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The map label for this gene is fwdA [H]

Identifier: 154245739

GI number: 154245739

Start: 2023574

End: 2025223

Strand: Reverse

Name: fwdA [H]

Synonym: Xaut_1795

Alternate gene names: 154245739

Gene position: 2025223-2023574 (Counterclockwise)

Preceding gene: 154245740

Following gene: 154245738

Centisome position: 38.15

GC content: 65.82

Gene sequence:

>1650_bases
ATGAGGACGCGCATCACCGGTGGGCGCGTGTTCGACCCCGCCAACAATGTCATCGACCAGGTTCGCGACATCCTCTTGGA
AGACGGCCGCATCATCGCCGACGCGCCGCCGGCCAATGGTGAGCAAGTCGTTGATGCGAAGGGCACAATCGTGCTTGCGG
GCGGCATCGACCTGCATAGCCATATCGCCGGCGGCAAGGTCAATCTGGGCCGCCTGCTGATGAACGAGGACCGGGCGCTC
TATCCCGAGCCGTTCGGCGATTTCTGCGGCTGCGGCGGCGGGCGGGCGGCGCCCACCACCCACGCAACTGGTTGCCGCTA
CTCGCAAATGGGCTACACCGCCGTGTTCGAGCCGGCGGTGGTGGGGGCCAATGCCCGCCACGCGCACCTGGAGATGGCGG
ACATCCCCAATATCGACACCGGCGGCTTCCTGGTGCTGGGGAATGACGATTTCCTGTTGCGCCTCATCGCTCAGGGCGAG
GGCCAGCAGGCCATCAACGACTATGTGGCCTGGATGCTCAAGGCCACCCAGTGCTGCGCCATCAAGATCGTGAACCCCGG
CGGTATCAACGCCTTCAAGTTCAACGGGCGTGCCCTCGATCTTGACGAGACCGGGCCGTTTTACGGCCTCACCCCGCGCC
GAGTTCTGAACACACTTCAGCGCGCCGTATCGGAATTGGGGGTGCCGCACCCCATCCACCTCCATGGCTGCAACCTCGGG
GTGCCTGGCAACGTCAAGACGACGCTTGCCACCATCGGCGCGACCGAGGGCTTCCCGCTCCACCTCACCCACATCCAGTT
CCACTCCTACGGCACCGAGGGCGACCGGCACTTCTCCTCCGGCTCGGCCGAGATCGCGGAGGCGGTGAACGCCAATCCGC
ACATTTCGGTGGACGTGGGCCAGATCATGTTCGGCCAGACGGTGACCGCCTCGGCCGACCTCATGTCCCAGTATCGCAAC
CACGGCATTGCCGATCCCAAGAAGTGGATCGGCATGGACATCGAGATGGATGCCGCCTGCGGGGTGGTGCCGTTCAATTA
TCGCGACACCTCCTTCGTGAACGCGCTGCAATGGGCCATCGGGCTGGAATTGTTCCTGCTCATCGAGGACCCGTGGCGGG
TGTATCTGACCACCGACCATCCCAATGGCGGTCCCTTCACCTCCTACCCGCACCTCATCCGCCTGCTGATGGACAAGCCG
TTCCGCGACGACCATCTCTCGCGCATCCACAAGGCGGCGCGCGCGCACACCAGGCTTGCCGAGATTTCCCGCGAATACAC
GCTGGAGGAGATCGCGGTGGTGACCCGCGCTGCCCCGGCCCGCACCCTGGGCCTGAAGGATCGTGGCCATCTCGGCCCCG
GCGCCCGCGCGGACGTCGTGCTCTATGAGGAGCAGGCCGACCGCGAGGCCATGTTCGCCGCCCCGCGCCTTGTCATGAAG
GACGGCGAGGTGGTGGTGGTGAACGGCGAGGTGGTGGCCCTCACGCAGGGGCGCACCTATGCGGTGCATCCGCCATCGGA
CCCGCTCATGGACAAGCGGCTGGAGCGCTGGTTCGACGAGGCGGTGGGCCTGAAGGCCAGCCACTACAAGATCGCCGACG
GCGAGATCCGCGACGGCCAGGGCCCCGAAATCGTGGAGCTGACGCCATGA

Upstream 100 bases:

>100_bases
ATTCGGTGGTTTGCCTTCCGCTTCAGGCCCTTAGGCCTGCCGAACTGCCCAGCGTCGCCGAAGCGGCGGCGGCCATTCTT
GTGTCGTTCGGGAGGGGTGC

Downstream 100 bases:

>100_bases
CTTCCCAAGCCCCCATGATCATCAACGGCGTCGAGATCCGCGACAGCTTCGCCGAGGCGTTCCCCATGGCGGGAACGCGC
CTCATCATAACCGCCGATAC

Product: amidohydrolase 3

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MRTRITGGRVFDPANNVIDQVRDILLEDGRIIADAPPANGEQVVDAKGTIVLAGGIDLHSHIAGGKVNLGRLLMNEDRAL
YPEPFGDFCGCGGGRAAPTTHATGCRYSQMGYTAVFEPAVVGANARHAHLEMADIPNIDTGGFLVLGNDDFLLRLIAQGE
GQQAINDYVAWMLKATQCCAIKIVNPGGINAFKFNGRALDLDETGPFYGLTPRRVLNTLQRAVSELGVPHPIHLHGCNLG
VPGNVKTTLATIGATEGFPLHLTHIQFHSYGTEGDRHFSSGSAEIAEAVNANPHISVDVGQIMFGQTVTASADLMSQYRN
HGIADPKKWIGMDIEMDAACGVVPFNYRDTSFVNALQWAIGLELFLLIEDPWRVYLTTDHPNGGPFTSYPHLIRLLMDKP
FRDDHLSRIHKAARAHTRLAEISREYTLEEIAVVTRAAPARTLGLKDRGHLGPGARADVVLYEEQADREAMFAAPRLVMK
DGEVVVVNGEVVALTQGRTYAVHPPSDPLMDKRLERWFDEAVGLKASHYKIADGEIRDGQGPEIVELTP

Sequences:

>Translated_549_residues
MRTRITGGRVFDPANNVIDQVRDILLEDGRIIADAPPANGEQVVDAKGTIVLAGGIDLHSHIAGGKVNLGRLLMNEDRAL
YPEPFGDFCGCGGGRAAPTTHATGCRYSQMGYTAVFEPAVVGANARHAHLEMADIPNIDTGGFLVLGNDDFLLRLIAQGE
GQQAINDYVAWMLKATQCCAIKIVNPGGINAFKFNGRALDLDETGPFYGLTPRRVLNTLQRAVSELGVPHPIHLHGCNLG
VPGNVKTTLATIGATEGFPLHLTHIQFHSYGTEGDRHFSSGSAEIAEAVNANPHISVDVGQIMFGQTVTASADLMSQYRN
HGIADPKKWIGMDIEMDAACGVVPFNYRDTSFVNALQWAIGLELFLLIEDPWRVYLTTDHPNGGPFTSYPHLIRLLMDKP
FRDDHLSRIHKAARAHTRLAEISREYTLEEIAVVTRAAPARTLGLKDRGHLGPGARADVVLYEEQADREAMFAAPRLVMK
DGEVVVVNGEVVALTQGRTYAVHPPSDPLMDKRLERWFDEAVGLKASHYKIADGEIRDGQGPEIVELTP
>Mature_549_residues
MRTRITGGRVFDPANNVIDQVRDILLEDGRIIADAPPANGEQVVDAKGTIVLAGGIDLHSHIAGGKVNLGRLLMNEDRAL
YPEPFGDFCGCGGGRAAPTTHATGCRYSQMGYTAVFEPAVVGANARHAHLEMADIPNIDTGGFLVLGNDDFLLRLIAQGE
GQQAINDYVAWMLKATQCCAIKIVNPGGINAFKFNGRALDLDETGPFYGLTPRRVLNTLQRAVSELGVPHPIHLHGCNLG
VPGNVKTTLATIGATEGFPLHLTHIQFHSYGTEGDRHFSSGSAEIAEAVNANPHISVDVGQIMFGQTVTASADLMSQYRN
HGIADPKKWIGMDIEMDAACGVVPFNYRDTSFVNALQWAIGLELFLLIEDPWRVYLTTDHPNGGPFTSYPHLIRLLMDKP
FRDDHLSRIHKAARAHTRLAEISREYTLEEIAVVTRAAPARTLGLKDRGHLGPGARADVVLYEEQADREAMFAAPRLVMK
DGEVVVVNGEVVALTQGRTYAVHPPSDPLMDKRLERWFDEAVGLKASHYKIADGEIRDGQGPEIVELTP

Specific function: Unknown

COG id: COG1229

COG function: function code C; Formylmethanofuran dehydrogenase subunit A

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR012027
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: 1.2.99.5

Molecular weight: Translated: 59733; Mature: 59733

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRITGGRVFDPANNVIDQVRDILLEDGRIIADAPPANGEQVVDAKGTIVLAGGIDLHS
CCCCCCCCEEECCHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEECCCCEEEECCCCHHH
HIAGGKVNLGRLLMNEDRALYPEPFGDFCGCGGGRAAPTTHATGCRYSQMGYTAVFEPAV
HCCCCCEEECCEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEECCCCCEEEECCEE
VGANARHAHLEMADIPNIDTGGFLVLGNDDFLLRLIAQGEGQQAINDYVAWMLKATQCCA
ECCCCCEEEEEECCCCCCCCCCEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCCEEE
IKIVNPGGINAFKFNGRALDLDETGPFYGLTPRRVLNTLQRAVSELGVPHPIHLHGCNLG
EEEECCCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCC
VPGNVKTTLATIGATEGFPLHLTHIQFHSYGTEGDRHFSSGSAEIAEAVNANPHISVDVG
CCCCCEEEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCEEEEECC
QIMFGQTVTASADLMSQYRNHGIADPKKWIGMDIEMDAACGVVPFNYRDTSFVNALQWAI
CEEECCEEEHHHHHHHHHHHCCCCCCHHHHCCCEEECCCCCEEECCCCCHHHHHHHHHHH
GLELFLLIEDPWRVYLTTDHPNGGPFTSYPHLIRLLMDKPFRDDHLSRIHKAARAHTRLA
CEEEEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
EISREYTLEEIAVVTRAAPARTLGLKDRGHLGPGARADVVLYEEQADREAMFAAPRLVMK
HHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEEEEECCCCCHHHHHCCEEEEE
DGEVVVVNGEVVALTQGRTYAVHPPSDPLMDKRLERWFDEAVGLKASHYKIADGEIRDGQ
CCCEEEECCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCC
GPEIVELTP
CCEEEEECC
>Mature Secondary Structure
MRTRITGGRVFDPANNVIDQVRDILLEDGRIIADAPPANGEQVVDAKGTIVLAGGIDLHS
CCCCCCCCEEECCHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEECCCCEEEECCCCHHH
HIAGGKVNLGRLLMNEDRALYPEPFGDFCGCGGGRAAPTTHATGCRYSQMGYTAVFEPAV
HCCCCCEEECCEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEECCCCCEEEECCEE
VGANARHAHLEMADIPNIDTGGFLVLGNDDFLLRLIAQGEGQQAINDYVAWMLKATQCCA
ECCCCCEEEEEECCCCCCCCCCEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCCEEE
IKIVNPGGINAFKFNGRALDLDETGPFYGLTPRRVLNTLQRAVSELGVPHPIHLHGCNLG
EEEECCCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCC
VPGNVKTTLATIGATEGFPLHLTHIQFHSYGTEGDRHFSSGSAEIAEAVNANPHISVDVG
CCCCCEEEEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCEEEEECC
QIMFGQTVTASADLMSQYRNHGIADPKKWIGMDIEMDAACGVVPFNYRDTSFVNALQWAI
CEEECCEEEHHHHHHHHHHHCCCCCCHHHHCCCEEECCCCCEEECCCCCHHHHHHHHHHH
GLELFLLIEDPWRVYLTTDHPNGGPFTSYPHLIRLLMDKPFRDDHLSRIHKAARAHTRLA
CEEEEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
EISREYTLEEIAVVTRAAPARTLGLKDRGHLGPGARADVVLYEEQADREAMFAAPRLVMK
HHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEEEEECCCCCHHHHHCCEEEEE
DGEVVVVNGEVVALTQGRTYAVHPPSDPLMDKRLERWFDEAVGLKASHYKIADGEIRDGQ
CCCEEEECCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCC
GPEIVELTP
CCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]