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The map label for this gene is pgi

Identifier: 154245198

GI number: 154245198

Start: 1439578

End: 1441221

Strand: Reverse

Name: pgi

Synonym: Xaut_1250

Alternate gene names: 154245198

Gene position: 1441221-1439578 (Counterclockwise)

Preceding gene: 154245199

Following gene: 154245197

Centisome position: 27.15

GC content: 69.59

Gene sequence:

>1644_bases
ATGACGTCTAACGCCCACGCGACCGACGCCGCCTTCAAGGCCCTCGCTATCGCCTGGACCACCCGCGAGGGACGCATCCT
CGACCTGTTCGCGCAACCGGACCGGTTCGAGCGCTTTTCGGTGGCCTATGGCGACCTGCTCATCGATTTCTCCAAGACCG
CCATTACCGACGACATCCTCTCCCAGCTCCTTGAGCTTGCCCGCGCCGGCGGGGTGGAGGCCCAGCGCGACGCCATGTTC
GCCGGCGACCACATCAACCTCACCGAGGATCGCGCGGTGCTGCACACCGCCTTGCGCGACCAGGCAAGCGACACCATCCA
GGTGGACGGCATCGACGTGAAGCCCGGCGTAGTGGAGACGCTCGCGCGCCTCGGCGATTTCGCCACCGGCGTGCGCGAGG
GCCGCATCGCCGGGGCGCGGGGCGGCGTCATCACCGACGTGGTCAACATCGGCATCGGCGGCTCGGACCTCGGCCCGGCC
ATGGTGACGCTGGCGCTCGCGCCTTACCACGACGGGCCGCGCTGCCACTTCGTCTCCAACGTGGACAGCGCCCACATCAC
CGACGTGCTGAAGGGGCTCGACCCCGCCACCACCCTGTTCATCGTGGCCTCCAAGACCTTCACCACGGTGGAGACCATGA
CCAACGCCGCCACCGCCCGCGCCTTCATCGTGAATGCGCTGGGCGAGGACGCGGTGGGCGCCCATTTCGCCGCCGTCTCG
ACCGCGCTCGACAAGGTGGGGGCGTTCGGCATCCCGGCCGATCGGATCTTCGGCTTCTGGGACTGGGTGGGCGGGCGCTA
TTCGGTGTGGTCGGCCATCGGCCTGCCGCTGATGCTCGCCATCGGCCCGGACCGGTTCCGGGAATTCCTCGCCGGCGCGG
CGGCCATGGACGAGCACTTCCGCTCCGCCGTTCTCGACCAGAACCTGCCGGTGCTGCTGGGACTCATCGGCCTATGGCAT
CGCAATGCCTGCGGCTTCCCGAGCCGGGCCATCATCCCCTACGACCAGCGCCTCGCCCGGCTGCCGGCCTATCTCCAGCA
GCTCGACATGGAGAGCAACGGCAAGAGCGTGACGCGGGACGGGGCCGCCGTCAGCCGGCCCACCGGCCCCATCGTGTGGG
GCGAGCCCGGCACCAATGCGCAGCATGCCTTCTTCCAGCTGCTGCACCAGGGCACGGACATCGTGCCGGTGGAATTCCTG
GTGGGGGCGCAGAGCCACGAGCCGGCGCTGAAGGACCACCAGGACCTGCTGGTGGCCAATTGCCTGGCCCAGTCCGAGGC
GCTCATGCGCGGGCGCACGCTGGAGGAGGCGACGGCCCAGCTCCGGGCCAAGGGCATCAGCGAGGACAAGGTGGCGGAGA
TCGCGCCCCATCGCGTCTTCCCCGGCGACCGCCCGTCGCTGACCATCGCCTATGCCACCCTCGACCCGTTCACCCTCGGG
CGCATCATCGCGCTCTACGAGCACCGGGTGTTCGTGGAAGCGGCGGTGTGGGGCATCAATGGCTTCGACCAGTGGGGCGT
GGAGCTGGGCAAGGAACTCGCCACCCAGTTCCTGCCCGCCGTCACCGGCGGTGCACTGCCGCCGAGCGCATCGGCATCCA
CCTCCGGCCTCATCGCCCATCTCGACGCGGTCGCTGGGGGCTGA

Upstream 100 bases:

>100_bases
GCTCTGGTGTCCCTGAAGCCGTTTTGACTGCCTCCCCTTTCCTTCCCGCGACCCGGGTTCCCACATTGCCCAAACAGGGC
CTGATGGAGATTTCGCGCCC

Downstream 100 bases:

>100_bases
GCCCTTCCCTATCGGCAGGTAGCGCGTTCTTCCCGTCAGCCCTCGCATGTGCGATGCTGCTATGCAGCAATGCGGGGGTC
CCTCTGCGTATTATGTATAC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MTSNAHATDAAFKALAIAWTTREGRILDLFAQPDRFERFSVAYGDLLIDFSKTAITDDILSQLLELARAGGVEAQRDAMF
AGDHINLTEDRAVLHTALRDQASDTIQVDGIDVKPGVVETLARLGDFATGVREGRIAGARGGVITDVVNIGIGGSDLGPA
MVTLALAPYHDGPRCHFVSNVDSAHITDVLKGLDPATTLFIVASKTFTTVETMTNAATARAFIVNALGEDAVGAHFAAVS
TALDKVGAFGIPADRIFGFWDWVGGRYSVWSAIGLPLMLAIGPDRFREFLAGAAAMDEHFRSAVLDQNLPVLLGLIGLWH
RNACGFPSRAIIPYDQRLARLPAYLQQLDMESNGKSVTRDGAAVSRPTGPIVWGEPGTNAQHAFFQLLHQGTDIVPVEFL
VGAQSHEPALKDHQDLLVANCLAQSEALMRGRTLEEATAQLRAKGISEDKVAEIAPHRVFPGDRPSLTIAYATLDPFTLG
RIIALYEHRVFVEAAVWGINGFDQWGVELGKELATQFLPAVTGGALPPSASASTSGLIAHLDAVAGG

Sequences:

>Translated_547_residues
MTSNAHATDAAFKALAIAWTTREGRILDLFAQPDRFERFSVAYGDLLIDFSKTAITDDILSQLLELARAGGVEAQRDAMF
AGDHINLTEDRAVLHTALRDQASDTIQVDGIDVKPGVVETLARLGDFATGVREGRIAGARGGVITDVVNIGIGGSDLGPA
MVTLALAPYHDGPRCHFVSNVDSAHITDVLKGLDPATTLFIVASKTFTTVETMTNAATARAFIVNALGEDAVGAHFAAVS
TALDKVGAFGIPADRIFGFWDWVGGRYSVWSAIGLPLMLAIGPDRFREFLAGAAAMDEHFRSAVLDQNLPVLLGLIGLWH
RNACGFPSRAIIPYDQRLARLPAYLQQLDMESNGKSVTRDGAAVSRPTGPIVWGEPGTNAQHAFFQLLHQGTDIVPVEFL
VGAQSHEPALKDHQDLLVANCLAQSEALMRGRTLEEATAQLRAKGISEDKVAEIAPHRVFPGDRPSLTIAYATLDPFTLG
RIIALYEHRVFVEAAVWGINGFDQWGVELGKELATQFLPAVTGGALPPSASASTSGLIAHLDAVAGG
>Mature_546_residues
TSNAHATDAAFKALAIAWTTREGRILDLFAQPDRFERFSVAYGDLLIDFSKTAITDDILSQLLELARAGGVEAQRDAMFA
GDHINLTEDRAVLHTALRDQASDTIQVDGIDVKPGVVETLARLGDFATGVREGRIAGARGGVITDVVNIGIGGSDLGPAM
VTLALAPYHDGPRCHFVSNVDSAHITDVLKGLDPATTLFIVASKTFTTVETMTNAATARAFIVNALGEDAVGAHFAAVST
ALDKVGAFGIPADRIFGFWDWVGGRYSVWSAIGLPLMLAIGPDRFREFLAGAAAMDEHFRSAVLDQNLPVLLGLIGLWHR
NACGFPSRAIIPYDQRLARLPAYLQQLDMESNGKSVTRDGAAVSRPTGPIVWGEPGTNAQHAFFQLLHQGTDIVPVEFLV
GAQSHEPALKDHQDLLVANCLAQSEALMRGRTLEEATAQLRAKGISEDKVAEIAPHRVFPGDRPSLTIAYATLDPFTLGR
IIALYEHRVFVEAAVWGINGFDQWGVELGKELATQFLPAVTGGALPPSASASTSGLIAHLDAVAGG

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

Organism=Homo sapiens, GI18201905, Length=521, Percent_Identity=51.8234165067178, Blast_Score=556, Evalue=1e-158,
Organism=Homo sapiens, GI296080693, Length=521, Percent_Identity=48.3685220729367, Blast_Score=508, Evalue=1e-144,
Organism=Escherichia coli, GI1790457, Length=541, Percent_Identity=49.9075785582255, Blast_Score=527, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI71996708, Length=544, Percent_Identity=49.2647058823529, Blast_Score=536, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI71996703, Length=544, Percent_Identity=49.2647058823529, Blast_Score=536, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6319673, Length=515, Percent_Identity=49.5145631067961, Blast_Score=504, Evalue=1e-143,
Organism=Drosophila melanogaster, GI24651916, Length=545, Percent_Identity=49.3577981651376, Blast_Score=540, Evalue=1e-153,
Organism=Drosophila melanogaster, GI24651914, Length=545, Percent_Identity=49.3577981651376, Blast_Score=540, Evalue=1e-153,
Organism=Drosophila melanogaster, GI17737445, Length=545, Percent_Identity=49.3577981651376, Blast_Score=540, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_XANP2 (A7IEQ6)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001416156.1
- ProteinModelPortal:   A7IEQ6
- SMR:   A7IEQ6
- STRING:   A7IEQ6
- GeneID:   5423174
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_1250
- eggNOG:   COG0166
- HOGENOM:   HBG352954
- OMA:   INAQHAF
- ProtClustDB:   CLSK979384
- BioCyc:   XAUT78245:XAUT_1250-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189
- Gene3D:   G3DSA:1.10.1390.10
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 58313; Mature: 58182

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 382-382 ACT_SITE 511-511

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNAHATDAAFKALAIAWTTREGRILDLFAQPDRFERFSVAYGDLLIDFSKTAITDDIL
CCCCCCCHHHHHHEEEEEEECCCCCEEEEECCCCCHHHHHEEHHHEEEECCHHHHHHHHH
SQLLELARAGGVEAQRDAMFAGDHINLTEDRAVLHTALRDQASDTIQVDGIDVKPGVVET
HHHHHHHHHCCCCCHHCCEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCEECCCHHHHH
LARLGDFATGVREGRIAGARGGVITDVVNIGIGGSDLGPAMVTLALAPYHDGPRCHFVSN
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHEEEEECCCCCCCEEEECC
VDSAHITDVLKGLDPATTLFIVASKTFTTVETMTNAATARAFIVNALGEDAVGAHFAAVS
CCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TALDKVGAFGIPADRIFGFWDWVGGRYSVWSAIGLPLMLAIGPDRFREFLAGAAAMDEHF
HHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHH
RSAVLDQNLPVLLGLIGLWHRNACGFPSRAIIPYDQRLARLPAYLQQLDMESNGKSVTRD
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECC
GAAVSRPTGPIVWGEPGTNAQHAFFQLLHQGTDIVPVEFLVGAQSHEPALKDHQDLLVAN
CCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEHHHEECCCCCCCCHHHHHHHHHHH
CLAQSEALMRGRTLEEATAQLRAKGISEDKVAEIAPHRVFPGDRPSLTIAYATLDPFTLG
HHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHH
RIIALYEHRVFVEAAVWGINGFDQWGVELGKELATQFLPAVTGGALPPSASASTSGLIAH
HHHHHHHHHHEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
LDAVAGG
HHHHCCC
>Mature Secondary Structure 
TSNAHATDAAFKALAIAWTTREGRILDLFAQPDRFERFSVAYGDLLIDFSKTAITDDIL
CCCCCCHHHHHHEEEEEEECCCCCEEEEECCCCCHHHHHEEHHHEEEECCHHHHHHHHH
SQLLELARAGGVEAQRDAMFAGDHINLTEDRAVLHTALRDQASDTIQVDGIDVKPGVVET
HHHHHHHHHCCCCCHHCCEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCEECCCHHHHH
LARLGDFATGVREGRIAGARGGVITDVVNIGIGGSDLGPAMVTLALAPYHDGPRCHFVSN
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHEEEEECCCCCCCEEEECC
VDSAHITDVLKGLDPATTLFIVASKTFTTVETMTNAATARAFIVNALGEDAVGAHFAAVS
CCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TALDKVGAFGIPADRIFGFWDWVGGRYSVWSAIGLPLMLAIGPDRFREFLAGAAAMDEHF
HHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHH
RSAVLDQNLPVLLGLIGLWHRNACGFPSRAIIPYDQRLARLPAYLQQLDMESNGKSVTRD
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECC
GAAVSRPTGPIVWGEPGTNAQHAFFQLLHQGTDIVPVEFLVGAQSHEPALKDHQDLLVAN
CCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEHHHEECCCCCCCCHHHHHHHHHHH
CLAQSEALMRGRTLEEATAQLRAKGISEDKVAEIAPHRVFPGDRPSLTIAYATLDPFTLG
HHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHH
RIIALYEHRVFVEAAVWGINGFDQWGVELGKELATQFLPAVTGGALPPSASASTSGLIAH
HHHHHHHHHHEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
LDAVAGG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA