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The map label for this gene is queC [H]

Identifier: 154245818

GI number: 154245818

Start: 2112641

End: 2113390

Strand: Reverse

Name: queC [H]

Synonym: Xaut_1874

Alternate gene names: 154245818

Gene position: 2113390-2112641 (Counterclockwise)

Preceding gene: 154245819

Following gene: 154245817

Centisome position: 39.81

GC content: 69.2

Gene sequence:

>750_bases
ATGACTGAGGCACAGGCCCATGCGGAGGAGGGCGCGCTGGTGCTCTTCTCCGGCGGGCAGGATTCGGCCACCTGCCTTGC
CTATGCGCTGGAGCGCTTCGGGCGGGTGGAGACCCTCGGCTTCCATTACGGCCAGCGCCACGCGGTGGAGCTGGAGCGCC
GCCCGGTGCTGCGCGATGCCTTCGCCACCCTGAAGCCCGCGTGGGCCTCACGGCTCGGTGCCGACCACATGCTGGACATG
CCGGTCCTGGGCCAGATCTCCGAGACCGCCCTCACCCGCGACGTGGCAGTGGAAATGGCGGAAGGCGGCCTGCCCAACAC
CTTCGTGCCCGGCCGCAACCTGGTGTTCCTCACCTTCGCGGCGGCGCTGGCCTACCGGCGGGGCCTGCGGCACATCATCG
GCGGCATGTGCGAGACCGATTTTTCCGGCTATCCCGACTGCCGGGACGACACCGTCAAGGCCATGCAGGTGGCGCTGAAC
CTCGGCATGGAGAAGCGCTTCGTCCTCCACACCCCGCTCATGTGGATCGACAAGGCCGAGACCTGGGGCCTCGCGGAACG
GCTCGGGGGCACCGCCCTCGTGGACCTGATCGTGGAGGACGCCCACACCTGCTACCTGGGCGAGCGTGGCAAGCGCCATG
CCTGGGGCTACGGCTGCGGTGAATGCCCCGCCTGCAAGTTGCGCGCGGATGGCTTTGCACGCTACCGCGCCGGCCAAGGC
GTGGAAAGACGCGCGGCCGCCACCAAATAA

Upstream 100 bases:

>100_bases
AGATCGCCAAGGGCCTGCACGCCATCGCCATCGAGGCCAAGGCCCCGGGTGAATGAGCCAGGCGAATGCGTGCGGGCGCA
GCATCGGGGACCCTTCCTGA

Downstream 100 bases:

>100_bases
CCGCCACTTTGCGCTAGATTTGCAACAAGTCGCTCAACGATTCGAGATCAATCATGGCCGAACCCGTGCCTGCCGCGTCC
CCCGACGATTACGGCGCCCA

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTEAQAHAEEGALVLFSGGQDSATCLAYALERFGRVETLGFHYGQRHAVELERRPVLRDAFATLKPAWASRLGADHMLDM
PVLGQISETALTRDVAVEMAEGGLPNTFVPGRNLVFLTFAAALAYRRGLRHIIGGMCETDFSGYPDCRDDTVKAMQVALN
LGMEKRFVLHTPLMWIDKAETWGLAERLGGTALVDLIVEDAHTCYLGERGKRHAWGYGCGECPACKLRADGFARYRAGQG
VERRAAATK

Sequences:

>Translated_249_residues
MTEAQAHAEEGALVLFSGGQDSATCLAYALERFGRVETLGFHYGQRHAVELERRPVLRDAFATLKPAWASRLGADHMLDM
PVLGQISETALTRDVAVEMAEGGLPNTFVPGRNLVFLTFAAALAYRRGLRHIIGGMCETDFSGYPDCRDDTVKAMQVALN
LGMEKRFVLHTPLMWIDKAETWGLAERLGGTALVDLIVEDAHTCYLGERGKRHAWGYGCGECPACKLRADGFARYRAGQG
VERRAAATK
>Mature_248_residues
TEAQAHAEEGALVLFSGGQDSATCLAYALERFGRVETLGFHYGQRHAVELERRPVLRDAFATLKPAWASRLGADHMLDMP
VLGQISETALTRDVAVEMAEGGLPNTFVPGRNLVFLTFAAALAYRRGLRHIIGGMCETDFSGYPDCRDDTVKAMQVALNL
GMEKRFVLHTPLMWIDKAETWGLAERLGGTALVDLIVEDAHTCYLGERGKRHAWGYGCGECPACKLRADGFARYRAGQGV
ERRAAATK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=234, Percent_Identity=47.008547008547, Blast_Score=199, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 27305; Mature: 27173

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAQAHAEEGALVLFSGGQDSATCLAYALERFGRVETLGFHYGQRHAVELERRPVLRDA
CCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEHHCCCCCCEEHHHCCCHHHHH
FATLKPAWASRLGADHMLDMPVLGQISETALTRDVAVEMAEGGLPNTFVPGRNLVFLTFA
HHHHCHHHHHHCCCCHHCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
AALAYRRGLRHIIGGMCETDFSGYPDCRDDTVKAMQVALNLGMEKRFVLHTPLMWIDKAE
HHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEECCC
TWGLAERLGGTALVDLIVEDAHTCYLGERGKRHAWGYGCGECPACKLRADGFARYRAGQG
CCCHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEECCCHHHHHCCCC
VERRAAATK
HHHHHCCCC
>Mature Secondary Structure 
TEAQAHAEEGALVLFSGGQDSATCLAYALERFGRVETLGFHYGQRHAVELERRPVLRDA
CCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEHHCCCCCCEEHHHCCCHHHHH
FATLKPAWASRLGADHMLDMPVLGQISETALTRDVAVEMAEGGLPNTFVPGRNLVFLTFA
HHHHCHHHHHHCCCCHHCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
AALAYRRGLRHIIGGMCETDFSGYPDCRDDTVKAMQVALNLGMEKRFVLHTPLMWIDKAE
HHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEECCC
TWGLAERLGGTALVDLIVEDAHTCYLGERGKRHAWGYGCGECPACKLRADGFARYRAGQG
CCCHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEECCCHHHHHCCCC
VERRAAATK
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA