGPEAWRALDFEVVPGVT
HHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHEECEEHHCCHH
AMLAVAARCGAPLGHDFCALSLSDNLKPWALVEKRLLLAAEAGFVIALYNPISRARPWQL
HHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHEECCCEEEEEECCHHHCCCHHH
GRAFALLRERLAGNVPVVFGRAAGREDERITLATLAEADPAQADMATCVIIGTTDTRIVP
HHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCEEEC
RPGLPPLVYAPRSADRPAPRAEGESAPRAGEEPVSPVEESAP
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
TGGDRRGRITVVGLGPGAARQMTPEAAAAVEAADLVFGYAPYLARLPERPGQERRPSDN
CCCCCCCEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
REEIARASAALDAAVAGARVAMVSGGDPGVFAMAAAVCEAIEHGPEAWRALDFEVVPGVT
HHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHEECEEHHCCHH
AMLAVAARCGAPLGHDFCALSLSDNLKPWALVEKRLLLAAEAGFVIALYNPISRARPWQL
HHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHEECCCEEEEEECCHHHCCCHHH
GRAFALLRERLAGNVPVVFGRAAGREDERITLATLAEADPAQADMATCVIIGTTDTRIVP
HHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCEEEC
RPGLPPLVYAPRSADRPAPRAEGESAPRAGEEPVSPVEESAP
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]