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The map label for this gene is pcrA [H]

Identifier: 154246977

GI number: 154246977

Start: 3386410

End: 3388236

Strand: Direct

Name: pcrA [H]

Synonym: Xaut_3048

Alternate gene names: 154246977

Gene position: 3386410-3388236 (Clockwise)

Preceding gene: 154246976

Following gene: 154246978

Centisome position: 63.79

GC content: 58.07

Gene sequence:

>1827_bases
GTGGTCGACCTAACAGAAGCGCAGAAGGAAATTCTACAAGCTGTCGGGCATCAACTCGTCACCGGCGGTCCCGGTTCGGG
GAAGACTACCGTCTCTATCCTCAAAGCGGCCAAGATCGCGCGGGAGGAATTGAAGCCAGGACAGCGCATCCTTTTCCTCA
GCTTCGCGCGTGCAACCGTTTCGCGCGTGCTGGAGGCAATCGACGAAGAAAGCGCAATCACGCGAGAGGAGAGGCAACGG
ATCGAGGTCGATACCTACCATTCGTTCTTCTGGCGCATCCTTAAAACGCACGGCTACCTTGTCGGCTTTCCACGACGGAT
GACGATCCTCACGCCTCCGAATGAGGCGATTGCATTGTCGGCGGTTCGAAGCGGCTACAAGGCGGCCAAAAATCTGTCGG
ACGAGGAAAAGGCTGAGAAGCGCGCGAAGGAGGAAGCGGAGCGTGTCCGGCTGGCGACCGAAGAAGGGAAGGTCTGCTTC
GACCTCTTCGCAGACCGCGTGGCGACCCTGCTTCATGGCTCAGATAAGGTTCGAGCGCTCGTCTCTACGATGTATCCGTA
CATTACCCTGGACGAGTTTCAGGACACCAGCGCCGATCAATGGCGAGTGGTCCAAGCCCTCGGCGCCAACAGCACGTTGA
TCGCTCTTGCCGACCCGGAGCAGCGCATATTCGATTTCATCGGCGCCGATCCGGAAAGGCTGAACCACTTCAAGGCCGAT
TTCGCGCCGACGGTCCACGACCTTGCCGGTGACAACCATCGGAGCAAGGGGACGGAGATTGCCCTATTCGGCAACGACAT
CCTGACCGGCAATTTTCGGCAGAAGGAATACCAGGGTATCGGCTACGCGCCGTTCGCGTCGAACCCCAACCAAGCTTATG
CTTCACTGGTTGGCCAGGTGTTGCAAGCCCGGAAGCGCTTGGTTGAGTCTGGCCGGCGTGACTGGTCGTTGGCCATTCTC
GTGCCGACCAAGAAAATGACGCGGATGGTGTCTGACATCCTGCGCGAGCCATTCGGTAATGTTCCGTCGATTTCTCACTC
AGCAGCAGTTGATATGGAAGGCCCGATCCTCGCCGCAGAGATCATTGCTTTCCTGCTCCAAAAGTGCGGGCATGACGGAA
GTTTCGACGAATTTGTCGAGTTGATGTGCAGCTATTTTCACGGTCGAGGAGGCACGGCGCCGACCAAGGGCGACATGGAC
GAGGCTGCGCGGTTCCGGAAGGCGCTGTCCAAGTGGAACGAATGTCTAGCGAAAGGACGAACAACGCCTGGTAACAGCGT
CTTGCAAGGAACCTTTGCCGTGCACCAGGCAACTGCCGCACTGACATTCACAGGTGATCCGGATGCAGATTGGGTCTCGG
TGCGCGACGTTCTGGATACTGGGGCCTGTGAGCGACTGAAGGATGTCGCAAAGGACGTCCGTAACGTGCGTCTGCTTGAG
CGCGGTACGCAGCTCCGTCAGGGGTTGGCGCAGGACTGGCGTGACGTCGGCCGCTATAGCAACGCCCTTGCGATCACCCG
CCAGTCGTTTGTTCAGGAGCATTTCGCAACAGCCCACAAGCCTGAATCCGGCGTCGTGGTGATGAACATGCACAAGGCGA
AGGGAAAGCAGTTCGACGAGGTTGTGATCTTTGAAGGATGGCCAAAACGGTTCAAGGGCGAAATCGTGGCCAATCCTGAC
CGGATCGTCTTCGGCAATGTCCACGACGGGGTGATGACTCAGGCGCGTCAGAATTTTCGGGTCAGCATCACGCGCGCAAA
GGCACGCACGACGATCATGACACCAAGGGATGATGTCTGTGTTTTGCTCAGACCCGTACCGGCATGA

Upstream 100 bases:

>100_bases
TGCCTGCGTCACCCTGAAGGCACTGTGTGATCCGCCTCTACAGCCAGCCGAGCCCGAACCCGAAGACGATTTTGCTGACC
TGTTAGGATAGGCGATTACT

Downstream 100 bases:

>100_bases
CTCAAGCCTCTGGGTATGAAGGATGACGACATCTTCTGATCATCTGGAGTCCATGGCGCAGACGCTAGAGGCTACCGGGG
ATTATCGCGTCATCCGGCGT

Product: UvrD/REP helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MVDLTEAQKEILQAVGHQLVTGGPGSGKTTVSILKAAKIAREELKPGQRILFLSFARATVSRVLEAIDEESAITREERQR
IEVDTYHSFFWRILKTHGYLVGFPRRMTILTPPNEAIALSAVRSGYKAAKNLSDEEKAEKRAKEEAERVRLATEEGKVCF
DLFADRVATLLHGSDKVRALVSTMYPYITLDEFQDTSADQWRVVQALGANSTLIALADPEQRIFDFIGADPERLNHFKAD
FAPTVHDLAGDNHRSKGTEIALFGNDILTGNFRQKEYQGIGYAPFASNPNQAYASLVGQVLQARKRLVESGRRDWSLAIL
VPTKKMTRMVSDILREPFGNVPSISHSAAVDMEGPILAAEIIAFLLQKCGHDGSFDEFVELMCSYFHGRGGTAPTKGDMD
EAARFRKALSKWNECLAKGRTTPGNSVLQGTFAVHQATAALTFTGDPDADWVSVRDVLDTGACERLKDVAKDVRNVRLLE
RGTQLRQGLAQDWRDVGRYSNALAITRQSFVQEHFATAHKPESGVVVMNMHKAKGKQFDEVVIFEGWPKRFKGEIVANPD
RIVFGNVHDGVMTQARQNFRVSITRAKARTTIMTPRDDVCVLLRPVPA

Sequences:

>Translated_608_residues
MVDLTEAQKEILQAVGHQLVTGGPGSGKTTVSILKAAKIAREELKPGQRILFLSFARATVSRVLEAIDEESAITREERQR
IEVDTYHSFFWRILKTHGYLVGFPRRMTILTPPNEAIALSAVRSGYKAAKNLSDEEKAEKRAKEEAERVRLATEEGKVCF
DLFADRVATLLHGSDKVRALVSTMYPYITLDEFQDTSADQWRVVQALGANSTLIALADPEQRIFDFIGADPERLNHFKAD
FAPTVHDLAGDNHRSKGTEIALFGNDILTGNFRQKEYQGIGYAPFASNPNQAYASLVGQVLQARKRLVESGRRDWSLAIL
VPTKKMTRMVSDILREPFGNVPSISHSAAVDMEGPILAAEIIAFLLQKCGHDGSFDEFVELMCSYFHGRGGTAPTKGDMD
EAARFRKALSKWNECLAKGRTTPGNSVLQGTFAVHQATAALTFTGDPDADWVSVRDVLDTGACERLKDVAKDVRNVRLLE
RGTQLRQGLAQDWRDVGRYSNALAITRQSFVQEHFATAHKPESGVVVMNMHKAKGKQFDEVVIFEGWPKRFKGEIVANPD
RIVFGNVHDGVMTQARQNFRVSITRAKARTTIMTPRDDVCVLLRPVPA
>Mature_608_residues
MVDLTEAQKEILQAVGHQLVTGGPGSGKTTVSILKAAKIAREELKPGQRILFLSFARATVSRVLEAIDEESAITREERQR
IEVDTYHSFFWRILKTHGYLVGFPRRMTILTPPNEAIALSAVRSGYKAAKNLSDEEKAEKRAKEEAERVRLATEEGKVCF
DLFADRVATLLHGSDKVRALVSTMYPYITLDEFQDTSADQWRVVQALGANSTLIALADPEQRIFDFIGADPERLNHFKAD
FAPTVHDLAGDNHRSKGTEIALFGNDILTGNFRQKEYQGIGYAPFASNPNQAYASLVGQVLQARKRLVESGRRDWSLAIL
VPTKKMTRMVSDILREPFGNVPSISHSAAVDMEGPILAAEIIAFLLQKCGHDGSFDEFVELMCSYFHGRGGTAPTKGDMD
EAARFRKALSKWNECLAKGRTTPGNSVLQGTFAVHQATAALTFTGDPDADWVSVRDVLDTGACERLKDVAKDVRNVRLLE
RGTQLRQGLAQDWRDVGRYSNALAITRQSFVQEHFATAHKPESGVVVMNMHKAKGKQFDEVVIFEGWPKRFKGEIVANPD
RIVFGNVHDGVMTQARQNFRVSITRAKARTTIMTPRDDVCVLLRPVPA

Specific function: Essential helicase [H]

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005751
- InterPro:   IPR013986
- InterPro:   IPR014017
- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 67543; Mature: 67543

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDLTEAQKEILQAVGHQLVTGGPGSGKTTVSILKAAKIAREELKPGQRILFLSFARATV
CCCHHHHHHHHHHHHCHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
SRVLEAIDEESAITREERQRIEVDTYHSFFWRILKTHGYLVGFPRRMTILTPPNEAIALS
HHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCHHHHH
AVRSGYKAAKNLSDEEKAEKRAKEEAERVRLATEEGKVCFDLFADRVATLLHGSDKVRAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHH
VSTMYPYITLDEFQDTSADQWRVVQALGANSTLIALADPEQRIFDFIGADPERLNHFKAD
HHHHCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHH
FAPTVHDLAGDNHRSKGTEIALFGNDILTGNFRQKEYQGIGYAPFASNPNQAYASLVGQV
CCCHHHHHCCCCCCCCCCEEEEECCCEEECCCCHHHHCCCCCCCCCCCCHHHHHHHHHHH
LQARKRLVESGRRDWSLAILVPTKKMTRMVSDILREPFGNVPSISHSAAVDMEGPILAAE
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHHHHH
IIAFLLQKCGHDGSFDEFVELMCSYFHGRGGTAPTKGDMDEAARFRKALSKWNECLAKGR
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
TTPGNSVLQGTFAVHQATAALTFTGDPDADWVSVRDVLDTGACERLKDVAKDVRNVRLLE
CCCCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RGTQLRQGLAQDWRDVGRYSNALAITRQSFVQEHFATAHKPESGVVVMNMHKAKGKQFDE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCE
VVIFEGWPKRFKGEIVANPDRIVFGNVHDGVMTQARQNFRVSITRAKARTTIMTPRDDVC
EEEECCCCCCCCCCEEECCCEEEECCCCHHHHHHHCCCCEEEEEECCCCEEECCCCCCEE
VLLRPVPA
EEEECCCC
>Mature Secondary Structure
MVDLTEAQKEILQAVGHQLVTGGPGSGKTTVSILKAAKIAREELKPGQRILFLSFARATV
CCCHHHHHHHHHHHHCHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHH
SRVLEAIDEESAITREERQRIEVDTYHSFFWRILKTHGYLVGFPRRMTILTPPNEAIALS
HHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCHHHHH
AVRSGYKAAKNLSDEEKAEKRAKEEAERVRLATEEGKVCFDLFADRVATLLHGSDKVRAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHH
VSTMYPYITLDEFQDTSADQWRVVQALGANSTLIALADPEQRIFDFIGADPERLNHFKAD
HHHHCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHH
FAPTVHDLAGDNHRSKGTEIALFGNDILTGNFRQKEYQGIGYAPFASNPNQAYASLVGQV
CCCHHHHHCCCCCCCCCCEEEEECCCEEECCCCHHHHCCCCCCCCCCCCHHHHHHHHHHH
LQARKRLVESGRRDWSLAILVPTKKMTRMVSDILREPFGNVPSISHSAAVDMEGPILAAE
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHHHHH
IIAFLLQKCGHDGSFDEFVELMCSYFHGRGGTAPTKGDMDEAARFRKALSKWNECLAKGR
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
TTPGNSVLQGTFAVHQATAALTFTGDPDADWVSVRDVLDTGACERLKDVAKDVRNVRLLE
CCCCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RGTQLRQGLAQDWRDVGRYSNALAITRQSFVQEHFATAHKPESGVVVMNMHKAKGKQFDE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCE
VVIFEGWPKRFKGEIVANPDRIVFGNVHDGVMTQARQNFRVSITRAKARTTIMTPRDDVC
EEEECCCCCCCCCCEEECCCEEEECCCCHHHHHHHCCCCEEEEEECCCCEEECCCCCCEE
VLLRPVPA
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA