| Definition | Xanthobacter autotrophicus Py2 chromosome, complete genome. |
|---|---|
| Accession | NC_009720 |
| Length | 5,308,934 |
Click here to switch to the map view.
The map label for this gene is xecD [H]
Identifier: 154246529
GI number: 154246529
Start: 2877960
End: 2878826
Strand: Direct
Name: xecD [H]
Synonym: Xaut_2588
Alternate gene names: 154246529
Gene position: 2877960-2878826 (Clockwise)
Preceding gene: 154246528
Following gene: 154246530
Centisome position: 54.21
GC content: 69.09
Gene sequence:
>867_bases ATGGCTGATCCCGTGCCTGCCCATCCCGCCCTTGCTTCCGGTGCCGTGGCGGTCGTGACCGGCGGCGCCTCCGGCATCGG CCTTGCCGCCGCCGCCCGCTTCGCCGCGCGGGGCCTGAAGGTCGCCATCGCCGACCTGCCGGGGGAGAAGCTGGAGGCCG CCGCCGCGCACCTTGCGGGCATCGCGCCCGGCGGGACGGCCGATGTGCTTGCCGTTGCCACCGACGTGAGCGAACTGTCC GATATCGAGCGGCTGGAAGCCGAGGTGGCGGAGCGCTTCGGCGGCACCGACGTGCTGCTGAACAATGCCGGCATCCAGCC CGGCAGCGCCCTGTTCGGCCCGCTGGAAAACTGGGAGAAGGTGATCGCGGTGAACCTGTGGGGCATCATCCTCGGCTCCC GCGTGTTCGGGCCGAAAATGATTGCCCGCGGCAGGCCGGGGCTTATCGTCAATACCGGGTCCAAGCAGGGCATCACCACC CCGCCGGGCGACCCCGCCTACAATGTATCCAAGGCCGGGGTGAAGGTGTTCACCGAGGCCCTCGCCCACGAATTGCGCAA CATTGAGGGCTGCGCGGTCACCGCCCACCTGTTCATTCCCGGCTTCGTCTTCACGCCGCTGGCGGCCGGCGGGCGCACGG AGAAGCCGGCCGGAGCCTGGACGGCGGAACAGACCGTGGATTTCATGCTGGAGCGCCTTGAGGCCGGCGATTTCTACATC CTGTGCCCGGACAATGATGTGACCCGCGCCCTCGACCAGAAGCGGATCGCCTGGGCGGCGGGGGACATCATCGCCAATCG GCCGCCATTGTCGCGCTGGCACAAGGACTACGCGGCCGCCTTCGCCGCCTTTGTGAAGGGCGACTGA
Upstream 100 bases:
>100_bases GCGCCGTCCTGGTCGCTGGCACTGGCCTGCGCCCTCATCGTCGGGGGAGCCTTCGTCGCCACCCGGCGTTGAGATGGCGT CCCCCTGAAGGAGAAAAGCC
Downstream 100 bases:
>100_bases CGCCGCGTTGCAGCAACGATCTTGCGCCGGTGGCCTTGCACTTGAAGAGGCGAGGCCGTAGCACTCCGCGCCGGAACCGC CGCCTTCAGGGTGGCGACAG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: R-HPCDH; Aliphatic epoxide carboxylation component III [H]
Number of amino acids: Translated: 288; Mature: 287
Protein sequence:
>288_residues MADPVPAHPALASGAVAVVTGGASGIGLAAAARFAARGLKVAIADLPGEKLEAAAAHLAGIAPGGTADVLAVATDVSELS DIERLEAEVAERFGGTDVLLNNAGIQPGSALFGPLENWEKVIAVNLWGIILGSRVFGPKMIARGRPGLIVNTGSKQGITT PPGDPAYNVSKAGVKVFTEALAHELRNIEGCAVTAHLFIPGFVFTPLAAGGRTEKPAGAWTAEQTVDFMLERLEAGDFYI LCPDNDVTRALDQKRIAWAAGDIIANRPPLSRWHKDYAAAFAAFVKGD
Sequences:
>Translated_288_residues MADPVPAHPALASGAVAVVTGGASGIGLAAAARFAARGLKVAIADLPGEKLEAAAAHLAGIAPGGTADVLAVATDVSELS DIERLEAEVAERFGGTDVLLNNAGIQPGSALFGPLENWEKVIAVNLWGIILGSRVFGPKMIARGRPGLIVNTGSKQGITT PPGDPAYNVSKAGVKVFTEALAHELRNIEGCAVTAHLFIPGFVFTPLAAGGRTEKPAGAWTAEQTVDFMLERLEAGDFYI LCPDNDVTRALDQKRIAWAAGDIIANRPPLSRWHKDYAAAFAAFVKGD >Mature_287_residues ADPVPAHPALASGAVAVVTGGASGIGLAAAARFAARGLKVAIADLPGEKLEAAAAHLAGIAPGGTADVLAVATDVSELSD IERLEAEVAERFGGTDVLLNNAGIQPGSALFGPLENWEKVIAVNLWGIILGSRVFGPKMIARGRPGLIVNTGSKQGITTP PGDPAYNVSKAGVKVFTEALAHELRNIEGCAVTAHLFIPGFVFTPLAAGGRTEKPAGAWTAEQTVDFMLERLEAGDFYIL CPDNDVTRALDQKRIAWAAGDIIANRPPLSRWHKDYAAAFAAFVKGD
Specific function: Catalyzes the oxidation of 2-(R)-hydroxyalkyl thioesters of CoM to 2-oxoalkyl thioesters of CoM. The enzyme highly specific for the R enantiomers [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI31542939, Length=213, Percent_Identity=32.8638497652582, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI4758504, Length=207, Percent_Identity=33.8164251207729, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI83715985, Length=184, Percent_Identity=34.7826086956522, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI32483357, Length=197, Percent_Identity=32.48730964467, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=33.5260115606936, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI20149619, Length=210, Percent_Identity=30.4761904761905, Blast_Score=75, Evalue=9e-14, Organism=Homo sapiens, GI40254992, Length=226, Percent_Identity=30.9734513274336, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI25282469, Length=226, Percent_Identity=27.4336283185841, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI15277342, Length=201, Percent_Identity=33.8308457711443, Blast_Score=73, Evalue=4e-13, Organism=Homo sapiens, GI142976729, Length=202, Percent_Identity=29.2079207920792, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=32.5966850828729, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI109715829, Length=232, Percent_Identity=29.3103448275862, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI5031737, Length=195, Percent_Identity=31.2820512820513, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI33667109, Length=213, Percent_Identity=30.0469483568075, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503817, Length=190, Percent_Identity=30.5263157894737, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI1787335, Length=206, Percent_Identity=29.6116504854369, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI87082100, Length=198, Percent_Identity=32.3232323232323, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1790717, Length=220, Percent_Identity=28.1818181818182, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787820, Length=191, Percent_Identity=30.8900523560209, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1788459, Length=196, Percent_Identity=28.0612244897959, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1789057, Length=187, Percent_Identity=28.8770053475936, Blast_Score=64, Evalue=2e-11, Organism=Escherichia coli, GI1789208, Length=222, Percent_Identity=27.9279279279279, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17555706, Length=200, Percent_Identity=35.5, Blast_Score=95, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17564282, Length=207, Percent_Identity=32.3671497584541, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI25147288, Length=202, Percent_Identity=35.1485148514851, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17567345, Length=211, Percent_Identity=30.3317535545024, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17562908, Length=231, Percent_Identity=29.8701298701299, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17561402, Length=183, Percent_Identity=30.0546448087432, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17538480, Length=181, Percent_Identity=31.4917127071823, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560332, Length=221, Percent_Identity=29.8642533936652, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193203117, Length=223, Percent_Identity=27.8026905829596, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71994604, Length=174, Percent_Identity=33.9080459770115, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17559104, Length=178, Percent_Identity=29.2134831460674, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17507613, Length=201, Percent_Identity=30.3482587064677, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI32563809, Length=201, Percent_Identity=30.3482587064677, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71994600, Length=219, Percent_Identity=28.310502283105, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538182, Length=206, Percent_Identity=32.5242718446602, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193203115, Length=221, Percent_Identity=27.6018099547511, Blast_Score=67, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17538486, Length=227, Percent_Identity=28.1938325991189, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17551412, Length=212, Percent_Identity=31.1320754716981, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI193204405, Length=206, Percent_Identity=30.0970873786408, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24644339, Length=200, Percent_Identity=34.5, Blast_Score=98, Evalue=6e-21, Organism=Drosophila melanogaster, GI21357041, Length=203, Percent_Identity=34.9753694581281, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI21355631, Length=176, Percent_Identity=32.3863636363636, Blast_Score=84, Evalue=9e-17, Organism=Drosophila melanogaster, GI28571526, Length=171, Percent_Identity=34.5029239766082, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI17737361, Length=213, Percent_Identity=31.924882629108, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI221331218, Length=226, Percent_Identity=32.7433628318584, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24665243, Length=226, Percent_Identity=32.3008849557522, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI221331216, Length=227, Percent_Identity=33.0396475770925, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24665247, Length=227, Percent_Identity=32.5991189427313, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI23397609, Length=196, Percent_Identity=33.6734693877551, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI116007232, Length=179, Percent_Identity=32.9608938547486, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24584752, Length=198, Percent_Identity=30.8080808080808, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24649181, Length=200, Percent_Identity=30, Blast_Score=73, Evalue=3e-13, Organism=Drosophila melanogaster, GI116007234, Length=179, Percent_Identity=32.9608938547486, Blast_Score=73, Evalue=3e-13, Organism=Drosophila melanogaster, GI21358495, Length=205, Percent_Identity=28.780487804878, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI24639444, Length=200, Percent_Identity=31, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24580925, Length=192, Percent_Identity=28.6458333333333, Blast_Score=65, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.268 [H]
Molecular weight: Translated: 29821; Mature: 29690
Theoretical pI: Translated: 5.36; Mature: 5.36
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.0 %Met (Translated Protein) 1.7 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 0.7 %Met (Mature Protein) 1.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADPVPAHPALASGAVAVVTGGASGIGLAAAARFAARGLKVAIADLPGEKLEAAAAHLAG CCCCCCCCCCHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHC IAPGGTADVLAVATDVSELSDIERLEAEVAERFGGTDVLLNNAGIQPGSALFGPLENWEK CCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCHHHHHH VIAVNLWGIILGSRVFGPKMIARGRPGLIVNTGSKQGITTPPGDPAYNVSKAGVKVFTEA EEHHHHHHHHHCCHHCCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH LAHELRNIEGCAVTAHLFIPGFVFTPLAAGGRTEKPAGAWTAEQTVDFMLERLEAGDFYI HHHHHHCCCCCEEEEEHHHCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEE LCPDNDVTRALDQKRIAWAAGDIIANRPPLSRWHKDYAAAFAAFVKGD ECCCCHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure ADPVPAHPALASGAVAVVTGGASGIGLAAAARFAARGLKVAIADLPGEKLEAAAAHLAG CCCCCCCCCHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHC IAPGGTADVLAVATDVSELSDIERLEAEVAERFGGTDVLLNNAGIQPGSALFGPLENWEK CCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCHHHHHH VIAVNLWGIILGSRVFGPKMIARGRPGLIVNTGSKQGITTPPGDPAYNVSKAGVKVFTEA EEHHHHHHHHHCCHHCCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH LAHELRNIEGCAVTAHLFIPGFVFTPLAAGGRTEKPAGAWTAEQTVDFMLERLEAGDFYI HHHHHHCCCCCEEEEEHHHCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEE LCPDNDVTRALDQKRIAWAAGDIIANRPPLSRWHKDYAAAFAAFVKGD ECCCCHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7704278; 9405410; 12524213 [H]