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The map label for this gene is ubiA [H]

Identifier: 154245433

GI number: 154245433

Start: 1695228

End: 1696199

Strand: Reverse

Name: ubiA [H]

Synonym: Xaut_1486

Alternate gene names: 154245433

Gene position: 1696199-1695228 (Counterclockwise)

Preceding gene: 154245434

Following gene: 154245432

Centisome position: 31.95

GC content: 68.62

Gene sequence:

>972_bases
TTGCCTTCCAGTTCCAGCGAAGGGGCGATGACCCCTCCCGTCGCCGATGCCGTCAGCGGTAATTGGGTAGATCGTTTCGC
ACCCCTGCGCGTGCGTCCCTACCTGCGGCTTGCCCGTCTGGACCGGCCCATCGGCTCGTGGCTGCTGCTGCTGCCGTGCT
GGTGGTCTACCGCGCTCGCCGCCATCGCCGACGATGCCCCCTATCCGGATCCCCGGCTGCTGGTGCTGTTCGCCATCGGC
GCGGTGGCCATGCGCGGCGCCGGCTGCACATGGAACGACATCCTCGACCGCAAGATCGACCAGCAGGTGGCGCGCACCCG
CAACCGCCCCGTCGCCTCCGGCGCCGTGAGCGTGCCGGCGGCCTTCGCCTTCCTGGTGGCGCAGGCCCTGATCGGCCTCG
CGGTGCTGCTGTCCCTGCCCCATTTCGCCATCATCACCGGCCTCGCCTCCCTTGGCGTGGTGGCAATTTACCCCTTGATG
AAGCGCGTCACCTCGGTGCCGCAGCTCATCCTGGGCATCGCCTTCTCGTGGGGGGCGCTCATGGGCTGGGCCAGCGTGAT
GCGCACCATCACCGATCCGGCCCTGCTGCTGTTCGCCGGCTGCGTGCTGTGGGTGTTCGCCTACGACACTATCTATGCTC
ACCAGGACAAGGAGGACGACGCCATTGCGGGCGTGCGTTCCACCGCGCTGCTGTTCGGCCGCGGCACCGCGCTCGTGGTG
GCGCTCTGCTACACTTTGGTGGTGGTCCTGTTCGGCATCGCCCTGCTTTCGGTGCCGTCGGGCCCATTCGCGGTGATGGG
CCTGATCGGCTTTGCCCTGCATCTGGCGGGGCAGGTGCGCCGGCTCGACATCGACGACGGTGCCCGCTGCCTCGCCGTGT
TCAAGTCCAACCGTGACGCCGGCCTGATCCTGTTCGCGGGCCTTGCCCTCGACACGCTCGTGCCCAACACGCTCGCGCCG
CTCCTGCCTTAG

Upstream 100 bases:

>100_bases
AGCGCGCTCGGCATCACCACCGGCTACAGCCTCGGCTCGCAGAAGAGTGGCGGCGTGTTCGACACGCTGAACGGCAACGC
GCTGAAGTGAGGTTGCCGGA

Downstream 100 bases:

>100_bases
GGCGTTTCGAGCGAAGTAGGCACCGCTCCGCGTGAAGAAGGCGCGAACTCAACCAGACAGGGCGTTCACCCCGCGCCGGC
GCGGGCGGAAAGCGCTCTCG

Product: 4-hydroxybenzoate polyprenyl transferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MPSSSSEGAMTPPVADAVSGNWVDRFAPLRVRPYLRLARLDRPIGSWLLLLPCWWSTALAAIADDAPYPDPRLLVLFAIG
AVAMRGAGCTWNDILDRKIDQQVARTRNRPVASGAVSVPAAFAFLVAQALIGLAVLLSLPHFAIITGLASLGVVAIYPLM
KRVTSVPQLILGIAFSWGALMGWASVMRTITDPALLLFAGCVLWVFAYDTIYAHQDKEDDAIAGVRSTALLFGRGTALVV
ALCYTLVVVLFGIALLSVPSGPFAVMGLIGFALHLAGQVRRLDIDDGARCLAVFKSNRDAGLILFAGLALDTLVPNTLAP
LLP

Sequences:

>Translated_323_residues
MPSSSSEGAMTPPVADAVSGNWVDRFAPLRVRPYLRLARLDRPIGSWLLLLPCWWSTALAAIADDAPYPDPRLLVLFAIG
AVAMRGAGCTWNDILDRKIDQQVARTRNRPVASGAVSVPAAFAFLVAQALIGLAVLLSLPHFAIITGLASLGVVAIYPLM
KRVTSVPQLILGIAFSWGALMGWASVMRTITDPALLLFAGCVLWVFAYDTIYAHQDKEDDAIAGVRSTALLFGRGTALVV
ALCYTLVVVLFGIALLSVPSGPFAVMGLIGFALHLAGQVRRLDIDDGARCLAVFKSNRDAGLILFAGLALDTLVPNTLAP
LLP
>Mature_322_residues
PSSSSEGAMTPPVADAVSGNWVDRFAPLRVRPYLRLARLDRPIGSWLLLLPCWWSTALAAIADDAPYPDPRLLVLFAIGA
VAMRGAGCTWNDILDRKIDQQVARTRNRPVASGAVSVPAAFAFLVAQALIGLAVLLSLPHFAIITGLASLGVVAIYPLMK
RVTSVPQLILGIAFSWGALMGWASVMRTITDPALLLFAGCVLWVFAYDTIYAHQDKEDDAIAGVRSTALLFGRGTALVVA
LCYTLVVVLFGIALLSVPSGPFAVMGLIGFALHLAGQVRRLDIDDGARCLAVFKSNRDAGLILFAGLALDTLVPNTLAPL
LP

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=294, Percent_Identity=47.2789115646259, Blast_Score=239, Evalue=2e-63,
Organism=Escherichia coli, GI1790473, Length=284, Percent_Identity=36.6197183098592, Blast_Score=155, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17553718, Length=298, Percent_Identity=39.9328859060403, Blast_Score=200, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI32565247, Length=293, Percent_Identity=38.9078498293515, Blast_Score=183, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17553720, Length=349, Percent_Identity=33.810888252149, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI32565245, Length=146, Percent_Identity=42.4657534246575, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI32565243, Length=145, Percent_Identity=42.0689655172414, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324370, Length=299, Percent_Identity=41.8060200668896, Blast_Score=208, Evalue=7e-55,
Organism=Drosophila melanogaster, GI21355567, Length=292, Percent_Identity=47.6027397260274, Blast_Score=235, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34343; Mature: 34212

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEEEEHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure 
PSSSSEGAMTPPVADAVSGNWVDRFAPLRVRPYLRLARLDRPIGSWLLLLPCWWSTALA
CCCCCCCCCCCCHHHHHCCCCHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AIADDAPYPDPRLLVLFAIGAVAMRGAGCTWNDILDRKIDQQVARTRNRPVASGAVSVPA
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
AFAFLVAQALIGLAVLLSLPHFAIITGLASLGVVAIYPLMKRVTSVPQLILGIAFSWGAL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGWASVMRTITDPALLLFAGCVLWVFAYDTIYAHQDKEDDAIAGVRSTALLFGRGTALVV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHH
ALCYTLVVVLFGIALLSVPSGPFAVMGLIGFALHLAGQVRRLDIDDGARCLAVFKSNRDA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHEEHHHHCCCCC
GLILFAGLALDTLVPNTLAPLLP
CEEEEHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA