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The map label for this gene is yafC [C]

Identifier: 154246871

GI number: 154246871

Start: 3259819

End: 3260697

Strand: Direct

Name: yafC [C]

Synonym: Xaut_2936

Alternate gene names: 154246871

Gene position: 3259819-3260697 (Clockwise)

Preceding gene: 154246866

Following gene: 154246873

Centisome position: 61.4

GC content: 69.06

Gene sequence:

>879_bases
GTGGATCGACTTCAGGCCATGCAGGTGTTCGTGACCGTGGTGGAGGCGGGATCGTTCTCCGCTGCCGCACGGCAGATCGG
TGTCGGACAACCAGCCATCTCCAAGACCATCGCCCAGCTTGAGGAGCGCCTTCAGGTGCGCCTGCTCGTGCGCTCGACCC
ACAGCCTCGCGCCGACCGATGCGGGCGTGCGCTTCTATGAACGGGCGCGCGCGGCGATCCGAGAGGCGGATGAGGCCGAA
CTCGAAGCGCGGGGCGCCGGCGCGGGCCTGTCGGGACGTCTGCGCGTCTCGGCCGCCACGACCTTCGCGCGTCTGCTCAT
CGTTCCGCGCCTGCCGGAATTCCTAGCGCGCCATCCCGACATCGAAATCGACGTGCTGCTCGATGACCGGGTCATTGATC
TTGTCTCAGAGGGCATCGACATGGCTCTGCGGATGGGGGAATTGACCGATTCCGCCGCTATCGCCCGGCAGATCGCCCGC
AGCCGGCGTTCCGTGATCGCGACGCCCGCCTATCTCTCGCGCGCCGGCACGCCCCTGGTCCCGGCCGATCTCGCGACCCA
CGAGGCGATCGTCTACAGCCAGCTCGGCGCCAGCTGGACCTTCCGCCGGAACGGCACCGAGGCGTCCGTCGCGGTCCGCG
GACGCGTGCGTCTAAGCGCGGCGGAAGGCATCCGCGCGGCCGTGCTCGCCGACTTGGGGCTGACGGTCAATTCCGACTGG
ATGTTCGCCCCCGAGATCGAGAGCGGCGCGGTCCGGCGCGTGCTGGAGGACTGGGAGCTTCCGCCCGTCGATCTGTGGGC
GGTGTTCCCGACCGGGCGCCTCGCCAGCGCCAAGGCGCGCGCGTTTGCGGATTATGTGGAGAGCATCCTGGCCCAATAG

Upstream 100 bases:

>100_bases
GAACAGCGTCTGGGTCTGTTCGTGAGCCTGTTATGATCATTCCTGGAAAGTTGCGGCAGGCCGGTTGAAGCGATAACGTT
CATTCTCAGGAGGAATGAGT

Downstream 100 bases:

>100_bases
GGCTATTCGCGATGTACCGCGCAGCGCCATAATTTGTCGTTGGTCGGTGATCCGGAAGCGGACGTTTCCGCCACGGCGGG
CCGCTTCCTCGATGCCGCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDRLQAMQVFVTVVEAGSFSAAARQIGVGQPAISKTIAQLEERLQVRLLVRSTHSLAPTDAGVRFYERARAAIREADEAE
LEARGAGAGLSGRLRVSAATTFARLLIVPRLPEFLARHPDIEIDVLLDDRVIDLVSEGIDMALRMGELTDSAAIARQIAR
SRRSVIATPAYLSRAGTPLVPADLATHEAIVYSQLGASWTFRRNGTEASVAVRGRVRLSAAEGIRAAVLADLGLTVNSDW
MFAPEIESGAVRRVLEDWELPPVDLWAVFPTGRLASAKARAFADYVESILAQ

Sequences:

>Translated_292_residues
MDRLQAMQVFVTVVEAGSFSAAARQIGVGQPAISKTIAQLEERLQVRLLVRSTHSLAPTDAGVRFYERARAAIREADEAE
LEARGAGAGLSGRLRVSAATTFARLLIVPRLPEFLARHPDIEIDVLLDDRVIDLVSEGIDMALRMGELTDSAAIARQIAR
SRRSVIATPAYLSRAGTPLVPADLATHEAIVYSQLGASWTFRRNGTEASVAVRGRVRLSAAEGIRAAVLADLGLTVNSDW
MFAPEIESGAVRRVLEDWELPPVDLWAVFPTGRLASAKARAFADYVESILAQ
>Mature_292_residues
MDRLQAMQVFVTVVEAGSFSAAARQIGVGQPAISKTIAQLEERLQVRLLVRSTHSLAPTDAGVRFYERARAAIREADEAE
LEARGAGAGLSGRLRVSAATTFARLLIVPRLPEFLARHPDIEIDVLLDDRVIDLVSEGIDMALRMGELTDSAAIARQIAR
SRRSVIATPAYLSRAGTPLVPADLATHEAIVYSQLGASWTFRRNGTEASVAVRGRVRLSAAEGIRAAVLADLGLTVNSDW
MFAPEIESGAVRRVLEDWELPPVDLWAVFPTGRLASAKARAFADYVESILAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=31.9444444444444, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1787128, Length=283, Percent_Identity=31.4487632508834, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=29.96632996633, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1789639, Length=193, Percent_Identity=34.7150259067358, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1789440, Length=289, Percent_Identity=27.681660899654, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=28.0821917808219, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787589, Length=285, Percent_Identity=29.4736842105263, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788297, Length=141, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787601, Length=146, Percent_Identity=28.7671232876712, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI145693105, Length=152, Percent_Identity=26.9736842105263, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=136, Percent_Identity=36.7647058823529, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788706, Length=172, Percent_Identity=26.7441860465116, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789173, Length=249, Percent_Identity=26.5060240963855, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI157672245, Length=119, Percent_Identity=35.2941176470588, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31596; Mature: 31596

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLQAMQVFVTVVEAGSFSAAARQIGVGQPAISKTIAQLEERLQVRLLVRSTHSLAPTD
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AGVRFYERARAAIREADEAELEARGAGAGLSGRLRVSAATTFARLLIVPRLPEFLARHPD
HHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHCCCC
IEIDVLLDDRVIDLVSEGIDMALRMGELTDSAAIARQIARSRRSVIATPAYLSRAGTPLV
CEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCHHHHHCCCCCC
PADLATHEAIVYSQLGASWTFRRNGTEASVAVRGRVRLSAAEGIRAAVLADLGLTVNSDW
CCHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEEEEHHCCHHHHHHHHCCCEECCCE
MFAPEIESGAVRRVLEDWELPPVDLWAVFPTGRLASAKARAFADYVESILAQ
EECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDRLQAMQVFVTVVEAGSFSAAARQIGVGQPAISKTIAQLEERLQVRLLVRSTHSLAPTD
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AGVRFYERARAAIREADEAELEARGAGAGLSGRLRVSAATTFARLLIVPRLPEFLARHPD
HHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHCCCC
IEIDVLLDDRVIDLVSEGIDMALRMGELTDSAAIARQIARSRRSVIATPAYLSRAGTPLV
CEEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCHHHHHCCCCCC
PADLATHEAIVYSQLGASWTFRRNGTEASVAVRGRVRLSAAEGIRAAVLADLGLTVNSDW
CCHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEEEEHHCCHHHHHHHHCCCEECCCE
MFAPEIESGAVRRVLEDWELPPVDLWAVFPTGRLASAKARAFADYVESILAQ
EECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]