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The map label for this gene is tlyC [H]

Identifier: 154245757

GI number: 154245757

Start: 2041039

End: 2042013

Strand: Direct

Name: tlyC [H]

Synonym: Xaut_1813

Alternate gene names: 154245757

Gene position: 2041039-2042013 (Clockwise)

Preceding gene: 154245756

Following gene: 154245758

Centisome position: 38.45

GC content: 67.59

Gene sequence:

>975_bases
ATGTCCAACATCGACCAGCCAACGACCGAGACCAGCGCGGAACCGCAAAGTTTTCTCGATCGATTGCGTGCCCTCCTCGG
CACGTTCCGCCCGCACGGCTCGCTCCGCACTGACCTCGTGGAGGTGCTGGACGCGGCGGAAGCACCCGAGGAGGAAGGGG
AATTCACCCCGTCCGAGCGCAAGATGCTGCGCAACATCCTCCACCTCAAGGAGGTGGGCATCGGCGACATCATGGTGCCC
CGCGCCGAGATCGTCGCCGTGCGCAAGGATGTTTCGCTGGGCGAGTTGCTGAAGCTGTTCGTCGGCGTCGGCCATTCGCG
CCTCGTGGTCTATGACGACACGCTGGACGACCCCGTGGGCATGGTCCACATTCGCGACCTCATCGCTTTCCTCGCCGGCG
ACCTGACCAGCCAGCCGGGCAACAAGCTCGACCTTGGCGCGGTCAATCTCGACGGTTCGCTGGAGGACGCCGGGCTCATC
CGCCGCATCCTCTATGTGCCGCCCTCCATGCCGGCGGTGGACCTGCTGGTCGCCATGCAGGCGGCGCGCACCCATCTCGC
CCTCGTCATCGACGAATATGGCGGCACCGACGGCCTCGTTTCCATCGAGGACGTGGTGGAGGAGATCGTCGGCGAGATCG
AGGACGAGCACGACGAGGCGGCCGAGACCCTACTCATCCGCCAGCCGGACGGCAGCTTCCTCGCCGATGCGCGCACGCCG
CTGGAAGCCGCCGTCGAGGTGCTCGGCCCCACATTTGCGTCCGAGGAGGCCATGGAAGAGGTGGACAGCCTGGGCGGCCT
CCTGGTCATGGTGGCCTCGCGGGTGCCCAAGCAGGGGGAGGTGATCGCCCTGCCCGGCGGCTTCGAGGCGGAGGTGCTGG
AGGCGGACCCGCGCCGGGTGAAGAAGCTGCGCGTCATTCCCCCGCGGGAAGACGCGCCGGTGCCCGCCACCGAATCCAGC
ACATCCGACCTGTAG

Upstream 100 bases:

>100_bases
AGGAAATGGAGGCGCTGGAACGGCGGATCCTTGCGGGGCTCGGGATCGACGATCCCTATGCCCTGCCCCAGGACTGACGT
TCCAAGGCGAAGATCAGGCC

Downstream 100 bases:

>100_bases
CGCCCCCGCGTGCTCCCACCCTCCTCCCCGACCGCGCGGCTGCGCGGGCGCCTGCTGGCGCTGCGCTTCCTCTCCGGCTG
GCGCCGGCGCGGCGTCGCCT

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSNIDQPTTETSAEPQSFLDRLRALLGTFRPHGSLRTDLVEVLDAAEAPEEEGEFTPSERKMLRNILHLKEVGIGDIMVP
RAEIVAVRKDVSLGELLKLFVGVGHSRLVVYDDTLDDPVGMVHIRDLIAFLAGDLTSQPGNKLDLGAVNLDGSLEDAGLI
RRILYVPPSMPAVDLLVAMQAARTHLALVIDEYGGTDGLVSIEDVVEEIVGEIEDEHDEAAETLLIRQPDGSFLADARTP
LEAAVEVLGPTFASEEAMEEVDSLGGLLVMVASRVPKQGEVIALPGGFEAEVLEADPRRVKKLRVIPPREDAPVPATESS
TSDL

Sequences:

>Translated_324_residues
MSNIDQPTTETSAEPQSFLDRLRALLGTFRPHGSLRTDLVEVLDAAEAPEEEGEFTPSERKMLRNILHLKEVGIGDIMVP
RAEIVAVRKDVSLGELLKLFVGVGHSRLVVYDDTLDDPVGMVHIRDLIAFLAGDLTSQPGNKLDLGAVNLDGSLEDAGLI
RRILYVPPSMPAVDLLVAMQAARTHLALVIDEYGGTDGLVSIEDVVEEIVGEIEDEHDEAAETLLIRQPDGSFLADARTP
LEAAVEVLGPTFASEEAMEEVDSLGGLLVMVASRVPKQGEVIALPGGFEAEVLEADPRRVKKLRVIPPREDAPVPATESS
TSDL
>Mature_323_residues
SNIDQPTTETSAEPQSFLDRLRALLGTFRPHGSLRTDLVEVLDAAEAPEEEGEFTPSERKMLRNILHLKEVGIGDIMVPR
AEIVAVRKDVSLGELLKLFVGVGHSRLVVYDDTLDDPVGMVHIRDLIAFLAGDLTSQPGNKLDLGAVNLDGSLEDAGLIR
RILYVPPSMPAVDLLVAMQAARTHLALVIDEYGGTDGLVSIEDVVEEIVGEIEDEHDEAAETLLIRQPDGSFLADARTPL
EAAVEVLGPTFASEEAMEEVDSLGGLLVMVASRVPKQGEVIALPGGFEAEVLEADPRRVKKLRVIPPREDAPVPATESST
SDL

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=217, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI87082033, Length=259, Percent_Identity=32.4324324324324, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786879, Length=256, Percent_Identity=31.25, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI145693175, Length=263, Percent_Identity=25.0950570342205, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788119, Length=258, Percent_Identity=26.3565891472868, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790664, Length=265, Percent_Identity=21.1320754716981, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 34946; Mature: 34815

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIDQPTTETSAEPQSFLDRLRALLGTFRPHGSLRTDLVEVLDAAEAPEEEGEFTPSER
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHCCCCCCHHH
KMLRNILHLKEVGIGDIMVPRAEIVAVRKDVSLGELLKLFVGVGHSRLVVYDDTLDDPVG
HHHHHHHHHHHCCCCCEECCHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHH
MVHIRDLIAFLAGDLTSQPGNKLDLGAVNLDGSLEDAGLIRRILYVPPSMPAVDLLVAMQ
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
AARTHLALVIDEYGGTDGLVSIEDVVEEIVGEIEDEHDEAAETLLIRQPDGSFLADARTP
HHHHHEEEEEECCCCCCCCEEHHHHHHHHHHHHCCHHHHHHHEEEEECCCCCEECCCCCH
LEAAVEVLGPTFASEEAMEEVDSLGGLLVMVASRVPKQGEVIALPGGFEAEVLEADPRRV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHCCCCHHHH
KKLRVIPPREDAPVPATESSTSDL
HHEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNIDQPTTETSAEPQSFLDRLRALLGTFRPHGSLRTDLVEVLDAAEAPEEEGEFTPSER
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHCCCCCCHHH
KMLRNILHLKEVGIGDIMVPRAEIVAVRKDVSLGELLKLFVGVGHSRLVVYDDTLDDPVG
HHHHHHHHHHHCCCCCEECCHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHH
MVHIRDLIAFLAGDLTSQPGNKLDLGAVNLDGSLEDAGLIRRILYVPPSMPAVDLLVAMQ
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
AARTHLALVIDEYGGTDGLVSIEDVVEEIVGEIEDEHDEAAETLLIRQPDGSFLADARTP
HHHHHEEEEEECCCCCCCCEEHHHHHHHHHHHHCCHHHHHHHEEEEECCCCCEECCCCCH
LEAAVEVLGPTFASEEAMEEVDSLGGLLVMVASRVPKQGEVIALPGGFEAEVLEADPRRV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHCCCCHHHH
KKLRVIPPREDAPVPATESSTSDL
HHEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA