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The map label for this gene is emrK [H]

Identifier: 154245459

GI number: 154245459

Start: 1721367

End: 1722584

Strand: Direct

Name: emrK [H]

Synonym: Xaut_1512

Alternate gene names: 154245459

Gene position: 1721367-1722584 (Clockwise)

Preceding gene: 154245438

Following gene: 154245460

Centisome position: 32.42

GC content: 70.77

Gene sequence:

>1218_bases
GTGACACAGGCGAACAGGATCGAACCGGCCGCGAACGACGCGGCTCCAGACACGCCCGCATCCGCGTCGCCGGTTGCCGG
CGTGACCGTGCTGAAGCGGCCCGGAGCCGCGCCCGGCGGCGTCCCGCTGGCGGACGCGCCCGCATCAGCCCCGGCGGCGG
AGACAGCGCCTGCCAGGAAGCGCTCGGTGAAGCCGTTCGTCTTCGGCGGCCTGCTGGCGGCGCTGGTGGTGGGCGGCGGC
TGGTATGGCACCCACTGGTGGCAGGTGGGTCGCTTCGAGGTCTCCACCGACGACGCCTATGTGGCCGCCGACACCTCCAT
CCTCGCCGCCAAGGTGGGGGGCTATGTGAAGAGCGTGGACGTGGTCGCCAACCAGTGGGTCAAGGCCGGCGACGTGATCG
CGCGCATCGATGATGGCGACTACACCCTCGCCCTGCGAGCCGCGCAGGACAAGATCGCCACTCAGGAGGCCGCCCTGTCG
CGCTTCGACGAGCAGGAGAAGGCGGCGGAAGCCGCCGTCGCCCAGGCGCGGGCGCAGCTTGTGGCCAACCAGGCCGACCT
GCAGCGCACGCAGCTGGAATTCGACCGGCAGAACAAGCTCGCCAGCTCCCATTTCGCCAGCCAGTCGGTGCTCGACAATG
CCCGCGCCGACCGCGACAAGGCGCAGGCGAACGTTGCCGCGGGACAGGCCGCCGTCGCTTCCGCCGAGGCTGCAGTGGCG
GTCATCAAGGCCCAGCGCACTGAGGCCGCGCGCGTGCTCGACCAGTACCGCACCGCCCGCGACCAGGCCCAGCGCGACCT
CGATTTCACCGTGGTGCGCGCGCCCATCGACGGGGTGGTGGGCAACCGCGCGGTGCAGGTGGGCCAGCTGGTGCAGGCCG
GTACCCGCCTTGCAGCGGTGGTGCCGCTGGCCGGAGTCTATGTGGACGCCAATTTCAAGGAAACCCAGCTCGGCCGCCTG
CATCAGGGCCAGAAGGTGCGGGTGTCGGTGGACGCCTATCCCGACCGGGATTTCGTCGGCACGGTCATGAGCGTTTCCCC
GGCGTCCGGCTCGGTGTTCAGCCTGCTGCCGCCGGAGAATGCCACCGGCAATTTCACCAAGATCGTGCAGCGCGTTCCCG
TGCGCATCGGCTTCGACGCCGGCGCGCTGGAAGGGCGCAACCTGCGGCCCGGCATGTCGGTGACCGCCGTGGTCGATACC
CGCGCCGACGCCTCCTGA

Upstream 100 bases:

>100_bases
TGTCAAAATATTTGACTGAACGGTTCAGTTCAATATACTCCATCCAGACGCTGAACTGAACCGTTCAGTTGAAATTCTTC
GCGCCAGCCGGAGGGCGACC

Downstream 100 bases:

>100_bases
GCGCCGGCCGTTCGGGCCCAAGGACGAACACCATGTCCACCACCATCACCCAAGGCACGCCCATCGCCCCGCCCCGCGCA
CCCGCCGCCGCGCCGGGCGT

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTQANRIEPAANDAAPDTPASASPVAGVTVLKRPGAAPGGVPLADAPASAPAAETAPARKRSVKPFVFGGLLAALVVGGG
WYGTHWWQVGRFEVSTDDAYVAADTSILAAKVGGYVKSVDVVANQWVKAGDVIARIDDGDYTLALRAAQDKIATQEAALS
RFDEQEKAAEAAVAQARAQLVANQADLQRTQLEFDRQNKLASSHFASQSVLDNARADRDKAQANVAAGQAAVASAEAAVA
VIKAQRTEAARVLDQYRTARDQAQRDLDFTVVRAPIDGVVGNRAVQVGQLVQAGTRLAAVVPLAGVYVDANFKETQLGRL
HQGQKVRVSVDAYPDRDFVGTVMSVSPASGSVFSLLPPENATGNFTKIVQRVPVRIGFDAGALEGRNLRPGMSVTAVVDT
RADAS

Sequences:

>Translated_405_residues
MTQANRIEPAANDAAPDTPASASPVAGVTVLKRPGAAPGGVPLADAPASAPAAETAPARKRSVKPFVFGGLLAALVVGGG
WYGTHWWQVGRFEVSTDDAYVAADTSILAAKVGGYVKSVDVVANQWVKAGDVIARIDDGDYTLALRAAQDKIATQEAALS
RFDEQEKAAEAAVAQARAQLVANQADLQRTQLEFDRQNKLASSHFASQSVLDNARADRDKAQANVAAGQAAVASAEAAVA
VIKAQRTEAARVLDQYRTARDQAQRDLDFTVVRAPIDGVVGNRAVQVGQLVQAGTRLAAVVPLAGVYVDANFKETQLGRL
HQGQKVRVSVDAYPDRDFVGTVMSVSPASGSVFSLLPPENATGNFTKIVQRVPVRIGFDAGALEGRNLRPGMSVTAVVDT
RADAS
>Mature_404_residues
TQANRIEPAANDAAPDTPASASPVAGVTVLKRPGAAPGGVPLADAPASAPAAETAPARKRSVKPFVFGGLLAALVVGGGW
YGTHWWQVGRFEVSTDDAYVAADTSILAAKVGGYVKSVDVVANQWVKAGDVIARIDDGDYTLALRAAQDKIATQEAALSR
FDEQEKAAEAAVAQARAQLVANQADLQRTQLEFDRQNKLASSHFASQSVLDNARADRDKAQANVAAGQAAVASAEAAVAV
IKAQRTEAARVLDQYRTARDQAQRDLDFTVVRAPIDGVVGNRAVQVGQLVQAGTRLAAVVPLAGVYVDANFKETQLGRLH
QGQKVRVSVDAYPDRDFVGTVMSVSPASGSVFSLLPPENATGNFTKIVQRVPVRIGFDAGALEGRNLRPGMSVTAVVDTR
ADAS

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=353, Percent_Identity=33.1444759206799, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789041, Length=319, Percent_Identity=33.8557993730408, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1790519, Length=310, Percent_Identity=29.6774193548387, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87081951, Length=319, Percent_Identity=25.3918495297806, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787013, Length=271, Percent_Identity=28.4132841328413, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789900, Length=344, Percent_Identity=26.7441860465116, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42388; Mature: 42257

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQANRIEPAANDAAPDTPASASPVAGVTVLKRPGAAPGGVPLADAPASAPAAETAPARK
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHH
RSVKPFVFGGLLAALVVGGGWYGTHWWQVGRFEVSTDDAYVAADTSILAAKVGGYVKSVD
HCCCCHHHHHHHHHHHHCCCCCCCCEEEECEEEECCCCEEEEECCHHHHHHHCCHHHHHH
VVANQWVKAGDVIARIDDGDYTLALRAAQDKIATQEAALSRFDEQEKAAEAAVAQARAQL
HHHHHHHCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VANQADLQRTQLEFDRQNKLASSHFASQSVLDNARADRDKAQANVAAGQAAVASAEAAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHH
VIKAQRTEAARVLDQYRTARDQAQRDLDFTVVRAPIDGVVGNRAVQVGQLVQAGTRLAAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHCCHHHHHHHHHHHCCHHHHE
VPLAGVYVDANFKETQLGRLHQGQKVRVSVDAYPDRDFVGTVMSVSPASGSVFSLLPPEN
EEEEEEEEECCCCHHHHHHCCCCCEEEEEEECCCCCCHHHHEEEECCCCCCEEEEECCCC
ATGNFTKIVQRVPVRIGFDAGALEGRNLRPGMSVTAVVDTRADAS
CCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
TQANRIEPAANDAAPDTPASASPVAGVTVLKRPGAAPGGVPLADAPASAPAAETAPARK
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHH
RSVKPFVFGGLLAALVVGGGWYGTHWWQVGRFEVSTDDAYVAADTSILAAKVGGYVKSVD
HCCCCHHHHHHHHHHHHCCCCCCCCEEEECEEEECCCCEEEEECCHHHHHHHCCHHHHHH
VVANQWVKAGDVIARIDDGDYTLALRAAQDKIATQEAALSRFDEQEKAAEAAVAQARAQL
HHHHHHHCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VANQADLQRTQLEFDRQNKLASSHFASQSVLDNARADRDKAQANVAAGQAAVASAEAAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHH
VIKAQRTEAARVLDQYRTARDQAQRDLDFTVVRAPIDGVVGNRAVQVGQLVQAGTRLAAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHCCHHHHHHHHHHHCCHHHHE
VPLAGVYVDANFKETQLGRLHQGQKVRVSVDAYPDRDFVGTVMSVSPASGSVFSLLPPEN
EEEEEEEEECCCCHHHHHHCCCCCEEEEEEECCCCCCHHHHEEEECCCCCCEEEEECCCC
ATGNFTKIVQRVPVRIGFDAGALEGRNLRPGMSVTAVVDTRADAS
CCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]