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The map label for this gene is blh [H]

Identifier: 154246833

GI number: 154246833

Start: 3219058

End: 3219810

Strand: Direct

Name: blh [H]

Synonym: Xaut_2897

Alternate gene names: 154246833

Gene position: 3219058-3219810 (Clockwise)

Preceding gene: 154246832

Following gene: 154246834

Centisome position: 60.63

GC content: 58.96

Gene sequence:

>753_bases
ATGAACTTTCGCCAACTGTATGAGCCGGAATCTTCAACCTACACTTACCTGTTCGGCTGCCGCGACACAGGAGAAGCCGT
GCTTCTCGACCCGGTCCTGGAGACGTTGGACCGGGACCTCTCCGCTCTCCAGGATCTCGGTTTAAGGCTCGCATACACAC
TCGAGACGCACATCCATGCCGACCATGTCACATCCGCTTGCCGGTTGCGGAGCATCACTGGATGCAAGGTGGCTTATCCT
GAGCTGGACGGTCTTCCTTGTGCCGACGTGGGCGTGAGCGAGGTCAACCCGCTGTCCGTCGGTCACCTCACATTCAATCC
CCTCTATACTCCTGGCCACACCGACTCGCATCACAGCTACCTCATCGACGTTCCTGGCGTGACGAGGGTTTTCACAGGCG
ATGCCCTTCTGATCGACGGGTGCGGACGAACGGACTTTCAGGGCGGTGACGCGGCCGCGCTCTACCGCTCGATCCACGAG
AAGATCTTCACTTTGCCCGGAGAAACTCTCGTCTATCCCGCCCATGACTACCAGCACCGCCACGTTAGTACGGTGGAGCA
GGAGCGCGAGCGAAACCCGCGTCTTGGCGCCGGCAAAAGCTTGGACGAGTTCATCCAGATCATGAGCGATCTCAACCTGC
CATATCCGAAGCGGATCGATATCGCTCTGCCCGCCAATCGAATGTGCGGGGACTGCCCGGATGAGGCCGAGATCATGAGA
GCTGAACCGGAAGGACCATCGATACAAGGCTAG

Upstream 100 bases:

>100_bases
CTCGACGGAAGCCGTCCATAATTCGGCCCTGCACGAAGCAACGCATGAGGTTCGCCAAAAGCGCGCGCGTCATGGACTCC
AAGCCGCCGGGAGCCTGAAC

Downstream 100 bases:

>100_bases
CTCGCCCTGCTGCATCTTCCGCCGATCTGATCAAGGGGTTCCCTCATGCTTCTTTCACGTCGAACGGTTCTGGCGGGAGC
TGGCGTTCTTGGATTAGGCA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNFRQLYEPESSTYTYLFGCRDTGEAVLLDPVLETLDRDLSALQDLGLRLAYTLETHIHADHVTSACRLRSITGCKVAYP
ELDGLPCADVGVSEVNPLSVGHLTFNPLYTPGHTDSHHSYLIDVPGVTRVFTGDALLIDGCGRTDFQGGDAAALYRSIHE
KIFTLPGETLVYPAHDYQHRHVSTVEQERERNPRLGAGKSLDEFIQIMSDLNLPYPKRIDIALPANRMCGDCPDEAEIMR
AEPEGPSIQG

Sequences:

>Translated_250_residues
MNFRQLYEPESSTYTYLFGCRDTGEAVLLDPVLETLDRDLSALQDLGLRLAYTLETHIHADHVTSACRLRSITGCKVAYP
ELDGLPCADVGVSEVNPLSVGHLTFNPLYTPGHTDSHHSYLIDVPGVTRVFTGDALLIDGCGRTDFQGGDAAALYRSIHE
KIFTLPGETLVYPAHDYQHRHVSTVEQERERNPRLGAGKSLDEFIQIMSDLNLPYPKRIDIALPANRMCGDCPDEAEIMR
AEPEGPSIQG
>Mature_250_residues
MNFRQLYEPESSTYTYLFGCRDTGEAVLLDPVLETLDRDLSALQDLGLRLAYTLETHIHADHVTSACRLRSITGCKVAYP
ELDGLPCADVGVSEVNPLSVGHLTFNPLYTPGHTDSHHSYLIDVPGVTRVFTGDALLIDGCGRTDFQGGDAAALYRSIHE
KIFTLPGETLVYPAHDYQHRHVSTVEQERERNPRLGAGKSLDEFIQIMSDLNLPYPKRIDIALPANRMCGDCPDEAEIMR
AEPEGPSIQG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=229, Percent_Identity=50.6550218340611, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI94538320, Length=170, Percent_Identity=31.7647058823529, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI94538322, Length=170, Percent_Identity=31.7647058823529, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI116642887, Length=172, Percent_Identity=34.3023255813954, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI21703352, Length=172, Percent_Identity=34.3023255813954, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1787158, Length=215, Percent_Identity=32.093023255814, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538952, Length=228, Percent_Identity=45.6140350877193, Blast_Score=197, Evalue=4e-51,
Organism=Drosophila melanogaster, GI221330176, Length=235, Percent_Identity=48.936170212766, Blast_Score=222, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24667711, Length=174, Percent_Identity=31.6091954022989, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356335, Length=174, Percent_Identity=31.6091954022989, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24667703, Length=174, Percent_Identity=31.6091954022989, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 27654; Mature: 27654

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFRQLYEPESSTYTYLFGCRDTGEAVLLDPVLETLDRDLSALQDLGLRLAYTLETHIHA
CCCHHHCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCH
DHVTSACRLRSITGCKVAYPELDGLPCADVGVSEVNPLSVGHLTFNPLYTPGHTDSHHSY
HHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCEEECEEEECCCCCCCCCCCCCEE
LIDVPGVTRVFTGDALLIDGCGRTDFQGGDAAALYRSIHEKIFTLPGETLVYPAHDYQHR
EEECCCCEEEEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
HVSTVEQERERNPRLGAGKSLDEFIQIMSDLNLPYPKRIDIALPANRMCGDCPDEAEIMR
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHEE
AEPEGPSIQG
ECCCCCCCCC
>Mature Secondary Structure
MNFRQLYEPESSTYTYLFGCRDTGEAVLLDPVLETLDRDLSALQDLGLRLAYTLETHIHA
CCCHHHCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCH
DHVTSACRLRSITGCKVAYPELDGLPCADVGVSEVNPLSVGHLTFNPLYTPGHTDSHHSY
HHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCEEECEEEECCCCCCCCCCCCCEE
LIDVPGVTRVFTGDALLIDGCGRTDFQGGDAAALYRSIHEKIFTLPGETLVYPAHDYQHR
EEECCCCEEEEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
HVSTVEQERERNPRLGAGKSLDEFIQIMSDLNLPYPKRIDIALPANRMCGDCPDEAEIMR
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHEE
AEPEGPSIQG
ECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]