Click here to switch to the map view.

The map label for this gene is aroE [H]

Identifier: 154245773

GI number: 154245773

Start: 2055882

End: 2056730

Strand: Direct

Name: aroE [H]

Synonym: Xaut_1829

Alternate gene names: 154245773

Gene position: 2055882-2056730 (Clockwise)

Preceding gene: 154245772

Following gene: 154245774

Centisome position: 38.72

GC content: 68.32

Gene sequence:

>849_bases
GTGACGGTGCGGGTGTGCATCACCGGCTCGCCGGTCAGCTATTCACGGTCGCCGCTGCTTCATGGCTATTGGCTGAAGGC
CTACGGTATCGACGGAGATTACGGCCGCGAGGAAGTGCCCCCCGCGCAGGCGGCGGACTTCTACCGCAGCCTCGCGGCGC
GCGGCTATGCCGGCTGCAATGTCACCGCCCCCAACAAGGAAATCGCCTTCTCGGTTCTGGACGAGGCGGATGAGAGCGCG
GCGGCGCTGGGCTCCGCCAACACCCTGTGGCTGGAGGACGGCCGGCTGTGCGGCGCCAGCACCGACGGTTACGGCTTCAT
CGCCAATCTGGATGCGACAGTGCCGGGCTGGGATGGGGCGCGCAAGCTGGCGCTGGTGCTGGGCGCGGGCGGTGCCTCGC
GGGCCATCGTGCATGCAATGGTTGAGCGCGGGTTCGAGCGGATCGTGCTGGCCAATCGAACGCTGGAGCGGGCCGAGGCC
ATTGCGGTGGCGTTCGGCAAAACGGTCGTTCCGCTGGCCTTCGACAAGGCGGGCGAGGTGATGGCGGATGCCGACATCCT
GGTGAATTGCACCTCGCTTGGCATGAAGGGCGCAGCCGCGCTCACCGTGGACCTGTCGCGCCTCCGACCCGAGGCGGTGG
TGAGCGATATCGTCTATGTGCCGCTCCTCACTCCCTTGTTGACCGAGGCGGCGGCGCGCGGACTGCGTACTGTGGACGGC
CTCGGCATGCTGCTGCATCAGGGGGTGCCCGGCTTCGAGCGCTGGTTCGGGGTGCGGCCGGAGGTGACCCCCGAATTGCG
CGAGCTGTTGATCGCGGATCTTCGGGCCAAGGGCCAGCTGGCGGCCTGA

Upstream 100 bases:

>100_bases
GGGTGCACCTGTTCACCCGGGTGGATGGGGACCATTTCACCATCCTTGGCCTGCCGCTGCTCCAGCTGCTGCCCTTCTTC
CGGGAACAGGGGTTGCTGCC

Downstream 100 bases:

>100_bases
CCCATGTGGATCCTCGGCCTCACCGGTTCCATCGGCATGGGCAAGTCGGCCACGGCGGGCCTGTTCCGCGCCATGGGGGT
GCCGGTGCATGACGCAGATG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTVRVCITGSPVSYSRSPLLHGYWLKAYGIDGDYGREEVPPAQAADFYRSLAARGYAGCNVTAPNKEIAFSVLDEADESA
AALGSANTLWLEDGRLCGASTDGYGFIANLDATVPGWDGARKLALVLGAGGASRAIVHAMVERGFERIVLANRTLERAEA
IAVAFGKTVVPLAFDKAGEVMADADILVNCTSLGMKGAAALTVDLSRLRPEAVVSDIVYVPLLTPLLTEAAARGLRTVDG
LGMLLHQGVPGFERWFGVRPEVTPELRELLIADLRAKGQLAA

Sequences:

>Translated_282_residues
MTVRVCITGSPVSYSRSPLLHGYWLKAYGIDGDYGREEVPPAQAADFYRSLAARGYAGCNVTAPNKEIAFSVLDEADESA
AALGSANTLWLEDGRLCGASTDGYGFIANLDATVPGWDGARKLALVLGAGGASRAIVHAMVERGFERIVLANRTLERAEA
IAVAFGKTVVPLAFDKAGEVMADADILVNCTSLGMKGAAALTVDLSRLRPEAVVSDIVYVPLLTPLLTEAAARGLRTVDG
LGMLLHQGVPGFERWFGVRPEVTPELRELLIADLRAKGQLAA
>Mature_281_residues
TVRVCITGSPVSYSRSPLLHGYWLKAYGIDGDYGREEVPPAQAADFYRSLAARGYAGCNVTAPNKEIAFSVLDEADESAA
ALGSANTLWLEDGRLCGASTDGYGFIANLDATVPGWDGARKLALVLGAGGASRAIVHAMVERGFERIVLANRTLERAEAI
AVAFGKTVVPLAFDKAGEVMADADILVNCTSLGMKGAAALTVDLSRLRPEAVVSDIVYVPLLTPLLTEAAARGLRTVDGL
GMLLHQGVPGFERWFGVRPEVTPELRELLIADLRAKGQLAA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=267, Percent_Identity=35.2059925093633, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787983, Length=260, Percent_Identity=36.5384615384615, Blast_Score=124, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6320332, Length=271, Percent_Identity=27.3062730627306, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29831; Mature: 29699

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRVCITGSPVSYSRSPLLHGYWLKAYGIDGDYGREEVPPAQAADFYRSLAARGYAGCN
CEEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
VTAPNKEIAFSVLDEADESAAALGSANTLWLEDGRLCGASTDGYGFIANLDATVPGWDGA
CCCCCHHHHHHHHHHCCHHHHHCCCCCEEEEECCEEECCCCCCCEEEEECCCCCCCCCCC
RKLALVLGAGGASRAIVHAMVERGFERIVLANRTLERAEAIAVAFGKTVVPLAFDKAGEV
EEEEEEEECCCHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHCCEEEEEEECCCCCE
MADADILVNCTSLGMKGAAALTVDLSRLRPEAVVSDIVYVPLLTPLLTEAAARGLRTVDG
EECCCEEEEEHHCCCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LGMLLHQGVPGFERWFGVRPEVTPELRELLIADLRAKGQLAA
HHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVRVCITGSPVSYSRSPLLHGYWLKAYGIDGDYGREEVPPAQAADFYRSLAARGYAGCN
EEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
VTAPNKEIAFSVLDEADESAAALGSANTLWLEDGRLCGASTDGYGFIANLDATVPGWDGA
CCCCCHHHHHHHHHHCCHHHHHCCCCCEEEEECCEEECCCCCCCEEEEECCCCCCCCCCC
RKLALVLGAGGASRAIVHAMVERGFERIVLANRTLERAEAIAVAFGKTVVPLAFDKAGEV
EEEEEEEECCCHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHCCEEEEEEECCCCCE
MADADILVNCTSLGMKGAAALTVDLSRLRPEAVVSDIVYVPLLTPLLTEAAARGLRTVDG
EECCCEEEEEHHCCCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LGMLLHQGVPGFERWFGVRPEVTPELRELLIADLRAKGQLAA
HHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA