Click here to switch to the map view.

The map label for this gene is dapD [H]

Identifier: 154246588

GI number: 154246588

Start: 2941487

End: 2942344

Strand: Direct

Name: dapD [H]

Synonym: Xaut_2647

Alternate gene names: 154246588

Gene position: 2941487-2942344 (Clockwise)

Preceding gene: 154246587

Following gene: 154246594

Centisome position: 55.41

GC content: 69.35

Gene sequence:

>858_bases
ATGGCCGACGCCGCCCGCCTTGCCGATCTGTCCCGCATCATCGACGACGCCTTCGAGAAGCGCGCCGAGATCGGCTTTTC
CACCACGGGCGAGGTGCGTCTCGCCGTTGACGAGGCGCTCACCCTCCTCGACAGCGGCGCCGCCCGCGTGGCCGAAAAGG
GCGCCGATGGCACCTGGACCGTGAACCAGTGGCTGAAGAAGGCGGTGCTGCTCTCCTTCCGCCTCAACGACATGGAGCCC
ATCGCCGGCGGCCCCGGCGGCGCCCACTGGTGGGACAAGGTGCCCTCCAAGTTCGCCACCTGGGGCGAGACGGATTTCCG
CTCCGCCGGCTTCCGCGCCGTGCCGGGTGCCATCGTGCGCCGCTCGGCCTTCATCGCGCCCAACGTGGTGCTGATGCCGT
CCTTCGTGAACCTCGGCGCCCATGTGGGCGAGGGCACCATGGTGGACACCTGGGCCACCGTGGGCTCCTGCGCCCAGATC
GGCAAGAACGTGCACCTGTCCGGCGGCGTGGGCATCGGCGGCGTGCTGGAGCCGCTGCAGGCCGGCCCGGTGATCATTGA
GGACGACTGCTTCATCGGCGCCCGCTCGGAAGTGGTGGAGGGCGTGGTGGTGCGCACCGGTTCGGTGCTCTCCATGGGCG
TCTTCATCAGCGCCTCCACCAAGATCGTGGACCGGGAGACCGGCGAGGTCTTCGTGGGCGAGGTGCCGGCCTATTCGGTG
GTGGTGCCCGGCTCGCTGCCCGGCAAGCCCCTGCCCAACGGCCAACCCGGCCCTTCGCTCTATTGCGCGGTGATCGTGAA
GCGGGTGGACGCGCAGACCCGCTCCAAGACTTCCATCAACGACCTGCTGCGCGATTGA

Upstream 100 bases:

>100_bases
CGTGAAGGAACGCGGCTGACCTTTCATCCCACCCTGAATTGACTCGCCCTGAATTGACTTGCCCGGCCGCGCGGGGGCGC
GGCCGATCTGGAGGACCCCC

Downstream 100 bases:

>100_bases
TGGGAAGGGGTTTCGGCCTCCGTGAGATGGGGGCGGGGTGGTCGCGGTGGGTGCGGCGGTCTGGCCTGTGGGCAGTGGTG
CGATAACGTCTTGCCAGACG

Product: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MADAARLADLSRIIDDAFEKRAEIGFSTTGEVRLAVDEALTLLDSGAARVAEKGADGTWTVNQWLKKAVLLSFRLNDMEP
IAGGPGGAHWWDKVPSKFATWGETDFRSAGFRAVPGAIVRRSAFIAPNVVLMPSFVNLGAHVGEGTMVDTWATVGSCAQI
GKNVHLSGGVGIGGVLEPLQAGPVIIEDDCFIGARSEVVEGVVVRTGSVLSMGVFISASTKIVDRETGEVFVGEVPAYSV
VVPGSLPGKPLPNGQPGPSLYCAVIVKRVDAQTRSKTSINDLLRD

Sequences:

>Translated_285_residues
MADAARLADLSRIIDDAFEKRAEIGFSTTGEVRLAVDEALTLLDSGAARVAEKGADGTWTVNQWLKKAVLLSFRLNDMEP
IAGGPGGAHWWDKVPSKFATWGETDFRSAGFRAVPGAIVRRSAFIAPNVVLMPSFVNLGAHVGEGTMVDTWATVGSCAQI
GKNVHLSGGVGIGGVLEPLQAGPVIIEDDCFIGARSEVVEGVVVRTGSVLSMGVFISASTKIVDRETGEVFVGEVPAYSV
VVPGSLPGKPLPNGQPGPSLYCAVIVKRVDAQTRSKTSINDLLRD
>Mature_284_residues
ADAARLADLSRIIDDAFEKRAEIGFSTTGEVRLAVDEALTLLDSGAARVAEKGADGTWTVNQWLKKAVLLSFRLNDMEPI
AGGPGGAHWWDKVPSKFATWGETDFRSAGFRAVPGAIVRRSAFIAPNVVLMPSFVNLGAHVGEGTMVDTWATVGSCAQIG
KNVHLSGGVGIGGVLEPLQAGPVIIEDDCFIGARSEVVEGVVVRTGSVLSMGVFISASTKIVDRETGEVFVGEVPAYSVV
VPGSLPGKPLPNGQPGPSLYCAVIVKRVDAQTRSKTSINDLLRD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786362, Length=279, Percent_Identity=65.5913978494624, Blast_Score=329, Evalue=1e-91,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.117 [H]

Molecular weight: Translated: 29973; Mature: 29841

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAARLADLSRIIDDAFEKRAEIGFSTTGEVRLAVDEALTLLDSGAARVAEKGADGTWT
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHCCHHHHHHCCCCCCEE
VNQWLKKAVLLSFRLNDMEPIAGGPGGAHWWDKVPSKFATWGETDFRSAGFRAVPGAIVR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCHHHHCCCCCCHHCCCCCCCCHHHHH
RSAFIAPNVVLMPSFVNLGAHVGEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQ
HHHHCCCCEEEECHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHHHHHC
AGPVIIEDDCFIGARSEVVEGVVVRTGSVLSMGVFISASTKIVDRETGEVFVGEVPAYSV
CCCEEEECCCCCCCHHHHHHHHHEECCCEEEEEEEEECCCEEEECCCCCEEEECCCEEEE
VVPGSLPGKPLPNGQPGPSLYCAVIVKRVDAQTRSKTSINDLLRD
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
ADAARLADLSRIIDDAFEKRAEIGFSTTGEVRLAVDEALTLLDSGAARVAEKGADGTWT
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHCCHHHHHHCCCCCCEE
VNQWLKKAVLLSFRLNDMEPIAGGPGGAHWWDKVPSKFATWGETDFRSAGFRAVPGAIVR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCHHHHCCCCCCHHCCCCCCCCHHHHH
RSAFIAPNVVLMPSFVNLGAHVGEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQ
HHHHCCCCEEEECHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHHHHHC
AGPVIIEDDCFIGARSEVVEGVVVRTGSVLSMGVFISASTKIVDRETGEVFVGEVPAYSV
CCCEEEECCCCCCCHHHHHHHHHEECCCEEEEEEEEECCCEEEECCCCCEEEECCCEEEE
VVPGSLPGKPLPNGQPGPSLYCAVIVKRVDAQTRSKTSINDLLRD
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]