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The map label for this gene is yfcG [H]

Identifier: 154246870

GI number: 154246870

Start: 3259074

End: 3259706

Strand: Reverse

Name: yfcG [H]

Synonym: Xaut_2935

Alternate gene names: 154246870

Gene position: 3259706-3259074 (Counterclockwise)

Preceding gene: 154246872

Following gene: 154246869

Centisome position: 61.4

GC content: 66.19

Gene sequence:

>633_bases
ATGATCGAAGTCTACGCATTCGCCACGCCCAACAGCGTCAAGGTCCCCATCGCGCTGGAAGAGATGGACCTTGCCTATGA
GCTGAAGCCGGTCAACGTCCGAAAGGGCGAGCAGAAGAACGCCGCCTTCCTCGAACTGAACCCCAACGGCAAGGTGCCGG
TGATGGTCGAGCGCGACGGCGATGCCGCATTCGTGCTGGCCGAGAGCGCGGCGATCCTGGTTCATCTCGCGGAAAAGACC
GGCATGCTGCTGCCGGCTGAGGGAAGCGGACGGGCGCGCGTGTTCGAACACTTGTTCTTCCACGCGTCTGGCCTGAGCCC
GGCGTTCGGCAATGCCGGCTTCTTCAAGCGCTCGTCGCCCGAGCCCCAGCCCATCGCCGAGACCCGCTTCGCCGCCGAGG
CGGAACGCATCCTCGATCTTCTCGAAGCCAAGCTGGCGACCCAGCGCTTTACCGCTGGCGACGATTTCACCATCGCCGAC
ATCGCCCACTTCGGCTGGCTGTGGCGACGCGCATTTCCCGGCGTCACTCTGGACGCCCGCCCCAACCTCTCCCGCTGGTA
CGACCAGATCGCCACGCGGCCCGCCGTGCAACGCGCGATCACCCGTGTCGAGGCCCTCGTCCCGGCGGCGTGA

Upstream 100 bases:

>100_bases
TGAGAATGAACGTTATCGCTTCAACCGGCCTGCCGCAACTTTCCAGGAATGATCATAACAGGCTCACGAACAGACCCAGA
CGCTGTTCGCGGAGCTGAAC

Downstream 100 bases:

>100_bases
TCTTCCCCCCGATCCATTCGCCCCTGCGAACACACCAAGGAGCCATCCCATGTCCCGCTTCAGCGCTTACAAGGACGCCT
TCCCCAATGCCCAGCTCACC

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MIEVYAFATPNSVKVPIALEEMDLAYELKPVNVRKGEQKNAAFLELNPNGKVPVMVERDGDAAFVLAESAAILVHLAEKT
GMLLPAEGSGRARVFEHLFFHASGLSPAFGNAGFFKRSSPEPQPIAETRFAAEAERILDLLEAKLATQRFTAGDDFTIAD
IAHFGWLWRRAFPGVTLDARPNLSRWYDQIATRPAVQRAITRVEALVPAA

Sequences:

>Translated_210_residues
MIEVYAFATPNSVKVPIALEEMDLAYELKPVNVRKGEQKNAAFLELNPNGKVPVMVERDGDAAFVLAESAAILVHLAEKT
GMLLPAEGSGRARVFEHLFFHASGLSPAFGNAGFFKRSSPEPQPIAETRFAAEAERILDLLEAKLATQRFTAGDDFTIAD
IAHFGWLWRRAFPGVTLDARPNLSRWYDQIATRPAVQRAITRVEALVPAA
>Mature_210_residues
MIEVYAFATPNSVKVPIALEEMDLAYELKPVNVRKGEQKNAAFLELNPNGKVPVMVERDGDAAFVLAESAAILVHLAEKT
GMLLPAEGSGRARVFEHLFFHASGLSPAFGNAGFFKRSSPEPQPIAETRFAAEAERILDLLEAKLATQRFTAGDDFTIAD
IAHFGWLWRRAFPGVTLDARPNLSRWYDQIATRPAVQRAITRVEALVPAA

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4504187, Length=197, Percent_Identity=31.4720812182741, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI124249394, Length=197, Percent_Identity=31.4720812182741, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI167466164, Length=199, Percent_Identity=31.6582914572864, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1788640, Length=209, Percent_Identity=35.4066985645933, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082195, Length=212, Percent_Identity=34.4339622641509, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI87081789, Length=169, Percent_Identity=33.7278106508876, Blast_Score=80, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6324100, Length=232, Percent_Identity=26.2931034482759, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571670, Length=172, Percent_Identity=30.8139534883721, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19922160, Length=198, Percent_Identity=33.8383838383838, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17864598, Length=166, Percent_Identity=31.9277108433735, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17864592, Length=169, Percent_Identity=31.9526627218935, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI85725204, Length=167, Percent_Identity=29.3413173652695, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737923, Length=167, Percent_Identity=29.3413173652695, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 23075; Mature: 23075

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVYAFATPNSVKVPIALEEMDLAYELKPVNVRKGEQKNAAFLELNPNGKVPVMVERDG
CEEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEEEECCC
DAAFVLAESAAILVHLAEKTGMLLPAEGSGRARVFEHLFFHASGLSPAFGNAGFFKRSSP
CEEEEEECCCEEEEEEHHHCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EPQPIAETRFAAEAERILDLLEAKLATQRFTAGDDFTIADIAHFGWLWRRAFPGVTLDAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCEEECC
PNLSRWYDQIATRPAVQRAITRVEALVPAA
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIEVYAFATPNSVKVPIALEEMDLAYELKPVNVRKGEQKNAAFLELNPNGKVPVMVERDG
CEEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEEEECCC
DAAFVLAESAAILVHLAEKTGMLLPAEGSGRARVFEHLFFHASGLSPAFGNAGFFKRSSP
CEEEEEECCCEEEEEEHHHCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EPQPIAETRFAAEAERILDLLEAKLATQRFTAGDDFTIADIAHFGWLWRRAFPGVTLDAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCEEECC
PNLSRWYDQIATRPAVQRAITRVEALVPAA
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]