Click here to switch to the map view.

The map label for this gene is divJ [H]

Identifier: 154245353

GI number: 154245353

Start: 1610643

End: 1612097

Strand: Direct

Name: divJ [H]

Synonym: Xaut_1406

Alternate gene names: 154245353

Gene position: 1610643-1612097 (Clockwise)

Preceding gene: 154245350

Following gene: 154245354

Centisome position: 30.34

GC content: 72.58

Gene sequence:

>1455_bases
GTGCGTCACCTCGGCATCGGCGAAGCGGCGGATGGTTCTCGTCCCGGCCCCCGGAAGGGTGCGGGCGGCGAGAGCCTGCC
GCGTCTTGCCGTGCTCGGGCGCGTCACCGGGGCCACCCTCACCGGCCTTGGCGTGCTGGCGCTGGGCTGTGGGGCCCTCG
TGCTGCTGGCCGAGGTCACGGGCCTCGTCCAGGGAGCGTTCCTGAATGCCACCGCGCTGGTGGCCACCGGGCTCGTCTCA
GCCGCCTTGGCGGCGGTGGCCGGCGGGCTGGCCCGTGCTGCCACCCGCGCCAGCGAGGAAATTCCCGACGATGCCCTCCT
CGTCACCCGCCACGGCCTGCGTGGCGAGGTGGCGATGGTGGAGGCGATGGAGGGGCCGTTCGCCGACGCGTCGGCCGCCG
CTTTTATCGGCCTCGCCCTCTTCGAGCGGGTGCTGGTGGCCGACCGGCCAGCCTTCCTCTCCGCCGTGCAGGCGGCCCAT
CATGGCAGGGCGCAGCGTTGCGAGCTGCGGCTGCGCTGTGACGGGCAGGCGGAAACCGCGCCGGCCTTCATGACCGTGGA
GGCAAGGTGCACGGCCCTGCGCTCCGGCCTGGTGCGCATCGTCTGGCGCGCGCCGTGGCAGGCCGCCGCCGCCGAACGAC
TGAAGGCCGACGACGCTGCCCGCGCCCGCGCCGAGGCGGAGGAGGCCAATGCCGCCAAGAGTCATTTCCTCGCCGCCATG
AGCCATGAGCTGCGCACCCCGCTCAACGCCATCCTCGGCTTTTCCGAGCTGCTGGCCACCGAGACCGGCGCCCCCCTCGA
CGATGCGCGGAAGGCCGACTACGCGCGCATCATCCACGAGAGCGGCCAGCATCTGCTCGGTCTGGTGAATGACATCCTGG
ATCTTTCGCGGGTGGAGGCAGGCGCCTACGAGCTGGAGCGCGAGGGCGTGGACGTGGCCGCGCTCGTCGCCGGCTGCGCC
GAGATGGTGGCCATCGATGCCGGACGCGCGGGCGTGGCGGTCAAGACGGTGTTCGCGCCCCGCCTGCCTGCCATCGATGC
CGACCGGCGGGCGTTCAAGCAGATCGTGCTCAATCTCTTGTCCAACGCGGTGAAATTCACGCCCGAGGGCGGCCGCGTGC
AGGTGAGCGTGCGCAGCGAGGGCGAAGCCGTCGCCATCCGGGTACGCGACACCGGCCCCGGCATGCGGCCGGAGGATGTG
GCGCGGCTCGGCGAGCCGTTCTTCCAGGCCGGCGACTGCACCCAGCGTGCCCGGGGCAGCGGCCTTGGCATCGCGGTGGT
GAAGGGGCTGGTGAAGCTCCACGGTGGCGATTTCCGGGTGGAGAGCGCGCCGGGGAGGGGCACCAGCGTGACCGTGACAT
TGCCGCTTGCGGCTGAGCCGGCGGTGCGGGGGGAGGGCGTGGTGGCGCCGTTCCCCACCCGCCTCGACGACACCCGCGCG
AAGAGGTTGGCATGA

Upstream 100 bases:

>100_bases
AGCCTGCCGTGGCAGGGTGTTCCCCGAAAGTGCCGGGAGACCGGTTCACAGGTTTTCACAGCATCCGGCCCGCTGAAGCG
GGCATCTGACAGGGGGCGGC

Downstream 100 bases:

>100_bases
AGCTGGAACCGGTTATGTCGGGGGGATTAAGCGAGGACGCGCCAGCGGCGGTCGACCCGTTGGCGGCGAGCGCCCGTGTG
AACGAGGAACGGCGCCTGCG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MRHLGIGEAADGSRPGPRKGAGGESLPRLAVLGRVTGATLTGLGVLALGCGALVLLAEVTGLVQGAFLNATALVATGLVS
AALAAVAGGLARAATRASEEIPDDALLVTRHGLRGEVAMVEAMEGPFADASAAAFIGLALFERVLVADRPAFLSAVQAAH
HGRAQRCELRLRCDGQAETAPAFMTVEARCTALRSGLVRIVWRAPWQAAAAERLKADDAARARAEAEEANAAKSHFLAAM
SHELRTPLNAILGFSELLATETGAPLDDARKADYARIIHESGQHLLGLVNDILDLSRVEAGAYELEREGVDVAALVAGCA
EMVAIDAGRAGVAVKTVFAPRLPAIDADRRAFKQIVLNLLSNAVKFTPEGGRVQVSVRSEGEAVAIRVRDTGPGMRPEDV
ARLGEPFFQAGDCTQRARGSGLGIAVVKGLVKLHGGDFRVESAPGRGTSVTVTLPLAAEPAVRGEGVVAPFPTRLDDTRA
KRLA

Sequences:

>Translated_484_residues
MRHLGIGEAADGSRPGPRKGAGGESLPRLAVLGRVTGATLTGLGVLALGCGALVLLAEVTGLVQGAFLNATALVATGLVS
AALAAVAGGLARAATRASEEIPDDALLVTRHGLRGEVAMVEAMEGPFADASAAAFIGLALFERVLVADRPAFLSAVQAAH
HGRAQRCELRLRCDGQAETAPAFMTVEARCTALRSGLVRIVWRAPWQAAAAERLKADDAARARAEAEEANAAKSHFLAAM
SHELRTPLNAILGFSELLATETGAPLDDARKADYARIIHESGQHLLGLVNDILDLSRVEAGAYELEREGVDVAALVAGCA
EMVAIDAGRAGVAVKTVFAPRLPAIDADRRAFKQIVLNLLSNAVKFTPEGGRVQVSVRSEGEAVAIRVRDTGPGMRPEDV
ARLGEPFFQAGDCTQRARGSGLGIAVVKGLVKLHGGDFRVESAPGRGTSVTVTLPLAAEPAVRGEGVVAPFPTRLDDTRA
KRLA
>Mature_484_residues
MRHLGIGEAADGSRPGPRKGAGGESLPRLAVLGRVTGATLTGLGVLALGCGALVLLAEVTGLVQGAFLNATALVATGLVS
AALAAVAGGLARAATRASEEIPDDALLVTRHGLRGEVAMVEAMEGPFADASAAAFIGLALFERVLVADRPAFLSAVQAAH
HGRAQRCELRLRCDGQAETAPAFMTVEARCTALRSGLVRIVWRAPWQAAAAERLKADDAARARAEAEEANAAKSHFLAAM
SHELRTPLNAILGFSELLATETGAPLDDARKADYARIIHESGQHLLGLVNDILDLSRVEAGAYELEREGVDVAALVAGCA
EMVAIDAGRAGVAVKTVFAPRLPAIDADRRAFKQIVLNLLSNAVKFTPEGGRVQVSVRSEGEAVAIRVRDTGPGMRPEDV
ARLGEPFFQAGDCTQRARGSGLGIAVVKGLVKLHGGDFRVESAPGRGTSVTVTLPLAAEPAVRGEGVVAPFPTRLDDTRA
KRLA

Specific function: Kinase required for the regulation of cell division and differentiation. Makes part of a signal transduction pathway, activating pleD by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=372, Percent_Identity=31.4516129032258, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI145693157, Length=263, Percent_Identity=36.5019011406844, Blast_Score=152, Evalue=7e-38,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=37.6569037656904, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1789149, Length=252, Percent_Identity=32.9365079365079, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI48994928, Length=250, Percent_Identity=34.8, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=30.7053941908714, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786912, Length=262, Percent_Identity=31.2977099236641, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=279, Percent_Identity=26.8817204301075, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=28.3950617283951, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=32.258064516129, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=26.4069264069264, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87082128, Length=266, Percent_Identity=28.9473684210526, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=27.1551724137931, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790861, Length=203, Percent_Identity=30.5418719211823, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789808, Length=234, Percent_Identity=26.0683760683761, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788279, Length=206, Percent_Identity=24.2718446601942, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=28.0172413793103, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789403, Length=200, Percent_Identity=30, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787894, Length=228, Percent_Identity=25, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50247; Mature: 50247

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHLGIGEAADGSRPGPRKGAGGESLPRLAVLGRVTGATLTGLGVLALGCGALVLLAEVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GLVQGAFLNATALVATGLVSAALAAVAGGLARAATRASEEIPDDALLVTRHGLRGEVAMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEE
EAMEGPFADASAAAFIGLALFERVLVADRPAFLSAVQAAHHGRAQRCELRLRCDGQAETA
EHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
PAFMTVEARCTALRSGLVRIVWRAPWQAAAAERLKADDAARARAEAEEANAAKSHFLAAM
CEEEEHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SHELRTPLNAILGFSELLATETGAPLDDARKADYARIIHESGQHLLGLVNDILDLSRVEA
HHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
GAYELEREGVDVAALVAGCAEMVAIDAGRAGVAVKTVFAPRLPAIDADRRAFKQIVLNLL
CHHHHHHCCCHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
SNAVKFTPEGGRVQVSVRSEGEAVAIRVRDTGPGMRPEDVARLGEPFFQAGDCTQRARGS
HHHEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHCCHHHCCCCHHHHHCCC
GLGIAVVKGLVKLHGGDFRVESAPGRGTSVTVTLPLAAEPAVRGEGVVAPFPTRLDDTRA
CCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCEECCCCCCCCHHHH
KRLA
HHCC
>Mature Secondary Structure
MRHLGIGEAADGSRPGPRKGAGGESLPRLAVLGRVTGATLTGLGVLALGCGALVLLAEVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GLVQGAFLNATALVATGLVSAALAAVAGGLARAATRASEEIPDDALLVTRHGLRGEVAMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEE
EAMEGPFADASAAAFIGLALFERVLVADRPAFLSAVQAAHHGRAQRCELRLRCDGQAETA
EHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
PAFMTVEARCTALRSGLVRIVWRAPWQAAAAERLKADDAARARAEAEEANAAKSHFLAAM
CEEEEHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SHELRTPLNAILGFSELLATETGAPLDDARKADYARIIHESGQHLLGLVNDILDLSRVEA
HHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
GAYELEREGVDVAALVAGCAEMVAIDAGRAGVAVKTVFAPRLPAIDADRRAFKQIVLNLL
CHHHHHHCCCHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
SNAVKFTPEGGRVQVSVRSEGEAVAIRVRDTGPGMRPEDVARLGEPFFQAGDCTQRARGS
HHHEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHCCHHHCCCCHHHHHCCC
GLGIAVVKGLVKLHGGDFRVESAPGRGTSVTVTLPLAAEPAVRGEGVVAPFPTRLDDTRA
CCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCEECCCCCCCCHHHH
KRLA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1438215; 11259647 [H]