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The map label for this gene is mtdB [H]

Identifier: 154245731

GI number: 154245731

Start: 2016285

End: 2017178

Strand: Direct

Name: mtdB [H]

Synonym: Xaut_1787

Alternate gene names: 154245731

Gene position: 2016285-2017178 (Clockwise)

Preceding gene: 154245730

Following gene: 154245732

Centisome position: 37.98

GC content: 69.46

Gene sequence:

>894_bases
ATGGCGGAATCCGCCCCCATTCTCCACATCATCACGCCCCTGAACCACGTCAGCCCGTTCGACGTGAACATGGCGGTGGA
TGCCGGCTACACCACCATCGCCCCCTATTCCCGCGTCGCGCTGAGCGAGGTGCGGGACCTGACGCAGGACATGATGTTCT
CCCGCGCGCCCCAGTCGGCGCCGCGCACCGGCCTGTTCATCGGCGGCAAGGATGCCGCCCTTGCCCTCGACATGGCGGCG
GAGGCAAAGGCCTCCATCTTCCCGCCCTTCGAGATTTCCATCTTTCCCGATCCCGCCGGCTCCTTCACCACCGCCGCCGC
CATGATCGCCAAGGTGGAGCAGGCGCTGCTGAAGACCCGGCCCAAGGGCCTGGAGGGCGTCGCCGTGCAGGTCTATGGCG
CCACCGGCGTGGTGGGCTCCATCGCCGCCGTCATCGCCGCGCAGGCGGGGGCGCTCGTCACCCTCGTCAGCCATCGCGAG
GTCGCCGCGGTGGACGAGAAGGCGAAGGACCTCAAGGCCCGCTTCGGCGTGGAGCTGGCCACCACCGCCGCCGTCACCGA
CGCGGAAAAGGCGAAGCTGGTTCCCGAGGCGGAAGTGGTGCTCGCCGCCGGCAAGGCCGGCGTGGAAATCCTCACCGCCG
CGCACCTTCAGGCCGCCACCCGGCTGCTGGTGGCAGCGGACGTGAACGCCGTGCCGCCCGCCGGCATCGCCGGCATCGGC
GCCCATGACGCGGCGGCCGTGCTGCCCCACGGCATCGGCATCGGCGCGCTTGCCATCGGCAATCTCAAATACGCCGTGCA
GCACACCCTGCTGAAGCAGATGTGCGTCACCGACACGCCGCTGTTCTTCGATCTTCCCGCCATCTTCAAGCTCGCCCGCG
AGCTGGACGCGTAG

Upstream 100 bases:

>100_bases
TCATACCCATTCGACTGCGTGCGGGGAAACAACCGCCGAGTTCCGGAGCGATCCGGGGCGAAGCCACCCGCTAATGTTTC
CCTCGACACGGAGCTGCGCC

Downstream 100 bases:

>100_bases
GAAGCCGCCATGCAGATCAGCACGTCCTCCCCCGCCCGGCCCCGCGCCCGCCGCGCGGGGCTCGCCCGCGTTCGCCCGCT
CCGGGAGACCCGGCCATGAC

Product: methylene-tetrahydromethanopterin dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MAESAPILHIITPLNHVSPFDVNMAVDAGYTTIAPYSRVALSEVRDLTQDMMFSRAPQSAPRTGLFIGGKDAALALDMAA
EAKASIFPPFEISIFPDPAGSFTTAAAMIAKVEQALLKTRPKGLEGVAVQVYGATGVVGSIAAVIAAQAGALVTLVSHRE
VAAVDEKAKDLKARFGVELATTAAVTDAEKAKLVPEAEVVLAAGKAGVEILTAAHLQAATRLLVAADVNAVPPAGIAGIG
AHDAAAVLPHGIGIGALAIGNLKYAVQHTLLKQMCVTDTPLFFDLPAIFKLARELDA

Sequences:

>Translated_297_residues
MAESAPILHIITPLNHVSPFDVNMAVDAGYTTIAPYSRVALSEVRDLTQDMMFSRAPQSAPRTGLFIGGKDAALALDMAA
EAKASIFPPFEISIFPDPAGSFTTAAAMIAKVEQALLKTRPKGLEGVAVQVYGATGVVGSIAAVIAAQAGALVTLVSHRE
VAAVDEKAKDLKARFGVELATTAAVTDAEKAKLVPEAEVVLAAGKAGVEILTAAHLQAATRLLVAADVNAVPPAGIAGIG
AHDAAAVLPHGIGIGALAIGNLKYAVQHTLLKQMCVTDTPLFFDLPAIFKLARELDA
>Mature_296_residues
AESAPILHIITPLNHVSPFDVNMAVDAGYTTIAPYSRVALSEVRDLTQDMMFSRAPQSAPRTGLFIGGKDAALALDMAAE
AKASIFPPFEISIFPDPAGSFTTAAAMIAKVEQALLKTRPKGLEGVAVQVYGATGVVGSIAAVIAAQAGALVTLVSHREV
AAVDEKAKDLKARFGVELATTAAVTDAEKAKLVPEAEVVLAAGKAGVEILTAAHLQAATRLLVAADVNAVPPAGIAGIGA
HDAAAVLPHGIGIGALAIGNLKYAVQHTLLKQMCVTDTPLFFDLPAIFKLARELDA

Specific function: Catalyzes the dehydrogenation of methylene-H(4)MPT [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.extorquens mtdA [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015259
- InterPro:   IPR016040 [H]

Pfam domain/function: PF09176 Mpt_N [H]

EC number: NA

Molecular weight: Translated: 30544; Mature: 30413

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESAPILHIITPLNHVSPFDVNMAVDAGYTTIAPYSRVALSEVRDLTQDMMFSRAPQSA
CCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
PRTGLFIGGKDAALALDMAAEAKASIFPPFEISIFPDPAGSFTTAAAMIAKVEQALLKTR
CCCEEEECCCCCEEEEEHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
PKGLEGVAVQVYGATGVVGSIAAVIAAQAGALVTLVSHREVAAVDEKAKDLKARFGVELA
CCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCEEE
TTAAVTDAEKAKLVPEAEVVLAAGKAGVEILTAAHLQAATRLLVAADVNAVPPAGIAGIG
HHHHHCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCEECCC
AHDAAAVLPHGIGIGALAIGNLKYAVQHTLLKQMCVTDTPLFFDLPAIFKLARELDA
CCCHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHCC
>Mature Secondary Structure 
AESAPILHIITPLNHVSPFDVNMAVDAGYTTIAPYSRVALSEVRDLTQDMMFSRAPQSA
CCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
PRTGLFIGGKDAALALDMAAEAKASIFPPFEISIFPDPAGSFTTAAAMIAKVEQALLKTR
CCCEEEECCCCCEEEEEHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
PKGLEGVAVQVYGATGVVGSIAAVIAAQAGALVTLVSHREVAAVDEKAKDLKARFGVELA
CCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCEEE
TTAAVTDAEKAKLVPEAEVVLAAGKAGVEILTAAHLQAATRLLVAADVNAVPPAGIAGIG
HHHHHCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCEECCC
AHDAAAVLPHGIGIGALAIGNLKYAVQHTLLKQMCVTDTPLFFDLPAIFKLARELDA
CCCHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9651254; 10848995 [H]