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The map label for this gene is hflK [H]

Identifier: 154245608

GI number: 154245608

Start: 1883283

End: 1884440

Strand: Reverse

Name: hflK [H]

Synonym: Xaut_1664

Alternate gene names: 154245608

Gene position: 1884440-1883283 (Counterclockwise)

Preceding gene: 154245609

Following gene: 154245607

Centisome position: 35.5

GC content: 67.44

Gene sequence:

>1158_bases
ATGTCGTGGAAGAATCAGAGTGGCGGCCCATGGGGTAATGGGCCGCGGGGTCCCTGGGGTTCGGGACCCTCTTCATCAGG
ACCGACGCCGCCAGATCTCGAAGACTTGATCCGCCGTAGCCAGGACCGCCTGCGCACCATGATACCGGGCTCCTTCGGGG
CCAAGGGCATCATCCTTTTGGTCGCGCTCGTGGTCGCCGGCTGGTTCCTCTCCGGCTTCTATCGCGTGCAGCCCGACGAG
CAGGGCGCGGTGCTGCGCTTCGGCAAGTTCGTGGGCGTCACCCAGCCCGGCCTCAACTATCACTGGCCCTACCCGATCGA
GACGGTGCTGACCCCCCGGGTCACCTTCGTCAACCGCATCGACATCGGCATGCGCACCGGCGAGGACACCCGGCGCGGCA
CATCGGTGATGCGTGACGTTCCGGAAGAGAGCCTCATGCTGACCGGTGACGAGAACATCGTCGACGTGGATTTCGCCGTG
TTCTGGCGCATCTCGAACGCCGAGCAGTACCTGTTCAACGTCCAGAACCCCGAGGGCACCATCAAGGCCGTGGCCGAGAG
CGCCATGCGCGAGGTCATCGGCCGCACCAACATCCAGCCCATCCTCACTGGCGCCCGGCAGAACATCGAGACCGGCGTGC
AGGAGCTGATGCAGTCGGTGCTCAACAGCTACAAGGCCGGCGTGGAAATCACGCAGGTGCAGATGCAGAAGGTCGACCCG
CCGAGCCAGGTCATCGACGCCTTCCGCGACGTGCAGGCCGCCCGCGCCGACGCCGAGCGCTCCCAGAACGAGGCGCAGAC
CTACGCCAACCGTGTCCTCCCCGAGGCCCGCGGCGAGGCCTCCCGCATCGAGAACGCCGCCCAGGGCTATCGCGAGCGCA
CGGTGGTGGAAGCCCGCGGCCAGGCGGCGCGCTTCCTCAAGATCTATGACGAGTACCAGAAGGCCAAGGTGGTGACGCGC
GAGCGCATGTATCTCGAGACCATGGAGCGCGTGCTCGGCGGCGTGGACAAGGTGATCGTGGATTCCGCCGGGACCCGACA
GGGACCAGGGGGTGTATCCGCCGGCGGGCCGGGAGGCGTCGTGCCCGTGCTGCCGCTCAACGATCTCCTCCGCCGCCAGC
CGGCGCCTGTCGCCCAGCCCCAGGGAGCCACGCGATGA

Upstream 100 bases:

>100_bases
CGCCTGTCGGATCGGGGGCGTTGCGGCATGCCGCACGGACCCGGCGGAGGCTCGCAGCGACGCGTGTGCCGATGGCGGCA
CCGCTCACGGGAGACGACGG

Downstream 100 bases:

>100_bases
GAAACCCGATCCTCGGCGGGGTCGTCGCCATTCTCGGCGTCGTTGCCCTCGTCCTCATCTATTCCGCGGCCTTCATCGTC
CAGCAGACCCAGCAGGCGCT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSWKNQSGGPWGNGPRGPWGSGPSSSGPTPPDLEDLIRRSQDRLRTMIPGSFGAKGIILLVALVVAGWFLSGFYRVQPDE
QGAVLRFGKFVGVTQPGLNYHWPYPIETVLTPRVTFVNRIDIGMRTGEDTRRGTSVMRDVPEESLMLTGDENIVDVDFAV
FWRISNAEQYLFNVQNPEGTIKAVAESAMREVIGRTNIQPILTGARQNIETGVQELMQSVLNSYKAGVEITQVQMQKVDP
PSQVIDAFRDVQAARADAERSQNEAQTYANRVLPEARGEASRIENAAQGYRERTVVEARGQAARFLKIYDEYQKAKVVTR
ERMYLETMERVLGGVDKVIVDSAGTRQGPGGVSAGGPGGVVPVLPLNDLLRRQPAPVAQPQGATR

Sequences:

>Translated_385_residues
MSWKNQSGGPWGNGPRGPWGSGPSSSGPTPPDLEDLIRRSQDRLRTMIPGSFGAKGIILLVALVVAGWFLSGFYRVQPDE
QGAVLRFGKFVGVTQPGLNYHWPYPIETVLTPRVTFVNRIDIGMRTGEDTRRGTSVMRDVPEESLMLTGDENIVDVDFAV
FWRISNAEQYLFNVQNPEGTIKAVAESAMREVIGRTNIQPILTGARQNIETGVQELMQSVLNSYKAGVEITQVQMQKVDP
PSQVIDAFRDVQAARADAERSQNEAQTYANRVLPEARGEASRIENAAQGYRERTVVEARGQAARFLKIYDEYQKAKVVTR
ERMYLETMERVLGGVDKVIVDSAGTRQGPGGVSAGGPGGVVPVLPLNDLLRRQPAPVAQPQGATR
>Mature_384_residues
SWKNQSGGPWGNGPRGPWGSGPSSSGPTPPDLEDLIRRSQDRLRTMIPGSFGAKGIILLVALVVAGWFLSGFYRVQPDEQ
GAVLRFGKFVGVTQPGLNYHWPYPIETVLTPRVTFVNRIDIGMRTGEDTRRGTSVMRDVPEESLMLTGDENIVDVDFAVF
WRISNAEQYLFNVQNPEGTIKAVAESAMREVIGRTNIQPILTGARQNIETGVQELMQSVLNSYKAGVEITQVQMQKVDPP
SQVIDAFRDVQAARADAERSQNEAQTYANRVLPEARGEASRIENAAQGYRERTVVEARGQAARFLKIYDEYQKAKVVTRE
RMYLETMERVLGGVDKVIVDSAGTRQGPGGVSAGGPGGVVPVLPLNDLLRRQPAPVAQPQGATR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=404, Percent_Identity=32.6732673267327, Blast_Score=196, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 42249; Mature: 42118

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWKNQSGGPWGNGPRGPWGSGPSSSGPTPPDLEDLIRRSQDRLRTMIPGSFGAKGIILL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VALVVAGWFLSGFYRVQPDEQGAVLRFGKFVGVTQPGLNYHWPYPIETVLTPRVTFVNRI
HHHHHHHHHHHCCEEECCCCCCCCEEHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHE
DIGMRTGEDTRRGTSVMRDVPEESLMLTGDENIVDVDFAVFWRISNAEQYLFNVQNPEGT
CCCCCCCCHHHHHHHHHHHCCHHHEEEECCCCEEEEEEEEEEEECCCCEEEEECCCCCHH
IKAVAESAMREVIGRTNIQPILTGARQNIETGVQELMQSVLNSYKAGVEITQVQMQKVDP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCC
PSQVIDAFRDVQAARADAERSQNEAQTYANRVLPEARGEASRIENAAQGYRERTVVEARG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHCC
QAARFLKIYDEYQKAKVVTRERMYLETMERVLGGVDKVIVDSAGTRQGPGGVSAGGPGGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCE
VPVLPLNDLLRRQPAPVAQPQGATR
EECCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SWKNQSGGPWGNGPRGPWGSGPSSSGPTPPDLEDLIRRSQDRLRTMIPGSFGAKGIILL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VALVVAGWFLSGFYRVQPDEQGAVLRFGKFVGVTQPGLNYHWPYPIETVLTPRVTFVNRI
HHHHHHHHHHHCCEEECCCCCCCCEEHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHE
DIGMRTGEDTRRGTSVMRDVPEESLMLTGDENIVDVDFAVFWRISNAEQYLFNVQNPEGT
CCCCCCCCHHHHHHHHHHHCCHHHEEEECCCCEEEEEEEEEEEECCCCEEEEECCCCCHH
IKAVAESAMREVIGRTNIQPILTGARQNIETGVQELMQSVLNSYKAGVEITQVQMQKVDP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCC
PSQVIDAFRDVQAARADAERSQNEAQTYANRVLPEARGEASRIENAAQGYRERTVVEARG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHCC
QAARFLKIYDEYQKAKVVTRERMYLETMERVLGGVDKVIVDSAGTRQGPGGVSAGGPGGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCE
VPVLPLNDLLRRQPAPVAQPQGATR
EECCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]