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The map label for this gene is cpx [H]

Identifier: 154247162

GI number: 154247162

Start: 3585052

End: 3586785

Strand: Reverse

Name: cpx [H]

Synonym: Xaut_3234

Alternate gene names: 154247162

Gene position: 3586785-3585052 (Counterclockwise)

Preceding gene: 154247163

Following gene: 154247160

Centisome position: 67.56

GC content: 71.11

Gene sequence:

>1734_bases
ATGAGTCTGCGCTACGACCTGCAATCGCACCCGCCGCTGGCAGTGCTCGCCGCCTCCATCGCCCAGCACATGGGGCTGAT
GGCGGTGACGCTGGTGTTCCCGGTGCTGGTGGCGCAAGCCGCCGGCGCGGATGCGGCGACACAGGCCAATTACCTTGCGC
TGGCCATGCTCGCCATGGGCCTGTCCACCCTGTTCCAGTCCTGGGGCGGCCGGCTGCCGGGGCTGCCGCGGGTCGGCAGC
GGCTTCCTGCTGCCGGCGGTGTTCACCGCCGCCTATTTGCCCGCCGCACTGCTCACCGCCAAGACCGGCGGGCTTCCGGC
GGTGGCCGGCCTCACCATCGCGGCGGGGCTGACCCAGATCACCCTCAGCCGCTTCATCAGCCGGCTGCGGCCGTACCTGC
CCATCGAGATCGTCGGGCTGGTGGTGCTTTTGATCGGCATCATACTGGGGGTGGTGGCGTTCAAGCTGGTGGTGGGACTG
GGGCAGGAGCGGCCCCTGTCGGGCGACGGCACCGGCGCCGCCGTGCTGGCGCTGGCGGTCATGATCGGCCTTGCGGTGTG
GGGCACCGCCCGGCTCAAGACCATGGCGGTGCTGGTGGGCCTTGCGGTGGGAACCGCCTTCCATGTGGCGTGGAGGCTCG
CCGACCCCTCCGGCATGTCTGCGGCCGATGCGGTGCCGGTGACCGCCCTTATGCCCTCGTTCGCCAGCTCGCTCGGCTGG
TCGCTGAACTGGCCGCTGGTGACGCCGAGCTTCAGCCTCGGCCTGCTGCCGGGCTTCCTGGCGGGGGCGCTGGCCTGCAC
CCTGCGCGGCTTCGGCGACATGGTGGCGAGCCAGCGGGCCAACGACCGTGACTGGAAGCGGCCGGACTATGCCAACATCG
AGGCCGGCGTGCTCGCCGACGGACTCGGCACGCTCATGGCCGGCCTGCTCGGCACCATGGGGCTGAACACCTATTCCGCC
AGCGTCGGGCTTTCGGTGGCGACGCAGGTGCTGGCGCGCCGGGTGGCCCTGGGCGTGGGCTTCGCCTGGATCGCCCTCGC
CTTCCTGCCCGGCGCATCGGCGCTGGTGCTGGCCATTCCGCGCGGGGTGCTGGGGGCGGCGCTGCTGTTCGCCTCCGCCT
TCATCGTGCTGTCCGGCGTGTCGATCCTCGGCCAGAGGATGCTCGATGCGCGGCGGACCATCACGGTGGGCCTCGGCTTC
CTGCTGGGCCTGTCGTTCGACCAGTTGCCGGCCTTCTATTCCCAGCATCTGTCGTCCGAATTGCAGTCCGTGGTCAGCTC
CTCGCTGATCCTCGGCCTGTTCACGGCGCTGGCGCTGAATGCCCTGTTCCGCATCGGCCGGCGCACCACGCTCCGGACGC
ACTGGGAGCCCGGGACCGGATTTTCAACCCTGCGTCCCTTCCTGCTGGACACCGGCGGCGTGGAAGGCGCCCGCGCCGAT
GCCGTCGCCCGCCTGGTGCAGCTGGCGGAAGAATTCAGCACCAGTGCCCCCGCCCTTGTCGAGGGGGCGGTGGAGGTGGC
GGCGACCTTCGACGAGCACCAGCTGAAACTGGCCTTCACCTGGGCCGGCCGGCCCCTGGAGGCGGGCCCCGCTCCCAGCC
TGGACCCGGAGGTGGACGAGGACGCGGTGATGAACGGCATCGTCCTGCGGCTGATGACCCGCCTGTCGGACCGCCTCACC
CGCCGGGTGCTGGCGGACGGCCGGCACGAGCTGGTGTGCGTGGTGGACCAGTAG

Upstream 100 bases:

>100_bases
GTCCGGCTTACCCGGGGCCGGGCCGATCCATGATCCCTCCCACCAGCTTTGTCACCGTCGCGCGGCGCGCGGCTCCTCCC
GCCCACAGGCGGGGGGCGGC

Downstream 100 bases:

>100_bases
GACCTCGCAAAAAGGGGCGGCACCCGCGCGCCGCCCCCTCATTTCACGCCGCGAGCCCTCGGGCCAGCTCCATGGCCTGC
CGCTCGAACAGGCGGCGATA

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 576

Protein sequence:

>577_residues
MSLRYDLQSHPPLAVLAASIAQHMGLMAVTLVFPVLVAQAAGADAATQANYLALAMLAMGLSTLFQSWGGRLPGLPRVGS
GFLLPAVFTAAYLPAALLTAKTGGLPAVAGLTIAAGLTQITLSRFISRLRPYLPIEIVGLVVLLIGIILGVVAFKLVVGL
GQERPLSGDGTGAAVLALAVMIGLAVWGTARLKTMAVLVGLAVGTAFHVAWRLADPSGMSAADAVPVTALMPSFASSLGW
SLNWPLVTPSFSLGLLPGFLAGALACTLRGFGDMVASQRANDRDWKRPDYANIEAGVLADGLGTLMAGLLGTMGLNTYSA
SVGLSVATQVLARRVALGVGFAWIALAFLPGASALVLAIPRGVLGAALLFASAFIVLSGVSILGQRMLDARRTITVGLGF
LLGLSFDQLPAFYSQHLSSELQSVVSSSLILGLFTALALNALFRIGRRTTLRTHWEPGTGFSTLRPFLLDTGGVEGARAD
AVARLVQLAEEFSTSAPALVEGAVEVAATFDEHQLKLAFTWAGRPLEAGPAPSLDPEVDEDAVMNGIVLRLMTRLSDRLT
RRVLADGRHELVCVVDQ

Sequences:

>Translated_577_residues
MSLRYDLQSHPPLAVLAASIAQHMGLMAVTLVFPVLVAQAAGADAATQANYLALAMLAMGLSTLFQSWGGRLPGLPRVGS
GFLLPAVFTAAYLPAALLTAKTGGLPAVAGLTIAAGLTQITLSRFISRLRPYLPIEIVGLVVLLIGIILGVVAFKLVVGL
GQERPLSGDGTGAAVLALAVMIGLAVWGTARLKTMAVLVGLAVGTAFHVAWRLADPSGMSAADAVPVTALMPSFASSLGW
SLNWPLVTPSFSLGLLPGFLAGALACTLRGFGDMVASQRANDRDWKRPDYANIEAGVLADGLGTLMAGLLGTMGLNTYSA
SVGLSVATQVLARRVALGVGFAWIALAFLPGASALVLAIPRGVLGAALLFASAFIVLSGVSILGQRMLDARRTITVGLGF
LLGLSFDQLPAFYSQHLSSELQSVVSSSLILGLFTALALNALFRIGRRTTLRTHWEPGTGFSTLRPFLLDTGGVEGARAD
AVARLVQLAEEFSTSAPALVEGAVEVAATFDEHQLKLAFTWAGRPLEAGPAPSLDPEVDEDAVMNGIVLRLMTRLSDRLT
RRVLADGRHELVCVVDQ
>Mature_576_residues
SLRYDLQSHPPLAVLAASIAQHMGLMAVTLVFPVLVAQAAGADAATQANYLALAMLAMGLSTLFQSWGGRLPGLPRVGSG
FLLPAVFTAAYLPAALLTAKTGGLPAVAGLTIAAGLTQITLSRFISRLRPYLPIEIVGLVVLLIGIILGVVAFKLVVGLG
QERPLSGDGTGAAVLALAVMIGLAVWGTARLKTMAVLVGLAVGTAFHVAWRLADPSGMSAADAVPVTALMPSFASSLGWS
LNWPLVTPSFSLGLLPGFLAGALACTLRGFGDMVASQRANDRDWKRPDYANIEAGVLADGLGTLMAGLLGTMGLNTYSAS
VGLSVATQVLARRVALGVGFAWIALAFLPGASALVLAIPRGVLGAALLFASAFIVLSGVSILGQRMLDARRTITVGLGFL
LGLSFDQLPAFYSQHLSSELQSVVSSSLILGLFTALALNALFRIGRRTTLRTHWEPGTGFSTLRPFLLDTGGVEGARADA
VARLVQLAEEFSTSAPALVEGAVEVAATFDEHQLKLAFTWAGRPLEAGPAPSLDPEVDEDAVMNGIVLRLMTRLSDRLTR
RVLADGRHELVCVVDQ

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790087, Length=464, Percent_Identity=26.9396551724138, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87082181, Length=437, Percent_Identity=26.7734553775744, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082178, Length=469, Percent_Identity=25.1599147121535, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 60044; Mature: 59913

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure 
SLRYDLQSHPPLAVLAASIAQHMGLMAVTLVFPVLVAQAAGADAATQANYLALAMLAMG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11792842; 8162194 [H]