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The map label for this gene is pgl [H]

Identifier: 154245199

GI number: 154245199

Start: 1441306

End: 1442034

Strand: Reverse

Name: pgl [H]

Synonym: Xaut_1251

Alternate gene names: 154245199

Gene position: 1442034-1441306 (Counterclockwise)

Preceding gene: 154245200

Following gene: 154245198

Centisome position: 27.16

GC content: 74.76

Gene sequence:

>729_bases
ATGACGACATCCTCCCACCCGACACCCGCCCTCCCCTTCGCCCTTGCCGCCTATGACGACCCCGCTGCCCTTGCCCGCGC
CCTGGCGGCGCACGTGGCGGAGGCGTTGCGCGCCCGCGTCGCCCGCGACGGATCGGCGAGCCTTGCCGTCTCGGGCGGCC
GCACGCCGACGCGCTTCTTCGAGACCCTGTCCGGCGCGCCGCTCGACTGGAGCCGCATCACCGTGACCCTGGTGGATGAG
CGCTGGGTGCCGGAAACATCGGATCGCTCCAACGCCGCCCTGGTGCGGCGCCACCTGCTCAAGGGACCTGCCGCCGCCGC
CCGCTTCGTACCGCTCTTTACCGGCGCGCCGACGCCGGAAGAGGGGCTCGCGGGGGCCGAGGCCGCCGTCGCCGCCCTGC
GCGCCCCGTTCGCCGCCGTGGTGCTGGGCATGGGGGATGACGGGCACACCGCCTCCTTCTTCCCCGGCGCGCCGACGCTT
GCCGCCGCCATCGATCCGGCCGGCACGGCGCGTCTCATCGCCGTGCGCGCGGAGGCGGCCGGCGAGCCGCGCATCACTTT
CACCCTGCCGCCCCTCATCTCAGCCGACCTGCTGCTCCTGCACATCGAGGGCGCGACCAAGCGCGCGGTGCTGGAGCGGG
CCGCGGCCGGTGGCAATGGGGCGGACCAGCCGATCCGCGCCGTGCTCGCCAATGCCCCAAGGCCGCTGGACGTGCTCTGG
TGTCCCTGA

Upstream 100 bases:

>100_bases
ACCGCCGGCACCTGGGGGCCCTCCGCCGCCATCGCCCTCATCGAGCGGGACGGACGGACCTGGACCGACGATGCCTGAGG
CCGCCTTTTCCGAGAAACCC

Downstream 100 bases:

>100_bases
AGCCGTTTTGACTGCCTCCCCTTTCCTTCCCGCGACCCGGGTTCCCACATTGCCCAAACAGGGCCTGATGGAGATTTCGC
GCCCATGACGTCTAACGCCC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTTSSHPTPALPFALAAYDDPAALARALAAHVAEALRARVARDGSASLAVSGGRTPTRFFETLSGAPLDWSRITVTLVDE
RWVPETSDRSNAALVRRHLLKGPAAAARFVPLFTGAPTPEEGLAGAEAAVAALRAPFAAVVLGMGDDGHTASFFPGAPTL
AAAIDPAGTARLIAVRAEAAGEPRITFTLPPLISADLLLLHIEGATKRAVLERAAAGGNGADQPIRAVLANAPRPLDVLW
CP

Sequences:

>Translated_242_residues
MTTSSHPTPALPFALAAYDDPAALARALAAHVAEALRARVARDGSASLAVSGGRTPTRFFETLSGAPLDWSRITVTLVDE
RWVPETSDRSNAALVRRHLLKGPAAAARFVPLFTGAPTPEEGLAGAEAAVAALRAPFAAVVLGMGDDGHTASFFPGAPTL
AAAIDPAGTARLIAVRAEAAGEPRITFTLPPLISADLLLLHIEGATKRAVLERAAAGGNGADQPIRAVLANAPRPLDVLW
CP
>Mature_241_residues
TTSSHPTPALPFALAAYDDPAALARALAAHVAEALRARVARDGSASLAVSGGRTPTRFFETLSGAPLDWSRITVTLVDER
WVPETSDRSNAALVRRHLLKGPAAAARFVPLFTGAPTPEEGLAGAEAAVAALRAPFAAVVLGMGDDGHTASFFPGAPTLA
AAIDPAGTARLIAVRAEAAGEPRITFTLPPLISADLLLLHIEGATKRAVLERAAAGGNGADQPIRAVLANAPRPLDVLWC
P

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=224, Percent_Identity=30.3571428571429, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321687, Length=242, Percent_Identity=24.7933884297521, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24894; Mature: 24762

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSSHPTPALPFALAAYDDPAALARALAAHVAEALRARVARDGSASLAVSGGRTPTRFF
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
ETLSGAPLDWSRITVTLVDERWVPETSDRSNAALVRRHLLKGPAAAARFVPLFTGAPTPE
HHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHEEEECCCCCCH
EGLAGAEAAVAALRAPFAAVVLGMGDDGHTASFFPGAPTLAAAIDPAGTARLIAVRAEAA
HCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHEECCCCCCEEEEEEEECCC
GEPRITFTLPPLISADLLLLHIEGATKRAVLERAAAGGNGADQPIRAVLANAPRPLDVLW
CCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEE
CP
CC
>Mature Secondary Structure 
TTSSHPTPALPFALAAYDDPAALARALAAHVAEALRARVARDGSASLAVSGGRTPTRFF
CCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
ETLSGAPLDWSRITVTLVDERWVPETSDRSNAALVRRHLLKGPAAAARFVPLFTGAPTPE
HHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHEEEECCCCCCH
EGLAGAEAAVAALRAPFAAVVLGMGDDGHTASFFPGAPTLAAAIDPAGTARLIAVRAEAA
HCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHEECCCCCCEEEEEEEECCC
GEPRITFTLPPLISADLLLLHIEGATKRAVLERAAAGGNGADQPIRAVLANAPRPLDVLW
CCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEE
CP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]