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The map label for this gene is cobL [H]

Identifier: 154247208

GI number: 154247208

Start: 3640570

End: 3641832

Strand: Reverse

Name: cobL [H]

Synonym: Xaut_3280

Alternate gene names: 154247208

Gene position: 3641832-3640570 (Counterclockwise)

Preceding gene: 154247210

Following gene: 154247207

Centisome position: 68.6

GC content: 73.08

Gene sequence:

>1263_bases
ATGGCGGGCATAAGTGCCCCAGCGGGGCGCTGGCTGTCCATCGTCGGCATCGGCGAGGATGGGGCGGACGGTCTCTCCCC
CGCCGCGCGCGCCGCCATTTCCTCCGCCGAAATCGTGTTTGGCGGGGCGCGCCACCTTGCGCTCGCGGGCGGGCTCGTCA
CCGGAGAAGCGCAGGTGTGGCCGAGCCCCTTCAGCCTTGTCGGCGTTCTCGCCGCGCGCGGGCGGGCGGTGTGCGTCCTC
GCCTCGGGCGATCCCTTCCTTTACGGCGTGGGCGCGAGCCTCGCCCGCCATGTGCCGGCCGACGAGATGCGCGCCTTCCC
CGCGCCTTCCGCCTTCGCGCTGGCCGCCGCGCGCCTTGGCTGGCCGTTGCAGGAGGCGGACCTCGTATCCCTCCACGGCC
GGCCGCTGGCCCGGCTGCGGCCCTTCCTGCAGGACGGCGCGCGGCTGATCCTCCTCACCTCGGACGGCGACGGGCCGCGA
CAGGTGGCGGATTTCGTCACCGCCCACGGCTGCGGTGCTTCGCGCCTTATGGTGCTGGAGGCGCTGGGCGGCCCCTCCGA
GCGGGTGCGCGAGACGCGGGCCGAGGCCTTCGCCTTTACCGACGTGACCGCGCTGAACGTGGTGGCGCTGCAGGTGGCGG
CGGAGGCAAACGCCCCCCTCCTGCCTCTCGCCAGCGGCCTTGCCGACGACTTGTTCGAGCATGATGGCCAGATCACCAAG
CGCGAGATCCGCGCCCTCACCCTCTCCTCCCTCGCGCCACGACGGGGGGAGCTGTTGTGGGATATCGGCGCGGGGGCTGG
GTCCATCGCCATCGAATGGCTGCTGGCGCATCCCTCCCTCAGTGCCGTCGCCATCGAGGGGCATGCGGAGCGCGCCGCCC
GCGTCGGCCGCAATGCCGGGCGCCTCGGCGTGCCGCATCTGAAAGTCGTAGAGGGTGCGGCACCCGGCGCCCTTGCCGGA
CTGCCCCCGCCGGATGTCATCTTTCTCGGCGGCGGCGCCTCGGAGCCGGGCGTGTTCGAGGCGGCGATGGCGGCGCTGAA
GCCGGGCGGGCGGCTGGTGGCCAACGCGGTGACGCTGGAGACGGAAGCGGTGCTCCTCGCTGCCCATGCAAGGCTCGGCG
GCGATCTCGTACGCATCGCGCTGGCGCGCTCCGTGGCGGTGAAGGGCATGACCGGCTGGCGGCCCGCCATGCCGGTCACC
CAATGGCGCTATGGCAAGCCGCCCGAAGGCAAGCCACCTGAGACCGAGGGAGGCGGGGCATGA

Upstream 100 bases:

>100_bases
AAGCCGCCTCGCGAGGGCACTGGCCTCGCTGGTGCCGCCCAGCAGGAGAATGCGCGGAACCATGGCTGAAACGGCGCGGG
TCGAGACGGAGGGATCGCTC

Downstream 100 bases:

>100_bases
TCGTGGCCGGCATCGGCTCGAAGCGGGGCGTGAGCGTGGATGAGGTGCTGGCCGCCTTCGACGCGGCCCTGGCGCGCGCC
GCGCTGGCACGGGACGACGT

Product: precorrin-6y C5,15-methyltransferase subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MAGISAPAGRWLSIVGIGEDGADGLSPAARAAISSAEIVFGGARHLALAGGLVTGEAQVWPSPFSLVGVLAARGRAVCVL
ASGDPFLYGVGASLARHVPADEMRAFPAPSAFALAAARLGWPLQEADLVSLHGRPLARLRPFLQDGARLILLTSDGDGPR
QVADFVTAHGCGASRLMVLEALGGPSERVRETRAEAFAFTDVTALNVVALQVAAEANAPLLPLASGLADDLFEHDGQITK
REIRALTLSSLAPRRGELLWDIGAGAGSIAIEWLLAHPSLSAVAIEGHAERAARVGRNAGRLGVPHLKVVEGAAPGALAG
LPPPDVIFLGGGASEPGVFEAAMAALKPGGRLVANAVTLETEAVLLAAHARLGGDLVRIALARSVAVKGMTGWRPAMPVT
QWRYGKPPEGKPPETEGGGA

Sequences:

>Translated_420_residues
MAGISAPAGRWLSIVGIGEDGADGLSPAARAAISSAEIVFGGARHLALAGGLVTGEAQVWPSPFSLVGVLAARGRAVCVL
ASGDPFLYGVGASLARHVPADEMRAFPAPSAFALAAARLGWPLQEADLVSLHGRPLARLRPFLQDGARLILLTSDGDGPR
QVADFVTAHGCGASRLMVLEALGGPSERVRETRAEAFAFTDVTALNVVALQVAAEANAPLLPLASGLADDLFEHDGQITK
REIRALTLSSLAPRRGELLWDIGAGAGSIAIEWLLAHPSLSAVAIEGHAERAARVGRNAGRLGVPHLKVVEGAAPGALAG
LPPPDVIFLGGGASEPGVFEAAMAALKPGGRLVANAVTLETEAVLLAAHARLGGDLVRIALARSVAVKGMTGWRPAMPVT
QWRYGKPPEGKPPETEGGGA
>Mature_419_residues
AGISAPAGRWLSIVGIGEDGADGLSPAARAAISSAEIVFGGARHLALAGGLVTGEAQVWPSPFSLVGVLAARGRAVCVLA
SGDPFLYGVGASLARHVPADEMRAFPAPSAFALAAARLGWPLQEADLVSLHGRPLARLRPFLQDGARLILLTSDGDGPRQ
VADFVTAHGCGASRLMVLEALGGPSERVRETRAEAFAFTDVTALNVVALQVAAEANAPLLPLASGLADDLFEHDGQITKR
EIRALTLSSLAPRRGELLWDIGAGAGSIAIEWLLAHPSLSAVAIEGHAERAARVGRNAGRLGVPHLKVVEGAAPGALAGL
PPPDVIFLGGGASEPGVFEAAMAALKPGGRLVANAVTLETEAVLLAAHARLGGDLVRIALARSVAVKGMTGWRPAMPVTQ
WRYGKPPEGKPPETEGGGA

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 42927; Mature: 42796

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGISAPAGRWLSIVGIGEDGADGLSPAARAAISSAEIVFGGARHLALAGGLVTGEAQVW
CCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCEEEECCCCEEEEECCEEECCCEEC
PSPFSLVGVLAARGRAVCVLASGDPFLYGVGASLARHVPADEMRAFPAPSAFALAAARLG
CCHHHHHHHHHCCCCEEEEEECCCCEEEECCHHHHHCCCHHHHHCCCCCHHHHHHHHHHC
WPLQEADLVSLHGRPLARLRPFLQDGARLILLTSDGDGPRQVADFVTAHGCGASRLMVLE
CCCCCCCEEEECCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHEEEEE
ALGGPSERVRETRAEAFAFTDVTALNVVALQVAAEANAPLLPLASGLADDLFEHDGQITK
CCCCCHHHHHHHHHHHHEEHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHH
REIRALTLSSLAPRRGELLWDIGAGAGSIAIEWLLAHPSLSAVAIEGHAERAARVGRNAG
HHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCEEEEECCCHHHHHHHCCCCC
RLGVPHLKVVEGAAPGALAGLPPPDVIFLGGGASEPGVFEAAMAALKPGGRLVANAVTLE
CCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEEEEE
TEAVLLAAHARLGGDLVRIALARSVAVKGMTGWRPAMPVTQWRYGKPPEGKPPETEGGGA
HHEEEEEHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AGISAPAGRWLSIVGIGEDGADGLSPAARAAISSAEIVFGGARHLALAGGLVTGEAQVW
CCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCEEEECCCCEEEEECCEEECCCEEC
PSPFSLVGVLAARGRAVCVLASGDPFLYGVGASLARHVPADEMRAFPAPSAFALAAARLG
CCHHHHHHHHHCCCCEEEEEECCCCEEEECCHHHHHCCCHHHHHCCCCCHHHHHHHHHHC
WPLQEADLVSLHGRPLARLRPFLQDGARLILLTSDGDGPRQVADFVTAHGCGASRLMVLE
CCCCCCCEEEECCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHEEEEE
ALGGPSERVRETRAEAFAFTDVTALNVVALQVAAEANAPLLPLASGLADDLFEHDGQITK
CCCCCHHHHHHHHHHHHEEHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHH
REIRALTLSSLAPRRGELLWDIGAGAGSIAIEWLLAHPSLSAVAIEGHAERAARVGRNAG
HHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCEEEEECCCHHHHHHHCCCCC
RLGVPHLKVVEGAAPGALAGLPPPDVIFLGGGASEPGVFEAAMAALKPGGRLVANAVTLE
CCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEEEEE
TEAVLLAAHARLGGDLVRIALARSVAVKGMTGWRPAMPVTQWRYGKPPEGKPPETEGGGA
HHEEEEEHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]