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The map label for this gene is nudG [H]

Identifier: 154246527

GI number: 154246527

Start: 2876650

End: 2877066

Strand: Direct

Name: nudG [H]

Synonym: Xaut_2586

Alternate gene names: 154246527

Gene position: 2876650-2877066 (Clockwise)

Preceding gene: 154246526

Following gene: 154246528

Centisome position: 54.19

GC content: 71.22

Gene sequence:

>417_bases
GTGACCCTCCCCCTCAAGATCACCCTCGTCGCCGCCTGCGCCCTCGTGGACGCAGACGGCCGCGTGCTTGTGGCCCAGCG
GCCGGAGGGCAAGGCTCTCGCGGGCCTGTGGGAATTCCCCGGCGGCAAGGTGGAGCCGGGGGAGCGGCCCGAGGCGACGC
TGATCCGCGAGCTGGACGAGGAACTGGGCATCGCGGTGAAGGAGGCGTGCCTGGCCCCGCTCACCTTCGCGAGCCACGCC
TACGAGACCTTCCATCTGCTGATGCCCCTGTGGATCTGCCGCCGTTGGGAAGGCAGCATCCAGCGCAAGGAGCATCAGGC
GCTGCAATGGCTGCGCCCGGCGCGCCTGCGCGACATCCCCATGCCGCCCGCCGACGAGCCGCTGATCCCCGCCCTCATCG
ATCTGCTGGGCCCCTGA

Upstream 100 bases:

>100_bases
ATCTGCCCATGCAGCCCCGGCTGAACGTACCCCTTGAGGCCGGCACCATTGACCTCCACGCCGAGGTGGACGTCACCTGG
AGCGCCACTGGGAGCGCAAA

Downstream 100 bases:

>100_bases
GCGGCGCGTCATGACCTCCGCTGCCGCCACCCGCATCGGCCTGCTCGCCATCCTGTTGTGGGCGACCCTTGCCGTTCTCA
CGGCGGCGACGGGGCAGGTG

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MTLPLKITLVAACALVDADGRVLVAQRPEGKALAGLWEFPGGKVEPGERPEATLIRELDEELGIAVKEACLAPLTFASHA
YETFHLLMPLWICRRWEGSIQRKEHQALQWLRPARLRDIPMPPADEPLIPALIDLLGP

Sequences:

>Translated_138_residues
MTLPLKITLVAACALVDADGRVLVAQRPEGKALAGLWEFPGGKVEPGERPEATLIRELDEELGIAVKEACLAPLTFASHA
YETFHLLMPLWICRRWEGSIQRKEHQALQWLRPARLRDIPMPPADEPLIPALIDLLGP
>Mature_137_residues
TLPLKITLVAACALVDADGRVLVAQRPEGKALAGLWEFPGGKVEPGERPEATLIRELDEELGIAVKEACLAPLTFASHAY
ETFHLLMPLWICRRWEGSIQRKEHQALQWLRPARLRDIPMPPADEPLIPALIDLLGP

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=133, Percent_Identity=43.609022556391, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786288, Length=130, Percent_Identity=33.8461538461538, Blast_Score=76, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 15317; Mature: 15186

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPLKITLVAACALVDADGRVLVAQRPEGKALAGLWEFPGGKVEPGERPEATLIRELDE
CCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEHHCCCCCCCCCCCCCCHHHHHHHHHH
ELGIAVKEACLAPLTFASHAYETFHLLMPLWICRRWEGSIQRKEHQALQWLRPARLRDIP
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCC
MPPADEPLIPALIDLLGP
CCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TLPLKITLVAACALVDADGRVLVAQRPEGKALAGLWEFPGGKVEPGERPEATLIRELDE
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEHHCCCCCCCCCCCCCCHHHHHHHHHH
ELGIAVKEACLAPLTFASHAYETFHLLMPLWICRRWEGSIQRKEHQALQWLRPARLRDIP
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCC
MPPADEPLIPALIDLLGP
CCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]