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The map label for this gene is coaE [H]

Identifier: 154245774

GI number: 154245774

Start: 2056734

End: 2057336

Strand: Direct

Name: coaE [H]

Synonym: Xaut_1830

Alternate gene names: 154245774

Gene position: 2056734-2057336 (Clockwise)

Preceding gene: 154245773

Following gene: 154245775

Centisome position: 38.74

GC content: 70.65

Gene sequence:

>603_bases
ATGTGGATCCTCGGCCTCACCGGTTCCATCGGCATGGGCAAGTCGGCCACGGCGGGCCTGTTCCGCGCCATGGGGGTGCC
GGTGCATGACGCAGATGCCTCCGTGCATGCACTCTATCGTGGACGGGCGGTGGCTCCGGTGGAGGCGGCCTTTCCCGGCG
TGACGCGGGACGGCGCCATCGACCGGGCCGCACTCGGCGCCCGCGTGCTGGCAGATCCCGAGGCCATGAAGCGGCTGGAA
GCCATCGTCCATCCCCTGGTCCGCGCCGAGGAGGAGGCTTTCCTCGCGAAGGCCCGGACCGCGGGGGCGCGGCTGGTGGT
GCTGGATATCCCGCTGCTGTTCGAAACCGGAGGTCGCGGGCGCGTGGATGCGGTGGCTGTGGTCAGCGCGTCGAAAGCTG
TGCAGCGCGCCCGCGTGCTGGCGCGGCCCGGCATGACGGACGAAAAATTCGAGACCATTGTGGCCAAGCAGATGCCGGAC
GCGGAAAAGCGTCGCCGCGCCCATTTCGTCATCGACACCGGCCGGGGCTTTCCGGCGGCAGCCCATCAGGTGGCCGGCAT
CGTTCGGGCGCTGTCGGGTCCGGGGCGCCGGGCAGCCTGCTGA

Upstream 100 bases:

>100_bases
CTTCGAGCGCTGGTTCGGGGTGCGGCCGGAGGTGACCCCCGAATTGCGCGAGCTGTTGATCGCGGATCTTCGGGCCAAGG
GCCAGCTGGCGGCCTGACCC

Downstream 100 bases:

>100_bases
GGGAGAAGACCCATGCGCGAGATCGTGCTCGACACCGAGACCACCGGCCTTGAAGCCTATGGCGGCGACCGCCTCGTGGA
GATCGGCTGCGTGGAGATGG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MWILGLTGSIGMGKSATAGLFRAMGVPVHDADASVHALYRGRAVAPVEAAFPGVTRDGAIDRAALGARVLADPEAMKRLE
AIVHPLVRAEEEAFLAKARTAGARLVVLDIPLLFETGGRGRVDAVAVVSASKAVQRARVLARPGMTDEKFETIVAKQMPD
AEKRRRAHFVIDTGRGFPAAAHQVAGIVRALSGPGRRAAC

Sequences:

>Translated_200_residues
MWILGLTGSIGMGKSATAGLFRAMGVPVHDADASVHALYRGRAVAPVEAAFPGVTRDGAIDRAALGARVLADPEAMKRLE
AIVHPLVRAEEEAFLAKARTAGARLVVLDIPLLFETGGRGRVDAVAVVSASKAVQRARVLARPGMTDEKFETIVAKQMPD
AEKRRRAHFVIDTGRGFPAAAHQVAGIVRALSGPGRRAAC
>Mature_200_residues
MWILGLTGSIGMGKSATAGLFRAMGVPVHDADASVHALYRGRAVAPVEAAFPGVTRDGAIDRAALGARVLADPEAMKRLE
AIVHPLVRAEEEAFLAKARTAGARLVVLDIPLLFETGGRGRVDAVAVVSASKAVQRARVLARPGMTDEKFETIVAKQMPD
AEKRRRAHFVIDTGRGFPAAAHQVAGIVRALSGPGRRAAC

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=190, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI191252795, Length=190, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI110227607, Length=179, Percent_Identity=30.7262569832402, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227605, Length=179, Percent_Identity=30.7262569832402, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI110227603, Length=179, Percent_Identity=30.7262569832402, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI110227601, Length=179, Percent_Identity=30.7262569832402, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI205277394, Length=179, Percent_Identity=30.7262569832402, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1786292, Length=193, Percent_Identity=32.1243523316062, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17554944, Length=207, Percent_Identity=27.0531400966184, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320402, Length=210, Percent_Identity=26.1904761904762, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644728, Length=183, Percent_Identity=31.6939890710383, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24658602, Length=180, Percent_Identity=30.5555555555556, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21034; Mature: 21034

Theoretical pI: Translated: 11.20; Mature: 11.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWILGLTGSIGMGKSATAGLFRAMGVPVHDADASVHALYRGRAVAPVEAAFPGVTRDGAI
CEEEEECCCCCCCCCHHHHHHHHHCCCEECCCCHHHHHHCCCCCCCHHHHCCCCCCCCCC
DRAALGARVLADPEAMKRLEAIVHPLVRAEEEAFLAKARTAGARLVVLDIPLLFETGGRG
CHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCC
RVDAVAVVSASKAVQRARVLARPGMTDEKFETIVAKQMPDAEKRRRAHFVIDTGRGFPAA
CCHHEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHCCEEEEEECCCCCCHH
AHQVAGIVRALSGPGRRAAC
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MWILGLTGSIGMGKSATAGLFRAMGVPVHDADASVHALYRGRAVAPVEAAFPGVTRDGAI
CEEEEECCCCCCCCCHHHHHHHHHCCCEECCCCHHHHHHCCCCCCCHHHHCCCCCCCCCC
DRAALGARVLADPEAMKRLEAIVHPLVRAEEEAFLAKARTAGARLVVLDIPLLFETGGRG
CHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCC
RVDAVAVVSASKAVQRARVLARPGMTDEKFETIVAKQMPDAEKRRRAHFVIDTGRGFPAA
CCHHEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHCCEEEEEECCCCCCHH
AHQVAGIVRALSGPGRRAAC
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]