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The map label for this gene is cysQ [H]

Identifier: 154245432

GI number: 154245432

Start: 1694217

End: 1695053

Strand: Reverse

Name: cysQ [H]

Synonym: Xaut_1485

Alternate gene names: 154245432

Gene position: 1695053-1694217 (Counterclockwise)

Preceding gene: 154245433

Following gene: 154245431

Centisome position: 31.93

GC content: 74.43

Gene sequence:

>837_bases
ATGAGCGTCGAGCCCACGCGCGGCCCCGACGGGCCTGCCCCCGCCCCCCTGGCGCGCCAGCTCACCGAAACGGTGACGGC
GGCGGGCGGGATCGCGCTCGCCATGTTCCAGGCCGGCGTGAAATCCTGGACCAAGGACAACAACTCCCCCGTCACCGAGG
CGGACATGGCGGTGGATGCCTTCCTCCACCGCCACCTCACCGCGCTGGATGCCGGCATCGGCTGGCTTTCCGAGGAATCC
GCCGACGGCCCGGCCCGCCTCGGCACCCGCCGGCTGTGGGTGGTGGACCCCATCGACGGCACCCGCGGCTTCATGGCCGG
CGGCCATGACTGGGCGGTCTCGGTGGCGCTGGTGGAAGAGGGCCGGCCGGTCCTCGCCGCCCTGTTCGCGCCCGCCACCG
GGGAGCTGTTCACCGCCGAGGCCGGCCGTGGCGCCATGCTCAATGGCGCCCCCCTCAAGGTGGCGCCGCGCCACACCCTC
GACGGCGCCCGGGTGGCCGGCCCCCCTGCCGATCTGGACGCCCTCGCCCGCCGTGCGGCGGTGGAGCGCCTGCCGCGCGT
GCGCTCGCTGGCATTGCGCCTCGCCCGCGTCGCCACCGGCGAGATCGATGTCGCCTTCGCCGCCGGCAACAGCAATGACT
GGGATCTGGCCGCCGCCGACCTCATCGTGCACGAGGCCCACGGCCTCCTGACCACCCGCGACGGCACCCCGCTCACCTAC
AACGCGCCGGAGCCGCGCCACCCCGCGCTGCTCTGCGCCGGCCCCACGCTTCACGCCGCCCTGGTGGAGACCGCGCCGCA
GCCCCCGTTTTTCAACGCCACTTTAGATCAGCGCTAG

Upstream 100 bases:

>100_bases
GCCGGCGCGGGCGGAAAGCGCTCTCGGCGGGGCGCGCATTGACGCAGTGCAGCACAAGTCTCCTTGCCTCGGGGCGCCGA
CGCCCCTATGTGGCAGGCCC

Downstream 100 bases:

>100_bases
TTGGGACAAGCCATGACTGACACGCAGAAACAGTTGCCGCACCTCGTTTTCGGCGGCGAGCTCACCACCCTCGACGGCTC
CGAGTTCAAGGATCTGTCCA

Product: inositol monophosphatase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSVEPTRGPDGPAPAPLARQLTETVTAAGGIALAMFQAGVKSWTKDNNSPVTEADMAVDAFLHRHLTALDAGIGWLSEES
ADGPARLGTRRLWVVDPIDGTRGFMAGGHDWAVSVALVEEGRPVLAALFAPATGELFTAEAGRGAMLNGAPLKVAPRHTL
DGARVAGPPADLDALARRAAVERLPRVRSLALRLARVATGEIDVAFAAGNSNDWDLAAADLIVHEAHGLLTTRDGTPLTY
NAPEPRHPALLCAGPTLHAALVETAPQPPFFNATLDQR

Sequences:

>Translated_278_residues
MSVEPTRGPDGPAPAPLARQLTETVTAAGGIALAMFQAGVKSWTKDNNSPVTEADMAVDAFLHRHLTALDAGIGWLSEES
ADGPARLGTRRLWVVDPIDGTRGFMAGGHDWAVSVALVEEGRPVLAALFAPATGELFTAEAGRGAMLNGAPLKVAPRHTL
DGARVAGPPADLDALARRAAVERLPRVRSLALRLARVATGEIDVAFAAGNSNDWDLAAADLIVHEAHGLLTTRDGTPLTY
NAPEPRHPALLCAGPTLHAALVETAPQPPFFNATLDQR
>Mature_277_residues
SVEPTRGPDGPAPAPLARQLTETVTAAGGIALAMFQAGVKSWTKDNNSPVTEADMAVDAFLHRHLTALDAGIGWLSEESA
DGPARLGTRRLWVVDPIDGTRGFMAGGHDWAVSVALVEEGRPVLAALFAPATGELFTAEAGRGAMLNGAPLKVAPRHTLD
GARVAGPPADLDALARRAAVERLPRVRSLALRLARVATGEIDVAFAAGNSNDWDLAAADLIVHEAHGLLTTRDGTPLTYN
APEPRHPALLCAGPTLHAALVETAPQPPFFNATLDQR

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=240, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788882, Length=208, Percent_Identity=35.0961538461538, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790659, Length=214, Percent_Identity=28.0373831775701, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193202570, Length=252, Percent_Identity=29.3650793650794, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320493, Length=220, Percent_Identity=29.0909090909091, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24664918, Length=254, Percent_Identity=32.2834645669291, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357957, Length=246, Percent_Identity=28.0487804878049, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24664922, Length=163, Percent_Identity=31.9018404907975, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21357303, Length=222, Percent_Identity=28.8288288288288, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24664926, Length=167, Percent_Identity=31.7365269461078, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357329, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29075; Mature: 28944

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEPTRGPDGPAPAPLARQLTETVTAAGGIALAMFQAGVKSWTKDNNSPVTEADMAVDA
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
FLHRHLTALDAGIGWLSEESADGPARLGTRRLWVVDPIDGTRGFMAGGHDWAVSVALVEE
HHHHHHHHHHHCCCCCCCCCCCCCHHHCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECC
GRPVLAALFAPATGELFTAEAGRGAMLNGAPLKVAPRHTLDGARVAGPPADLDALARRAA
CCCEEEEEECCCCCCEEEECCCCCCEECCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHH
VERLPRVRSLALRLARVATGEIDVAFAAGNSNDWDLAAADLIVHEAHGLLTTRDGTPLTY
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCCEEE
NAPEPRHPALLCAGPTLHAALVETAPQPPFFNATLDQR
CCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVEPTRGPDGPAPAPLARQLTETVTAAGGIALAMFQAGVKSWTKDNNSPVTEADMAVDA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
FLHRHLTALDAGIGWLSEESADGPARLGTRRLWVVDPIDGTRGFMAGGHDWAVSVALVEE
HHHHHHHHHHHCCCCCCCCCCCCCHHHCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECC
GRPVLAALFAPATGELFTAEAGRGAMLNGAPLKVAPRHTLDGARVAGPPADLDALARRAA
CCCEEEEEECCCCCCEEEECCCCCCEECCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHH
VERLPRVRSLALRLARVATGEIDVAFAAGNSNDWDLAAADLIVHEAHGLLTTRDGTPLTY
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCCEEE
NAPEPRHPALLCAGPTLHAALVETAPQPPFFNATLDQR
CCCCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]