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The map label for this gene is tcyB [H]

Identifier: 154245547

GI number: 154245547

Start: 1812634

End: 1813317

Strand: Reverse

Name: tcyB [H]

Synonym: Xaut_1601

Alternate gene names: 154245547

Gene position: 1813317-1812634 (Counterclockwise)

Preceding gene: 154245550

Following gene: 154245546

Centisome position: 34.16

GC content: 65.06

Gene sequence:

>684_bases
GTGGGCTATGAATTCGATTTTTCATTTCTGAACGAGTATTGGCCTGACCTCCTTAATGGCGTCTGGCTGACGCTGGGCAT
GACCGTGGCATCGGTGCTGCCCGGATTCATCCTCGGCACCCTGTGCGCCGTGGGGCGCCTCTACGGGCCGCCCTATGTGC
AGCGCGCCGTCGTCTTCTATGTGGAGGCGATCCGCAACACCCCGCTCATCATCCAGGTGTTCTGGCTGTTCTTCGGCCTC
GCGGTTCTCGGGGCCAAGATCGGGCCGTTCCCCGCCGCCGTGATCGCGCTGGTGGTGAATGTGGGGGCCTATACGGCCGA
GATCATGCGGGCGGGCTTCCGCTCCATTCCCAAGGGCCAGATCGAGGCGGCGCACTGCCTTGCCCTCACGCCGACCCAGG
CCCTGTGGTCGGTGCAGCTGCCGCAGGCGGTGGAGCGGGTCTATCCCGCCCTCGTCAGCCAGTTCGTGCTGATGATGCTG
GCCACCGCCATCATGTCGCAGATCTCGGCGGAGGAACTCACCGGCGTCGCCTACATGATCCAGTCCTTCACCTTCCGCGG
CTTCGAGGTCTACCTCGTCATCGCCGTCATCTACCTCGCCATGGCCTCGCTGCTGCGCCTCAGCCTGATGGGTGTGGCGC
ACGTGTCCTTCCCCCGCCTTCGCCGTCTCGGCACGCCGCTGTGA

Upstream 100 bases:

>100_bases
GACCCATCGTCTCATTCGTGTGCACTTCTGGCGCACGCCAAAGCATTCATGCCAGTCATGAACGCAGATATAGTGTCATC
GGCGAAACGGACCTGATGCC

Downstream 100 bases:

>100_bases
GGATGCCATGCTGGGCCTGACCATCGAGCAGATCGCCTACCTCTTCCGCGGCGCCGGCTGGACCATCGTGCTGTCCGTGC
TGGGCTTTGTCGGCGGCACG

Product: polar amino acid ABC transporter inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MGYEFDFSFLNEYWPDLLNGVWLTLGMTVASVLPGFILGTLCAVGRLYGPPYVQRAVVFYVEAIRNTPLIIQVFWLFFGL
AVLGAKIGPFPAAVIALVVNVGAYTAEIMRAGFRSIPKGQIEAAHCLALTPTQALWSVQLPQAVERVYPALVSQFVLMML
ATAIMSQISAEELTGVAYMIQSFTFRGFEVYLVIAVIYLAMASLLRLSLMGVAHVSFPRLRRLGTPL

Sequences:

>Translated_227_residues
MGYEFDFSFLNEYWPDLLNGVWLTLGMTVASVLPGFILGTLCAVGRLYGPPYVQRAVVFYVEAIRNTPLIIQVFWLFFGL
AVLGAKIGPFPAAVIALVVNVGAYTAEIMRAGFRSIPKGQIEAAHCLALTPTQALWSVQLPQAVERVYPALVSQFVLMML
ATAIMSQISAEELTGVAYMIQSFTFRGFEVYLVIAVIYLAMASLLRLSLMGVAHVSFPRLRRLGTPL
>Mature_226_residues
GYEFDFSFLNEYWPDLLNGVWLTLGMTVASVLPGFILGTLCAVGRLYGPPYVQRAVVFYVEAIRNTPLIIQVFWLFFGLA
VLGAKIGPFPAAVIALVVNVGAYTAEIMRAGFRSIPKGQIEAAHCLALTPTQALWSVQLPQAVERVYPALVSQFVLMMLA
TAIMSQISAEELTGVAYMIQSFTFRGFEVYLVIAVIYLAMASLLRLSLMGVAHVSFPRLRRLGTPL

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=191, Percent_Identity=37.17277486911, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788645, Length=213, Percent_Identity=29.5774647887324, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786873, Length=212, Percent_Identity=32.5471698113208, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787086, Length=221, Percent_Identity=26.2443438914027, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788646, Length=199, Percent_Identity=26.1306532663317, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787087, Length=219, Percent_Identity=25.5707762557078, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082239, Length=153, Percent_Identity=35.9477124183007, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786874, Length=202, Percent_Identity=25.2475247524752, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786397, Length=145, Percent_Identity=32.4137931034483, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24961; Mature: 24830

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYEFDFSFLNEYWPDLLNGVWLTLGMTVASVLPGFILGTLCAVGRLYGPPYVQRAVVFY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VEAIRNTPLIIQVFWLFFGLAVLGAKIGPFPAAVIALVVNVGAYTAEIMRAGFRSIPKGQ
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IEAAHCLALTPTQALWSVQLPQAVERVYPALVSQFVLMMLATAIMSQISAEELTGVAYMI
CCHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSFTFRGFEVYLVIAVIYLAMASLLRLSLMGVAHVSFPRLRRLGTPL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GYEFDFSFLNEYWPDLLNGVWLTLGMTVASVLPGFILGTLCAVGRLYGPPYVQRAVVFY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VEAIRNTPLIIQVFWLFFGLAVLGAKIGPFPAAVIALVVNVGAYTAEIMRAGFRSIPKGQ
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IEAAHCLALTPTQALWSVQLPQAVERVYPALVSQFVLMMLATAIMSQISAEELTGVAYMI
CCHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSFTFRGFEVYLVIAVIYLAMASLLRLSLMGVAHVSFPRLRRLGTPL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]