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The map label for this gene is bioD

Identifier: 154246854

GI number: 154246854

Start: 3242397

End: 3243038

Strand: Direct

Name: bioD

Synonym: Xaut_2919

Alternate gene names: 154246854

Gene position: 3242397-3243038 (Clockwise)

Preceding gene: 154246853

Following gene: 154246855

Centisome position: 61.07

GC content: 70.87

Gene sequence:

>642_bases
ATGACGGGCTACATCGTCACCGGGACGGATACCGGCATCGGCAAGACCATGTTCGCCGCCGCCCTCGCCGGCGCGCTGGA
TGCCGCTTATTGGAAGCCGGTGCAGTCCGGCCTTGAGGGAGAGACGGATTCCCAGGTGGTGCAGCGGCTGTCGGGCCTTG
CGCCCGATCGCATCCTGCCGGAGGCCTACCGGCTCGCGATGCCGGCCTCCCCCCACCGGGCGGCGGAGGCCGAGGGCATC
GCCATCGATCCCGATGCGCTGGTGCTTCCTGCGACCACGCGGCCGCTGGTGGTCGAGGGGGCCGGCGGACCCTTGGTGCC
GCTCACCCGCCGCCGGCTTTTCGCCGATGTGTTCGCCGCGTGGGGATTGCCGGTGATCCTGTGCGCCCGCACCAGCCTCG
GCACCATCAACCACACCTTGCTCGCCATCGAGGCCCTGTCGCGGAGGGGCATCGCGCTCCACGGCGTCGCCTTCATCGGC
GATGCCAACGAGGACAGCGAGCAGATCATCGCGGACCTCGGCGGAACGCGCCGCCTCGGGCGCCTGCCGCACCTGCCCGA
GGTGACGCCCGTCGCGCTCAAGGCCGCCTTCGCGGCGGCCTTCACCCTTGATGATTTCCGCCGAGAGGACCTCCGGCCAT
GA

Upstream 100 bases:

>100_bases
TCACGCTCAACGTGTCCGAAACCGACCTGGATGGTCTGGTGGACGCGCTCGCGCAGGCCCTTGCGGCGGAGCCGGGTACG
AAGGCCGTGAGGTCCGCCCC

Downstream 100 bases:

>100_bases
CCGCAAGCCCTTCTCCCGTCTGGCATCCCTTCACCCAGCACGCGCTTGCGCCTGAGCCGCCGGTGGTGGTGCGGGGGAAT
GGCGCGTGGCTGGAGACCGC

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTGYIVTGTDTGIGKTMFAAALAGALDAAYWKPVQSGLEGETDSQVVQRLSGLAPDRILPEAYRLAMPASPHRAAEAEGI
AIDPDALVLPATTRPLVVEGAGGPLVPLTRRRLFADVFAAWGLPVILCARTSLGTINHTLLAIEALSRRGIALHGVAFIG
DANEDSEQIIADLGGTRRLGRLPHLPEVTPVALKAAFAAAFTLDDFRREDLRP

Sequences:

>Translated_213_residues
MTGYIVTGTDTGIGKTMFAAALAGALDAAYWKPVQSGLEGETDSQVVQRLSGLAPDRILPEAYRLAMPASPHRAAEAEGI
AIDPDALVLPATTRPLVVEGAGGPLVPLTRRRLFADVFAAWGLPVILCARTSLGTINHTLLAIEALSRRGIALHGVAFIG
DANEDSEQIIADLGGTRRLGRLPHLPEVTPVALKAAFAAAFTLDDFRREDLRP
>Mature_212_residues
TGYIVTGTDTGIGKTMFAAALAGALDAAYWKPVQSGLEGETDSQVVQRLSGLAPDRILPEAYRLAMPASPHRAAEAEGIA
IDPDALVLPATTRPLVVEGAGGPLVPLTRRRLFADVFAAWGLPVILCARTSLGTINHTLLAIEALSRRGIALHGVAFIGD
ANEDSEQIIADLGGTRRLGRLPHLPEVTPVALKAAFAAAFTLDDFRREDLRP

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=170, Percent_Identity=39.4117647058824, Blast_Score=88, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324385, Length=188, Percent_Identity=38.8297872340425, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 22495; Mature: 22364

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGYIVTGTDTGIGKTMFAAALAGALDAAYWKPVQSGLEGETDSQVVQRLSGLAPDRILP
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHCH
EAYRLAMPASPHRAAEAEGIAIDPDALVLPATTRPLVVEGAGGPLVPLTRRRLFADVFAA
HHHHHCCCCCCCCCCCCCCEEECCCCEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
WGLPVILCARTSLGTINHTLLAIEALSRRGIALHGVAFIGDANEDSEQIIADLGGTRRLG
HCCCEEEHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEEEECCCCCHHHHHHHCCCCHHHC
RLPHLPEVTPVALKAAFAAAFTLDDFRREDLRP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TGYIVTGTDTGIGKTMFAAALAGALDAAYWKPVQSGLEGETDSQVVQRLSGLAPDRILP
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHCH
EAYRLAMPASPHRAAEAEGIAIDPDALVLPATTRPLVVEGAGGPLVPLTRRRLFADVFAA
HHHHHCCCCCCCCCCCCCCEEECCCCEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
WGLPVILCARTSLGTINHTLLAIEALSRRGIALHGVAFIGDANEDSEQIIADLGGTRRLG
HCCCEEEHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEEEECCCCCHHHHHHHCCCCHHHC
RLPHLPEVTPVALKAAFAAAFTLDDFRREDLRP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA