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The map label for this gene is msrB [H]

Identifier: 154246779

GI number: 154246779

Start: 3170169

End: 3170624

Strand: Reverse

Name: msrB [H]

Synonym: Xaut_2840

Alternate gene names: 154246779

Gene position: 3170624-3170169 (Counterclockwise)

Preceding gene: 154246782

Following gene: 154246778

Centisome position: 59.72

GC content: 67.76

Gene sequence:

>456_bases
ATGCCCAATCCTGCCCCGTCTCCCGCCGCCGAGGGCCACGGCGATGCCAAGGTGGTGAAAAGCGAGAGCGAATGGCGCTC
CTGCCTGACGCCAGAGCAGTTTCGAATCACCCGCGAGCACGGCACCGAGCGCGCTTTCACCGGGCCCTACTGGGACGAGA
AGCGGGCGGGCCTCTATTCCTGCGTCGCCTGCGGAACCCCTCTGTTCCGCTCCGAAGCCAAGTATGATTCGGGTACCGGC
TGGCCGAGCTTCTTCGCCCCGATCTCCCCCGATTCGGTGGTGACGCACGAGGATACCTCCCACGGCATGCGCCGCATCGA
GGTGCGCTGCGCCAGCTGCGAGAGCCATCTGGGCCACGTCTTCCCGGATGGACCGGCCCCCACCGGCCTGCGCTTCTGCC
TGAACGGCACCGCCCTCAAGCTTGCGCCCGACGACGGAGATACCCGTGGCGCCTGA

Upstream 100 bases:

>100_bases
ACGCAGCCCGGCTCCAAAAACACCGCGCCGCGCCTGCCGCCGCCTTGCCGTCGCCACCTCGAATGCCTACCTCTCGTGGA
AATCGAACCAGGGGTTTCCA

Downstream 100 bases:

>100_bases
GCCGCCGCGCGCGCCACGGCGACCGAGTGAGCGCACTGTCCACGGCGTGACCCTCTCCGACGACTATGCTTGGCTGCGCG
CCGAAAACTGGCGCGCCGTC

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MPNPAPSPAAEGHGDAKVVKSESEWRSCLTPEQFRITREHGTERAFTGPYWDEKRAGLYSCVACGTPLFRSEAKYDSGTG
WPSFFAPISPDSVVTHEDTSHGMRRIEVRCASCESHLGHVFPDGPAPTGLRFCLNGTALKLAPDDGDTRGA

Sequences:

>Translated_151_residues
MPNPAPSPAAEGHGDAKVVKSESEWRSCLTPEQFRITREHGTERAFTGPYWDEKRAGLYSCVACGTPLFRSEAKYDSGTG
WPSFFAPISPDSVVTHEDTSHGMRRIEVRCASCESHLGHVFPDGPAPTGLRFCLNGTALKLAPDDGDTRGA
>Mature_150_residues
PNPAPSPAAEGHGDAKVVKSESEWRSCLTPEQFRITREHGTERAFTGPYWDEKRAGLYSCVACGTPLFRSEAKYDSGTGW
PSFFAPISPDSVVTHEDTSHGMRRIEVRCASCESHLGHVFPDGPAPTGLRFCLNGTALKLAPDDGDTRGA

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=140, Percent_Identity=50, Blast_Score=154, Evalue=3e-38,
Organism=Homo sapiens, GI301336162, Length=140, Percent_Identity=50, Blast_Score=154, Evalue=3e-38,
Organism=Homo sapiens, GI73089054, Length=140, Percent_Identity=50, Blast_Score=154, Evalue=3e-38,
Organism=Homo sapiens, GI37620216, Length=131, Percent_Identity=51.9083969465649, Blast_Score=152, Evalue=1e-37,
Organism=Homo sapiens, GI117606353, Length=130, Percent_Identity=54.6153846153846, Blast_Score=142, Evalue=9e-35,
Organism=Escherichia coli, GI1788077, Length=128, Percent_Identity=51.5625, Blast_Score=148, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17553450, Length=126, Percent_Identity=45.2380952380952, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=126, Percent_Identity=45.2380952380952, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=130, Percent_Identity=37.6923076923077, Blast_Score=102, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45553335, Length=130, Percent_Identity=46.9230769230769, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356369, Length=130, Percent_Identity=46.9230769230769, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24645799, Length=130, Percent_Identity=46.9230769230769, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI221378664, Length=127, Percent_Identity=47.244094488189, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI221378662, Length=134, Percent_Identity=44.7761194029851, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24645801, Length=141, Percent_Identity=43.9716312056738, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24645804, Length=141, Percent_Identity=43.9716312056738, Blast_Score=123, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16365; Mature: 16234

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNPAPSPAAEGHGDAKVVKSESEWRSCLTPEQFRITREHGTERAFTGPYWDEKRAGLYS
CCCCCCCCCCCCCCCEEEEECCHHHHHCCCHHHEEEEHHCCCCCCCCCCCCCCCCCCHHH
CVACGTPLFRSEAKYDSGTGWPSFFAPISPDSVVTHEDTSHGMRRIEVRCASCESHLGHV
HHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEHHHCHHHHCCCC
FPDGPAPTGLRFCLNGTALKLAPDDGDTRGA
CCCCCCCCCEEEEECCCEEEECCCCCCCCCC
>Mature Secondary Structure 
PNPAPSPAAEGHGDAKVVKSESEWRSCLTPEQFRITREHGTERAFTGPYWDEKRAGLYS
CCCCCCCCCCCCCCEEEEECCHHHHHCCCHHHEEEEHHCCCCCCCCCCCCCCCCCCHHH
CVACGTPLFRSEAKYDSGTGWPSFFAPISPDSVVTHEDTSHGMRRIEVRCASCESHLGHV
HHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEHHHCHHHHCCCC
FPDGPAPTGLRFCLNGTALKLAPDDGDTRGA
CCCCCCCCCEEEEECCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]